"RNA, Small Nucleolar" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small nuclear RNAs that are involved in the processing of pre-ribosomal RNA in the nucleolus. Box C/D containing snoRNAs (U14, U15, U16, U20, U21 and U24-U63) direct site-specific methylation of various ribose moieties. Box H/ACA containing snoRNAs (E2, E3, U19, U23, and U64-U72) direct the conversion of specific uridines to pseudouridine. Site-specific cleavages resulting in the mature ribosomal RNAs are directed by snoRNAs U3, U8, U14, U22 and the snoRNA components of RNase MRP and RNase P.
| Descriptor ID |
D020537
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| MeSH Number(s) |
D13.444.735.628.818.800 D13.444.735.790.552.937.800
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "RNA, Small Nucleolar".
Below are MeSH descriptors whose meaning is more specific than "RNA, Small Nucleolar".
This graph shows the total number of publications written about "RNA, Small Nucleolar" by people in this website by year, and whether "RNA, Small Nucleolar" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA, Small Nucleolar" by people in Profiles.
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Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation. Cell Metab. 2023 08 08; 35(8):1457-1473.e13.
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Leukoencephalopathy with calcifications and cysts: Genetic and phenotypic spectrum. Am J Med Genet A. 2021 01; 185(1):15-25.
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Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein. Genes Dev. 2017 09 15; 31(18):1847-1857.
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The Canonical Poly (A) Polymerase PAP1 Polyadenylates Non-Coding RNAs and Is Essential for snoRNA Biogenesis in Trypanosoma brucei. J Mol Biol. 2017 10 27; 429(21):3301-3318.
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Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts. Nat Genet. 2016 10; 48(10):1185-92.
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SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism. Mol Oncol. 2016 10; 10(8):1266-82.
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Long noncoding RNAs: Re-writing dogmas of RNA processing and stability. Biochim Biophys Acta. 2016 Jan; 1859(1):128-38.
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Genome-wide analysis of small nucleolar RNAs of Leishmania major reveals a rich repertoire of RNAs involved in modification and processing of rRNA. RNA Biol. 2015; 12(11):1222-55.
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Nonsense-mediated RNA decay: at the 'cutting edge' of regulated snoRNA production. Genes Dev. 2014 Nov 15; 28(22):2447-9.
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The Trypanosoma brucei telomerase RNA (TER) homologue binds core proteins of the C/D snoRNA family. FEBS Lett. 2013 May 02; 587(9):1399-404.