"Enediynes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds with triple bonds to each side of a double bond. Many of these are CYTOTOXINS and are researched for use as CYTOTOXIC ANTIBIOTICS.
| Descriptor ID |
D053281
|
| MeSH Number(s) |
D02.455.326.271.244 D02.455.326.397.662.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Enediynes".
Below are MeSH descriptors whose meaning is more specific than "Enediynes".
This graph shows the total number of publications written about "Enediynes" by people in this website by year, and whether "Enediynes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Enediynes" by people in Profiles.
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The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. Acta Crystallogr F Struct Biol Commun. 2022 Jan 01; 78(Pt 1):1-7.
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Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study. Lancet Oncol. 2012 Apr; 13(4):403-11.
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The role of gemtuzumab ozogamicin in acute leukaemia therapy. Br J Haematol. 2006 Feb; 132(4):398-409.
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A phase 2 study of the cytotoxic immunoconjugate CMB-401 (hCTM01-calicheamicin) in patients with platinum-sensitive recurrent epithelial ovarian carcinoma. Cancer Immunol Immunother. 2003 Apr; 52(4):243-8.