"Acidosis, Lactic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
Descriptor ID |
D000140
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MeSH Number(s) |
C18.452.076.176.180
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acidosis, Lactic".
Below are MeSH descriptors whose meaning is more specific than "Acidosis, Lactic".
This graph shows the total number of publications written about "Acidosis, Lactic" by people in this website by year, and whether "Acidosis, Lactic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 |
2005 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 1 | 2 |
2015 | 1 | 2 | 3 |
2016 | 1 | 0 | 1 |
2017 | 1 | 1 | 2 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
2021 | 0 | 1 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acidosis, Lactic" by people in Profiles.
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Heteroplasmic pathogenic m.12315G>A variant in MT-TL2 presenting with MELAS syndrome and depletion of nitric oxide donors. Am J Med Genet A. 2024 03; 194(3):e63461.
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Metabolic impact of pathogenic variants in the mitochondrial glutamyl-tRNA synthetase EARS2. J Inherit Metab Dis. 2021 07; 44(4):949-960.
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Persistent Lactic Acidosis in an 18-month-old Girl Status Post Bone Marrow Transplant. Pediatr Rev. 2020 Oct; 41(Suppl 1):S20-S22.
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A Pharmacokinetic Analysis of Hemodialysis for Metformin-Associated Lactic Acidosis. J Med Toxicol. 2021 01; 17(1):70-74.
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Case 1: Preterm Neonate with Hydrops and Lactic Acidosis. Neoreviews. 2019 09; 20(9):e520-e523.
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Expanding the phenotype of SLC25A42-associated mitochondrial encephalomyopathy. Clin Genet. 2018 05; 93(5):1097-1102.
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Molecular and clinical spectra of FBXL4 deficiency. Hum Mutat. 2017 12; 38(12):1649-1659.
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FBXL4 defects are common in patients with congenital lactic acidemia and encephalomyopathic mitochondrial DNA depletion syndrome. Clin Genet. 2017 Apr; 91(4):634-639.
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Trimethoprim/Sulfamethoxazole-Induced Severe Lactic Acidosis: A Case Report and Review of the Literature. Medicine (Baltimore). 2016 Apr; 95(17):e3478.
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MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options. Mol Genet Metab. 2015 Sep-Oct; 116(1-2):4-12.