"Perforant Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pathway of fibers that originates in the lateral part of the ENTORHINAL CORTEX, perforates the SUBICULUM of the HIPPOCAMPUS, and runs into the stratum moleculare of the hippocampus, where these fibers synapse with others that go to the DENTATE GYRUS where the pathway terminates. It is also known as the perforating fasciculus.
Descriptor ID |
D019580
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MeSH Number(s) |
A08.186.211.464.730 A08.612.600
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Concept/Terms |
Perforant Pathway- Perforant Pathway
- Pathway, Perforant
- Pathways, Perforant
- Perforant Pathways
- Perforant Path
- Path, Perforant
- Paths, Perforant
- Perforant Paths
- Perforating Fasciculus
- Fasciculus, Perforating
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Below are MeSH descriptors whose meaning is more general than "Perforant Pathway".
Below are MeSH descriptors whose meaning is more specific than "Perforant Pathway".
This graph shows the total number of publications written about "Perforant Pathway" by people in this website by year, and whether "Perforant Pathway" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 |
2001 | 1 | 2 | 3 |
2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2014 | 0 | 2 | 2 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Perforant Pathway" by people in Profiles.
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Glutamate-activated BK channel complexes formed with NMDA receptors. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):E9006-E9014.
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Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability. Cell Rep. 2016 07 19; 16(3):793-804.
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Dopamine and norepinephrine receptors participate in methylphenidate enhancement of in vivo hippocampal synaptic plasticity. Neuropharmacology. 2015 Mar; 90:23-32.
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Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Mol Neurobiol. 2015 Dec; 52(3):1067-1076.
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Neuropsychological evidence for the functional role of the uncinate fasciculus in semantic control. Neuropsychologia. 2013 Apr; 51(5):789-801.
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Diffusion tensor imaging of the perforant pathway zone and its relation to memory function in patients with severe traumatic brain injury. J Neurotrauma. 2011 May; 28(5):711-25.
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Addictive nicotine alters local circuit inhibition during the induction of in vivo hippocampal synaptic potentiation. J Neurosci. 2010 May 05; 30(18):6443-53.
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Combination of hypothyroidism and stress abolishes early LTP in the CA1 but not dentate gyrus of hippocampus of adult rats. Brain Res. 2001 Dec 20; 922(2):250-60.
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Presynaptic Ca2+ channels and neurotransmitter release at the terminal of a mouse cortical neuron. J Neurosci. 2001 Jun 01; 21(11):3721-8.
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Attenuated LTP in hippocampal dentate gyrus neurons of mice deficient in the PAF receptor. J Neurophysiol. 2001 Jan; 85(1):384-90.