JOHN TAINER to Catalytic Domain
This is a "connection" page, showing publications JOHN TAINER has written about Catalytic Domain.
Connection Strength
2.077
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Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors. Prog Biophys Mol Biol. 2021 08; 163:171-186.
Score: 0.179
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Structural Control of Nonnative Ligand Binding in Engineered Mutants of Phosphoenolpyruvate Carboxykinase. Biochemistry. 2018 12 04; 57(48):6688-6700.
Score: 0.153
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Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability. Nat Commun. 2017 06 27; 8:15855.
Score: 0.139
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Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor. Structure. 2016 12 06; 24(12):2067-2079.
Score: 0.133
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Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity. Biochemistry. 2014 Apr 08; 53(13):2153-65.
Score: 0.111
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Insights into FlaI functions in archaeal motor assembly and motility from structures, conformations, and genetics. Mol Cell. 2013 Mar 28; 49(6):1069-82.
Score: 0.103
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Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. J Biol Chem. 2013 Mar 22; 288(12):8445-8455.
Score: 0.102
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Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases. Trends Biochem Sci. 2012 Feb; 37(2):74-84.
Score: 0.094
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XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair (Amst). 2011 Jul 15; 10(7):697-713.
Score: 0.091
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Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell. 2011 Apr 15; 145(2):198-211.
Score: 0.090
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Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis. J Mol Biol. 2009 Feb 06; 385(5):1534-55.
Score: 0.077
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DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy. DNA Repair (Amst). 2007 Aug 01; 6(8):1100-15.
Score: 0.069
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Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair. Cell. 2004 Jan 09; 116(1):39-50.
Score: 0.055
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Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum. Proteins. 2003 Apr 01; 51(1):137-46.
Score: 0.052
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Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: insertion of valine C gamma into the substrate access channel. Biochemistry. 2003 Mar 18; 42(10):2781-9.
Score: 0.052
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Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus. J Biol Chem. 2021 08; 297(2):100921.
Score: 0.046
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Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication. J Mol Biol. 2001 Mar 23; 307(2):541-56.
Score: 0.045
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An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Prog Biophys Mol Biol. 2021 08; 163:143-159.
Score: 0.045
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Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding. EMBO J. 2000 Apr 03; 19(7):1719-30.
Score: 0.042
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Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O2 activation. Proc Natl Acad Sci U S A. 2019 03 19; 116(12):5370-5375.
Score: 0.039
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MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nat Struct Biol. 1998 Dec; 5(12):1058-64.
Score: 0.038
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Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nat Commun. 2018 02 06; 9(1):512.
Score: 0.036
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Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex. Nucleic Acids Res. 2017 Jun 02; 45(10):6238-6251.
Score: 0.035
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Perchlorate Reductase Is Distinguished by Active Site Aromatic Gate Residues. J Biol Chem. 2016 Apr 22; 291(17):9190-202.
Score: 0.032
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Intact functional fourteen-subunit respiratory membrane-bound [NiFe]-hydrogenase complex of the hyperthermophilic archaeon Pyrococcus furiosus. J Biol Chem. 2014 Jul 11; 289(28):19364-72.
Score: 0.028
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Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase. Nucleic Acids Res. 2012 Jul; 40(13):6070-81.
Score: 0.024
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Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants. J Biol Chem. 2012 Apr 06; 287(15):12060-9.
Score: 0.024
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Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ions. J Biol Chem. 2011 Sep 02; 286(35):30878-30887.
Score: 0.023
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Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases. J Biol Chem. 2010 Mar 12; 285(11):8185-95.
Score: 0.021
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Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis. Biochemistry. 2009 Apr 21; 48(15):3417-24.
Score: 0.020
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Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. EMBO J. 2006 Jul 26; 25(14):3389-97.
Score: 0.016
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A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. J Mol Biol. 2006 May 19; 358(5):1229-43.
Score: 0.016
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Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase. J Biol Chem. 2004 Nov 05; 279(45):46930-9.
Score: 0.014
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Role of hydrogen bonding in the active site of human manganese superoxide dismutase. Biochemistry. 2004 Jun 08; 43(22):7038-45.
Score: 0.014
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The rad50 signature motif: essential to ATP binding and biological function. J Mol Biol. 2004 Jan 23; 335(4):937-51.
Score: 0.014
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Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1. J Biol Chem. 1998 Oct 16; 273(42):27154-61.
Score: 0.009