JOHN TAINER to Protein Binding
This is a "connection" page, showing publications JOHN TAINER has written about Protein Binding.
Connection Strength
2.374
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X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology. Protein Sci. 2021 09; 30(9):1735-1756.
Score: 0.123
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Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proc Natl Acad Sci U S A. 2020 06 23; 117(25):14127-14138.
Score: 0.115
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Uncovering the secrets of protein interactions with the DNA enforcing genomic stability. Prog Biophys Mol Biol. 2017 08; 127:89-92.
Score: 0.094
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An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex. J Biol Chem. 2016 12 30; 291(53):26987-27006.
Score: 0.089
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Emerging critical roles of Fe-S clusters in DNA replication and repair. Biochim Biophys Acta. 2015 Jun; 1853(6):1253-71.
Score: 0.079
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Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair. Prog Biophys Mol Biol. 2015 Mar; 117(2-3):182-193.
Score: 0.079
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DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17308-13.
Score: 0.072
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Insights into FlaI functions in archaeal motor assembly and motility from structures, conformations, and genetics. Mol Cell. 2013 Mar 28; 49(6):1069-82.
Score: 0.069
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Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. J Biol Chem. 2013 Mar 22; 288(12):8445-8455.
Score: 0.069
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Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17672-7.
Score: 0.063
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XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. J Biol Chem. 2011 Sep 16; 286(37):32638-50.
Score: 0.062
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P53 conformational switching for selectivity may reveal a general solution for specific DNA binding. EMBO J. 2011 Jun 01; 30(11):2099-100.
Score: 0.061
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Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem. 2010 Jan 08; 285(2):1414-23.
Score: 0.055
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Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature. 2009 Jun 11; 459(7248):808-13.
Score: 0.053
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Hexameric structures of the archaeal secretion ATPase GspE and implications for a universal secretion mechanism. EMBO J. 2007 Feb 07; 26(3):878-90.
Score: 0.045
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Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications. Nucleic Acids Res. 2006; 34(20):6023-33.
Score: 0.045
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DNA binding and nucleotide flipping by the human DNA repair protein AGT. Nat Struct Mol Biol. 2004 Aug; 11(8):714-20.
Score: 0.038
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Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair. Cell. 2004 Jan 09; 116(1):39-50.
Score: 0.037
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Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum. Proteins. 2003 Apr 01; 51(1):137-46.
Score: 0.035
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Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures. Curr Opin Struct Biol. 2003 Apr; 13(2):249-55.
Score: 0.035
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Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2207408119.
Score: 0.033
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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature. 2002 Aug 01; 418(6897):562-6.
Score: 0.033
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The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases. Int J Med Microbiol. 2002 Feb; 291(6-7):523-9.
Score: 0.032
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DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. Prog Nucleic Acid Res Mol Biol. 2001; 68:315-47.
Score: 0.030
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Mechanism of efficient double-strand break repair by a long non-coding RNA. Nucleic Acids Res. 2020 11 04; 48(19):10953-10972.
Score: 0.029
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Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O(6)-alkylguanine-DNA alkyltransferase. Mutat Res. 2000 Aug 30; 460(3-4):151-63.
Score: 0.029
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Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions. Structure. 2000 Aug 15; 8(8):841-50.
Score: 0.029
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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]. Nature. 2000 Jan 27; 403(6768):451-6.
Score: 0.028
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SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair. Nucleic Acids Res. 2019 11 04; 47(19):10181-10201.
Score: 0.027
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Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis. Structure. 2019 10 01; 27(10):1485-1496.e4.
Score: 0.027
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Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase. J Mol Biol. 1999 Mar 26; 287(2):331-46.
Score: 0.026
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Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. EMBO J. 1998 Sep 01; 17(17):5214-26.
Score: 0.025
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Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nat Commun. 2018 02 06; 9(1):512.
Score: 0.024
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Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex. Nucleic Acids Res. 2017 Jun 02; 45(10):6238-6251.
Score: 0.023
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Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1. Elife. 2017 02 23; 6.
Score: 0.023
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Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome. Structure. 2017 01 03; 25(1):157-166.
Score: 0.023
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A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature. 1996 Nov 07; 384(6604):87-92.
Score: 0.022
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Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Mol Cell. 2016 11 17; 64(4):688-703.
Score: 0.022
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HU multimerization shift controls nucleoid compaction. Sci Adv. 2016 07; 2(7):e1600650.
Score: 0.022
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Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1. Cell. 1996 Mar 22; 84(6):863-74.
Score: 0.021
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Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA. Cell. 1995 Sep 08; 82(5):701-8.
Score: 0.021
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Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining. Nucleic Acids Res. 2015 Aug 18; 43(14):7021-31.
Score: 0.020
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Structurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response. Structure. 2015 Apr 07; 23(4):724-733.
Score: 0.020
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Predicting molecular interactions and inducible complementarity: fragment docking of Fab-peptide complexes. Proteins. 1994 Sep; 20(1):15-24.
Score: 0.019
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ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. EMBO J. 2014 Mar 03; 33(5):482-500.
Score: 0.018
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Molecular recognition in DNA-binding proteins and enzymes. Curr Opin Biotechnol. 1993 Aug; 4(4):474-83.
Score: 0.018
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The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol. 2013 Jul 10; 425(13):2359-71.
Score: 0.017
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XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. Biochem Cell Biol. 2013 Feb; 91(1):31-41.
Score: 0.017
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Rational design and expression of a heparin-targeted human superoxide dismutase. Biochem Biophys Res Commun. 1993 Jan 15; 190(1):250-6.
Score: 0.017
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A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Res. 2013 Feb 01; 41(4):2313-27.
Score: 0.017
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Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2. Structure. 2013 Jan 08; 21(1):154-166.
Score: 0.017
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Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-p interactions. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18755-60.
Score: 0.017
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Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines. Mol Cell. 2012 Jul 13; 47(1):50-60.
Score: 0.016
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Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8528-33.
Score: 0.016
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Structure of an essential type IV pilus biogenesis protein provides insights into pilus and type II secretion systems. J Mol Biol. 2012 May 25; 419(1-2):110-24.
Score: 0.016
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DNA charge transport as a first step in coordinating the detection of lesions by repair proteins. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):1856-61.
Score: 0.016
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Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants. J Biol Chem. 2012 Apr 06; 287(15):12060-9.
Score: 0.016
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Neutralizing mutations of carboxylates that bind metal 2 in T5 flap endonuclease result in an enzyme that still requires two metal ions. J Biol Chem. 2011 Sep 02; 286(35):30878-30887.
Score: 0.015
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The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome. Cell Cycle. 2011 Jun 15; 10(12):1998-2007.
Score: 0.015
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Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry. 2010 Apr 06; 49(13):2880-9.
Score: 0.014
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Substrate recognition and catalysis by flap endonucleases and related enzymes. Biochem Soc Trans. 2010 Apr; 38(2):433-7.
Score: 0.014
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Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase. Nucleic Acids Res. 2009 Oct; 37(18):6161-73.
Score: 0.014
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Molecular mimicry of SUMO promotes DNA repair. Nat Struct Mol Biol. 2009 May; 16(5):509-16.
Score: 0.013
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SUMO-targeted ubiquitin ligases in genome stability. EMBO J. 2007 Sep 19; 26(18):4089-101.
Score: 0.012
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Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J Mol Biol. 2007 Nov 02; 373(4):877-90.
Score: 0.012
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A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Mol Cell. 2006 Oct 20; 24(2):279-91.
Score: 0.011
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Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2. Biochemistry. 2005 Sep 13; 44(36):11997-2008.
Score: 0.010
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Hydrogen bonding in human manganese superoxide dismutase containing 3-fluorotyrosine. Biophys J. 2005 Dec; 89(6):4171-9.
Score: 0.010
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The ATPase activity of BfpD is greatly enhanced by zinc and allosteric interactions with other Bfp proteins. J Biol Chem. 2005 Jul 01; 280(26):24839-48.
Score: 0.010
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Interaction interface of human flap endonuclease-1 with its DNA substrates. J Biol Chem. 2004 Jun 04; 279(23):24394-402.
Score: 0.009
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The rad50 signature motif: essential to ATP binding and biological function. J Mol Biol. 2004 Jan 23; 335(4):937-51.
Score: 0.009
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Structural basis for endothelial nitric oxide synthase binding to calmodulin. EMBO J. 2003 Feb 17; 22(4):766-75.
Score: 0.009
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Design of a monomeric human glutathione transferase GSTP1, a structurally stable but catalytically inactive protein. Protein Eng. 2002 Oct; 15(10):827-34.
Score: 0.008
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Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):107-12.
Score: 0.008
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Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457. Biochemistry. 2001 Oct 30; 40(43):12826-32.
Score: 0.008
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Unraveling the effect of changes in conformation and compactness at the antibody V(L)-V(H) interface upon antigen binding. J Mol Recognit. 1999 Jul-Aug; 12(4):267-75.
Score: 0.007
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Mutation of an active site residue in Escherichia coli uracil-DNA glycosylase: effect on DNA binding, uracil inhibition and catalysis. Biochemistry. 1999 Apr 13; 38(15):4834-45.
Score: 0.007
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The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J. 1997 Nov 03; 16(21):6548-58.
Score: 0.006
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Electrostatic orientation of the electron-transfer complex between plastocyanin and cytochrome c. J Biol Chem. 1991 Jul 15; 266(20):13431-41.
Score: 0.004