MEK Inhibitor Selumetinib (AZD6244; ARRY-142886) Prevents Lung Metastasis in a Triple-Negative Breast Cancer Xenograft Model.

MEK Inhibitor Selumetinib (AZD6244; ARRY-142886) Prevents Lung Metastasis in a Triple-Negative Breast Cancer Xenograft Model. Mol Cancer Ther. 2015 Dec; 14(12):2773-81.

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subject areas

Animals
Apoptosis
Benzimidazoles
Cell Line, Tumor
Cell Proliferation
Female
Humans
Lung Neoplasms
MAP Kinase Kinase Kinase 1
Mice
Protein Kinase Inhibitors
Triple Negative Breast Neoplasms
Xenograft Model Antitumor Assays