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Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade.
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Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade.
Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade. Cancer Immunol Res. 2014 Jul; 2(7):643-54.
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PubMed
subject areas
Animals
Antibodies, Monoclonal
Antigens, Neoplasm
Antineoplastic Combined Chemotherapy Protocols
B7-H1 Antigen
CD8-Positive T-Lymphocytes
Cell Line, Tumor
CTLA-4 Antigen
Cytokines
Dose-Response Relationship, Drug
Humans
Immunocompetence
Indoles
Ipilimumab
Lymphocyte Count
Lymphocytes, Tumor-Infiltrating
Male
Melanoma
Mice, Inbred C57BL
Middle Aged
Proto-Oncogene Proteins B-raf
Sulfonamides
T-Lymphocytes, Regulatory
Tumor Escape
Xenograft Model Antitumor Assays
authors with profiles
JENNIFER WARGO