ULRICH STRYCH

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
Email
vCardDownload vCard

    Collapse Overview 
    Collapse keywords

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chen WH, Strych U, Bottazzi ME, Lin YP. Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights. Expert Rev Vaccines. 2022 Jul 22; 1-13. PMID: 35836340.
      Citations:    Fields:    
    2. Chen YL, Marcinkiewicz AL, Nowak TA, Tyagi Kundu R, Liu Z, Strych U, Bottazzi ME, Chen WH, Lin YP. CspZ FH-Binding Sites as Epitopes Promote Antibody-Mediated Lyme Borreliae Clearance. Infect Immun. 2022 Jul 21; 90(7):e0006222. PMID: 35861564.
      Citations:    Fields:    Translation:AnimalsCells
    3. Pollet J, Strych U, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Jose Villar M, Rani Thimmiraju S, Lopez B, Gillespie PM, Ronca S, Kimata JT, Reers M, Paradkar V, Hotez PJ, Elena Bottazzi M. Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern. Vaccine. 2022 06 09; 40(26):3655-3663. PMID: 35568591.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Rawal K, Sinha R, Nath SK, Preeti P, Kumari P, Gupta S, Sharma T, Strych U, Hotez P, Bottazzi ME. Vaxi-DL: A web-based deep learning server to identify potential vaccine candidates. Comput Biol Med. 2022 06; 145:105401. PMID: 35381451.
      Citations: 1     Fields:    Translation:Animals
    5. Pollet J, Strych U, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Villar MJ, Thimmiraju SR, Lopez B, Gillespie PM, Ronca S, Kimata JT, Reers M, Paradkar V, Hotez P, Bottazzi ME. Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern. bioRxiv. 2022 Mar 22. PMID: 34268512.
      Citations: 1     
    6. Bartsch SM, O'Shea KJ, Chin KL, Strych U, Ferguson MC, Bottazzi ME, Wedlock PT, Cox SN, Siegmund SS, Hotez PJ, Lee BY. Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study. Lancet Public Health. 2022 04; 7(4):e356-e365. PMID: 35276093.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    7. Wei J, Hegde VL, Yanamandra AV, O'Hara MP, Keegan B, Jones KM, Strych U, Bottazzi ME, Zhan B, Sastry KJ, Hotez PJ. Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice. Front Immunol. 2022; 13:800295. PMID: 35197976.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    8. Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, Prevost-Reilly A, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Sage PT, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Sci Transl Med. 2022 Jan 26; 14(629):eabj5305. PMID: 34783582.
      Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. Chen WH, Pollet J, Strych U, Lee J, Liu Z, Kundu RT, Versteeg L, Villar MJ, Adhikari R, Wei J, Poveda C, Keegan B, Bailey AO, Chen YL, Gillespie PM, Kimata JT, Zhan B, Hotez PJ, Bottazzi ME. Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate. Protein Expr Purif. 2022 02; 190:106003. PMID: 34688919.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    10. Bartsch SM, Wedlock PT, O'Shea KJ, Cox SN, Strych U, Nuzzo JB, Ferguson MC, Bottazzi ME, Siegmund SS, Hotez PJ, Lee BY. Lives and Costs Saved by Expanding and Expediting Coronavirus Disease 2019 Vaccination. J Infect Dis. 2021 09 17; 224(6):938-948. PMID: 33954775.
      Citations: 11     Fields:    Translation:HumansCellsPHPublic Health
    11. Rawal K, Sinha R, Abbasi BA, Chaudhary A, Nath SK, Kumari P, Preeti P, Saraf D, Singh S, Mishra K, Gupta P, Mishra A, Sharma T, Gupta S, Singh P, Sood S, Subramani P, Dubey AK, Strych U, Hotez PJ, Bottazzi ME. Identification of vaccine targets in pathogens and design of a vaccine using computational approaches. Sci Rep. 2021 09 02; 11(1):17626. PMID: 34475453.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    12. Pino M, Abid T, Pereira Ribeiro S, Edara VV, Floyd K, Smith JC, Latif MB, Pacheco-Sanchez G, Dutta D, Wang S, Gumber S, Kirejczyk S, Cohen J, Stammen RL, Jean SM, Wood JS, Connor-Stroud F, Pollet J, Chen WH, Wei J, Zhan B, Lee J, Liu Z, Strych U, Shenvi N, Easley K, Weiskopf D, Sette A, Pollara J, Mielke D, Gao H, Eisel N, LaBranche CC, Shen X, Ferrari G, Tomaras GD, Montefiori DC, Sekaly RP, Vanderford TH, Tomai MA, Fox CB, Suthar MS, Kozlowski PA, Hotez PJ, Paiardini M, Bottazzi ME, Kasturi SP. A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates. Sci Immunol. 2021 07 15; 6(61). PMID: 34266981.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    13. Mat Rahim N, Lee H, Strych U, AbuBakar S. Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development. Hum Vaccin Immunother. 2021 10 03; 17(10):3784-3794. PMID: 34106809.
      Citations: 3     Fields:    Translation:HumansCells
    14. Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Brook B, Chen J, Diray-Arce J, Doss-Gollin S, Leon M, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity. bioRxiv. 2021 May 21. PMID: 34031655.
      Citations: 1     
    15. Lee J, Liu Z, Chen WH, Wei J, Kundu R, Adhikari R, Rivera JA, Gillespie PM, Strych U, Zhan B, Hotez PJ, Bottazzi ME. Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain-based vaccine candidate, RBD219-N1C1. Appl Microbiol Biotechnol. 2021 May; 105(10):4153-4165. PMID: 33959781.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    16. Pollet J, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Villar MJ, de Araujo Leao AC, Altieri Rivera J, Momin Z, Gillespie PM, Kimata JT, Strych U, Hotez PJ, Bottazzi ME. SARS-CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice. Hum Vaccin Immunother. 2021 08 03; 17(8):2356-2366. PMID: 33847226.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    17. Chen WH, Wei J, Kundu RT, Adhikari R, Liu Z, Lee J, Versteeg L, Poveda C, Keegan B, Villar MJ, de Araujo Leao AC, Rivera JA, Gillespie PM, Pollet J, Strych U, Zhan B, Hotez PJ, Bottazzi ME. Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate. Biochim Biophys Acta Gen Subj. 2021 06; 1865(6):129893. PMID: 33731300.
      Citations: 10     Fields:    Translation:AnimalsCells
    18. Pollet J, Chen WH, Versteeg L, Keegan B, Zhan B, Wei J, Liu Z, Lee J, Kundu R, Adhikari R, Poveda C, Villar MJ, de Araujo Leao AC, Rivera JA, Momin Z, Gillespie PM, Kimata JT, Strych U, Hotez PJ, Bottazzi ME. SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice. bioRxiv. 2021 Feb 09. PMID: 33173864.
      Citations: 3     
    19. Bartsch SM, O'Shea KJ, Wedlock PT, Strych U, Ferguson MC, Bottazzi ME, Randall SL, Siegmund SS, Cox SN, Hotez PJ, Lee BY. The Benefits of Vaccinating With the First Available COVID-19 Coronavirus Vaccine. Am J Prev Med. 2021 05; 60(5):605-613. PMID: 33632650.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    20. Pollet J, Chen WH, Strych U. Recombinant protein vaccines, a proven approach against coronavirus pandemics. Adv Drug Deliv Rev. 2021 03; 170:71-82. PMID: 33421475.
      Citations: 33     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. Callaghan T, Moghtaderi A, Lueck JA, Hotez P, Strych U, Dor A, Fowler EF, Motta M. Correlates and disparities of intention to vaccinate against COVID-19. Soc Sci Med. 2021 03; 272:113638. PMID: 33414032.
      Citations: 108     Fields:    Translation:HumansPHPublic Health
    22. Chen WH, Tao X, Agrawal AS, Algaissi A, Peng BH, Pollet J, Strych U, Bottazzi ME, Hotez PJ, Lustigman S, Du L, Jiang S, Tseng CK. Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement. Vaccine. 2020 11 03; 38(47):7533-7541. PMID: 33039209.
      Citations: 38     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    23. Liu Z, Kundu R, Damena S, Biter AB, Nyon MP, Chen WH, Zhan B, Strych U, Hotez PJ, Bottazzi ME. A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis. Protein Expr Purif. 2021 01; 177:105750. PMID: 32920041.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    24. Bartsch SM, O'Shea KJ, Ferguson MC, Bottazzi ME, Wedlock PT, Strych U, McKinnell JA, Siegmund SS, Cox SN, Hotez PJ, Lee BY. Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention. Am J Prev Med. 2020 10; 59(4):493-503. PMID: 32778354.
      Citations: 110     Fields:    Translation:HumansCellsPHPublic Health
    25. Chen WH, Tao X, Agrawal A, Algaissi A, Peng BH, Pollet J, Strych U, Bottazzi ME, Hotez PJ, Lustigman S, Du L, Jiang S, Tseng CK. Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Aluminum Hydroxide Induces Protective Immunity and Reduces Immune Enhancement. bioRxiv. 2020 Jul 05. PMID: 32511385.
      Citations:    
    26. Hotez PJ, Corry DB, Strych U, Bottazzi ME. COVID-19 vaccines: neutralizing antibodies and the alum advantage. Nat Rev Immunol. 2020 07; 20(7):399-400. PMID: 32499636.
      Citations: 36     Fields:    Translation:HumansAnimals
    27. Bottazzi ME, Strych U, Hotez PJ, Corry DB. Coronavirus vaccine-associated lung immunopathology-what is the significance? Microbes Infect. 2020 10; 22(9):403-404. PMID: 32599077.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    28. Bartsch SM, O'Shea KJ, Ferguson MC, Bottazzi ME, Cox SN, Strych U, McKinnell JA, Wedlock PT, Siegmund SS, Hotez PJ, Lee BY. How Efficacious Must a COVID-19 Coronavirus Vaccine be to Prevent or Stop an Epidemic by Itself. medRxiv. 2020 May 30. PMID: 32511569.
      Citations:    
    29. Bartsch SM, Stokes-Cawley OJ, Buekens P, Asti L, Bottazzi ME, Strych U, Wedlock PT, Mitgang EA, Meymandi S, Falcon-Lezama JA, Hotez PJ, Lee BY. The potential economic value of a therapeutic Chagas disease vaccine for pregnant women to prevent congenital transmission. Vaccine. 2020 04 03; 38(16):3261-3270. PMID: 32171575.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    30. Chen WH, Strych U, Hotez PJ, Bottazzi ME. The SARS-CoV-2 Vaccine Pipeline: an Overview. Curr Trop Med Rep. 2020; 7(2):61-64. PMID: 32219057.
      Citations: 215     
    31. Chen WH, Nyon MP, Poongavanam MV, Liu Z, Biter AB, Kundu RT, Strych U, Hotez PJ, Bottazzi ME. Process Characterization and Biophysical Analysis for a Yeast-Expressed Phlebotomus papatasi Salivary Protein (PpSP15) as a Leishmania Vaccine Candidate. J Pharm Sci. 2020 05; 109(5):1673-1680. PMID: 32070701.
      Citations: 1     Fields:    Translation:Animals
    32. Versteeg L, Wei J, Liu Z, Keegan B, Fujiwara RT, Jones KM, Asojo O, Strych U, Bottazzi ME, Hotez PJ, Zhan B. Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection. PLoS Negl Trop Dis. 2020 02; 14(2):e0008057. PMID: 32053593.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    33. Frederick J, Hennessy F, Horn U, de la Torre Cortés P, van den Broek M, Strych U, Willson R, Hefer CA, Daran JG, Sewell T, Otten LG, Brady D. The complete genome sequence of the nitrile biocatalyst Rhodocccus rhodochrous ATCC BAA-870. BMC Genomics. 2020 Jan 02; 21(1):3. PMID: 31898479.
      Citations: 3     Fields:    Translation:Cells
    34. Poveda C, Biter AB, Bottazzi ME, Strych U. Establishing Preferred Product Characterization for the Evaluation of RNA Vaccine Antigens. Vaccines (Basel). 2019 Sep 27; 7(4). PMID: 31569760.
      Citations: 8     
    35. Biter AB, Pollet J, Chen WH, Strych U, Hotez PJ, Bottazzi ME. A method to probe protein structure from UV absorbance spectra. Anal Biochem. 2019 12 15; 587:113450. PMID: 31550438.
      Citations:    Fields:    Translation:Cells
    36. Bartsch SM, Bottazzi ME, Asti L, Strych U, Meymandi S, Falcón-Lezama JA, Randall S, Hotez PJ, Lee BY. Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients. Vaccine. 2019 06 19; 37(28):3704-3714. PMID: 31104883.
      Citations: 5     Fields:    Translation:HumansAnimalsPHPublic Health
    37. Gunter SM, Versteeg L, Jones KM, Keegan BP, Strych U, Bottazzi ME, Hotez PJ, Brown EL. Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production. Parasite Immunol. 2018 Nov; 40(11):e12585. PMID: 30132929.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    38. Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ. Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen. Vaccine. 2018 03 27; 36(14):1853-1862. PMID: 29496347.
      Citations: 34     Fields:    Translation:AnimalsCells
    39. Biter AB, Weltje S, Hudspeth EM, Seid CA, McAtee CP, Chen WH, Pollet JB, Strych U, Hotez PJ, Bottazzi ME. Characterization and Stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a Candidate Antigen for a Therapeutic Vaccine Against Chagas Disease. J Pharm Sci. 2018 05; 107(5):1468-1473. PMID: 29274820.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    40. Wei J, Versteeg L, Liu Z, Keegan B, Gazzinelli-Guimarães AC, Fujiwara RT, Briggs N, Jones KM, Strych U, Beaumier CM, Bottazzi ME, Hotez PJ, Zhan B. Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response. PLoS Negl Trop Dis. 2017 Jul; 11(7):e0005769. PMID: 28708895.
      Citations: 14     Fields:    Translation:AnimalsCellsPHPublic Health
    41. Gunter SM, Jones KM, Seid CA, Essigmann HT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Brown EL. Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis. J Parasitol. 2017 10; 103(5):579-583. PMID: 28581897.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    42. Chen WH, Chag SM, Poongavanam MV, Biter AB, Ewere EA, Rezende W, Seid CA, Hudspeth EM, Pollet J, McAtee CP, Strych U, Bottazzi ME, Hotez PJ. Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate. J Pharm Sci. 2017 08; 106(8):1961-1970. PMID: 28456726.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    43. Pollet J, Versteeg L, Rezende W, Strych U, Gusovsky F, Hotez PJ, Bottazzi ME. A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations. Vaccine. 2017 03 07; 35(10):1410-1416. PMID: 28190745.
      Citations:    Fields:    Translation:Humans
    44. Seid CA, Jones KM, Pollet J, Keegan B, Hudspeth E, Hammond M, Wei J, McAtee CP, Versteeg L, Gutierrez A, Liu Z, Zhan B, Respress JL, Strych U, Bottazzi ME, Hotez PJ. Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease. Hum Vaccin Immunother. 2017 03 04; 13(3):621-633. PMID: 27737611.
      Citations: 15     Fields:    Translation:AnimalsCells
    45. Wei J, Damania A, Gao X, Liu Z, Mejia R, Mitreva M, Strych U, Bottazzi ME, Hotez PJ, Zhan B. The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates. Parasit Vectors. 2016 Sep 27; 9(1):518. PMID: 27677574.
      Citations: 10     Fields:    
    46. Lee HY, Nyon MP, Strych U. Vaccine Development Against Middle East Respiratory Syndrome. Curr Trop Med Rep. 2016; 3(3):80-86. PMID: 32226714.
      Citations:    
    47. Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Human anthelminthic vaccines: Rationale and challenges. Vaccine. 2016 06 24; 34(30):3549-55. PMID: 27171753.
      Citations: 18     Fields:    Translation:Humans
    48. Chen H, Hagström AE, Kim J, Garvey G, Paterson A, Ruiz-Ruiz F, Raja B, Strych U, Rito-Palomares M, Kourentzi K, Conrad JC, Atmar RL, Willson RC. Flotation Immunoassay: Masking the Signal from Free Reporters in Sandwich Immunoassays. Sci Rep. 2016 Apr 14; 6:24297. PMID: 27075635.
      Citations: 4     Fields:    
    49. Hotez PJ, Beaumier CM, Gillespie PM, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. 2016 06 03; 34(26):3001-3005. PMID: 27040400.
      Citations: 18     Fields:    Translation:HumansAnimals
    50. Merrifield M, Hotez PJ, Beaumier CM, Gillespie P, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent human schistosomiasis. Vaccine. 2016 06 03; 34(26):2988-2991. PMID: 27036511.
      Citations: 45     Fields:    Translation:HumansAnimals
    51. Beaumier CM, Gillespie PM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for Chagas disease. Vaccine. 2016 06 03; 34(26):2996-3000. PMID: 27026146.
      Citations: 25     Fields:    Translation:Humans
    52. Gillespie PM, Beaumier CM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for leishmaniasis. Vaccine. 2016 06 03; 34(26):2992-2995. PMID: 26973063.
      Citations: 59     Fields:    Translation:HumansAnimals
    53. Hudspeth EM, Wang Q, Seid CA, Hammond M, Wei J, Liu Z, Zhan B, Pollet J, Heffernan MJ, McAtee CP, Engler DA, Matsunami RK, Strych U, Asojo OA, Hotez PJ, Bottazzi ME. Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties. Hum Vaccin Immunother. 2016 07 02; 12(7):1707-20. PMID: 26839079.
      Citations: 5     Fields:    Translation:AnimalsCells
    54. Adhikari M, Strych U, Kim J, Goux H, Dhamane S, Poongavanam MV, Hagström AE, Kourentzi K, Conrad JC, Willson RC. Aptamer-Phage Reporters for Ultrasensitive Lateral Flow Assays. Anal Chem. 2015 Dec 01; 87(23):11660-5. PMID: 26456715.
      Citations: 8     Fields:    Translation:Cells
    55. Hotez PJ, Bottazzi ME, Strych U. New Vaccines for the World's Poorest People. Annu Rev Med. 2016; 67:405-17. PMID: 26356803.
      Citations: 20     Fields:    Translation:Humans
    56. Hagström AE, Garvey G, Paterson AS, Dhamane S, Adhikari M, Estes MK, Strych U, Kourentzi K, Atmar RL, Willson RC. Sensitive detection of norovirus using phage nanoparticle reporters in lateral-flow assay. PLoS One. 2015; 10(5):e0126571. PMID: 25978622.
      Citations: 15     Fields:    Translation:HumansCells
    57. Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003575. PMID: 25880767.
      Citations: 42     Fields:    Translation:HumansAnimalsPHPublic Health
    58. Kolhatkar AG, Dannongoda C, Kourentzi K, Jamison AC, Nekrashevich I, Kar A, Cacao E, Strych U, Rusakova I, Martirosyan KS, Litvinov D, Lee TR, Willson RC. Enzymatic synthesis of magnetic nanoparticles. Int J Mol Sci. 2015 Apr 03; 16(4):7535-50. PMID: 25854425.
      Citations:    Fields:    
    59. Kim J, Adhikari M, Dhamane S, Hagström AE, Kourentzi K, Strych U, Willson RC, Conrad JC. Detection of viruses by counting single fluorescent genetically biotinylated reporter immunophage using a lateral flow assay. ACS Appl Mater Interfaces. 2015 Feb 04; 7(4):2891-8. PMID: 25581289.
      Citations: 4     Fields:    Translation:Cells
    60. Li Y, Mortuza R, Milligan DL, Tran SL, Strych U, Cook GM, Krause KL. Investigation of the essentiality of glutamate racemase in Mycobacterium smegmatis. J Bacteriol. 2014 Dec; 196(24):4239-44. PMID: 25246478.
      Citations: 6     Fields:    Translation:Cells
    61. Qi J, Zeng J, Zhao F, Lin SH, Raja B, Strych U, Willson RC, Shih WC. Label-free, in situ SERS monitoring of individual DNA hybridization in microfluidics. Nanoscale. 2014 Aug 07; 6(15):8521-6. PMID: 24953169.
      Citations: 16     Fields:    Translation:HumansCells
    62. Zhao F, Zeng J, Parvez Arnob MM, Sun P, Qi J, Motwani P, Gheewala M, Li CH, Paterson A, Strych U, Raja B, Willson RC, Wolfe JC, Lee TR, Shih WC. Monolithic NPG nanoparticles with large surface area, tunable plasmonics, and high-density internal hot-spots. Nanoscale. 2014 Jul 21; 6(14):8199-207. PMID: 24926835.
      Citations: 12     Fields:    
    63. Litvinov J, Hagström AE, Lopez Y, Adhikari M, Kourentzi K, Strych U, Monzon FA, Foster W, Cagle PT, Willson RC. Ultrasensitive immuno-detection using viral nanoparticles with modular assembly using genetically-directed biotinylation. Biotechnol Lett. 2014 Sep; 36(9):1863-8. PMID: 24930095.
      Citations: 5     Fields:    Translation:HumansCells
    64. Adhikari M, Dhamane S, Hagström AE, Garvey G, Chen WH, Kourentzi K, Strych U, Willson RC. Functionalized viral nanoparticles as ultrasensitive reporters in lateral-flow assays. Analyst. 2013 Oct 07; 138(19):5584-7. PMID: 23905160.
      Citations: 10     Fields:    Translation:HumansCells
    65. Kanakaraj I, Chen WH, Poongavanam M, Dhamane S, Stagg LJ, Ladbury JE, Kourentzi K, Strych U, Willson RC. Biophysical characterization of VEGF-aHt DNA aptamer interactions. Int J Biol Macromol. 2013 Jun; 57:69-75. PMID: 23470436.
      Citations: 2     Fields:    Translation:HumansAnimals
    66. Pollet J, Strych U, Willson RC. A peroxidase-active aptazyme as an isothermally amplifiable label in an aptazyme-linked oligonucleotide assay for low-picomolar IgE detection. Analyst. 2012 Dec 21; 137(24):5710-2. PMID: 23103946.
      Citations: 3     Fields:    Translation:Cells
    67. Vu BV, Anthony KL, Strych U, Willson RC. Recovery of small DNA fragments from serum using compaction precipitation. PLoS One. 2012; 7(12):e51863. PMID: 23284792.
      Citations: 1     Fields:    Translation:HumansCells
    68. Gijavanekar C, Drabek R, Soni M, Jackson GW, Strych U, Fox GE, Fofanov Y, Willson RC. Detection and typing of viruses using broadly sensitive cocktail-PCR and mass spectrometric cataloging: demonstration with dengue virus. J Mol Diagn. 2012 Jul; 14(4):402-7. PMID: 22579629.
      Citations: 1     Fields:    Translation:Cells
    69. Willson Richard C, Ulrich Strych, Vu Binh V. Particulate labels. 2012.
    70. Gijavanekar C, Strych U, Fofanov Y, Fox GE, Willson RC. Rare target enrichment for ultrasensitive PCR detection using cot-rehybridization and duplex-specific nuclease. Anal Biochem. 2012 Feb 01; 421(1):81-5. PMID: 22155054.
      Citations: 5     Fields:    Translation:AnimalsCells
    71. Anthony KG, Strych U, Yeung KR, Shoen CS, Perez O, Krause KL, Cynamon MH, Aristoff PA, Koski RA. New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis. PLoS One. 2011; 6(5):e20374. PMID: 21637807.
      Citations: 17     Fields:    Translation:HumansCells
    72. Im H, Sharpe ML, Strych U, Davlieva M, Krause KL. The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design. BMC Microbiol. 2011 May 25; 11:116. PMID: 21612658.
      Citations: 13     Fields:    Translation:HumansCells
    73. Liu Y, Stepanov VG, Strych U, Willson RC, Jackson GW, Fox GE. DNAzyme-mediated recovery of small recombinant RNAs from a 5S rRNA-derived chimera expressed in Escherichia coli. BMC Biotechnol. 2010 Dec 06; 10:85. PMID: 21134283.
      Citations: 11     Fields:    Translation:Cells
    74. George Jackson, Roger McNichols, Ulrich Strych, George E. Fox, Victor G. Stepanov, Yamei Liu. Functional nucleic acids and methods. 2010.
    75. Strych, U. and Willson, R.C. Manual of Industrial Microbiology and Biotechnology, Editors: Richard H Baltz, Julian Davies, Arnold L Demain. Purification and Characterization of Proteins (Ch.52). 2010.
    76. George Jackson, Stephen Navran, Ulrich Strych. Biomimetic nucleic acids. 2009.
    77. Couñago RM, Davlieva M, Strych U, Hill RE, Krause KL. Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames). BMC Struct Biol. 2009 Aug 20; 9:53. PMID: 19695097.
      Citations: 15     Fields:    Translation:Cells
    78. Zhang X, Potty AS, Jackson GW, Stepanov V, Tang A, Liu Y, Kourentzi K, Strych U, Fox GE, Willson RC. Engineered 5S ribosomal RNAs displaying aptamers recognizing vascular endothelial growth factor and malachite green. J Mol Recognit. 2009 Mar-Apr; 22(2):154-61. PMID: 19195013.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    79. Milligan DL, Tran SL, Strych U, Cook GM, Krause KL. The alanine racemase of Mycobacterium smegmatis is essential for growth in the absence of D-alanine. J Bacteriol. 2007 Nov; 189(22):8381-6. PMID: 17827284.
      Citations: 16     Fields:    Translation:Cells
    80. Strych U, Davlieva M, Longtin JP, Murphy EL, Im H, Benedik MJ, Krause KL. Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae. BMC Microbiol. 2007 May 17; 7:40. PMID: 17509154.
      Citations: 8     Fields:    Translation:Cells
    81. Michael Benedik, James M Briggs, Myoung Goo Kim, Harold Kohn, Kurt L Krause, Ulrich Strych. Compositions having antimycrobial activity including a hydroxamate or a hydroxamate and a hydroxylamine. 2005.
    82. LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H, Krause KL. The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry. 2005 Feb 08; 44(5):1471-81. PMID: 15683232.
      Citations: 29     Fields:    Translation:Cells
    83. LeMagueres P, Im H, Dvorak A, Strych U, Benedik M, Krause KL. Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. Biochemistry. 2003 Dec 23; 42(50):14752-61. PMID: 14674749.
      Citations: 17     Fields:    Translation:Cells
    84. Kim MG, Strych U, Krause K, Benedik M, Kohn H. N(2)-substituted D,L-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors. J Antibiot (Tokyo). 2003 Feb; 56(2):160-8. PMID: 12715876.
      Citations: 7     Fields:    Translation:Cells
    85. Myoung Goo Kim; Ulrich Strych; Kurt Krause; Michael Benedik; Harold Kohn. Evaluation of amino-substituted heterocyclic derivatives as alanine racemase inhibitors. Medicinal Chemistry Research. 2003; 3(12):130-138. View Publication.
    86. Strych U, Benedik MJ. Mutant analysis shows that alanine racemases from Pseudomonas aeruginosa and Escherichia coli are dimeric. J Bacteriol. 2002 Aug; 184(15):4321-5. PMID: 12107154.
      Citations: 14     Fields:    Translation:Cells
    87. Strych U, Penland RL, Jimenez M, Krause KL, Benedik MJ. Characterization of the alanine racemases from two mycobacteria. FEMS Microbiol Lett. 2001 Mar 15; 196(2):93-8. PMID: 11267762.
      Citations: 32     Fields:    Translation:Cells
    88. Strych U, Huang HC, Krause KL, Benedik MJ. Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1. Curr Microbiol. 2000 Oct; 41(4):290-4. PMID: 10977898.
      Citations: 23     Fields:    Translation:Cells
    89. Strych U, Dai W, Benedik MJ. The NucE and NucD lysis proteins are not essential for secretion of the Serratia marcescens extracellular nuclease. Microbiology (Reading). 1999 May; 145 ( Pt 5):1209-1216. PMID: 10376837.
      Citations: 1     Fields:    Translation:Cells
    90. Benedik MJ, Strych U. Serratia marcescens and its extracellular nuclease. FEMS Microbiol Lett. 1998 Aug 01; 165(1):1-13. PMID: 9711834.
      Citations: 16     Fields:    Translation:Cells
    91. Strych U, Wohlfarth S, Winkler UK. Orotidine-5'-monophosphate decarboxylase from Pseudomonas aeruginosa PAO1: cloning, overexpression, and enzyme characterization. Curr Microbiol. 1994 Dec; 29(6):353-9. PMID: 7765522.
      Citations: 2     Fields:    Translation:Cells
    STRYCH's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (381)
    Explore
    _
    Co-Authors (17)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _