JOSEPH SPINNER

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6651 MAIN STREET
Houston, TX 77030
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    Collapse Biography 
    Collapse awards and honors
    2013 - 2014Resident of the Year, Texas Children's Hospital
    2017 - 2018Dan G. McNamara Pediatric Cardiology Fellow of the Year, Texas Children's Hospital
    2019Top Abstract - American Society for Artificial Internal Organs 65th Annual Conference
    2018Best Abstract – Heart Transplant: International Pediatric VAD and Heart Failure Summit 2018
    2015 - 2018Adeline B. Landa Endowed Fellow , Texas Children's Hospital

    Collapse Research 
    Collapse research activities and funding
    W81XWH-18-1-0557     (Dr. Joseph Spinner)Sep 1, 2018 - Feb 28, 2022
    Department of Defense
    Composition, Function, and Role of the Intestinal Microbiome in Pediatric Heart Failure and Heart Transplantation
    Role Description: The primary objective is to characterize and determine the role of the intestinal microbiome in children who have undergone heart transplantation. We hypothesize that dysbiosis increases the risk of post-transplant complications
    Role: Principal Investigator

         (Dr. Joseph Spinner)Jul 19, 2019 - Dec 31, 2020
    Texas Children’s Hospital Heart Center Innovation Award
    Novel Noninvasive Detection of Cardiac Allograft Rejection after Pediatric Heart Transplantation
    Role Description: Goal is detect the presence of allogeneic chimerism in the serum and plasma of patients after heart transplant to detect or predict cardiac allograft rejection.
    Role: Principal Investigator

         (Dr. David Rosenthal)Jan 1, 2021 - Dec 31, 2023
    Enduring Hearts and Additional Ventures
    Can HLA data be used to support Precision Medicine in Pediatric Heart Transplantation? An exploratory analysis
    Role Description: Goal is to analyze the impact of HLA donor/recipient matching and pre-transplant HLA antibodies on survival and adverse events. Goal is also to develop a decision support tool for predicting the results of a virtual crossmatch at the time of a donor offer.

    AHA 824138     (Dr. James Martin)Jul 1, 2021 - Jun 30, 2024
    American Heart Association and Enduring Hearts
    Early Detection of Cardiac Allograft Vasculopathy in Post-Transplant Hearts via Single-Cell Genomics
    Role Description: Goal is to identify coronary allograft vasculopathy at early stages using single-cell RNA sequencing (scRNA-seq) to study heart tissue obtained from children with heart disease which may allow for early detection and subsequent treatment.
    Role: Co-Investigator

         (Dr. Joseph Spinner)Jul 1, 2022 - Jun 30, 2024
    Enduring Hearts
    Non-HLA Antibodies in Pediatric Heart Transplantation
    Role Description: Investigation of the presence and role of non-HLA antibodies in pediatric heart transplantation rejection and coronary allograft vasculopathy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Puri K, Tunuguntla HP, Hensch LA, Loh J, Hui SK, Razavi A, Tume SC, Humlicek TJ, Denfield SW, Spinner JA, Choudhry S, Price JF, Dreyer WJ, Adachi I, Teruya J. Bivalirudin or Unfractionated Heparin for Anticoagulation in Pediatric Patients on Continuous Flow Ventricular Assist Device Support: Single-Center Retrospective Cohort Study. Pediatr Crit Care Med. 2022 Jun 10. PMID: 35687091.
      Citations:    Fields:    
    2. Godown J, Fountain D, Bansal N, Ameduri R, Anderson S, Beasley G, Burstein D, Knecht K, Molina K, Pye S, Richmond M, Spinner JA, Watanabe K, West S, Reinhardt Z, Scheel J, Urschel S, Villa C, Hollander SA. Heart Transplantation in Children With Down Syndrome. J Am Heart Assoc. 2022 05 17; 11(10):e024883. PMID: 35574952.
      Citations: 1     Fields:    Translation:Humans
    3. Puri K, Denfield SW, Adachi I, Dreyer WJ, Price JF, Spinner JA, Choudhry S, Brackett J, Santucci G, Rainusso NC, Tunuguntla HP. Ventricular assist device support for children with chemotherapy-induced cardiomyopathy and advanced heart failure: Perspectives gained from a single-center experience. Pediatr Transplant. 2022 08; 26(5):e14286. PMID: 35474630.
      Citations:    Fields:    Translation:Humans
    4. Lahiri S, Choudhry S, Denfield SW, Price JF, Cabrera AG, Dreyer WJ, Spinner JA, Loar RW, Elias B, McMullen J, Qureshi AM, Adachi I, Tunuguntla HP. Does Cardiac Catheterization Facilitate Hemodynamic Optimization of Pediatric Patients on Continuous-Flow Ventricular Assist Devices? ASAIO J. 2022 04 01; 68(4):584-591. PMID: 35349525.
      Citations:    Fields:    Translation:Humans
    5. Alali A, Acosta S, Ahmed M, Spinner J, Akcan-Arikan A, Morris SA, Jain PN. Postoperative physiological parameters associated with severe acute kidney injury after pediatric heart transplant. Pediatr Transplant. 2022 08; 26(5):e14267. PMID: 35279933.
      Citations:    Fields:    Translation:Humans
    6. Hope KD, Spinner JA. Right-Sided Heart Failure and Cor Pulmonale in the Pediatric Patient. Pediatr Rev. 2022 Mar 01; 43(3):188-190. PMID: 35229108.
      Citations:    Fields:    Translation:Humans
    7. Lay E, Azamian MS, Denfield SW, Dreyer W, Spinner JA, Kearney D, Zhang L, Worley KC, Bi W, Lalani SR. LMOD2-related dilated cardiomyopathy presenting in late infancy. Am J Med Genet A. 2022 06; 188(6):1858-1862. PMID: 35188328.
      Citations:    Fields:    Translation:HumansAnimalsCells
    8. Spinner JA, Denfield SW. Immunosuppressant Drugs and Their Effects on Children Undergoing Solid Organ Transplant. Pediatr Rev. 2022 Feb 01; 43(2):71-86. PMID: 35102401.
      Citations:    Fields:    Translation:Humans
    9. Puri K, Adachi I, Bocchini CE, Spinner JA, Denfield SW, Sisley S, Elias BA, Jimenez-Gomez A, Price JF, Dreyer WJ, Choudhry S, Tunuguntla HP. Trends in Body Mass Index and Association With Outcomes in Pediatric Patients on Continuous Flow Ventricular Assist Device Support. ASAIO J. 2022 09 01; 68(9):1182-1190. PMID: 34967787.
      Citations:    Fields:    
    10. Day P, Hope K, Puri K, Spinner J, Choudhry S, Tunuguntla H, Price J, Dreyer W, Denfield S. Outcomes following use of pediatric and young adult donor hearts with bicuspid aortic valves: A single-center case series. Pediatr Transplant. 2022 05; 26(3):e14212. PMID: 34921483.
      Citations:    Fields:    Translation:Humans
    11. Spinner JA, Julien CL, Olayinka L, Dreyer WJ, Bocchini CE, Munoz FM, Devaraj S. SARS-CoV-2 anti-spike antibodies after vaccination in pediatric heart transplantation: A first report. J Heart Lung Transplant. 2022 02; 41(2):133-136. PMID: 34911654.
      Citations: 3     Fields:    Translation:HumansCells
    12. Puri K, Spinner JA, Powers JM, Denfield SW, Tunuguntla HP, Choudhry S, Dreyer WJ, Price JF. Poor efficacy of oral iron replacement therapy in pediatric patients with heart failure. Cardiol Young. 2022 Aug; 32(8):1302-1309. PMID: 34629125.
      Citations:    Fields:    
    13. Valencia Deray KG, Hosek KE, Chilukuri D, Dunson JR, Spielberg DR, Swartz SJ, Spinner JA, Leung DH, Moulton EA, Munoz FM, Demmler-Harrison GJ, Bocchini CE. Epidemiology and long-term outcomes of cytomegalovirus DNAemia and disease in pediatric solid organ transplant recipients. Am J Transplant. 2022 01; 22(1):187-198. PMID: 34467658.
      Citations:    Fields:    Translation:HumansCells
    14. Spinner JA, Tunuguntla HP, Tume SC, Elias BA, Mcmullen J, John R, Choudhry S, Price JF, Denfield SW, Dreyer WJ, Adachi I. "Compassionate" Cases of the Jarvik 2015 Ventricular Assist Device. ASAIO J. 2021 09 01; 67(9):1036-1043. PMID: 33470634.
      Citations: 1     Fields:    Translation:Humans
    15. Choudhry S, Dreyer WJ, Hope KD, Wang Y, Spinner JA, Tunuguntla HP, Cabrera AG, Price JF, Denfield SW. Pediatric heart-liver transplant outcomes in the United States: A 25-year National Cohort Study. Pediatr Transplant. 2021 Nov; 25(7):e14066. PMID: 34120386.
      Citations:    Fields:    Translation:Humans
    16. Spinner JA, Denfield SW, Puri K, Morris SA, Costello JM, Moffett BS, Wang Y, Shekerdemian LS, Tunuguntla HP, Price JF, Heinle JS, Adachi I, Dreyer WJ, Cabrera AG. Hospital outcomes for pediatric heart transplant recipients undergoing tracheostomy: A multi-institutional analysis. Pediatr Transplant. 2021 May; 25(3):e13904. PMID: 33179431.
      Citations:    Fields:    Translation:Humans
    17. Stidham J, Feingold B, Almond CS, Burstein DS, Krack P, Price JF, Schumacher KR, Spinner JA, Rosenthal DN, Lorts A, Godown J. Establishing Baseline Metrics of Heart Failure Medication Use in Children: A Collaborative Effort from the ACTION Network. Pediatr Cardiol. 2021 Feb; 42(2):315-323. PMID: 33044586.
      Citations:    Fields:    Translation:Humans
    18. Spinner JA, Morris SA, Nandi D, Costarino AT, Marino BS, Rossano JW, Shamszad P. Necrotizing Enterocolitis and Associated Mortality in Neonates With Congenital Heart Disease: A Multi-Institutional Study. Pediatr Crit Care Med. 2020 03; 21(3):228-234. PMID: 31568264.
      Citations: 11     Fields:    Translation:Humans
    19. Spinner JA, Bocchini CE, Luna RA, Thapa S, Balderas MA, Denfield SW, Dreyer WJ, Nagy-Szakal D, Ihekweazu FD, Versalovic J, Savidge T, Kellermayer R. Fecal microbiota transplantation in a toddler after heart transplant was a safe and effective treatment for recurrent Clostridiodes difficile infection: A case report. Pediatr Transplant. 2020 02; 24(1):e13598. PMID: 31617299.
      Citations: 4     Fields:    Translation:HumansCells
    20. Puri K, Price JF, Spinner JA, Powers JM, Denfield SW, Cabrera AG, Tunuguntla HP, Dreyer WJ, Shah MD. Iron Deficiency Is Associated with Adverse Outcomes in Pediatric Heart Failure. J Pediatr. 2020 01; 216:58-66.e1. PMID: 31610927.
      Citations: 3     Fields:    Translation:Humans
    21. Adachi I, Spinner JA, Tunuguntla HP, Elias BA, Heinle JS. The miniaturized pediatric continuous-flow device: A successful bridge to heart transplant. J Heart Lung Transplant. 2019 07; 38(7):789-793. PMID: 31109819.
      Citations: 2     Fields:    Translation:Humans
    22. Chen PC, Spinner JA, Heinle JS. Large right ventricular sinusoids in an infant with aorta-left ventricular tunnel and proximal right coronary artery atresia. Cardiol Young. 2018 Jul; 28(7):978-980. PMID: 29656724.
      Citations:    Fields:    Translation:Humans
    23. Spinner JA, Noel CV, Denfield SW, Krishnamurthy R, Jeewa A, Dreyer WJ, Maskatia SA. Association of Late Gadolinium Enhancement and Degree of Left Ventricular Hypertrophy Assessed on Cardiac Magnetic Resonance Imaging With Ventricular Tachycardia in Children With Hypertrophic Cardiomyopathy. Am J Cardiol. 2016 Apr 15; 117(8):1342-8. PMID: 26892450.
      Citations: 11     Fields:    Translation:Humans
    24. Grimm JC, Magruder JT, Do N, Spinner JA, Dungan SP, Kilic A, Patel N, Nelson KL, Jacobs ML, Cameron DE, Vricella LA. Modified Model for End-Stage Liver Disease eXcluding INR (MELD-XI) Score Predicts Early Death After Pediatric Heart Transplantation. Ann Thorac Surg. 2016 Feb; 101(2):730-5. PMID: 26347119.
      Citations: 6     Fields:    Translation:Humans
    25. Lui C, Grimm JC, Magruder JT, Dungan SP, Spinner JA, Do N, Nelson KL, Cameron DE, Vricella LA, Jacobs ML. The Effect of Institutional Volume on Complications and Their Impact on Mortality After Pediatric Heart Transplantation. Ann Thorac Surg. 2015 Oct; 100(4):1423-31. PMID: 26298167.
      Citations: 3     Fields:    Translation:Humans
    26. Maskatia SA, Morris SA, Spinner JA, Krishnamurthy R, Altman CA. Echocardiographic Parameters of Right Ventricular Diastolic Function in Repaired Tetralogy of Fallot Are Associated with Important Findings on Magnetic Resonance Imaging. Congenit Heart Dis. 2015 May-Jun; 10(3):E113-22. PMID: 25916551.
      Citations: 3     Fields:    Translation:Humans
    27. Maskatia SA, Spinner JA, Nutting AC, Slesnick TC, Krishnamurthy R, Morris SA. Impact of obesity on ventricular size and function in children, adolescents and adults with Tetralogy of Fallot after initial repair. Am J Cardiol. 2013 Aug 15; 112(4):594-8. PMID: 23677064.
      Citations: 7     Fields:    Translation:Humans
    28. Maskatia SA, Spinner JA, Morris SA, Petit CJ, Krishnamurthy R, Nutting AC. Effect of branch pulmonary artery stenosis on right ventricular volume overload in patients with tetralogy of fallot after initial surgical repair. Am J Cardiol. 2013 May 01; 111(9):1355-60. PMID: 23411101.
      Citations: 3     Fields:    Translation:Humans
    29. Maskatia SA, Decker JA, Spinner JA, Kim JJ, Price JF, Jefferies JL, Dreyer WJ, Smith EO, Rossano JW, Denfield SW. Restrictive physiology is associated with poor outcomes in children with hypertrophic cardiomyopathy. Pediatr Cardiol. 2012 Jan; 33(1):141-9. PMID: 21892651.
      Citations: 17     Fields:    Translation:Humans
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