TZU-CHIAO LU

TitleInstructor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
AddressOne Baylor Plaza
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    Other Positions
    TitleInstructor
    InstitutionBaylor College of Medicine
    DepartmentHuffington Center on Aging
    DivisionHuffington Ctr on Aging


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Huang CH, Hsu CH, Tseng BY, Chang MC, Lai YC, Lin CY, Hsiao CK, Lu TP, Yu SL, Hsieh ST, Chen WJ. Relationships Between Alcohol Intake and Mitochondrial DNA Methylation in the Human Prefrontal Cortex and Nucleus Accumbens. Neuropathol Appl Neurobiol. 2025 10; 51(5):e70035. PMID: 40862369.
      Citations:    Fields:    Translation:HumansCells
    2. Chen CH, Chen IC, Hsu CL, Lu TP, Wang MY, Tsai LW, Huang CS, Lu YS, Lin CH. Characterization of the tumor immune microenvironment in pregnancy-associated breast cancer through multiplex immunohistochemistry and transcriptome analyses. Breast Cancer Res. 2025 Aug 26; 27(1):154. PMID: 40859352; PMCID: PMC12382146.
      Citations:    Fields:    Translation:HumansCells
    3. Lu YA, Chen CJ, Lu TP, Wang JY, Huang DT. Genetic susceptibility associated with hospitalization due to respiratory syncytial virus in a group of Taiwanese children: a preliminary study. Front Pediatr. 2025; 13:1473448. PMID: 40873739; PMCID: PMC12378803.
      Citations:    
    4. Park YJ, Lu TC, Jackson T, Goodman LD, Ran L, Chen J, Liang CY, Harrison E, Ko C, Chen X, Wang B, Hsu AL, Ochoa E, Bieniek KF, Yamamoto S, Zhu Y, Zheng H, Qi Y, Bellen HJ, Li H. Distinct systemic impacts of A?42 and Tau revealed by whole-organism snRNA-seq. Neuron. 2025 Jul 09; 113(13):2065-2082.e8. PMID: 40381615; PMCID: PMC12245608.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Huang CC, Lu TP, Wang YJ, Chen BF, Yang HT, Chang WP, Tseng LM. Identifying breast cancer risk factors and evaluating biennial mammography screening efficacy using big data analysis in Taiwan. Sci Rep. 2025 May 09; 15(1):16250. PMID: 40346112; PMCID: PMC12064733.
      Citations:    Fields:    Translation:HumansPHPublic Health
    6. Chen PH, Tsai TM, Lu TP, Lu HH, Pamart D, Kotronoulas A, Herzog M, Micallef JV, Hsu HH, Chen JS. Accurate Diagnosis of High-Risk Pulmonary Nodules Using a Non-Invasive Epigenetic Biomarker Test. Cancers (Basel). 2025 Mar 07; 17(6). PMID: 40149253; PMCID: PMC11940740.
      Citations: 1     
    7. Feng YA, Chen WJ, Lin MC, Hsu JS, Cheng CF, Liu CM, Hwu HG, Huang YT, Lu TP, Wang SH. Paternal age, de novo mutation, and age at onset among co-affected schizophrenia sib-pairs: whole-genome sequencing in multiplex families. Mol Psychiatry. 2025 Aug; 30(8):3560-3567. PMID: 40038545.
      Citations: 1     Fields:    Translation:Humans
    8. Hsieh MS, Wu PH, Chiu KC, Liao SH, Chen CS, Hsiao TH, Chen YM, Hu SY, How CK, Chattopadhyay A, Lu TP. Population-specific genetic-risk scores enable improved prediction of mortality within 28?days of sepsis onset: a retrospective Taiwanese cohort study. J Intensive Care. 2025 Feb 26; 13(1):11. PMID: 40011956; PMCID: PMC11863615.
      Citations:    
    9. Chen PH, Chen C, Lu CW, Lu TP, Lee YH, Hsieh MS, Hsu HH, Chen JS. Correction: Tumor Spread Through Air Spaces Predicts Survival in Resected Pulmonary Lymphoepithelial Carcinoma. Ann Surg Oncol. 2025 Feb; 32(2):896. PMID: 39546108.
      Citations:    Fields:    
    10. Chattopadhyay A, Wu YT, Chan HC, Kang YT, Chiang YC, Chiang CJ, Lee WC, Lu TP. Predicting Survival Outcomes for Patients with Ovarian Cancer Using National Cancer Registry Data from Taiwan: A Retrospective Cohort Study. Womens Health Rep (New Rochelle). 2025; 6(1):90-101. PMID: 39882147; PMCID: PMC11773178.
      Citations:    
    11. Fan HY, Tsai MC, Lai CJ, Yeh CL, Hsu HY, Lai PJ, Hsu HC, Su TC, Lin HJ, Lin YF, Lu TP, Chien KL. Genetic Variants in Severe Hypertriglyceridemia Among Taiwanese Participants - Insights From Genome-Wide Association and Whole-Exome Sequencing Analyses. Circ J. 2025 Feb 25; 89(3):331-339. PMID: 39662927.
      Citations:    Fields:    Translation:Humans
    12. Chen PH, Chen C, Lu CW, Lu TP, Lee YH, Hsieh MS, Hsu HH, Chen JS. ASO Author Reflections: Tumor Spread Through Air Spaces Predicts Survival in Resected Pulmonary Lymphoepithelial Carcinoma. Ann Surg Oncol. 2025 Apr; 32(4):2698-2699. PMID: 39616296.
      Citations:    Fields:    
    13. Chen PH, Chen C, Lu CW, Lu TP, Lee YH, Hsieh MS, Hsu HH, Chen JS. Tumor Spread Through Air Spaces Predicts Survival in Resected Pulmonary Lymphoepithelial Carcinoma. Ann Surg Oncol. 2025 Apr; 32(4):2675-2686. PMID: 39495361.
      Citations: 1     Fields:    Translation:Humans
    14. Chen HL, Chiang HY, Chang DR, Cheng CF, Wang CCN, Lu TP, Lee CY, Chattopadhyay A, Lin YT, Lin CC, Yu PT, Huang CF, Lin CH, Yeh HC, Ting IW, Tsai HK, Chuang EY, Tin A, Tsai FJ, Kuo CC. Discovery and prioritization of genetic determinants of kidney function in 297,355 individuals from Taiwan and Japan. Nat Commun. 2024 10 29; 15(1):9317. PMID: 39472450; PMCID: PMC11522641.
      Citations: 4     Fields:    Translation:Humans
    15. Jen CW, Chan HC, Chiang CJ, Lee WC, Lu TP, Cheng SH. Evaluating the Efficacy of Different Treatment Intensities in Nasopharyngeal Carcinoma Patients: A Nationwide Cancer Registry-Based Study. Ann Surg Oncol. 2024 Dec; 31(13):9125-9133. PMID: 39240395.
      Citations: 1     Fields:    Translation:Humans
    16. Chen CS, Yuan TH, Lu TP, Lee HY, Chen YH, Lai LC, Tsai MH, Chuang EY, Chan CC. Exposure-associated DNA methylation among people exposed to multiple industrial pollutants. Clin Epigenetics. 2024 Aug 20; 16(1):111. PMID: 39164771; PMCID: PMC11337639.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    17. Ishikawa T, Masuda T, Hachiya T, Dina C, Simonet F, Nagata Y, Tanck MWT, Sonehara K, Glinge C, Tadros R, Khongphatthanayothin A, Lu TP, Higuchi C, Nakajima T, Hayashi K, Aizawa Y, Nakano Y, Nogami A, Morita H, Ohno S, Aiba T, Krijger Ju?rez C, Mauleekoonphairoj J, Poovorawan Y, Gourraud JB, Shimizu W, Probst V, Horie M, Wilde AAM, Redon R, Juang JJ, Nademanee K, Bezzina CR, Barc J, Tanaka T, Okada Y, Schott JJ, Makita N. Brugada syndrome in Japan and Europe: a genome-wide association study reveals shared genetic architecture and new risk loci. Eur Heart J. 2024 Jul 09; 45(26):2320-2332. PMID: 38747976.
      Citations:    
    18. Ko YC, Tsai TY, Wu CK, Lin KW, Hsieh MJ, Lu TP, Matsuyama T, Chiang WC, Ma MH. Effectiveness and safety of tourniquet utilization for civilian vascular extremity trauma in the pre-hospital settings: a systematic review and meta-analysis. World J Emerg Surg. 2024 Mar 19; 19(1):10. PMID: 38504263; PMCID: PMC10949629.
      Citations:    
    19. Hsieh MS, Chiu KC, Chattopadhyay A, Lu TP, Liao SH, Chang CM, Lee YC, Lo WE, Hsieh VC, Hu SY, How CK. Utilizing the National Early Warning Score 2 (NEWS2) to confirm the impact of emergency department management in sepsis patients: a cohort study from taiwan 1998-2020. Int J Emerg Med. 2024 Mar 15; 17(1):42. PMID: 38491434; PMCID: PMC10941441.
      Citations:    
    20. Park YJ, Lu TC, Jackson T, Goodman LD, Ran L, Chen J, Liang CY, Harrison E, Ko C, Hsu AL, Yamamoto S, Qi Y, Bellen HJ, Li H. Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models. bioRxiv. 2024 Mar 13. PMID: 38559164; PMCID: PMC10979927.
      Citations:    
    21. Hsu YC, Chiu YC, Lu TP, Hsiao TH, Chen Y. Predicting drug response through tumor deconvolution by cancer cell lines. Patterns (N Y). 2024 Apr 12; 5(4):100949. PMID: 38645769; PMCID: PMC11026976.
      Citations:    
    22. Tsai YL, Kang YT, Chan HC, Chattopadhyay A, Chiang CJ, Lee WC, Cheng SH, Lu TP. Population-Based Prognostic Models for Head and Neck Cancers Using National Cancer Registry Data from Taiwan. J Epidemiol Glob Health. 2024 Jun; 14(2):433-443. PMID: 38353918; PMCID: PMC11176144.
      Citations:    
    23. Tsai YL, Yu PC, Nien HH, Lu TP. Time variation of high-risk groups for liver function deteriorations within fluctuating long-term liver function after hepatic radiotherapy in patients with hepatocellular carcinoma. Eur J Med Res. 2024 Feb 07; 29(1):104. PMID: 38326881; PMCID: PMC10848403.
      Citations:    
    24. Chattopadhyay A, Lee CY, Lee YC, Liu CL, Chen HK, Li YH, Lai LC, Tsai MH, Ni YH, Chiu HM, Lu TP, Chuang EY. Twnbiome: a public database of the healthy Taiwanese gut microbiome. BMC Bioinformatics. 2023 Dec 14; 24(1):474. PMID: 38097965; PMCID: PMC10722848.
      Citations:    
    25. Jeng XJ, Hu Y, Venkat V, Lu TP, Tzeng JY. Transfer learning with false negative control improves polygenic risk prediction. PLoS Genet. 2023 Nov; 19(11):e1010597. PMID: 38011285; PMCID: PMC10723713.
      Citations:    
    26. Wang B, Martini-Stoica H, Qi C, Lu TC, Wang S, Xiong W, Qi Y, Xu Y, Sardiello M, Li H, Zheng H. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy. Nat Neurosci. 2024 Jan; 27(1):48-62. PMID: 37985800; PMCID: PMC12203451.
      Citations:    Fields:    Translation:AnimalsCells
    27. Hsu YC, Chen HL, Cheng CF, Chattopadhyay A, Chen PS, Lin CC, Chiang HY, Liu TY, Huang CH, Kuo CC, Chuang EY, Lu TP, Tsai FJ. The largest genome-wide association study for breast cancer in Taiwanese Han population. Breast Cancer Res Treat. 2024 Jan; 203(2):291-306. PMID: 37851288.
      Citations:    
    28. Lee JC, Hsieh TH, Kao YC, Tsai CF, Huang HY, Shih CY, Song HL, Oda Y, Chih-Hsueh Chen P, Pan CC, Sittampalam K, Petersson F, Konishi E, Chiu WY, Chen CF, Carpenter TO, Lu TP, Chang CD, Huang SC, Folpe AL. Klotho Overexpression Is Frequently Associated With Upstream Rearrangements in Fusion-Negative Phosphaturic Mesenchymal Tumors of Bone and Sinonasal Tract. Mod Pathol. 2023 12; 36(12):100336. PMID: 37742927.
      Citations:    
    29. Kuo SH, Tseng LM, Chen ST, Sagara Y, Chang YC, Yeh HT, Kuo YL, Hung CC, Lu TP, Lee YH, Toi M, Huang CS. Radiotherapy versus low-dose tamoxifen following breast-conserving surgery for low-risk and estrogen receptor-positive breast ductal carcinoma in situ: an international open-label randomized non-inferiority trial (TBCC-ARO DCIS Trial). BMC Cancer. 2023 Sep 14; 23(1):865. PMID: 37710198; PMCID: PMC10500726.
      Citations:    
    30. Fan HY, Chien KL, Huang YT, Hsu JB, Chen YY, Lai EY, Su JY, Lu TP, Li HY, Hsu SY, Chen YC. Hypertension as a Novel Link for Shared Heritability in Age at Menarche and Cardiometabolic Traits. J Clin Endocrinol Metab. 2023 08 18; 108(9):2389-2399. PMID: 36810613.
      Citations:    
    31. Han HJ, Huang CS, Lu TP, Tseng LM, Chie WC, Huang CC. Evaluating clinical efficacy of hospital-based surveillance with mammography and ultrasonography for breast cancer. J Formos Med Assoc. 2024 Jan; 123(1):78-87. PMID: 37400295.
      Citations:    
    32. Lu TC, Brbic M, Park YJ, Jackson T, Chen J, Kolluru SS, Qi Y, Katheder NS, Cai XT, Lee S, Chen YC, Auld N, Liang CY, Ding SH, Welsch D, D'Souza S, Pisco AO, Jones RC, Leskovec J, Lai EC, Bellen HJ, Luo L, Jasper H, Quake SR, Li H. Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution. Science. 2023 06 16; 380(6650):eadg0934. PMID: 37319212; PMCID: PMC10829769.
      Citations: 10     Fields:    Translation:AnimalsCells
    33. Chattopadhyay A, Lee CY, Shen YC, Lu KC, Hsiao TH, Lin CH, Lai LC, Tsai MH, Lu TP, Chuang EY. Multi-ethnic Imputation System (MI-System): A genotype imputation server for high-dimensional data. J Biomed Inform. 2023 07; 143:104423. PMID: 37308034.
      Citations:    
    34. Hsieh MS, Chattopadhyay A, Lu TP, Liao SH, Chang CM, Lee YC, Lo WE, Wu JJ, Hsieh VC, Hu SY, How CK. Effect of end-stage kidney disease on the return of spontaneous circulation in Taiwanese adults with out-of-hospital cardiac arrest. Sci Rep. 2023 05 16; 13(1):7905. PMID: 37193783; PMCID: PMC10188509.
      Citations:    
    35. Chuang JH, Chen PH, Lu TP, Hung WT, Liao HC, Tsai TM, Lin MW, Chen KC, Hsu HH, Chen JS. Uniportal versus multiportal nonintubated thoracoscopic anatomical resection for lung cancer: A propensity-matched analysis. J Formos Med Assoc. 2023 Sep; 122(9):947-954. PMID: 37169655.
      Citations:    
    36. Lee KY, Liu CM, Chen LH, Lee CY, Lu TP, Chuang LL, Lai LC. Hypoxia-responsive circular RNA circAAGAB reduces breast cancer malignancy by activating p38 MAPK and sponging miR-378?h. Cancer Cell Int. 2023 Mar 10; 23(1):45. PMID: 36899354; PMCID: PMC10007766.
      Citations:    
    37. Hsieh YC, Lo C, Lee YH, Chien N, Lu TP, Tsai LW, Wang MY, Kuo WH, Chang YC, Huang CS. High rate of postoperative upstaging of ductal carcinoma in situ when prioritizing ultrasound evaluation of mammography-detected lesions: a single-center retrospective cohort study. World J Surg Oncol. 2023 Feb 17; 21(1):48. PMID: 36804000; PMCID: PMC9936646.
      Citations:    
    38. Wang B, Martini-Stoica H, Qi C, Lu TC, Wang S, Xiong W, Qi Y, Xu Y, Sardiello M, Li H, Zheng H. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy. bioRxiv. 2023 Feb 06. PMID: 36798205; PMCID: PMC9934527.
      Citations:    
    39. Wu CH, Liu KL, Liang PC, Lu TP, Kuo TC, Tien YW. Transcatheter fistula tract occlusion: a safe and effective treatment for grade B postoperative pancreatic fistula. HPB (Oxford). 2023 04; 25(4):481-483. PMID: 37028828.
      Citations:    
    40. Fan HY, Lin WY, Lu TP, Chen YY, Hsu JB, Yu SL, Su TC, Lin HJ, Chen YC, Chien KL. Targeted next-generation sequencing for genetic variants of left ventricular mass status among community-based adults in Taiwan. Front Genet. 2022; 13:1064980. PMID: 36712865; PMCID: PMC9879005.
      Citations:    
    41. Hsieh MS, Chattopadhyay A, Lu TP, Liao SH, Chang CM, Lee YC, Lo WE, Wu JJ, Hsieh VC, Hu SY, How CK. End-Stage Renal Disease Patients Undergoing Hemodialysis Have Higher Possibility of Return of Spontaneous Circulation during Out-of-Hospital Cardiac Arrest and Non-Inferior Short-Term Survival. J Clin Med. 2022 Nov 06; 11(21). PMID: 36362810; PMCID: PMC9659049.
      Citations:    
    42. Chattopadhyay A, Shih CY, Hsu YC, Juang JJ, Chuang EY, Lu TP. CLIN_SKAT: an R package to conduct association analysis using functionally relevant variants. BMC Bioinformatics. 2022 Oct 23; 23(1):441. PMID: 36274122; PMCID: PMC9590128.
      Citations:    
    43. Huang PH, Yang TY, Yeh CW, Huang SM, Chang HC, Hung YF, Chu WC, Cho KH, Lu TP, Kuo PH, Lee LJ, Kuo LW, Lien CC, Cheng HJ. Involvement of a BH3-only apoptosis sensitizer gene Blm-s in hippocampus-mediated mood control. Transl Psychiatry. 2022 09 26; 12(1):411. PMID: 36163151; PMCID: PMC9512807.
      Citations:    
    44. Chao HH, Luo JL, Hsu MH, Chen LH, Lu TP, Tsai MH, Chuang EY, Chuang LL, Lai LC. Regulatory mechanisms and function of hypoxia-induced long noncoding RNA NDRG1-OT1 in breast cancer cells. Cell Death Dis. 2022 09 20; 13(9):807. PMID: 36127332; PMCID: PMC9489765.
      Citations:    
    45. Lin YJ, Burkhart R, Lu TP, Wolfgang C, Wright M, Zheng L, Wu HY, Chen CH, Lee SY, Wu CH, He J, Tien YW. Solid Pseudopapillary Neoplasms of the Pancreas Across Races Demonstrate Disparities with Comparably Good Prognosis. World J Surg. 2022 12; 46(12):3072-3080. PMID: 36066663.
      Citations:    
    46. Kuo SW, Chen PH, Lu TP, Chen KC, Liao HC, Tsou KC, Tsai TM, Lin MW, Hsu HH, Chen JS. Correction to: Primary Tumor Resection for Stage IV Non-small-cell Lung Cancer Without Progression After First-Line Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Treatment: A Retrospective Case-Control Study. Ann Surg Oncol. 2022 Aug; 29(8):4922. PMID: 35397741.
      Citations:    
    47. Huang CH, Chang MC, Lai YC, Lin CY, Hsu CH, Tseng BY, Hsiao CK, Lu TP, Yu SL, Hsieh ST, Chen WJ. Mitochondrial DNA methylation profiling of the human prefrontal cortex and nucleus accumbens: correlations with aging and drug use. Clin Epigenetics. 2022 06 25; 14(1):79. PMID: 35752846; PMCID: PMC9233363.
      Citations:    
    48. Chen PH, Chuang JH, Lu TP, Hung WT, Liao HC, Tsai TM, Lin MW, Chen KC, Hsu HH, Chen JS. Non-Intubated Versus Intubated Video-Assisted Thoracic Surgery in Patients Aged 75 Years and Older: A Propensity Matching Study. Front Surg. 2022; 9:880007. PMID: 35586501; PMCID: PMC9108723.
      Citations:    
    49. Shivani S, Kao CY, Chattopadhyay A, Chen JW, Lai LC, Lin WH, Lu TP, Huang IH, Tsai MH, Teng CH, Wu JJ, Hsieh YH, Wang MC, Chuang EY. Uremic Toxin-Producing Bacteroides Species Prevail in the Gut Microbiota of Taiwanese CKD Patients: An Analysis Using the New Taiwan Microbiome Baseline. Front Cell Infect Microbiol. 2022; 12:726256. PMID: 35558102; PMCID: PMC9086402.
      Citations:    
    50. Lu TP, Kamatani Y, Belbin G, Park T, Hsiao CK. Editorial: Current Status and Future Challenges of Biobank Data Analysis. Front Genet. 2022; 13:882611. PMID: 35495141; PMCID: PMC9047950.
      Citations:    
    51. Kuo SW, Chen PH, Lu TP, Chen KC, Liao HC, Tsou KC, Tsai TM, Lin MW, Hsu HH, Chen JS. Primary Tumor Resection for Stage IV Non-small-cell Lung Cancer Without Progression After First-Line Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Treatment: A Retrospective Case-Control Study. Ann Surg Oncol. 2022 Aug; 29(8):4873-4884. PMID: 35254583.
      Citations:    
    52. Kao YC, Kuo CT, Kuo PY, Huang HY, Lu TP, Hsieh TH, Fletcher CDM, Lee JC. Pulmonary "Inflammatory Leiomyosarcomas" Are Indolent Tumors With Diploid Genomes and No Convincing Rhabdomyoblastic Differentiation. Am J Surg Pathol. 2022 03 01; 46(3):424-433. PMID: 35175969.
      Citations:    
    53. Huang CS, Tsai ML, Lu TP, Tu CC, Liu CY, Huang CJ, Ho YS, Tu SH, Chuang EY, Tseng LM, Huang CC. The extended concurrent genes signature for disease-free survival in breast cancer. J Formos Med Assoc. 2022 Oct; 121(10):1945-1955. PMID: 35181201.
      Citations:    
    54. Lin YJ, Chiang XH, Lu TP, Hsieh MS, Lin MW, Hsu HH, Chen JS. Thoracoscopic Lobectomy Versus Sublobar Resection for pStage I Geriatric Non-Small Cell Lung Cancer. Front Oncol. 2021; 11:777590. PMID: 35141143; PMCID: PMC8818756.
      Citations:    
    55. Chen MZ, Su LY, Ko PH, Hsu MH, Chuang LL, Chen LH, Lu TP, Chuang EY, Chow LP, Tsai MH, Hsu HH, Lai LC. Extracellular domain of semaphorin 5A serves a tumor-suppressing role by activating interferon signaling pathways in lung adenocarcinoma cells. Int J Oncol. 2022 Feb; 60(2). PMID: 35059729.
      Citations:    
    56. Lin CY, Tseng WT, Chang YY, Tsai MH, Chuang EY, Lu TP, Lai LC. Lidocaine and Bupivacaine Downregulate MYB and DANCR lncRNA by Upregulating miR-187-5p in MCF-7 Cells. Front Med (Lausanne). 2021; 8:732817. PMID: 35096852; PMCID: PMC8792760.
      Citations:    
    57. Chiu PC, Chattopadhyay A, Wu MC, Hsiao TH, Lin CH, Lu TP. Elucidation of a Causal Relationship Between Platelet Count and Hypertension: A Bi-Directional Mendelian Randomization Study. Front Cardiovasc Med. 2021; 8:743075. PMID: 34901208; PMCID: PMC8661012.
      Citations:    
    58. Chen WJ, Chen CY, Wu SC, Wu KC, Jou S, Tung YC, Lu TP. The impact of Taiwan's implementation of a nationwide harm reduction program in 2006 on the use of various illicit drugs: trend analysis of first-time offenders from 2001 to 2017. Harm Reduct J. 2021 11 19; 18(1):117. PMID: 34798883; PMCID: PMC8603590.
      Citations:    
    59. Fang W, Wu CH, Sun QL, Gu ZT, Zhu L, Mao T, Zhang XF, Xu N, Lu TP, Tsai MH, Chen LH, Lai LC, Chuang EY. Novel Tumor-Specific Antigens for Immunotherapy Identified From Multi-omics Profiling in Thymic Carcinomas. Front Immunol. 2021; 12:748820. PMID: 34867976; PMCID: PMC8635231.
      Citations:    
    60. Lu TP, Wu CH, Chang CC, Chan HC, Chattopadhyay A, Lee WC, Chiang CJ, Lee HY, Tien YW. Distinct Survival Outcomes in Subgroups of Stage III Pancreatic Cancer Patients: Taiwan Cancer Registry and Surveillance, Epidemiology and End Results registry. Ann Surg Oncol. 2022 Mar; 29(3):1608-1615. PMID: 34775547; PMCID: PMC8810458.
      Citations:    
    61. Phan NN, Chattopadhyay A, Lee TT, Yin HI, Lu TP, Lai LC, Hwa HL, Tsai MH, Chuang EY. High-performance deep learning pipeline predicts individuals in mixtures of DNA using sequencing data. Brief Bioinform. 2021 11 05; 22(6). PMID: 34368845.
      Citations:    
    62. Chi JT, Ipsen ICF, Hsiao TH, Lin CH, Wang LS, Lee WP, Lu TP, Tzeng JY. SEAGLE: A Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests in Biobank Data. Front Genet. 2021; 12:710055. PMID: 34795690; PMCID: PMC8593472.
      Citations:    
    63. Lu TP, Chattopadhyay A, Lu KC, Chuang JY, Yeh SS, Chang IS, Chen CJ, Wu IC, Hsu CC, Chen TY, Tseng WT, Hsiung CA, Juang JJ. Develop and Apply Electrocardiography-Based Risk Score to Identify Community-Based Elderly Individuals at High-Risk of Mortality. Front Cardiovasc Med. 2021; 8:738061. PMID: 34692790; PMCID: PMC8531436.
      Citations:    
    64. Chiang YC, Lin PH, Lu TP, Kuo KT, Tai YJ, Hsu HC, Wu CY, Lee CY, Shen H, Chen CA, Cheng WF. A DNA Damage Response Gene Panel for Different Histologic Types of Epithelial Ovarian Carcinomas and Their Outcomes. Biomedicines. 2021 Oct 03; 9(10). PMID: 34680501; PMCID: PMC8533221.
      Citations:    
    65. Wu CH, Hsieh CS, Chang YC, Huang CC, Yeh HT, Hou MF, Chung YC, Tu SH, Chang KJ, Chattopadhyay A, Lai LC, Lu TP, Li YH, Tsai MH, Chuang EY. Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population. Commun Biol. 2021 09 09; 4(1):1052. PMID: 34504292; PMCID: PMC8429690.
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    66. Yu QY, Lu TP, Hsiao TH, Lin CH, Wu CY, Tzeng JY, Hsiao CK. An Integrative Co-localization (INCO) Analysis for SNV and CNV Genomic Features With an Application to Taiwan Biobank Data. Front Genet. 2021; 12:709555. PMID: 34567069; PMCID: PMC8456116.
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    67. Minahan NT, Chen CH, Shen WC, Lu TP, Kallawicha K, Tsai KH, Guo YL. Fungal Spore Richness in School Classrooms is Related to Surrounding Forest in a Season-Dependent Manner. Microb Ecol. 2022 Aug; 84(2):351-362. PMID: 34498118.
      Citations:    
    68. Chen YJ, Huang CS, Phan NN, Lu TP, Liu CY, Huang CJ, Chiu JH, Tseng LM, Huang CC. Molecular subtyping of breast cancer intrinsic taxonomy with oligonucleotide microarray and NanoString nCounter. Biosci Rep. 2021 08 27; 41(8). PMID: 34387660; PMCID: PMC8385191.
      Citations:    
    69. Chang SM, Yang M, Lu W, Huang YJ, Huang Y, Hung H, Miecznikowski JC, Lu TP, Tzeng JY. Gene-set integrative analysis of multi-omics data using tensor-based association test. Bioinformatics. 2021 Aug 25; 37(16):2259-2265. PMID: 33674827; PMCID: PMC8388036.
      Citations:    
    70. Chan HC, Huang CC, Huang CC, Chattopadhyay A, Yeh KH, Lee WC, Chiang CJ, Lee HY, Cheng SH, Lu TP. Predicting Colon Cancer-Specific Survival for the Asian Population Using National Cancer Registry Data from Taiwan. Ann Surg Oncol. 2022 Feb; 29(2):853-863. PMID: 34427821.
      Citations:    
    71. Lee CY, Lee YF, Lai LC, Tsai MH, Lu TP, Chuang EY. MiDSystem: A comprehensive online system for de novo assembly and analysis of microbial genomes. N Biotechnol. 2021 Nov 25; 65:42-52. PMID: 34411700.
      Citations:    
    72. Lei L, Chan HC, Lu TP, Cheng SH. Risk evaluation of early-stage hormone receptor-positive and human epidermal growth factor receptor 2-negative breast cancer patients: a population-based study from Taiwan. Breast Cancer Res Treat. 2021 Oct; 189(3):807-815. PMID: 34282518.
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    73. Chattopadhyay A, Teoh ZH, Wu CY, Juang JJ, Lai LC, Tsai MH, Wu CH, Lu TP, Chuang EY. CNVIntegrate: the first multi-ethnic database for identifying copy number variations associated with cancer. Database (Oxford). 2021 07 14; 2021. PMID: 34259866; PMCID: PMC8278790.
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    74. Lin CH, Huang RY, Lu TP, Kuo KT, Lo KY, Chen CH, Chen IC, Lu YS, Chuang EY, Thiery JP, Huang CS, Cheng AL. High prevalence of APOA1/C3/A4/A5 alterations in luminal breast cancers among young women in East Asia. NPJ Breast Cancer. 2021 Jul 05; 7(1):88. PMID: 34226567; PMCID: PMC8257799.
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    75. Huang CS, Liu CY, Lu TP, Huang CJ, Chiu JH, Tseng LM, Huang CC. Targeted Sequencing of Taiwanese Breast Cancer with Risk Stratification by the Concurrent Genes Signature: A Feasibility Study. J Pers Med. 2021 Jun 28; 11(7). PMID: 34203389; PMCID: PMC8306786.
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    76. Chiang XH, Lu TP, Hsieh MS, Tsai TM, Liao HC, Kao TN, Chang CH, Lin MW, Hsu HH, Chen JS. Thoracoscopic Wedge Resection Versus Segmentectomy for cT1N0 Lung Adenocarcinoma. Ann Surg Oncol. 2021 Dec; 28(13):8398-8411. PMID: 34145505.
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    77. Cheng YC, Su LY, Chen LH, Lu TP, Chuang EY, Tsai MH, Chuang LL, Lai LC. Regulatory Mechanisms and Functional Roles of Hypoxia-Induced Long Non-Coding RNA MTORT1 in Breast Cancer Cells. Front Oncol. 2021; 11:663114. PMID: 34141617; PMCID: PMC8204045.
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    78. Shih CH, Chuang LL, Tsai MH, Chen LH, Chuang EY, Lu TP, Lai LC. Hypoxia-Induced MALAT1 Promotes the Proliferation and Migration of Breast Cancer Cells by Sponging MiR-3064-5p. Front Oncol. 2021; 11:658151. PMID: 34012919; PMCID: PMC8126986.
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    79. Wu CH, Yeh HT, Hsieh CS, Huang CC, Chattopadhyay A, Chung YC, Tu SH, Li YH, Lu TP, Lai LC, Hou MF, Chang KJ, Tsai MH, Chuang EY. Evolutionary Trajectories and Genomic Divergence in Localized Breast Cancers after Ipsilateral Breast Tumor Recurrence. Cancers (Basel). 2021 Apr 11; 13(8). PMID: 33920370; PMCID: PMC8069481.
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    80. Liu HY, Lu TP, Tao CW, Wu YJ, Huang WC, Hsu CH, Liao WC, Hsu HH, Lin MC, Yu CJ. Incidence of chronic thromboembolic pulmonary hypertension in Taiwan. J Formos Med Assoc. 2021 Sep; 120(9):1740-1748. PMID: 33846021.
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    81. Hung YM, Lu TP, Tsai MH, Lai LC, Chuang EY. EasyMAP: A user-friendly online platform for analyzing 16S ribosomal DNA sequencing data. N Biotechnol. 2021 Jul 25; 63:37-44. PMID: 33711505.
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    82. Cheng WC, Chang CY, Lo CC, Hsieh CY, Kuo TT, Tseng GC, Wong SC, Chiang SF, Huang KC, Lai LC, Lu TP, Chao KSC, Sher YP. Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma. Theranostics. 2021; 11(8):3661-3675. PMID: 33664854; PMCID: PMC7914355.
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    83. Huang CS, Lu TP, Liu CY, Huang CJ, Chiu JH, Chen YJ, Tseng LM, Huang CC. Residual risk stratification of Taiwanese breast cancers following curative therapies with the extended concurrent genes signature. Breast Cancer Res Treat. 2021 Apr; 186(2):475-485. PMID: 33392837.
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    84. Pan WH, Wu KC, Chen CY, Chu YR, Wu SC, Jou S, Lu TP, Tung YC, Hsu J, Chen WJ. First-time offenders for recreational ketamine use under a new penalty system in Taiwan: incidence, recidivism and mortality in national cohorts from 2009 to 2017. Addiction. 2021 07; 116(7):1770-1781. PMID: 33197101.
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    85. Juang JJ, Lu TP, Su MW, Lin CW, Yang JH, Chu HW, Chen CH, Hsiao YW, Lee CY, Chiang LM, Yu QY, Hsiao CK, Chen CJ, Wu PE, Pai CH, Chuang EY, Shen CY. Rare variants discovery by extensive whole-genome sequencing of the Han Chinese population in Taiwan: Applications to cardiovascular medicine. J Adv Res. 2021 05; 30:147-158. PMID: 34026292; PMCID: PMC8132201.
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    86. Phan NN, Chattopadhyay A, Lu TP, Tsai MH. Leveraging well-annotated databases for deep learning in biomedical research. Transl Cancer Res. 2020 Dec; 9(12):7682-7684. PMID: 35117369; PMCID: PMC8798879.
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    87. Chen CJ, Su MM, Liao YC, Chang FL, Wu CK, Lin LY, Chen YS, Lin YH, Hwang JJ, Yu SL, Kao HL, Chen WJ, Lu TP, Shih CY, Yeh SS, Yang DH, Lai LP, Juang JJ. Long-term outcomes and left ventricular diastolic function of sarcomere mutation-positive and mutation-negative patients with hypertrophic cardiomyopathy: a prospective cohort study. Eur Heart J Cardiovasc Imaging. 2020 Nov 22. PMID: 33221870.
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    88. Liang CW, Yang CY, Flavin R, Fletcher JA, Lu TP, Lai IR, Li YI, Chang YL, Lee JC. Loss of SFRP1 expression is a key progression event in gastrointestinal stromal tumor pathogenesis. Hum Pathol. 2021 01; 107:69-79. PMID: 33186588.
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    89. Lin HJ, Yu SL, Su TC, Hsu HC, Chen MF, Lee YT, Chien KL, Lu TP. Statin-induced microRNAome alterations modulating inflammation pathways of peripheral blood mononuclear cells in patients with hypercholesterolemia. Biosci Rep. 2020 09 30; 40(9). PMID: 32885808; PMCID: PMC7507599.
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    90. Peng YC, Wu CH, Tien YW, Lu TP, Wang YH, Chen BB. Preoperative sarcopenia is associated with poor overall survival in pancreatic cancer patients following pancreaticoduodenectomy. Eur Radiol. 2021 Apr; 31(4):2472-2481. PMID: 32974690.
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    91. Liu HY, Hsu HH, Tsai TM, Chiang XH, Lu TP, Chang CH, Chen PH, Wang ML, Hung MH, Cheng YJ, Lin MW, Chen JS. Nonintubated Versus Intubated Uniportal Thoracoscopic Segmentectomy for Lung Tumors. Ann Thorac Surg. 2021 04; 111(4):1182-1189. PMID: 32857994.
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    92. Juang JJ, Binda A, Lee SJ, Hwang JJ, Chen WJ, Liu YB, Lin LY, Yu CC, Ho LT, Huang HC, Chen CJ, Lu TP, Lai LC, Yeh SS, Lai LP, Chuang EY, Rivolta I, Antzelevitch C. GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death. EBioMedicine. 2020 Jul; 57:102843. PMID: 32645615; PMCID: PMC7341360.
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    93. Chen WJ, Yang SY, Chang JC, Cheng WC, Lu TP, Wang YN, Juan MH, Hsu RT, Huang SR, Tu JJ, Wang PC, Feng VW, Chang PZ. Development of a semi-structured, multifaceted, computer-aided questionnaire for outbreak investigation: e-Outbreak Platform. Biomed J. 2020 08; 43(4):318-324. PMID: 32654885; PMCID: PMC7305507.
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    94. Jimmy Juang JM, Liu YB, Julius Chen CY, Yu QY, Chattopadhyay A, Lin LY, Chen WJ, Yu CC, Huang HC, Ho LT, Lai LP, Hwang JJ, Lin TT, Liao MT, Chen JJ, Sherri Yeh SF, Chuang JY, Yang DH, Lin JL, Lu TP, Chuang EY, Ackerman MJ. Validation and Disease Risk Assessment of Previously Reported Genome-Wide Genetic Variants Associated With Brugada Syndrome: SADS-TW BrS Registry. Circ Genom Precis Med. 2020 08; 13(4):e002797. PMID: 32490690; PMCID: PMC7439932.
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    95. Brucker A, Lu W, Marceau West R, Yu QY, Hsiao CK, Hsiao TH, Lin CH, Magnusson PKE, Sullivan PF, Szatkiewicz JP, Lu TP, Tzeng JY. Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis. PLoS Comput Biol. 2020 05; 16(5):e1007797. PMID: 32365089; PMCID: PMC7224564.
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    96. Huang TT, Lei L, Chen CA, Lu TP, Jen CW, Cheng SH. A new clinical-genomic model to predict 10-year recurrence risk in primary operable breast cancer patients. Sci Rep. 2020 03 17; 10(1):4861. PMID: 32184406; PMCID: PMC7078190.
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    97. Chen CC, Wu WK, Chang CM, Panyod S, Lu TP, Liou JM, Fang YJ, Chuang EY, Wu MS. Comparison of DNA stabilizers and storage conditions on preserving fecal microbiota profiles. J Formos Med Assoc. 2020 Dec; 119(12):1791-1798. PMID: 32111519.
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    98. Liou JM, Chen CC, Chang CM, Fang YJ, Bair MJ, Chen PY, Chang CY, Hsu YC, Chen MJ, Chen CC, Lee JY, Yang TH, Luo JC, Chen CY, Hsu WF, Chen YN, Wu JY, Lin JT, Lu TP, Chuang EY, El-Omar EM, Wu MS, Taiwan Gastrointestinal Disease and Helicobacter Consortium. Long-term changes of gut microbiota, antibiotic resistance, and metabolic parameters after Helicobacter pylori eradication: a multicentre, open-label, randomised trial. Lancet Infect Dis. 2019 10; 19(10):1109-1120. PMID: 31559966.
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    99. Lai LC, Sun QL, Chen YA, Hsiao YW, Lu TP, Tsai MH, Zhu L, Chuang EY, Fang W. Using proteomic profiling to characterize protein signatures of different thymoma subtypes. BMC Cancer. 2019 Aug 13; 19(1):796. PMID: 31409307; PMCID: PMC6693091.
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    100. Huang CC, Chan SY, Lee WC, Chiang CJ, Lu TP, Cheng SH. Development of a prediction model for breast cancer based on the national cancer registry in Taiwan. Breast Cancer Res. 2019 08 13; 21(1):92. PMID: 31409418; PMCID: PMC6691540.
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    101. Chen CH, Lu YS, Cheng AL, Huang CS, Kuo WH, Wang MY, Chao M, Chen IC, Kuo CW, Lu TP, Lin CH. Disparity in Tumor Immune Microenvironment of Breast Cancer and Prognostic Impact: Asian Versus Western Populations. Oncologist. 2020 01; 25(1):e16-e23. PMID: 31371522; PMCID: PMC6964121.
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    102. Huang TT, Chen AC, Lu TP, Lei L, Cheng SH. Clinical-Genomic Models of Node-Positive Breast Cancer: Training, Testing, and Validation. Int J Radiat Oncol Biol Phys. 2019 11 01; 105(3):637-648. PMID: 31295565.
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    103. Lee CH, Kao YC, Lee WR, Hsiao YW, Lu TP, Chu CY, Lin YJ, Huang HY, Hsieh TH, Liu YR, Liang CW, Chen TW, Yip S, Lum A, Kuo KT, Jeng YM, Yu SC, Chung YC, Lee JC. Clinicopathologic Characterization of GREB1-rearranged Uterine Sarcomas With Variable Sex-Cord Differentiation. Am J Surg Pathol. 2019 07; 43(7):928-942. PMID: 31094921.
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    104. Lee YC, Chao YL, Chang CE, Hsieh MH, Liu KT, Chen HC, Lu ML, Chen WY, Chen CH, Tsai MH, Lu TP, Huang MC, Kuo PH. Transcriptome Changes in Relation to Manic Episode. Front Psychiatry. 2019; 10:280. PMID: 31118907; PMCID: PMC6504680.
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    105. Lu TP, Kuo KT, Chen CH, Chang MC, Lin HP, Hu YH, Chiang YC, Cheng WF, Chen CA. Developing a Prognostic Gene Panel of Epithelial Ovarian Cancer Patients by a Machine Learning Model. Cancers (Basel). 2019 Feb 25; 11(2). PMID: 30823599; PMCID: PMC6406249.
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    106. Chen CJ, Lu TP, Lin LY, Liu YB, Ho LT, Huang HC, Lai LP, Hwang JJ, Yeh SS, Wu CK, Juang JJ, Antzelevitch C. Impact of Ancestral Differences and Reassessment of the Classification of Previously Reported Pathogenic Variants in Patients With Brugada Syndrome in the Genomic Era: A SADS-TW BrS Registry. Front Genet. 2018; 9:680. PMID: 30662450; PMCID: PMC6328444.
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    107. Lee CY, Chattopadhyay A, Chiang LM, Juang JJ, Lai LC, Tsai MH, Lu TP, Chuang EY. VariED: the first integrated database of gene annotation and expression profiles for variants related to human diseases. Database (Oxford). 2019 01 01; 2019. PMID: 31317185; PMCID: PMC6637258.
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    108. Chang SY, Chen ML, Lee MR, Liang YC, Lu TP, Wang JY, Yan BS. SP110 Polymorphisms Are Genetic Markers for Vulnerability to Latent and Active Tuberculosis Infection in Taiwan. Dis Markers. 2018; 2018:4687380. PMID: 30627224; PMCID: PMC6304864.
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    109. Shen CY, Chang YC, Chen LH, Lin WC, Lee YH, Yeh ST, Chen HK, Fang W, Hsu CP, Lee JM, Lu TP, Hsiao PW, Lai LC, Tsai MH, Chuang EY. The extracellular SEMA domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells. Oncogenesis. 2018 Dec 05; 7(12):95. PMID: 30518871; PMCID: PMC6281666.
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    110. Lin EP, Lin CH, Yang CY, Lu TP, Chang SN, Hsiao TH, Huang BT, Yu CJ, Chan KA, Yang PC. Population-Based Cohort Study Reveals Distinct Associations Between Female Lung Cancer and Breast Cancer in Taiwan. JCO Clin Cancer Inform. 2018 12; 2:1-14. PMID: 30652619.
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    111. Lin EP, Hsiao TH, Lu JY, Wong SH, Lu TP, Peck K, Takahashi T, Yang PC. Translating Gene Signatures Into a Pathologic Feature: Tumor Necrosis Predicts Disease Relapse in Operable and Stage I Lung Adenocarcinoma. JCO Precis Oncol. 2018 Nov; 2:1-13. PMID: 35135134.
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    112. Lin HW, Fu CF, Chang MC, Lu TP, Lin HP, Chiang YC, Chen CA, Cheng WF. CDH1, DLEC1 and SFRP5 methylation panel as a prognostic marker for advanced epithelial ovarian cancer. Epigenomics. 2018 11; 10(11):1397-1413. PMID: 30324802.
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    113. Lee CY, Hsieh PH, Chiang LM, Chattopadhyay A, Li KY, Lee YF, Lu TP, Lai LC, Lin EC, Lee H, Ding ST, Tsai MH, Chen CY, Chuang EY. Whole-genome de novo sequencing reveals unique genes that contributed to the adaptive evolution of the Mikado pheasant. Gigascience. 2018 05 01; 7(5). PMID: 29722814; PMCID: PMC5941149.
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    114. Lin CY, Cho CF, Bai ST, Liu JP, Kuo TT, Wang LJ, Lin YS, Lin CC, Lai LC, Lu TP, Hsieh CY, Chu CN, Cheng DC, Sher YP. ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT. Sci Rep. 2017 11 08; 7(1):15108. PMID: 29118335; PMCID: PMC5678093.
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    115. Hsiue EH, Hsu C, Tseng LH, Lu TP, Kuo KT. Epithelioid Trophoblastic Tumor Around an Abdominal Cesarean Scar: A Pathologic and Molecular Genetic Analysis. Int J Gynecol Pathol. 2017 Nov; 36(6):562-567. PMID: 28134666.
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    116. Yao CY, Chen CH, Huang HH, Hou HA, Lin CC, Tseng MH, Kao CJ, Lu TP, Chou WC, Tien HF. A 4-lncRNA scoring system for prognostication of adult myelodysplastic syndromes. Blood Adv. 2017 Aug 22; 1(19):1505-1516. PMID: 29296792; PMCID: PMC5728469.
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    117. Su SY, Lee WC, Chen TT, Wang HC, Su TC, Jeng JS, Tu YK, Liao SF, Lu TP, Chien KL. An evaluation of the 25 by 25 goal for premature cardiovascular disease mortality in Taiwan: an age-period-cohort analysis, population attributable fraction and national population-based study. Heart Asia. 2017; 9(2):e010905. PMID: 29467836; PMCID: PMC5818053.
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    118. Woolston AL, Hsiao PC, Kuo PH, Wang SH, Lien YJ, Liu CM, Hwu HG, Lu TP, Chuang EY, Chang LC, Chen CH, Wu JY, Tsuang MT, Chen WJ. Genetic loci associated with an earlier age at onset in multiplex schizophrenia. Sci Rep. 2017 07 25; 7(1):6486. PMID: 28744025; PMCID: PMC5527118.
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    119. Chiu YC, Wang LJ, Lu TP, Hsiao TH, Chuang EY, Chen Y. Differential correlation analysis of glioblastoma reveals immune ceRNA interactions predictive of patient survival. BMC Bioinformatics. 2017 Feb 28; 18(1):132. PMID: 28241741; PMCID: PMC5330036.
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    120. Lenka G, Tsai MH, Lin HC, Hsiao JH, Lee YC, Lu TP, Lee JM, Hsu CP, Lai LC, Chuang EY. Identification of Methylation-Driven, Differentially Expressed STXBP6 as a Novel Biomarker in Lung Adenocarcinoma. Sci Rep. 2017 02 15; 7:42573. PMID: 28198450; PMCID: PMC5309775.
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    121. Lu TP, Chuang NC, Cheng CY, Hsu CA, Wang YC, Lin YH, Lee JK, Wu CK, Hwang JJ, Lin LY, Yeh SS, Chien KL, Juang JJ. Genome-wide methylation profiles in coronary artery ectasia. Clin Sci (Lond). 2017 Apr 01; 131(7):583-594. PMID: 28143891.
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    122. Wu HL, Hsiao TH, Chen PJ, Wong SH, Kao JH, Chen DS, Lu JY, Lu TP, Chen Y, Chuang EY, Tu HC, Liu CJ. Liver Gene Expression Profiles Correlate with Virus Infection and Response to Interferon Therapy in Chronic Hepatitis B Patients. Sci Rep. 2016 08 22; 6:31349. PMID: 27546197; PMCID: PMC4992874.
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    123. Lee JC, Lu TP, Changou CA, Liang CW, Huang HN, Lauria A, Huang HY, Lin CY, Chiang YC, Davidson B, Lin MC, Kuo KT. Genomewide copy number analysis of M?llerian adenosarcoma identified chromosomal instability in the aggressive subgroup. Mod Pathol. 2016 09; 29(9):1070-82. PMID: 27255164.
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    124. Chang CW, Lu TP, She CX, Feng YC, Hsiao CK. Gene-set Analysis with CGI Information for Differential DNA Methylation Profiling. Sci Rep. 2016 Apr 19; 6:24666. PMID: 27090937; PMCID: PMC4836301.
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    125. Hsiao TH, Chiu YC, Hsu PY, Lu TP, Lai LC, Tsai MH, Huang TH, Chuang EY, Chen Y. Differential network analysis reveals the genome-wide landscape of estrogen receptor modulation in hormonal cancers. Sci Rep. 2016 Mar 14; 6:23035. PMID: 26972162; PMCID: PMC4789788.
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    126. Chen IC, Chang YC, Lu YS, Chung KP, Huang CS, Lu TP, Kuo WH, Wang MY, Kuo KT, Wu PF, Hsueh TH, Shen CY, Lin CH, Cheng AL. Clinical Relevance of Liver Kinase B1(LKB1) Protein and Gene Expression in Breast Cancer. Sci Rep. 2016 Feb 15; 6:21374. PMID: 26877155; PMCID: PMC4753425.
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    127. George NI, Lu TP, Chang CW. Cost-sensitive Performance Metric for Comparing Multiple Ordinal Classifiers. Artif Intell Res. 2016; 5(1):135-143. PMID: 28070226; PMCID: PMC5217743.
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    128. Lu TP, Chen JJ. Subgroup identification for treatment selection in biomarker adaptive design. BMC Med Res Methodol. 2015 Dec 09; 15:105. PMID: 26646831; PMCID: PMC4673750.
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    129. Chen JJ, Lu TP, Chen YC, Lin WJ. Predictive biomarkers for treatment selection: statistical considerations. Biomark Med. 2015; 9(11):1121-35. PMID: 26507127.
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    130. Lu TP, Chen JJ. Identification of drug-induced toxicity biomarkers for treatment determination. Pharm Stat. 2015 Jul-Aug; 14(4):284-93. PMID: 25914330.
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    131. Lu TP, Hsiao CK, Lai LC, Tsai MH, Hsu CP, Lee JM, Chuang EY. Identification of regulatory SNPs associated with genetic modifications in lung adenocarcinoma. BMC Res Notes. 2015 Mar 24; 8:92. PMID: 25889623; PMCID: PMC4384239.
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    132. Chiang YC, Cheng WF, Chang MC, Lu TP, Kuo KT, Lin HP, Hsieh CY, Chen CA. Establishment of a New Ovarian Cancer Cell Line CA5171. Reprod Sci. 2015 Jun; 22(6):725-34. PMID: 25394645; PMCID: PMC4502800.
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    133. Chen HC, Zou W, Lu TP, Chen JJ. A composite model for subgroup identification and prediction via bicluster analysis. PLoS One. 2014; 9(10):e111318. PMID: 25347824; PMCID: PMC4210136.
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    134. Juang JM, Lu TP, Lai LC, Ho CC, Liu YB, Tsai CT, Lin LY, Yu CC, Chen WJ, Chiang FT, Yeh SF, Lai LP, Chuang EY, Lin JL. Disease-targeted sequencing of ion channel genes identifies de novo mutations in patients with non-familial Brugada syndrome. Sci Rep. 2014 Oct 23; 4:6733. PMID: 25339316; PMCID: PMC4206841.
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    135. Lin CY, Chen HJ, Huang CC, Lai LC, Lu TP, Tseng GC, Kuo TT, Kuok QY, Hsu JL, Sung SY, Hung MC, Sher YP. ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway. Cancer Res. 2014 Sep 15; 74(18):5229-43. PMID: 25060522.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    136. Lu TP, Chen KT, Tsai MH, Kuo KT, Hsiao CK, Lai LC, Chuang EY. Identification of genes with consistent methylation levels across different human tissues. Sci Rep. 2014 Mar 12; 4:4351. PMID: 24619003; PMCID: PMC3950633.
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    137. Juang JM, Lu TP, Lai LC, Hsueh CH, Liu YB, Tsai CT, Lin LY, Yu CC, Hwang JJ, Chiang FT, Yeh SS, Chen WP, Chuang EY, Lai LP, Lin JL. Utilizing multiple in silico analyses to identify putative causal SCN5A variants in Brugada syndrome. Sci Rep. 2014 Jan 27; 4:3850. PMID: 24463578; PMCID: PMC3902491.
      Citations:    
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