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JOUD HAJJAR

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
ORCID ORCID Icon0000-0003-4633-1043 Additional info
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    Collapse Biography 
    Collapse awards and honors
    2016The US Immunodeficiency Network travel grant
    2016 - 2019The US Immunodeficiency Network research award
    2016 - 2019The Immunodeficiency Foundation research award
    2018The Clinical immmunology scoiety travel grant
    2018The US Immunodeficiency Network travel grant
    2018 - 2019The Chao Physician Scientist award
    2018 - 2019The Jeffrey Modell Foundation
    2019TX TopDocs
    2019Castle Connolly’s Exceptional Women in Medicine
    2019Castle Connolly’s Top Doctor
    2020 - 2021Norton Rose Fulbright, BCM
    2021Castle Connolly’s Exceptional Women in Medicine
    2021TX Top Docs
    2020Castle Connolly’s Exceptional Women in Medicine
    2020TX Top Docs

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
         (Joud Hajjar)
    The US Immunodeficiency Network
    Persistent lung infections in patients with primary antibody deficiency
    Role: PI
         (Joud Hajjar)
    The Chao Physician-Scientist Aawrd
    Fatigue and Microbiome in common variable immunodeficiency
    Role: PI
         (Joud Hajjar)
    The Jeffrey Modell Foundation
    Improving the transition of children with Immunodeficiency to adult care
    Role: PI
         (Joud Hajjar)
    2020 Texas Medical Center Digestive Diseases Center Pilot/Feasibility Award.
    Immune Dysregulation and the microbiome in Common Variable Immunodeficiency
    Role: PI
         (Joud Hajjar)
    Immune Deficiency Foundation
    Clinical Correlates of Fatigue in common variable immunodeficiency
    Role: PI

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hajjar J, Derbala MH, Naing A. Unlocking the Potential of Anti-TIGIT Therapy-Between Promise and Challenges. JAMA Oncol. 2023 Nov 01; 9(11):1503-1504. PMID: 37768657.
      Citations:    Fields:    
    2. Stephen B, Hajjar J, Sarda S, Duose DY, Conroy JM, Morrison C, Alshawa A, Xu M, Zarifa A, Patel SP, Yuan Y, Kwiatkowski E, Wang L, Rodon Ahnert J, Fu S, Meric-Bernstam F, Lowman GM, Looney T, Naing A. T-cell receptor beta variable gene polymorphism predicts immune-related adverse events during checkpoint blockade immunotherapy. J Immunother Cancer. 2023 08; 11(8). PMID: 37604642; PMCID: PMC10445351.
      Citations: 3     Fields:    Translation:Humans
    3. Voigt A, Conner M, Swennes A, Fowler S, Calarge C, Mendonca D, Armstrong D, Chang CY, Walter J, Butte M, Savidge T, Oh J, Kheradmand F, Petrosino J, Hajjar J. Common Variable Immunodeficiency Patient Fecal Microbiota Transplant Recapitulates Gut Dysbiosis. Res Sq. 2023 Mar 13. PMID: 36993518; PMCID: PMC10055500.
      Citations:    
    4. Salih A, Chin A, Gandhi M, Shamshirsaz A, Lombaard H, Hajjar J. Hereditary angioedema and COVID-19 during pregnancy: Two case reports. J Allergy Clin Immunol Pract. 2023 03; 11(3):961-962. PMID: 36572180; PMCID: PMC9788987.
      Citations:    Fields:    Translation:Humans
    5. Ness TE, Erickson TA, Diaz V, Grimes AB, Rochat R, Anvari S, Hajjar J, Weatherhead J. Pediatric Eosinophilia: A Review and Multiyear Investigation into Etiologies. J Pediatr. 2023 02; 253:232-237.e1. PMID: 36195311.
      Citations:    Fields:    Translation:HumansCells
    6. Syed MN, Kutac C, Miller JM, Marsh R, Sullivan KE, Cunningham-Rundles C, Fuleihan RL, Kheradmand F, Hajjar J. Risk Factors of Pneumonia in Primary Antibody Deficiency Patients Receiving Immunoglobulin Therapy: Data from the US Immunodeficiency Network (USIDNET). J Clin Immunol. 2022 Oct; 42(7):1545-1552. PMID: 35779201.
      Citations:    Fields:    
    7. Perelygina L, Faisthalab R, Abernathy E, Chen MH, Hao L, Bercovitch L, Bayer DK, Noroski LM, Lam MT, Cicalese MP, Al-Herz W, Nanda A, Hajjar J, Vanden Driessche K, Schroven S, Leysen J, Rosenbach M, Abraham RS, Rangarjan HG, Buchbinder D, Kobrynski L, Pham-Huy A, Dhossche J, Cunningham Rundles C, Meyer AK, Theos A, Atkinson TP, Musiek A, Adeli M, Derichs U, Icenogle J, Sullivan KE, Peters P, Raedler J, Albert MH, Walz C, Kr?ger R, von Bernuth H, Klein C, Hauck F. Rubella Virus Infected Macrophages and Neutrophils Define Patterns of Granulomatous Inflammation in Inborn and Acquired Errors of Immunity. Front Immunol. 2021; 12:796065. PMID: 35003119; PMCID: PMC8728873.
      Citations: 2     Fields:    Translation:HumansCells
    8. Joshi TP, Anvari S, Gupta MR, Davis CM, Hajjar J. Case Report: Dupilumab Successfully Controls Severe Eczema in a Child With Elevated IgE Levels and Recurrent Skin Infections. Front Pediatr. 2021; 9:646997. PMID: 34660469; PMCID: PMC8511520.
      Citations: 1     
    9. Colen RR, Rolfo C, Ak M, Ayoub M, Ahmed S, Elshafeey N, Mamindla P, Zinn PO, Ng C, Vikram R, Bakas S, Peterson CB, Rodon Ahnert J, Subbiah V, Karp DD, Stephen B, Hajjar J, Naing A. Author response to Cunha et al. J Immunother Cancer. 2021 07; 9(7). PMID: 34315823; PMCID: PMC8317086.
      Citations:    Fields:    Translation:Humans
    10. Hajjar J. The immune system, cancer, and pathogens: It takes three to tango! J Immunother Precis Oncol. 2021 May; 4(2):33-34. PMID: 35663530; PMCID: PMC9153259.
      Citations:    
    11. Xu M, Tapia C, Hajjar J, Sabir S, Colen R, Nagarajan P, Aung PP, Gong J, Rodon J, Fu S, Stephen B, Roy-Chowdhuri S, Le H, Yang V, Zarifa A, Abdelsalam ME, Jhingran A, Javle M, Pant S, Carter B, Milton DR, Sun R, Karp DD, Koay EJ, Yang Y, Wistuba II, Hwu P, Meric-Bernstam F, Naing A. Implementation of a Novel Web-Based Lesion Selection Tool to Improve Acquisition of Tumor Biopsy Specimens. J Immunother Precis Oncol. 2021 May; 4(2):45-52. PMID: 35663531; PMCID: PMC9153261.
      Citations: 3     
    12. Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL, Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N. Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients. J Exp Med. 2021 07 05; 218(7). PMID: 33951726; PMCID: PMC8105723.
      Citations: 3     Fields:    Translation:HumansCells
    13. Colen RR, Rolfo C, Ak M, Ayoub M, Ahmed S, Elshafeey N, Mamindla P, Zinn PO, Ng C, Vikram R, Bakas S, Peterson CB, Rodon Ahnert J, Subbiah V, Karp DD, Stephen B, Hajjar J, Naing A. Radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers. J Immunother Cancer. 2021 04; 9(4). PMID: 33849924; PMCID: PMC8051405.
      Citations: 9     Fields:    Translation:Humans
    14. Hajjar J, Mendoza T, Zhang L, Fu S, Piha-Paul SA, Hong DS, Janku F, Karp DD, Ballhausen A, Gong J, Zarifa A, Peterson CB, Meric-Bernstam F, Jenq R, Naing A. Associations between the gut microbiome and fatigue in cancer patients. Sci Rep. 2021 03 12; 11(1):5847. PMID: 33712647; PMCID: PMC7954807.
      Citations: 7     Fields:    Translation:HumansCells
    15. . Case Report: Metastatic Dedifferentiated Liposarcoma Presenting as Hypereosinophilia in an Adolescent. Journal of Immunotherapy and Precision Oncology. 2021; 1(4):21-25. View Publication.
    16. Stephen B, Hajjar J. Immune System in Action. Adv Exp Med Biol. 2021; 1342:1-43. PMID: 34972961.
      Citations:    Fields:    Translation:HumansCells
    17. Naing A, Hajjar J, Gulley JL, Atkins MB, Ciliberto G, Meric-Bernstam F, Hwu P. Strategies for improving the management of immune-related adverse events. J Immunother Cancer. 2020 12; 8(2). PMID: 33310772; PMCID: PMC7735083.
      Citations: 19     Fields:    Translation:Humans
    18. Balasubramanyam S, Hajjar J. Case Report: Metastatic Dedifferentiated Liposarcoma Presenting as Hypereosinophilia in an Adolescent. J Immunother Precis Oncol. 2021 Feb; 4(1):21-25. PMID: 35664823; PMCID: PMC9161663.
      Citations:    
    19. Choi Y, Shi Y, Haymaker CL, Naing A, Ciliberto G, Hajjar J. T-cell agonists in cancer immunotherapy. J Immunother Cancer. 2020 10; 8(2). PMID: 33020242; PMCID: PMC7537335.
      Citations: 17     Fields:    Translation:HumansCells
    20. Jiang Y, Firan M, Nandiwada SL, Reyes A, Marsh RA, Vogel TP, Hajjar J. The Natural History of X-Linked Lymphoproliferative Disease (XLP1): Lessons from a Long-Term Survivor. Case Reports Immunol. 2020; 2020:8841571. PMID: 32908732; PMCID: PMC7474360.
      Citations: 3     
    21. Tapia C, Aung PP, Roy-Chowdhuri S, Xu M, Ouyang F, Alshawa A, Hajjar J, Singh G, Yang V, Castillo L, Le H, Murthy R, Stephen B, Hess KR, Wistuba I, Naing A. Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors. J Immunother Cancer. 2020 04; 8(1). PMID: 32303619; PMCID: PMC7204618.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    22. Adashek JJ, Hajjar J, Chemaly RF, Kurzrock R. Are Cancer Patients at Higher Risk of Death With COVID-19? J Immunother Precis Oncol. 2020 May; 3(2):49-51. PMID: 34532715; PMCID: PMC8442944.
      Citations: 2     
    23. Naing A, Meric-Bernstam F, Stephen B, Karp DD, Hajjar J, Rodon Ahnert J, Piha-Paul SA, Colen RR, Jimenez C, Raghav KP, Ferrarotto R, Tu SM, Campbell M, Wang L, Sabir SH, Tapia C, Bernatchez C, Frumovitz M, Tannir N, Ravi V, Khan S, Painter JM, Abonofal A, Gong J, Alshawa A, McQuinn LM, Xu M, Ahmed S, Subbiah V, Hong DS, Pant S, Yap TA, Tsimberidou AM, Dumbrava EEI, Janku F, Fu S, Simon RM, Hess KR, Varadhachary GR, Habra MA. Phase 2 study of pembrolizumab in patients with advanced rare cancers. J Immunother Cancer. 2020 03; 8(1). PMID: 32188704; PMCID: PMC7078933.
      Citations: 32     Fields:    Translation:HumansCTClinical Trials
    24. Stephen B, Hajjar J. Overview of Basic Immunology and Clinical Application. Adv Exp Med Biol. 2020; 1244:1-36. PMID: 32301008.
      Citations: 3     Fields:    Translation:Humans
    25. Nguyen AL, Constantine G, Kutac C, Syed MN, Orange JS, Sullivan KE. Prophylactic Antibiotics Versus Immunoglobulin Replacement in Specific Antibody Deficiency. J Clin Immunol. 2020 01; 40(1):158-164. PMID: 31758281.
      Citations: 4     Fields:    Translation:Humans
    26. Chinn IK, Chan AY, Chen K, Chou J, Dorsey MJ, Hajjar J, Jongco AM, Keller MD, Kobrynski LJ, Kumanovics A, Lawrence MG, Leiding JW, Lugar PL, Orange JS, Patel K, Platt CD, Puck JM, Raje N, Romberg N, Slack MA, Sullivan KE, Tarrant TK, Torgerson TR, Walter JE. Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: A?working group report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol. 2020 01; 145(1):46-69. PMID: 31568798.
      Citations: 19     Fields:    Translation:Humans
    27. . Cancer Immunotherapy for the Immunosuppressed: Dissecting the Conundrum of Safety and Efficacy. Editorial. 2019. View Publication.
    28. Noroski L, Das S, Hajjar J. Case 40-2018: A Woman with Recurrent Sinusitis, Cough, and Bronchiectasis. N Engl J Med. 2019 04 04; 380(14):1383. PMID: 30943358.
      Citations:    Fields:    Translation:Humans
    29. Hajjar J, Kutac C, Rider NL, Seeborg FO, Scalchunes C, Orange J. Fatigue and the wear-off effect in adult patients with common variable immunodeficiency. Clin Exp Immunol. 2018 12; 194(3):327-338. PMID: 30168848; PMCID: PMC6231022.
      Citations: 6     Fields:    Translation:Humans
    30. Tuano KTS, Anvari S, Hanson IC, Hajjar J, Seeborg F, Noroski LM, Guffey D, Kang G, Orange JS, Davis CM. Improved diagnostic clarity in shrimp allergic non-dust-mite sensitized patients. Allergy Asthma Proc. 2018 Sep 01; 39(5):377-383. PMID: 30153888; PMCID: PMC6122289.
      Citations: 4     Fields:    Translation:HumansAnimals
    31. Fujii T, Naing A, Rolfo C, Hajjar J. Biomarkers of response to immune checkpoint blockade in cancer treatment. Crit Rev Oncol Hematol. 2018 Oct; 130:108-120. PMID: 30196907.
      Citations: 29     Fields:    Translation:Humans
    32. Hajjar J, Al-Kaabi A, Kutac C, Dunn J, Shearer WT, Orange JS. Questioning the accuracy of currently available pneumococcal antibody testing. J Allergy Clin Immunol. 2018 10; 142(4):1358-1360. PMID: 29936105.
      Citations: 5     Fields:    Translation:HumansCells
    33. Heimall JR, Hagin D, Hajjar J, Henrickson SE, Hernandez-Trujillo HS, Itan Y, Kobrynski L, Paris K, Torgerson TR, Verbsky JW, Wasserman RL, Hsieh EWY, Bleesing JJ, Chou JS, Lawrence MG, Marsh RA, Rosenzweig SD, Orange JS, Abraham RS. Correction to: Use of Genetic Testing for Primary Immunodeficiency Patients. J Clin Immunol. 2018 May; 38(4):540-541. PMID: 29781065.
      Citations:    Fields:    
    34. . Latent therapeutic demand model for the immunoglobulin replacement therapy of primary immune deficiency disorders in the USA. Latent therapeutic demand model for the immunoglobulin replacement therapy of primary immune deficiency disorders in the USA. 2018. View Publication.
    35. Stonebraker JS, Hajjar J, Orange JS. Latent therapeutic demand model for the immunoglobulin replacement therapy of primary immune deficiency disorders in the USA. Vox Sang. 2018 Apr 20. PMID: 29675923.
      Citations: 2     Fields:    
    36. Heimall JR, Hagin D, Hajjar J, Henrickson SE, Hernandez-Trujillo HS, Tan Y, Kobrynski L, Paris K, Torgerson TR, Verbsky JW, Wasserman RL, Hsieh EWY, Blessing JJ, Chou JS, Lawrence MG, Marsh RA, Rosenzweig SD, Orange JS, Abraham RS. Use of Genetic Testing for Primary Immunodeficiency Patients. J Clin Immunol. 2018 04; 38(3):320-329. PMID: 29675737.
      Citations: 23     Fields:    Translation:Humans
    37. Stephen B, Hajjar J. Overview of Basic Immunology and Translational Relevance for Clinical Investigators. Adv Exp Med Biol. 2018; 995:1-41. PMID: 30539504.
      Citations: 1     Fields:    Translation:HumansCells
    38. Fujii T, Colen RR, Bilen MA, Hess KR, Hajjar J, Suarez-Almazor ME, Alshawa A, Hong DS, Tsimberidou A, Janku F, Gong J, Stephen B, Subbiah V, Piha-Paul SA, Fu S, Sharma P, Mendoza T, Patel A, Thirumurthi S, Sheshadri A, Meric-Bernstam F, Naing A. Incidence of immune-related adverse events and its association with treatment outcomes: the MD Anderson Cancer Center experience. Invest New Drugs. 2018 08; 36(4):638-646. PMID: 29159766; PMCID: PMC5962379.
      Citations: 58     Fields:    Translation:Humans
    39. Colen RR, Fujii T, Bilen MA, Kotrotsou A, Abrol S, Hess KR, Hajjar J, Suarez-Almazor ME, Alshawa A, Hong DS, Giniebra-Camejo D, Stephen B, Subbiah V, Sheshadri A, Mendoza T, Fu S, Sharma P, Meric-Bernstam F, Naing A. Radiomics to predict immunotherapy-induced pneumonitis: proof of concept. Invest New Drugs. 2018 08; 36(4):601-607. PMID: 29075985; PMCID: PMC5924418.
      Citations: 40     Fields:    Translation:Humans
    40. Hajjar J, Restrepo A, Javeri H, Wiederhold NP, Papanastassiou AM, Patterson TF. Multiple Brain Abscesses Caused by Trichosporon inkin in a Patient with X-Linked Chronic Granulomatous Disease (CGD) Successfully Treated with Antifungal Therapy. J Clin Immunol. 2017 08; 37(6):519-523. PMID: 28698914.
      Citations:    Fields:    Translation:HumansAnimals
    41. Rider NL, Kutac C, Hajjar J, Scalchunes C, Seeborg FO, Boyle M, Orange JS. Health-Related Quality of Life in Adult Patients with Common Variable Immunodeficiency Disorders and Impact of Treatment. J Clin Immunol. 2017 Jul; 37(5):461-475. PMID: 28536745; PMCID: PMC5489588.
      Citations: 28     Fields:    Translation:Humans
    42. Hajjar J, Guffey D, Minard CG, Orange JS. Increased Incidence of Fatigue in Patients with Primary Immunodeficiency Disorders: Prevalence and Associations Within the US Immunodeficiency Network Registry. J Clin Immunol. 2017 Feb; 37(2):153-165. PMID: 28124237; PMCID: PMC5326589.
      Citations: 14     Fields:    Translation:HumansCells
    43. Stephen B, Hajjar J. Overview of Basic Immunology for Clinical Investigators. Adv Exp Med Biol. 2017; 995:1-31. PMID: 28321810.
      Citations:    Fields:    Translation:HumansAnimalsCells
    44. Bupathi M, Hajjar J, Bean S, Fu S, Hong D, Karp D, Stephen B, Hess K, Meric-Bernstam F, Naing A. Incidence of infusion reactions to anti-neoplastic agents in early phase clinical trials: The MD Anderson Cancer Center experience. Invest New Drugs. 2017 02; 35(1):59-67. PMID: 27687047; PMCID: PMC5896759.
      Citations: 1     Fields:    Translation:Humans
    45. Hajjar J, Hasan S, Forbes LR, Hemmige V, Orange JS. Gastric Adenocarcinoma in a Patient with X-Linked Agammaglobulinemia and HIV: Case Report and Review of the Literature. Front Pediatr. 2016; 4:100. PMID: 27722150; PMCID: PMC5033959.
      Citations: 2     
    46. Quinti I, Pulvirenti F, Giannantoni P, Hajjar J, Canter DL, Milito C, Abeni D, Orange JS, Tabolli S. Development and Initial Validation of a Questionnaire to Measure Health-Related Quality of Life of Adults with Common Variable Immune Deficiency: The CVID_QoL Questionnaire. J Allergy Clin Immunol Pract. 2016 Nov - Dec; 4(6):1169-1179.e4. PMID: 27665385.
      Citations: 14     Fields:    Translation:Humans
    47. Moon YW, Hajjar J, Hwu P, Naing A. Targeting the indoleamine 2,3-dioxygenase pathway in cancer. J Immunother Cancer. 2015; 3:51. PMID: 26674411; PMCID: PMC4678703.
      Citations: 128     Fields:    
    48. Hajjar J, Habra MA, Naing A. Metformin: an old drug with new potential. Expert Opin Investig Drugs. 2013 Dec; 22(12):1511-7. PMID: 23978196.
      Citations: 14     Fields:    Translation:HumansAnimals
    49. Najm S, Hajjar J, Nelson RP, Moorthy RS, Wolf KM, Lahm T. Whipple's disease-associated pulmonary hypertension with positive vasodilator response despite severe hemodynamic derangements. Can Respir J. 2011 Sep-Oct; 18(5):e70-2. PMID: 21969933; PMCID: PMC3267610.
      Citations: 2     Fields:    Translation:Humans
    50. Petrache I, Hajjar J, Campos M. Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency. Biologics. 2009; 3:193-204. PMID: 19707408; PMCID: PMC2726081.
      Citations: 33     
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