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JIZHONG CHENG

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Nephrology
AddressONE BAYLOR PLAZA
HOUSTON TX 77030
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    Collapse Research 
    Collapse research activities and funding
    R01DK095867     (CHENG, JIZHONG)Mar 15, 2013 - Jan 31, 2018
    NIH/NIDDK
    CHRONIC KIDNEY DISEASE ADVERSELY INFLUENCES VASCULAR FUNCTIONS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Liang M, Guo Q, Huang F, Han G, Song K, Luo J, Cheng H, Hu H, Peden EK, Chen C, Mitch WE, Du J, Fu X, Truong L, Cheng J. Notch signaling in bone marrow-derived FSP-1 cells initiates neointima formation in arteriovenous fistulas. Kidney Int. 2019 Feb 16. PMID: 30799025.
      View in: PubMed
    2. Wang W, Wang Z, Tian D, Zeng X, Liu Y, Fu Q, Liang A, Zhang Y, Gao Q, Cheng J, Wang Y. Integrin ß3 Mediates the Endothelial-to-Mesenchymal Transition via the Notch Pathway. Cell Physiol Biochem. 2018; 49(3):985. PMID: 30196283.
      View in: PubMed
    3. Luo J, Liang A, Liang M, Xia R, Rizvi Y, Wang Y, Cheng J. Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3. J Am Soc Nephrol. 2016 09; 27(9):2797-808. PMID: 26880799.
      View in: PubMed
    4. Dong Y, Yang M, Zhang J, Peng X, Cheng J, Cui T, Du J. Depletion of CD8+ T Cells Exacerbates CD4+ T Cell-Induced Monocyte-to-Fibroblast Transition in Renal Fibrosis. J Immunol. 2016 Feb 15; 196(4):1874-81. PMID: 26773152.
      View in: PubMed
    5. Liu Y, Wang Y, Shi H, Jia L, Cheng J, Cui W, Li H, Li P, Du J. CARD9 mediates necrotic smooth muscle cell-induced inflammation in macrophages contributing to neointima formation of vein grafts. Cardiovasc Res. 2015 Oct 01; 108(1):148-58. PMID: 26243429.
      View in: PubMed
    6. Liang M, Wang Y, Liang A, Mitch WE, Roy-Chaudhury P, Han G, Cheng J. Migration of smooth muscle cells from the arterial anastomosis of arteriovenous fistulas requires Notch activation to form neointima. Kidney Int. 2015 Sep; 88(3):490-502. PMID: 25786100.
      View in: PubMed
    7. Luo J, Liang M, Mitch WE, Danesh FR, Yu M, Cheng J. FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice. Endocrinology. 2015 Jun; 156(6):2200-10. PMID: 25774552.
      View in: PubMed
    8. Liang M, Woodard LE, Liang A, Luo J, Wilson MH, Mitch WE, Cheng J. Protective role of insulin-like growth factor-1 receptor in endothelial cells against unilateral ureteral obstruction-induced renal fibrosis. Am J Pathol. 2015 May; 185(5):1234-50. PMID: 25783760.
      View in: PubMed
    9. Liang M, Wang Y, Liang A, Dong JF, Du J, Cheng J. Impaired integrin ß3 delays endothelial cell regeneration and contributes to arteriovenous graft failure in mice. Arterioscler Thromb Vasc Biol. 2015 Mar; 35(3):607-15. PMID: 25614287.
      View in: PubMed
    10. Liang M, Liang A, Wang Y, Jiang J, Cheng J. Smooth muscle cells from the anastomosed artery are the major precursors for neointima formation in both artery and vein grafts. Basic Res Cardiol. 2014; 109(5):431. PMID: 25107324.
      View in: PubMed
    11. Wang Y, Liang A, Luo J, Liang M, Han G, Mitch WE, Cheng J. Blocking Notch in endothelial cells prevents arteriovenous fistula failure despite CKD. J Am Soc Nephrol. 2014 Apr; 25(4):773-83. PMID: 24480830.
      View in: PubMed
    12. Liang A, Wang Y, Han G, Truong L, Cheng J. Chronic kidney disease accelerates endothelial barrier dysfunction in a mouse model of an arteriovenous fistula. Am J Physiol Renal Physiol. 2013 Jun 15; 304(12):F1413-20. PMID: 23576636.
      View in: PubMed
    13. Liang A, Wang Y, Woodard LE, Wilson MH, Sharma R, Awasthi YC, Du J, Mitch WE, Cheng J. Loss of glutathione S-transferase A4 accelerates obstruction-induced tubule damage and renal fibrosis. J Pathol. 2012 Dec; 228(4):448-58. PMID: 22711583.
      View in: PubMed
    14. Ma F, Li Y, Jia L, Han Y, Cheng J, Li H, Qi Y, Du J. Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF ß/Smad activation and cardiac fibrosis induced by angiotensin II. PLoS One. 2012; 7(5):e35144. PMID: 22574112.
      View in: PubMed
    15. Yang M, Zheng J, Miao Y, Wang Y, Cui W, Guo J, Qiu S, Han Y, Jia L, Li H, Cheng J, Du J. Serum-glucocorticoid regulated kinase 1 regulates alternatively activated macrophage polarization contributing to angiotensin II-induced inflammation and cardiac fibrosis. Arterioscler Thromb Vasc Biol. 2012 Jul; 32(7):1675-86. PMID: 22556335.
      View in: PubMed
    16. Li Y, Zhang C, Wu Y, Han Y, Cui W, Jia L, Cai L, Cheng J, Li H, Du J. Interleukin-12p35 deletion promotes CD4 T-cell-dependent macrophage differentiation and enhances angiotensin II-Induced cardiac fibrosis. Arterioscler Thromb Vasc Biol. 2012 Jul; 32(7):1662-74. PMID: 22556333.
      View in: PubMed
    17. Pan L, Li Y, Jia L, Qin Y, Qi G, Cheng J, Qi Y, Li H, Du J. Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances Ang II-induced cardiac inflammation. PLoS One. 2012; 7(4):e35315. PMID: 22558139.
      View in: PubMed
    18. Zhang L, Dong Y, Dong Y, Cheng J, Du J. Role of integrin-ß3 protein in macrophage polarization and regeneration of injured muscle. J Biol Chem. 2012 Feb 24; 287(9):6177-86. PMID: 22210777.
      View in: PubMed
    19. Cheng J, Wang Y, Liang A, Jia L, Du J. FSP-1 silencing in bone marrow cells suppresses neointima formation in vein graft. Circ Res. 2012 Jan 20; 110(2):230-40. PMID: 22116816.
      View in: PubMed
    20. Qi G, Jia L, Li Y, Bian Y, Cheng J, Li H, Xiao C, Du J. Angiotensin II infusion-induced inflammation, monocytic fibroblast precursor infiltration, and cardiac fibrosis are pressure dependent. Cardiovasc Toxicol. 2011 Jun; 11(2):157-67. PMID: 21373977.
      View in: PubMed
    21. Ren J, Yang M, Qi G, Zheng J, Jia L, Cheng J, Tian C, Li H, Lin X, Du J. Proinflammatory protein CARD9 is essential for infiltration of monocytic fibroblast precursors and cardiac fibrosis caused by Angiotensin II infusion. Am J Hypertens. 2011 Jun; 24(6):701-7. PMID: 21436792.
      View in: PubMed
    22. Cheng J, Wang Y, Ma Y, Chan BT, Yang M, Liang A, Zhang L, Li H, Du J. The mechanical stress-activated serum-, glucocorticoid-regulated kinase 1 contributes to neointima formation in vein grafts. Circ Res. 2010 Nov 12; 107(10):1265-74. PMID: 20884880.
      View in: PubMed
    23. Cheng J, Truong LD, Wu X, Kuhl D, Lang F, Du J. Serum- and glucocorticoid-regulated kinase 1 is upregulated following unilateral ureteral obstruction causing epithelial-mesenchymal transition. Kidney Int. 2010 Oct; 78(7):668-78. PMID: 20631674.
      View in: PubMed
    24. Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, Trial J, Taffet GE, Entman ML. Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol. 2010 Sep; 49(3):499-507. PMID: 20488188.
      View in: PubMed
    25. Wu X, Cheng J, Li P, Yang M, Qiu S, Liu P, Du J. Mechano-sensitive transcriptional factor Egr-1 regulates insulin-like growth factor-1 receptor expression and contributes to neointima formation in vein grafts. Arterioscler Thromb Vasc Biol. 2010 Mar; 30(3):471-6. PMID: 19965784.
      View in: PubMed
    26. Cheng J, Zhang J, Merched A, Zhang L, Zhang P, Truong L, Boriek AM, Du J. Mechanical stretch inhibits oxidized low density lipoprotein-induced apoptosis in vascular smooth muscle cells by up-regulating integrin alphavbeta3 and stablization of PINCH-1. J Biol Chem. 2007 Nov 23; 282(47):34268-75. PMID: 17878168.
      View in: PubMed
    27. Cheng J, Du J. Mechanical stretch simulates proliferation of venous smooth muscle cells through activation of the insulin-like growth factor-1 receptor. Arterioscler Thromb Vasc Biol. 2007 Aug; 27(8):1744-51. PMID: 17541019.
      View in: PubMed
    28. Cheng J, Cui R, Chen CH, Du J. Oxidized low-density lipoprotein stimulates p53-dependent activation of proapoptotic Bax leading to apoptosis of differentiated endothelial progenitor cells. Endocrinology. 2007 May; 148(5):2085-94. PMID: 17289842.
      View in: PubMed
    29. Ma Y, Zhang L, Peng T, Cheng J, Taneja S, Zhang J, Delafontaine P, Du J. Angiotensin II stimulates transcription of insulin-like growth factor I receptor in vascular smooth muscle cells: role of nuclear factor-kappaB. Endocrinology. 2006 Mar; 147(3):1256-63. PMID: 16322063.
      View in: PubMed
    30. Zhang L, Cheng J, Ma Y, Thomas W, Zhang J, Du J. Dual pathways for nuclear factor kappaB activation by angiotensin II in vascular smooth muscle: phosphorylation of p65 by IkappaB kinase and ribosomal kinase. Circ Res. 2005 Nov 11; 97(10):975-82. PMID: 16224066.
      View in: PubMed
    31. Zhang L, Ma Y, Zhang J, Cheng J, Du J. A new cellular signaling mechanism for angiotensin II activation of NF-kappaB: An IkappaB-independent, RSK-mediated phosphorylation of p65. Arterioscler Thromb Vasc Biol. 2005 Jun; 25(6):1148-53. PMID: 15802625.
      View in: PubMed
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