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HORACIO J ADROGUE

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Nephrology
Address7200 Cambridge St
8th Floor
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Adrogué HJ, Madias NE. Sodium surfeit and potassium deficit: keys to the pathogenesis of hypertension. J Am Soc Hypertens. 2014 Mar; 8(3):203-13. PMID: 24200471.
      View in: PubMed
    2. Raimondi GA, Gonzalez S, Zaltsman J, Menga G, Adrogué HJ. Acid-base patterns in acute severe asthma. J Asthma. 2013 Dec; 50(10):1062-8. PMID: 23947392.
      View in: PubMed
    3. Adrogué HJ, Madias NE. The challenge of hyponatremia. J Am Soc Nephrol. 2012 Jul; 23(7):1140-8. PMID: 22626822.
      View in: PubMed
    4. Adrogué HJ. Diagnosis and management of severe respiratory acidosis: a 65-year-old man with a double-lung transplant and shortness of breath. Am J Kidney Dis. 2010 Nov; 56(5):994-1000. PMID: 20673604.
      View in: PubMed
    5. Adrogué HJ, Madias NE. Secondary responses to altered acid-base status: the rules of engagement. J Am Soc Nephrol. 2010 Jun; 21(6):920-3. PMID: 20431042.
      View in: PubMed
    6. Adrogué HJ, Gennari FJ, Galla JH, Madias NE. Assessing acid-base disorders. Kidney Int. 2009 Dec; 76(12):1239-47. PMID: 19812535.
      View in: PubMed
    7. Adrogué HJ, Madias NE. Shared primacy of sodium and potassium on cardiovascular risk. Am J Kidney Dis. 2009 Oct; 54(4):598-601. PMID: 19577349.
      View in: PubMed
    8. Levy Yeyati N, Fellet A, Arranz C, Balaszczuk AM, Adrogué HJ. Amiloride-sensitive and amiloride-insensitive kaliuresis in advanced chronic kidney disease. J Nephrol. 2008 Jan-Feb; 21(1):93-8. PMID: 18264941.
      View in: PubMed
    9. Wang W, Soltero L, Zhang P, Huang XR, Lan HY, Adrogue HJ. Renal inflammation is modulated by potassium in chronic kidney disease: possible role of Smad7. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1123-30. PMID: 17634402.
      View in: PubMed
    10. Adrogué HJ, Madias NE. Sodium and potassium in the pathogenesis of hypertension. N Engl J Med. 2007 May 10; 356(19):1966-78. PMID: 17494929.
      View in: PubMed
    11. Locatelli F, Villa G, de Francisco AL, Albertazzi A, Adrogue HJ, Dougherty FC, Beyer U. Effect of a continuous erythropoietin receptor activator (C.E.R.A.) on stable haemoglobin in patients with CKD on dialysis: once monthly administration. Curr Med Res Opin. 2007 May; 23(5):969-79. PMID: 17519064.
      View in: PubMed
    12. Adrogué HJ. Mixed acid-base disturbances. J Nephrol. 2006 Mar-Apr; 19 Suppl 9:S97-103. PMID: 16736447.
      View in: PubMed
    13. Adrogué HJ. Metabolic acidosis: pathophysiology, diagnosis and management. J Nephrol. 2006 Mar-Apr; 19 Suppl 9:S62-9. PMID: 16736443.
      View in: PubMed
    14. Adrogué HJ. Consequences of inadequate management of hyponatremia. Am J Nephrol. 2005 May-Jun; 25(3):240-9. PMID: 15914973.
      View in: PubMed
    15. Frangiosa A, De Santo LS, Saviano C, Anastasio P, Cotrufo M, Capasso G, Adrogue HJ, De Santo NG. The effect of oral protein loading on renal acidification in patients with heart failure. J Nephrol. 2005 May-Jun; 18(3):294-302. PMID: 16013018.
      View in: PubMed
    16. Adrogué HJ, Madias NE. PCO2 and [K+]p in metabolic acidosis: certainty for the first and uncertainty for the other. J Am Soc Nephrol. 2004 Jun; 15(6):1667-8. PMID: 15153580.
      View in: PubMed
    17. Dolson GM, Ellis KJ, Johnson ML, Adrogué HJ. Incidence and consequences of total body potassium depletion in chronic hemodialysis patients. Front Biosci. 2003 May 1; 8:a126-32. PMID: 12700088.
      View in: PubMed
    18. Madias NE, Adrogué HJ. Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Nephron Physiol. 2003; 93(3):p61-6. PMID: 12660492.
      View in: PubMed
    19. Frangiosa A, De Santo LS, De Santo NG, Anastasio P, Favazzi P, Cirillo E, Cotrufo M, Adroguè HJ. Acid-base state in patients after cardiac transplantation. Am J Nephrol. 2002 Jul-Aug; 22(4):332-7. PMID: 12169864.
      View in: PubMed
    20. Pressel S, Davis BR, Louis GT, Whelton P, Adrogue H, Egan D, Farber M, Payne G, Probstfield J, Ward H. Participant recruitment in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Control Clin Trials. 2001 Dec; 22(6):674-86. PMID: 11738123.
      View in: PubMed
    21. Adrogué HE, Adrogué HJ. Acid-base physiology. Respir Care. 2001 Apr; 46(4):328-41. PMID: 11345941.
      View in: PubMed
    22. Adrogué HJ, Madias NE. Hyponatremia. N Engl J Med. 2000 May 25; 342(21):1581-9. PMID: 10824078.
      View in: PubMed
    23. Adrogué HJ, Madias NE. Hypernatremia. N Engl J Med. 2000 May 18; 342(20):1493-9. PMID: 10816188.
      View in: PubMed
    24. Dolson GM, Adrogué HJ. Low dialysate [K+] decreases efficiency of hemodialysis and increases urea rebound. J Am Soc Nephrol. 1998 Nov; 9(11):2124-8. PMID: 9808100.
      View in: PubMed
    25. Adrogué HJ, Madias NE. Management of life-threatening acid-base disorders. Second of two parts. N Engl J Med. 1998 Jan 8; 338(2):107-11. PMID: 9420343.
      View in: PubMed
    26. Adrogué HJ, Madias NE. Management of life-threatening acid-base disorders. First of two parts. N Engl J Med. 1998 Jan 1; 338(1):26-34. PMID: 9414329.
      View in: PubMed
    27. Adrogué HJ, Madias NE. Aiding fluid prescription for the dysnatremias. Intensive Care Med. 1997 Mar; 23(3):309-16. PMID: 9083234.
      View in: PubMed
    28. Hricik DE, Levine BS, Adrogue HJ, Weinberg MS, Goldstein R. Evaluation of enalapril/diltiazem ER in hypertensive patients with coexisting renal dysfunction. Enalapril/Diltiazem ER in Hypertensive Renal Disease Group. J Hum Hypertens. 1996 Nov; 10(11):769-74. PMID: 9004108.
      View in: PubMed
    29. Adrogue HJ, Pena J, Comstock JP. Glyburide increases the secretion, tissue uptake, and action of insulin in conscious normal dogs. Metabolism. 1996 May; 45(5):579-86. PMID: 8622600.
      View in: PubMed
    30. Adrogué HJ, Wesson DE. Role of dietary factors in the hypertension of African Americans. Semin Nephrol. 1996 Mar; 16(2):94-101. PMID: 8668865.
      View in: PubMed
    31. Yeyati NL, Adrogué HJ. Inappropriately high plasma renin activity accompanies chronic loss of renal function. Am J Nephrol. 1996; 16(6):471-7. PMID: 8955757.
      View in: PubMed
    32. Okuda Y, Adrogue HJ, Nakajima T, Mizutani M, Asano M, Tachi Y, Suzuki S, Yamashita K. Increased production of PDGF by angiotensin and high glucose in human vascular endothelium. Life Sci. 1996; 59(17):1455-61. PMID: 8890924.
      View in: PubMed
    33. Okuda Y, Adrogue HJ, Field JB, Nohara H, Yamashita K. Counterproductive effects of sodium bicarbonate in diabetic ketoacidosis. J Clin Endocrinol Metab. 1996 Jan; 81(1):314-20. PMID: 8550770.
      View in: PubMed
    34. Dolson GM, Wesson DE, Adrogué HJ. Vascular relaxation probably mediates the antihypertensive effect of a high-potassium diet: a role for enhanced vascular Na,K-ATPase activity. J Hypertens. 1995 Dec; 13(12 Pt 1):1433-9. PMID: 8866905.
      View in: PubMed
    35. Dolson GM, Ellis KJ, Bernardo MV, Prakash R, Adrogué HJ. Acute decreases in serum potassium augment blood pressure. Am J Kidney Dis. 1995 Aug; 26(2):321-6. PMID: 7645536.
      View in: PubMed
    36. Dolson GM, Ribeiro C, Ulate G, Ribeiro-Neto F, Adrogué HJ. Identification of GTP-binding proteins in turtle urinary bladder epithelial cells. Miner Electrolyte Metab. 1994; 20(5):302-8. PMID: 7700219.
      View in: PubMed
    37. Dolson GM, Schwarze KD, Prabhakar S, Adrogué HJ. Demonstration of an apical chloride conductive pathway in granular cells of toad urinary bladder. Miner Electrolyte Metab. 1993; 19(1):39-46. PMID: 8393960.
      View in: PubMed
    38. Adrogué HJ. Glucose homeostasis and the kidney. Kidney Int. 1992 Nov; 42(5):1266-82. PMID: 1453613.
      View in: PubMed
    39. Yeyati NL, Altenberg GA, Adrogué HJ. Mechanism of acetazolamide-induced rise in renal vascular resistance assessed in the dog whole kidney. Ren Physiol Biochem. 1992 Mar-Apr; 15(2):99-105. PMID: 1375769.
      View in: PubMed
    40. Yeyati NL, Etcheverry JC, Adrogué HJ. Kaliuretic response to potassium loading in amiloride-treated dogs. Ren Physiol Biochem. 1990 Jul-Aug; 13(4):190-9. PMID: 1691859.
      View in: PubMed
    41. Madias NE, Cohen JJ, Adrogué HJ. Influence of acute and chronic respiratory alkalosis on preexisting chronic metabolic alkalosis. Am J Physiol. 1990 Mar; 258(3 Pt 2):F479-85. PMID: 2107757.
      View in: PubMed
    42. Adrogué HJ, Rashad MN, Gorin AB, Yacoub J, Madias NE. Arteriovenous acid-base disparity in circulatory failure: studies on mechanism. Am J Physiol. 1989 Dec; 257(6 Pt 2):F1087-93. PMID: 2513727.
      View in: PubMed
    43. Adrogué HJ, Barrero J, Eknoyan G. Salutary effects of modest fluid replacement in the treatment of adults with diabetic ketoacidosis. Use in patients without extreme volume deficit. JAMA. 1989 Oct 20; 262(15):2108-13. PMID: 2507798.
      View in: PubMed
    44. Adrogué HJ, Rashad MN, Gorin AB, Yacoub J, Madias NE. Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood. N Engl J Med. 1989 May 18; 320(20):1312-6. PMID: 2535633.
      View in: PubMed
    45. Adrogué HJ, Barrero J, Ryan JE, Dolson GM. Diabetic ketoacidosis: a practical approach. Hosp Pract (Off Ed). 1989 Feb 15; 24(2):83-4, 90, 95-8 passim. PMID: 2493022.
      View in: PubMed
    46. Adrogué HJ, Chap Z, Okuda Y, Michael L, Hartley C, Entman M, Field JB. Acidosis-induced glucose intolerance is not prevented by adrenergic blockade. Am J Physiol. 1988 Dec; 255(6 Pt 1):E812-23. PMID: 3144181.
      View in: PubMed
    47. Adrogué HJ, Tasby J, Ulate G. Marginal effect of changes in acid-base status in vitro on rheogenic H+ and HCO3- secretion in turtle urinary bladder. Ren Physiol. 1987; 10(2):69-84. PMID: 2833810.
      View in: PubMed
    48. Adrogué HJ, Lederer ED, Suki WN, Eknoyan G. Determinants of plasma potassium levels in diabetic ketoacidosis. Medicine (Baltimore). 1986 May; 65(3):163-72. PMID: 3084904.
      View in: PubMed
    49. Adrogué HJ, Madias NE. Renal acidification during chronic hypercapnia in the conscious dog. Pflugers Arch. 1986 May; 406(5):520-8. PMID: 3714450.
      View in: PubMed
    50. Adrogué HJ, Madias NE. Influence of chronic respiratory acid-base disorders on acute CO2 titration curve. J Appl Physiol (1985). 1985 Apr; 58(4):1231-8. PMID: 3921516.
      View in: PubMed
    51. Adrogué HJ, Chap Z, Ishida T, Field JB. Role of the endocrine pancreas in the kalemic response to acute metabolic acidosis in conscious dogs. J Clin Invest. 1985 Mar; 75(3):798-808. PMID: 3884666; PMCID: PMC423607.
      View in: PubMed, PubMed Central
    52. Adrogué HJ, Tasby J, Suki WN. Simultaneous measurement of metabolic carbon dioxide production and carbon dioxide tension in the renal cortex. Trans Assoc Am Physicians. 1985; 98:74-84. PMID: 3939505.
      View in: PubMed
    53. Madias NE, Bossert WH, Adrogué HJ. Ventilatory response to chronic metabolic acidosis and alkalosis in the dog. J Appl Physiol Respir Environ Exerc Physiol. 1984 Jun; 56(6):1640-6. PMID: 6735822.
      View in: PubMed
    54. Adrogué HJ, Eknoyan G, Suki WK. Diabetic ketoacidosis: role of the kidney in the acid-base homeostasis re-evaluated. Kidney Int. 1984 Apr; 25(4):591-8. PMID: 6434787.
      View in: PubMed
    55. Madias NE, Adrogué HJ. Influence of chronic metabolic acid-base disorders on the acute CO2 titration curve. J Appl Physiol Respir Environ Exerc Physiol. 1983 Oct; 55(4):1187-95. PMID: 6415015.
      View in: PubMed
    56. Adrogué HJ, Brensilver J, Cohen JJ, Madias NE. Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog. J Clin Invest. 1983 Apr; 71(4):867-83. PMID: 6300190; PMCID: PMC436944.
      View in: PubMed, PubMed Central
    57. Adrogué HJ, Stinebaugh BJ, Gougoux A, Lemieux G, Vinay P, Tam SC, Goldstein MB, Halperin ML. Decreased distal acidification in acute hypercapnia in the dog. Am J Physiol. 1983 Jan; 244(1):F19-27. PMID: 6295183.
      View in: PubMed
    58. Adrogué HJ, Wilson H, Boyd AE, Suki WN, Eknoyan G. Plasma acid-base patterns in diabetic ketoacidosis. N Engl J Med. 1982 Dec 23; 307(26):1603-10. PMID: 6815530.
      View in: PubMed
    59. Adrogué HJ, Tasby J, Suki WN. Intracellular pH in the control of the H+ pump: evidence from CO2 studies in the isolated turtle bladder. Trans Assoc Am Physicians. 1982; 95:135-44. PMID: 6304972.
      View in: PubMed
    60. Adrogué HJ, Madias NE. Changes in plasma potassium concentration during acute acid-base disturbances. Am J Med. 1981 Sep; 71(3):456-67. PMID: 7025622.
      View in: PubMed
    61. Adrogué HJ, Frazier MR, Zeluff B, Suki WN. Systemic calciphylaxis revisited. Am J Nephrol. 1981; 1(3-4):177-83. PMID: 7349051.
      View in: PubMed
    62. Madias NE, Adrogué HJ, Cohen JJ. Maladaptive renal response to secondary hypercapnia in chronic metabolic alkalosis. Am J Physiol. 1980 Apr; 238(4):F283-9. PMID: 7377300.
      View in: PubMed
    63. Ayus JC, Olivero JJ, Adrogué HJ. Alkalemia associated with renal failure. Correction by hemodialysis with low-bicarbonate dialysate. Arch Intern Med. 1980 Apr; 140(4):513-5. PMID: 7362382.
      View in: PubMed
    64. Madias NE, Adrogué HJ, Horowitz GL, Cohen JJ, Schwartz WB. A redefinition of normal acid-base equilibrium in man: carbon dioxide tension as a key determinant of normal plasma bicarbonate concentration. Kidney Int. 1979 Nov; 16(5):612-8. PMID: 44886.
      View in: PubMed
    65. Madias NE, Ayus JC, Adrogué HJ. Increased anion gap in metabolic alkalosis: the role of plasma-protein equivalency. N Engl J Med. 1979 Jun 21; 300(25):1421-3. PMID: 35749.
      View in: PubMed
    66. Madias NE, Adrogué HJ, Cohen JJ, Schwartz WB. Effect of natural variations in PaCO2 on plasma [HCO3-] in dogs: a redefinition of normal. Am J Physiol. 1979 Jan; 236(1):F30-5. PMID: 35008.
      View in: PubMed
    67. Adrogué HJ, Brensilver J, Madias NE. Changes in the plasma anion gap during chronic metabolic acid-base disturbances. Am J Physiol. 1978 Oct; 235(4):F291-7. PMID: 29493.
      View in: PubMed
    68. Adrogue HJ, Etcheverry JC. [Renal thromboembolism]. Rev Clin Esp. 1976 Aug 31; 142(4):343-7. PMID: 968122.
      View in: PubMed
    69. Adrogué HJ, Villamil MF, Roehr EE, Etcheverry JC, Roncoroni AJ. Correction of severe metabolic acidosis: a physiological approach. Acta Physiol Lat Am. 1976; 26(6):439-46. PMID: 28634.
      View in: PubMed
    70. Adrogue HJ, Roehr EE, Roncoroni AJ. Contraction alkalosis during recovery of cardio-respiratory failure. Medicina (B Aires). 1974 Mar; 34(2):133-8. PMID: 4851171.
      View in: PubMed
    71. Adrogue HJ, Yeyati N, Obrutsky CW, Rosenberg M, Roncoroni AJ. Potassium disturbances in open heart surgery. Medicina (B Aires). 1971 Jan-Feb; 31(1):13-20. PMID: 5561615.
      View in: PubMed
    72. Adrogué HJ, Etcheverry JC, Taquini AC. Hemodynamic response to hypoxia in dogs with special reference to ventilation. Acta Physiol Lat Am. 1970; 20(1):1-12. PMID: 5486933.
      View in: PubMed
    73. Adrogue HJ, Roncoroni AJ. [Inappropriate secretion of antidiuretic hormone in a patient with severe chronic lung diseases and sequelae of tuberculosis]. Medicina (B Aires). 1969 Mar-Apr; 29(2):119-26. PMID: 5795131.
      View in: PubMed
    74. Taquini CM, Adrogué HJ, Raimondi A, Taquini AC. Cardiovascular and renal adaptation to anoxia. Acta Physiol Lat Am. 1969; 19(1):49-55. PMID: 5800615.
      View in: PubMed
    75. Adrogué HJ, Gennari FJ, Galla JH, Madias NE. 4. Assessing acid-base disorders. . Kidney Int. 2009 Dec;76(12):1239-47. doi: 10.1038/ki.2009.359. Epub 2009 Oct 7. Review. PMID: 19812535.
    76. Adrogué HJ, Madias NE. Shared primacy of sodium and potassium on cardiovascular risk. Am J Kidney Dis. 2009 Oct;54(4):598-601. PMID: 19577349.
    77. Adrogué HJ, Madias NE. Sodium and potassium in the pathogenesis of hypertension. N Engl J Med. 2007 May 10;356(19):1966-78. Review. .
    78. Adrogué HJ, Madias NE. PCO2 and [K+]p in metabolic acidosis: certainty for the first and uncertainty for the other. J Am Soc Nephrol. 2004 Jun;15(6):1667-8. .
    79. Madias NE, Adrogué HJ. Cross-talk between two organs: how the kidney responds to disruption of acid-base balance by the lung. Nephron Physiol. 2003;93(3):p61-6.
    80. Adrogué HJ, Rashad MN, Gorin AB, Yacoub J, Madias NE. Assessing acid-base status in circulatory failure. Differences between arterial and central venous blood. N Engl J Med. 1989 May 18;320(20):1312-6.
    81. Adrogué HJ, Madias NE. Aiding fluid prescription for the dysnatremias. Intensive Care Med. 1997 Mar;23(3):309-16.
    82. Adrogué HJ, Brensilver J, Cohen JJ, Madias NE. Influence of steady-state alterations in acid-base equilibrium on the fate of administered bicarbonate in the dog. J Clin Invest. 1983 Apr;71(4):867-83.
    83. Adrogué HJ, Madias NE. Influence of chronic respiratory acid-base disorders on acute CO2 titration curve. J Appl Physiol (1985). 1985 Apr;58(4):1231-8. .
    84. Madias NE, Cohen JJ, Adrogué HJ. Am J Physiol. 1990 Mar;258(3 Pt 2):F479-85. Influence of acute and chronic respiratory alkalosis on preexisting chronic metabolic alkalosis.
    85. Adrogué HJ, Rashad MN, Gorin AB, Yacoub J, Madias NE. Arteriovenous acid-base disparity in circulatory failure: studies on mechanism. Am J Physiol. 1989 Dec;257(6 Pt 2):F1087-93.
    86. Taquini CM, Adrogué HJ, Raimondi AC, Taquini AC: Cardiovascular and renal adaptation to hypoxia. Acta. Physiol. Latinoam. 19:49-55, 1969.
    87. Adrogue HJ, Madias NE. Secondary responses to altered acid-base status: the rules of engagement. J Am Soc Nephrol. 2010 Jun;21(6):920-3.
    88. Madias NE, Adrogué HJ, Horowitz GL, Cohen JJ, Schwartz WB: . A redefinition of normal acid-base equilibrium in man: Carbon dioxide tension as a key determinant of plasma bicarbonate concentration. Kidney Int. 16:612-618, 1979.
    89. Madias NE, Adrogué HJ, Cohen JJ. Maladaptive renal response to secondary hypercapnia in chronic metabolic alkalosis. Am J Physiol. 1980 Apr;238(4):F283-9.
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