NUMAN OEZGUEN

TitleInstructor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
Address1102 BATES
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Luck B, Horvath TD, Engevik KA, Ruan W, Haidacher SJ, Hoch KM, Oezguen N, Spinler JK, Haag AM, Versalovic J, Engevik MA. Neurotransmitter Profiles Are Altered in the Gut and Brain of Mice Mono-Associated with Bifidobacterium dentium. Biomolecules. 2021 07 23; 11(8). PMID: 34439760.
      Citations:    Fields:    
    2. Gonzales-Luna AJ, Spinler JK, Oezguen N, Khan MAW, Danhof HA, Endres BT, Alam MJ, Begum K, Lancaster C, Costa GP, Savidge TC, Hurdle JG, Britton R, Garey KW. Systems biology evaluation of refractory Clostridioides difficile infection including multiple failures of fecal microbiota transplantation. Anaerobe. 2021 Aug; 70:102387. PMID: 34044101.
      Citations:    Fields:    
    3. Norsigian CJ, Danhof HA, Brand CK, Oezguen N, Midani FS, Palsson BO, Savidge TC, Britton RA, Spinler JK, Monk JM. Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence. NPJ Syst Biol Appl. 2020 10 20; 6(1):31. PMID: 33082337.
      Citations: 1     Fields:    
    4. Spinler JK, Oezguen N, Runge JK, Luna RA, Karri V, Yang J, Hirschi KD. Dietary impact of a plant-derived microRNA on the gut microbiome. ExRNA. 2020; 2. PMID: 33542959.
      Citations: 2     
    5. Horvath TD, Haidacher SJ, Oezguen N, Hoch KM, Auchtung JM, Haag AM. Ruggedness testing of liquid chromatography-tandem mass spectrometry system components using microbiome-relevant methods and matrices. J Microbiol Methods. 2020 10; 177:106020. PMID: 32795635.
      Citations:    Fields:    Translation:HumansCells
    6. Hall AE, Engevik MA, Oezguen N, Haag A, Versalovic J. ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential. Microb Cell Fact. 2019 Dec 12; 18(1):212. PMID: 31830990.
      Citations: 1     Fields:    Translation:Cells
    7. Oezguen N, Yalcinkaya N, Kücükali CI, Dahdouli M, Hollister EB, Luna RA, Türkoglu R, Kürtüncü M, Eraksoy M, Savidge TC, Tüzün E. Microbiota stratification identifies disease-specific alterations in neuro-Behçet's disease and multiple sclerosis. Clin Exp Rheumatol. 2019 Nov-Dec; 37 Suppl 121(6):58-66. PMID: 31172918.
      Citations: 8     Fields:    Translation:Humans
    8. Hollister EB, Oezguen N, Chumpitazi BP, Luna RA, Weidler EM, Rubio-Gonzales M, Dahdouli M, Cope JL, Mistretta TA, Raza S, Metcalf GA, Muzny DM, Gibbs RA, Petrosino JF, Heitkemper M, Savidge TC, Shulman RJ, Versalovic J. Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome. J Mol Diagn. 2019 05; 21(3):449-461. PMID: 31005411.
      Citations: 17     Fields:    Translation:HumansCells
    9. Spinler JK, Auchtung J, Brown A, Boonma P, Oezguen N, Ross CL, Luna RA, Runge J, Versalovic J, Peniche A, Dann SM, Britton RA, Haag A, Savidge TC. Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis. Infect Immun. 2017 10; 85(10). PMID: 28760934.
      Citations: 18     Fields:    Translation:HumansCells
    10. Labus JS, Hollister EB, Jacobs J, Kirbach K, Oezguen N, Gupta A, Acosta J, Luna RA, Aagaard K, Versalovic J, Savidge T, Hsiao E, Tillisch K, Mayer EA. Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome. Microbiome. 2017 05 01; 5(1):49. PMID: 28457228.
      Citations: 64     Fields:    Translation:HumansCells
    11. Luna RA, Oezguen N, Balderas M, Venkatachalam A, Runge JK, Versalovic J, Veenstra-VanderWeele J, Anderson GM, Savidge T, Williams KC. Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder. Cell Mol Gastroenterol Hepatol. 2017 Mar; 3(2):218-230. PMID: 28275689.
      Citations: 51     Fields:    
    12. Chen D, Oezguen N, Urvil P, Ferguson C, Dann SM, Savidge TC. Regulation of protein-ligand binding affinity by hydrogen bond pairing. Sci Adv. 2016 03; 2(3):e1501240. PMID: 27051863.
      Citations: 45     Fields:    Translation:Cells
    13. Joffré E, von Mentzer A, Abd El Ghany M, Oezguen N, Savidge T, Dougan G, Svennerholm AM, Sjöling Å. Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors. J Bacteriol. 2015 Jan; 197(2):392-403. PMID: 25404692.
      Citations: 10     Fields:    
    14. Li S, Shi L, Yang Z, Zhang Y, Perez-Cordon G, Huang T, Ramsey J, Oezguen N, Savidge TC, Feng H. Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis. Infect Immun. 2015 Feb; 83(2):502-13. PMID: 25404023.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    15. Endsley MA, Somasunderam AD, Li G, Oezguen N, Thiviyanathan V, Murray JL, Rubin DH, Hodge TW, O'Brien WA, Lewis B, Ferguson MR. Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain. Virology. 2014 Apr; 454-455:60-6. PMID: 24725932.
      Citations: 8     Fields:    Translation:HumansCells
    16. Chumpitazi BP, Hollister EB, Oezguen N, Tsai CM, McMeans AR, Luna RA, Savidge TC, Versalovic J, Shulman RJ. Gut microbiota influences low fermentable substrate diet efficacy in children with irritable bowel syndrome. Gut Microbes. 2014 Mar-Apr; 5(2):165-75. PMID: 24637601.
      Citations: 33     Fields:    Translation:HumansCells
    17. Hegde ML, Tsutakawa SE, Hegde PM, Holthauzen LM, Li J, Oezguen N, Hilser VJ, Tainer JA, Mitra S. The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol. 2013 Jul 10; 425(13):2359-71. PMID: 23542007.
      Citations: 24     Fields:    Translation:Cells
    18. Apte-Sengupta S, Negi S, Leonard VH, Oezguen N, Navaratnarajah CK, Braun W, Cattaneo R. Base of the measles virus fusion trimer head receives the signal that triggers membrane fusion. J Biol Chem. 2012 Sep 21; 287(39):33026-35. PMID: 22859308.
      Citations: 30     Fields:    Translation:HumansCells
    19. Oezguen N, Power TD, Urvil P, Feng H, Pothoulakis C, Stamler JS, Braun W, Savidge TC. Clostridial toxins: sensing a target in a hostile gut environment. Gut Microbes. 2012 Jan-Feb; 3(1):35-41. PMID: 22356854.
      Citations: 2     Fields:    Translation:HumansCells
    20. Oezguen N, Mantha AK, Izumi T, Schein CH, Mitra S, Braun W. MD simulation and experimental evidence for Mg²+ binding at the B site in human AP endonuclease 1. Bioinformation. 2011; 7(4):184-98. PMID: 22102776.
      Citations: 6     
    21. Bhavnani SK, Victor S, Calhoun WJ, Busse WW, Bleecker E, Castro M, Ju H, Pillai R, Oezguen N, Bellala G, Brasier AR. How cytokines co-occur across asthma patients: from bipartite network analysis to a molecular-based classification. J Biomed Inform. 2011 Dec; 44 Suppl 1:S24-S30. PMID: 21986291.
      Citations: 13     Fields:    Translation:Humans
    22. Oezguen N, Kumar S. Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions. J Drug Metab Toxicol. 2011 Aug 30; 2:1000110. PMID: 25426333.
      Citations: 2     
    23. Savidge TC, Urvil P, Oezguen N, Ali K, Choudhury A, Acharya V, Pinchuk I, Torres AG, English RD, Wiktorowicz JE, Loeffelholz M, Kumar R, Shi L, Nie W, Braun W, Herman B, Hausladen A, Feng H, Stamler JS, Pothoulakis C. Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins. Nat Med. 2011 Aug 21; 17(9):1136-41. PMID: 21857653.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    24. Navaratnarajah CK, Oezguen N, Rupp L, Kay L, Leonard VH, Braun W, Cattaneo R. The heads of the measles virus attachment protein move to transmit the fusion-triggering signal. Nat Struct Mol Biol. 2011 Feb; 18(2):128-34. PMID: 21217701.
      Citations: 66     Fields:    Translation:AnimalsCells
    25. Schein CH, Oezguen N, van der Heden van Noort GJ, Filippov DV, Paul A, Kumar E, Braun W. NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU). Peptides. 2010 Aug; 31(8):1441-8. PMID: 20441784.
      Citations: 11     Fields:    Translation:HumansCells
    26. Kumar S, Qiu H, Oezguen N, Herlyn H, Halpert JR, Wojnowski L. Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. Drug Metab Dispos. 2009 Jun; 37(6):1328-33. PMID: 19299527.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    27. Ivanciuc O, Schein CH, Garcia T, Oezguen N, Negi SS, Braun W. Structural analysis of linear and conformational epitopes of allergens. Regul Toxicol Pharmacol. 2009 Aug; 54(3 Suppl):S11-9. PMID: 19121639.
      Citations: 14     Fields:    Translation:Cells
    28. Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun W. Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes. Mol Immunol. 2008 Aug; 45(14):3740-7. PMID: 18621419.
      Citations: 29     Fields:    Translation:Cells
    29. Leonard VH, Sinn PL, Hodge G, Miest T, Devaux P, Oezguen N, Braun W, McCray PB, McChesney MB, Cattaneo R. Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed. J Clin Invest. 2008 Jul; 118(7):2448-58. PMID: 18568079.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    30. Oezguen N, Kumar S, Hindupur A, Braun W, Muralidhara BK, Halpert JR. Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes. J Biol Chem. 2008 Aug 01; 283(31):21808-16. PMID: 18495666.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    31. Mantha AK, Oezguen N, Bhakat KK, Izumi T, Braun W, Mitra S. Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1. J Mol Biol. 2008 May 23; 379(1):28-37. PMID: 18436236.
      Citations: 14     Fields:    Translation:HumansCells
    32. Navaratnarajah CK, Vongpunsawad S, Oezguen N, Stehle T, Braun W, Hashiguchi T, Maenaka K, Yanagi Y, Cattaneo R. Dynamic interaction of the measles virus hemagglutinin with its receptor signaling lymphocytic activation molecule (SLAM, CD150). J Biol Chem. 2008 Apr 25; 283(17):11763-71. PMID: 18292085.
      Citations: 39     Fields:    Translation:AnimalsCells
    33. Negi SS, Schein CH, Oezguen N, Power TD, Braun W. InterProSurf: a web server for predicting interacting sites on protein surfaces. Bioinformatics. 2007 Dec 15; 23(24):3397-9. PMID: 17933856.
      Citations: 46     Fields:    Translation:Cells
    34. Oezguen N, Schein CH, Peddi SR, Power TD, Izumi T, Braun W. A "moving metal mechanism" for substrate cleavage by the DNA repair endonuclease APE-1. Proteins. 2007 Jul 01; 68(1):313-23. PMID: 17427952.
      Citations: 29     Fields:    Translation:HumansCells
    35. Schein CH, Volk DE, Oezguen N, Paul A. Novel, structure-based mechanism for uridylylation of the genome-linked peptide (VPg) of picornaviruses. Proteins. 2006 Jun 01; 63(4):719-26. PMID: 16498624.
      Citations: 10     Fields:    Translation:Cells
    36. Schein CH, Oezguen N, Volk DE, Garimella R, Paul A, Braun W. NMR structure of the viral peptide linked to the genome (VPg) of poliovirus. Peptides. 2006 Jul; 27(7):1676-84. PMID: 16540201.
      Citations: 21     Fields:    Translation:Cells
    37. von Messling V, Oezguen N, Zheng Q, Vongpunsawad S, Braun W, Cattaneo R. Nearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells. J Virol. 2005 May; 79(9):5857-62. PMID: 15827201.
      Citations: 36     Fields:    Translation:AnimalsCells
    38. Schein CH, Zhou B, Oezguen N, Mathura VS, Braun W. Molego-based definition of the architecture and specificity of metal-binding sites. Proteins. 2005 Jan 01; 58(1):200-10. PMID: 15505785.
      Citations: 19     Fields:    Translation:Cells
    39. Ivanciuc O, Oezguen N, Mathura VS, Schein CH, Xu Y, Braun W. Using property based sequence motifs and 3D modeling to determine structure and functional regions of proteins. Curr Med Chem. 2004 Mar; 11(5):583-93. PMID: 15032606.
      Citations: 18     Fields:    Translation:HumansCells
    40. Izumi T, Schein CH, Oezguen N, Feng Y, Braun W. Effects of backbone contacts 3' to the abasic site on the cleavage and the product binding by human apurinic/apyrimidinic endonuclease (APE1). Biochemistry. 2004 Jan 27; 43(3):684-9. PMID: 14730972.
      Citations: 17     Fields:    Translation:HumansCells
    41. Vongpunsawad S, Oezgun N, Braun W, Cattaneo R. Selectively receptor-blind measles viruses: Identification of residues necessary for SLAM- or CD46-induced fusion and their localization on a new hemagglutinin structural model. J Virol. 2004 Jan; 78(1):302-13. PMID: 14671112.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    42. Schein CH, Ozgün N, Izumi T, Braun W. Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases. BMC Bioinformatics. 2002 Nov 25; 3:37. PMID: 12445335.
      Citations: 10     Fields:    Translation:HumansCells
    43. Murtazina D, Puchkaev AV, Schein CH, Oezguen N, Braun W, Nanavati A, Pikuleva IA. Membrane-protein interactions contribute to efficient 27-hydroxylation of cholesterol by mitochondrial cytochrome P450 27A1. J Biol Chem. 2002 Oct 04; 277(40):37582-9. PMID: 12124390.
      Citations: 16     Fields:    Translation:AnimalsCells
    44. Oezguen N, Adamian L, Xu Y, Rajarathnam K, Braun W. Automated assignment and 3D structure calculations using combinations of 2D homonuclear and 3D heteronuclear NOESY spectra. J Biomol NMR. 2002 Mar; 22(3):249-63. PMID: 11991354.
      Citations: 7     Fields:    Translation:AnimalsCells
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