TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentBreast Center
    DivisionBreast Cancer Center

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bu W, Creighton CJ, Heavener KS, Gutierrez C, Dou Y, Ku AT, Zhang Y, Jiang W, Urrutia J, Jiang W, Yue F, Jia L, Ibrahim AA, Zhang B, Huang S, Li Y. Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Sci Adv. 2023 05 12; 9(19):eade0059. PMID: 37172086; PMCID: PMC10181191.
    2. Bu W, Li Y. In Vivo Gene Delivery into Mouse Mammary Epithelial Cells Through Mammary Intraductal Injection. J Vis Exp. 2023 Feb 10; (192). PMID: 36847377.
      Citations:    Fields:    Translation:AnimalsCells
    3. Ku AT, Young AIJ, Ibrahim AA, Bu W, Jiang W, Lin M, Williams LC, McCue BL, Miles G, Nagi C, Behbod F, Li Y. Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models. Cancer Prev Res (Phila). 2023 02 06; 16(2):65-73. PMID: 36343340; PMCID: PMC9905287.
    4. Meng Y, Chen L, Chen Y, Shi J, Zhang Z, Wang Y, Wu F, Jiang X, Yang W, Zhang L, Wang C, Meng X, Wu Y, Bu W. Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing. Nat Commun. 2022 Nov 29; 13(1):7353. PMID: 36446788.
    5. Wang X, Shi Z, Lu HY, Kim JJ, Bu W, Villalobos JA, Perera DN, Jung SY, Wang T, Grimm SL, Taylor BC, Rajapakshe K, Park H, Wulfkuhle J, Young NL, Li Y, Coarfa C, Edwards DP, Huang S. High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array. J Proteomics. 2022 06 30; 262:104596. PMID: 35489683; PMCID: PMC10165948.
      Citations:    Fields:    Translation:AnimalsCells
    6. Meng X, Yi Y, Meng Y, Lv G, Jiang X, Wu Y, Yang W, Yao Y, Xu H, Bu W. Self-Enhanced Acoustic Impedance Difference Strategy for Detecting the Acidic Tumor Microenvironment. ACS Nano. 2022 03 22; 16(3):4217-4227. PMID: 35254050.
      Citations:    Fields:    
    7. Young A, Bu W, Jiang W, Ku A, Kapali J, Dhamne S, Qin L, Hilsenbeck SG, Du YN, Li Y. Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer. Cancer Prev Res (Phila). 2022 01; 15(1):3-10. PMID: 34667127; PMCID: PMC8741732.
      Citations: 1     Fields:    Translation:HumansAnimals
    8. Zhang H, Lin M, Dong C, Tang Y, An L, Ju J, Wen F, Chen F, Wang M, Wang W, Chen M, Zhao Y, Li J, Hou SX, Lin X, Hu L, Bu W, Wu D, Li L, Jiao S, Zhou Z. An MST4-p?-CateninThr40 Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis. Adv Sci (Weinh). 2021 09; 8(17):e2004850. PMID: 34240584; PMCID: PMC8425901.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    9. Bu W, Li Y. Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo. J Mammary Gland Biol Neoplasia. 2020 12; 25(4):389-396. PMID: 33165800; PMCID: PMC7965254.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    10. Jiang Y, Fu P, Liu Y, Wang C, Zhao P, Chu X, Jiang X, Yang W, Wu Y, Wang Y, Xu G, Hu J, Bu W. Near-infrared light-triggered NO release for spinal cord injury repair. Sci Adv. 2020 09; 6(39). PMID: 32978153; PMCID: PMC7518874.
      Citations: 5     Fields:    Translation:Animals
    11. Song R, Wang H, Zhang M, Liu Y, Meng X, Zhai S, Wang CC, Gong T, Wu Y, Jiang X, Bu W. Near-Infrared Light-Triggered Chlorine Radical (. Cl) Stress for Cancer Therapy. Angew Chem Int Ed Engl. 2020 11 16; 59(47):21032-21040. PMID: 32667130.
      Citations: 6     Fields:    Translation:AnimalsCells
    12. Li L, Li F, Xia Y, Yang X, Lv Q, Fang F, Wang Q, Bu W, Wang Y, Zhang K, Wu Y, Shen J, Jiang M. UVB induces cutaneous squamous cell carcinoma progression by de novo ID4 methylation via methylation regulating enzymes. EBioMedicine. 2020 Jul; 57:102835. PMID: 32574963; PMCID: PMC7317242.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    13. Su W, Wang H, Wang T, Li X, Tang Z, Zhao S, Zhang M, Li D, Jiang X, Gong T, Yang W, Zuo C, Wu Y, Bu W. Auger Electrons Constructed Active Sites on Nanocatalysts for Catalytic Internal Radiotherapy. Adv Sci (Weinh). 2020 May; 7(10):1903585. PMID: 32440481; PMCID: PMC7237849.
      Citations: 2     Fields:    
    14. Meng X, Zhang B, Yi Y, Cheng H, Wang B, Liu Y, Gong T, Yang W, Yao Y, Wang H, Bu W. Accurate and Real-Time Temperature Monitoring during MR Imaging Guided PTT. Nano Lett. 2020 04 08; 20(4):2522-2529. PMID: 32208714.
      Citations: 6     Fields:    Translation:Animals
    15. Gong T, Li Y, Lv B, Wang H, Liu Y, Yang W, Wu Y, Jiang X, Gao H, Zheng X, Bu W. Full-Process Radiosensitization Based on Nanoscale Metal-Organic Frameworks. ACS Nano. 2020 03 24; 14(3):3032-3040. PMID: 32150395.
      Citations: 5     Fields:    
    16. Zhou X, Rao Y, Sun Q, Liu Y, Chen J, Bu W. Long noncoding RNA CPS1-IT1 suppresses melanoma cell metastasis through inhibiting Cyr61 via competitively binding to BRG1. J Cell Physiol. 2019 12; 234(12):22017-22027. PMID: 31111478.
      Citations: 10     Fields:    Translation:Humans
    17. Ma B, Wang S, Liu F, Zhang S, Duan J, Li Z, Kong Y, Sang Y, Liu H, Bu W, Li L. Self-Assembled Copper-Amino Acid Nanoparticles for in Situ Glutathione "AND" H2O2 Sequentially Triggered Chemodynamic Therapy. J Am Chem Soc. 2019 01 16; 141(2):849-857. PMID: 30541274.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    18. Shao C, Shen A, Zhang M, Meng X, Song C, Liu Y, Gao X, Wang P, Bu W. Oxygen Vacancies Enhanced CeO2:Gd Nanoparticles for Sensing a Tumor Vascular Microenvironment by Magnetic Resonance Imaging. ACS Nano. 2018 12 26; 12(12):12629-12637. PMID: 30495921.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    19. Bu W, Liu Z, Jiang W, Nagi C, Huang S, Edwards DP, Jo E, Mo Q, Creighton CJ, Hilsenbeck SG, Leavitt AD, Lewis MT, Wong STC, Li Y. Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes. Cancer Res. 2019 01 01; 79(1):61-71. PMID: 30401712; PMCID: PMC6318055.
      Citations: 14     Fields:    Translation:AnimalsCells
    20. Li M, Bu W, Ren J, Li J, Deng L, Gao M, Gao X, Wang P. Enhanced Synergism of Thermo-chemotherapy For Liver Cancer with Magnetothermally Responsive Nanocarriers. Theranostics. 2018; 8(3):693-709. PMID: 29344299; PMCID: PMC5771086.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    21. Xu Y, Lee DK, Feng Z, Xu Y, Bu W, Li Y, Liao L, Xu J. Breast tumor cell-specific knockout of Twist1 inhibits cancer cell plasticity, dissemination, and lung metastasis in mice. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11494-11499. PMID: 29073077; PMCID: PMC5664488.
      Citations: 50     Fields:    Translation:Animals
    22. Qiao H, Cui Z, Yang S, Ji D, Wang Y, Yang Y, Han X, Fan Q, Qin A, Wang T, He XP, Bu W, Tang T. Targeting Osteocytes to Attenuate Early Breast Cancer Bone Metastasis by Theranostic Upconversion Nanoparticles with Responsive Plumbagin Release. ACS Nano. 2017 07 25; 11(7):7259-7273. PMID: 28692257.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    23. Holloway KR, Sinha VC, Bu W, Toneff M, Dong J, Peng Y, Li Y. Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype. Int J Biol Sci. 2016; 12(4):381-8. PMID: 27019623; PMCID: PMC4807158.
      Citations: 8     Fields:    Translation:Animals
    24. Zhang C, Bu W, Ni D, Zhang S, Li Q, Yao Z, Zhang J, Yao H, Wang Z, Shi J. Synthesis of Iron Nanometallic Glasses and Their Application in Cancer Therapy by a Localized Fenton Reaction. Angew Chem Int Ed Engl. 2016 Feb 05; 55(6):2101-6. PMID: 26836344.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    25. Fan W, Bu W, Zhang Z, Shen B, Zhang H, He Q, Ni D, Cui Z, Zhao K, Bu J, Du J, Liu J, Shi J. X-ray Radiation-Controlled NO-Release for On-Demand Depth-Independent Hypoxic Radiosensitization. Angew Chem Int Ed Engl. 2015 Nov 16; 54(47):14026-30. PMID: 26228648.
      Citations: 32     Fields:    
    26. Zheng ZY, Tian L, Bu W, Fan C, Gao X, Wang H, Liao YH, Li Y, Lewis MT, Edwards D, Zwaka TP, Hilsenbeck SG, Medina D, Perou CM, Creighton CJ, Zhang XH, Chang EC. Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation. Cell Rep. 2015 Jul 21; 12(3):511-24. PMID: 26166574; PMCID: PMC4512851.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    27. Holloway KR, Sinha VC, Toneff MJ, Bu W, Hilsenbeck SG, Li Y. Krt6a-positive mammary epithelial progenitors are not at increased vulnerability to tumorigenesis initiated by ErbB2. PLoS One. 2015; 10(1):e0117239. PMID: 25635772; PMCID: PMC4311910.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    28. Wei W, Tweardy DJ, Tweardy DJ, Zhang M, Zhang X, Landua J, Petrovic I, Bu W, Roarty K, Hilsenbeck SG, Rosen JM, Lewis MT. STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells. 2014 Oct; 32(10):2571-82. PMID: 24891218.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    29. Vadakkan TJ, Landua JD, Bu W, Wei W, Li F, Wong ST, Dickinson ME, Rosen JM, Lewis MT, Zhang M. Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem Cells Transl Med. 2014 Jul; 3(7):857-66. PMID: 24797826; PMCID: PMC4073819.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    30. Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ, Zheng P, Vasudevan S, An L, Yang J, Zhao YJ, Zhang H, Li XN, Rao PH, Leung E, Lu YJ, Gray JW, Schiff R, Hilsenbeck SG, Osborne CK, Yang J, Zhang H. Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells. J Pathol. 2014 Jan; 232(1):75-86. PMID: 24122835; PMCID: PMC3966110.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    31. Cheng L, Liu J, Gu X, Gong H, Shi X, Liu T, Wang C, Wang X, Liu G, Xing H, Bu W, Sun B, Liu Z. PEGylated WS(2) nanosheets as a multifunctional theranostic agent for in vivo dual-modal CT/photoacoustic imaging guided photothermal therapy. Adv Mater. 2014 Mar 26; 26(12):1886-93. PMID: 24375758.
      Citations: 143     Fields:    Translation:HumansAnimalsCells
    32. Bu W, Zhang X, Dai H, Huang S, Li Y. Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis. PLoS One. 2013; 8(11):e78720. PMID: 24265712; PMCID: PMC3827100.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    33. Xia Y, Yang W, Bu W, Ji H, Zhao X, Zheng Y, Lin X, Li Y, Lu Z. Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells. J Biol Chem. 2013 Jul 05; 288(27):19321-9. PMID: 23678002; PMCID: PMC3707636.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    34. Chen Y, Xu P, Chen H, Li Y, Bu W, Shu Z, Li Y, Zhang J, Zhang L, Pan L, Cui X, Hua Z, Wang J, Zhang L, Shi J. Colloidal HPMO nanoparticles: silica-etching chemistry tailoring, topological transformation, and nano-biomedical applications. Adv Mater. 2013 Jun 11; 25(22):3100-5. PMID: 23418108.
      Citations: 12     Fields:    Translation:HumansCells
    35. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-induced and PKCe monoubiquitylation-dependent NF-?B activation upregulates PKM2 expression and promotes tumorigenesis. Mol Cell. 2012 Dec 14; 48(5):771-84. PMID: 23123196; PMCID: PMC3526114.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    36. Li M, Tian Y, Zhao Y, Bu W. Higher level phylogeny and the first divergence time estimation of Heteroptera (Insecta: Hemiptera) based on multiple genes. PLoS One. 2012; 7(2):e32152. PMID: 22384163; PMCID: PMC3288068.
      Citations: 23     Fields:    Translation:Animals
    37. Reddy JP, Peddibhotla S, Bu W, Zhao J, Haricharan S, Du YC, Podsypanina K, Rosen JM, Donehower LA, Li Y. Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3728-33. PMID: 20133707; PMCID: PMC2840493.
      Citations: 33     Fields:    Translation:Animals
    38. Bu W, Xin L, Toneff M, Li L, Li Y. Lentivirus vectors for stably introducing genes into mammary epithelial cells in vivo. J Mammary Gland Biol Neoplasia. 2009 Dec; 14(4):401-4. PMID: 19936990.
      Citations: 20     Fields:    Translation:AnimalsCells
    39. Siwko SK, Bu W, Gutierrez C, Lewis B, Jechlinger M, Schaffhausen B, Li Y. Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors. Neoplasia. 2008 Jul; 10(7):653-62, 1 p following 662. PMID: 18592025; PMCID: PMC2435599.
      Citations: 21     Fields:    Translation:AnimalsCells
    40. Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM. Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006; 8(3):R29. PMID: 16790075; PMCID: PMC1557733.
      Citations: 21     Fields:    Translation:AnimalsCells
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