JAMES CROWE

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Radiology
Address6621 FANNIN
Houston, TX 77030
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    R29HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2002
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    R01HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2003
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    R21DE014039     (CROWE, JAMES E)Sep 1, 2000 - Aug 31, 2003
    NIH/NIDCR
    RESPIRATORY VIRUS NEUTRALIZATION BY INTRACELLULAR AB
    Role: Principal Investigator

    U01AI048512     (CROWE, JAMES E)Sep 15, 2000 - Aug 31, 2003
    NIH/NIAID
    HUMAN MONOCLONAL ANTIBODIES THAT NEUTRALIZE VACCINIA
    Role: Principal Investigator

    R03TW001497     (CROWE, JAMES E)Aug 15, 2002 - Jun 30, 2005
    NIH/FIC
    Epitope Specificity of RSV Nucleoprotein-Specific T Cel*
    Role: Principal Investigator

    R01AI048677     (CROWE, JAMES E)Sep 1, 2002 - Aug 31, 2006
    NIH/NIAID
    Novel methods for generation of human B cell hybridomas
    Role: Principal Investigator

    R01AI053222     (CROWE, JAMES E)Jul 1, 2003 - Jun 30, 2007
    NIH/NIAID
    Human T Cells Responses to RSV
    Role: Principal Investigator

    R01AI057661     (CROWE, JAMES E)Sep 15, 2003 - Feb 28, 2008
    NIH/NIAID
    Cell-Mediated Immune Responses to Vaccinia Viruses
    Role: Principal Investigator

    S10RR019032     (CROWE, JAMES E)Apr 1, 2004 - Mar 31, 2005
    NIH/NCRR
    High Throughput Flow Cytometry Sorter
    Role: Principal Investigator

    R01AI059597     (CROWE, JAMES E)Apr 1, 2004 - Feb 28, 2010
    NIH/NIAID
    Alphavirus-based Vaccine for Prevention of MPV Infection
    Role: Principal Investigator

    R01AI057933     (CROWE, JAMES E)Jun 15, 2004 - May 31, 2009
    NIH/NIAID
    Human Antibody Responses to Rotavirus
    Role: Principal Investigator

    PN1EY016567     (CROWE, JAMES E)Sep 30, 2004 - Jul 31, 2005
    NIH/NEI
    Immunomodulation on the Nanoscale (RMI)
    Role: Principal Investigator

    R21AG030321     (CROWE, JAMES E)Sep 30, 2007 - Jul 31, 2010
    NIH/NIA
    Respiratory Syncytial Virus Nanoparticle Vaccines
    Role: Principal Investigator

    U01AI078407     (CROWE, JAMES E)Mar 15, 2008 - Feb 28, 2013
    NIH/NIAID
    Clonal Analysis of the Human B Cell Response to HIV
    Role: Principal Investigator

    R21AI083574     (CROWE, JAMES E)Jul 22, 2009 - Jun 30, 2011
    NIH/NIAID
    Rotavirus VP6 Specific Human IgA Antibodies
    Role: Principal Investigator

    S10RR027977     (CROWE, JAMES E)Mar 4, 2010 - Mar 3, 2011
    NIH/NCRR
    Multi-Laser Flow Cytometer for Polychromatic Analysis
    Role: Principal Investigator

    T32AI089554     (CROWE, JAMES E)May 1, 2010 - Apr 30, 2015
    NIH/NIAID
    Virology Training Program
    Role: Principal Investigator

    R01AI106002     (CROWE, JAMES E)Aug 15, 2012 - Jul 31, 2016
    NIH/NIAID
    Molecular Determinants of Cross-Reactive Antibody Response to Influenza in Humans
    Role: Principal Investigator

    R21AI103834     (CROWE, JAMES E)Jun 1, 2013 - May 31, 2015
    NIH/NIAID
    Human neutralizing monoclonal antibodies for Rift Valley fever virus
    Role: Principal Investigator

    R56AI110750     (MEILER, JENS)Sep 5, 2014 - Aug 31, 2015
    NIH/NIAID
    Hybrid Methods for Prediction and Design of Novel Human Influenza Antibodies
    Role: Co-Principal Investigator

    R01AI114816     (CROWE, JAMES E)Feb 10, 2015 - Jan 31, 2020
    NIH/NIAID
    Structural and functional basis of ultra potent CHKV neutralization by human mAbs
    Role: Principal Investigator

    U19AI117905     (CROWE, JAMES E)May 1, 2015 - Apr 30, 2020
    NIH/NIAID
    Structure based design of antibodies and vaccines
    Role: Principal Investigator

    R01AI127828     (CROWE, JAMES E)Jan 1, 2017 - Dec 31, 2021
    NIH/NIAID
    Human neutralizing antibodies for Zika virus
    Role: Principal Investigator

    R01AI141661     (BUKREYEV, ALEXANDER)Nov 1, 2018 - Oct 31, 2023
    NIH/NIAID
    Epitope-Based Design and Modified RNA Platform for Bivalent Marburgvirus Vaccine
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine. Nat Commun. 2022 Jun 16; 13(1):3466. PMID: 35710908.
      Citations:    Fields:    
    2. Bozhanova NG, Flyak AI, Brown BP, Ruiz SE, Salas J, Rho S, Bombardi RG, Myers L, Soto C, Bailey JR, Crowe JE, Bjorkman PJ, Meiler J. Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals. Nat Commun. 2022 Jun 08; 13(1):3178. PMID: 35676279.
      Citations:    Fields:    Translation:HumansCells
    3. Suryadevara N, Shiakolas AR, VanBlargan LA, Binshtein E, Chen RE, Case JB, Kramer KJ, Armstrong EC, Myers L, Trivette A, Gainza C, Nargi RS, Selverian CN, Davidson E, Doranz BJ, Diaz SM, Handal LS, Carnahan RH, Diamond MS, Georgiev IS, Crowe JE. An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer. J Clin Invest. 2022 Jun 01; 132(11). PMID: 35472136.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Vogt MR, Wright PF, Hickey WF, De Buysscher T, Boyd KL, Crowe JE. Enterovirus D68 in the Anterior Horn Cells of a Child with Acute Flaccid Myelitis. N Engl J Med. 2022 05 26; 386(21):2059-2060. PMID: 35613028.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    5. Pfaff-Kilgore JM, Davidson E, Kadash-Edmondson K, Hernandez M, Rosenberg E, Chambers R, Castelli M, Clementi N, Mancini N, Bailey JR, Crowe JE, Law M, Doranz BJ. Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening. Cell Rep. 2022 May 24; 39(8):110859. PMID: 35613596.
      Citations:    Fields:    Translation:HumansCells
    6. Frumento N, Figueroa A, Wang T, Zahid MN, Wang S, Massaccesi G, Stavrakis G, Crowe JE, Flyak AI, Ji H, Ray SC, Shaw G, Cox AL, Bailey JR. Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency. J Clin Invest. 2022 May 19. PMID: 35588376.
      Citations:    Fields:    
    7. Schoeder CT, Gilchuk P, Sangha AK, Ledwitch KV, Malherbe DC, Zhang X, Binshtein E, Williamson LE, Martina CE, Dong J, Armstrong E, Sutton R, Nargi R, Rodriguez J, Kuzmina N, Fiala B, King NP, Bukreyev A, Crowe JE, Meiler J. Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region. PLoS Pathog. 2022 05; 18(5):e1010518. PMID: 35584193.
      Citations:    Fields:    Translation:AnimalsCells
    8. Fowler BD, Kose N, Reidy JX, Handal LS, Skaar EP, Crowe JE. Human Monoclonal Antibodies to Escherichia coli Outer Membrane Protein A Porin Domain Cause Aggregation but Do Not Alter In Vivo Bacterial Burdens in a Murine Sepsis Model. Infect Immun. 2022 Jun 16; 90(6):e0017622. PMID: 35583347.
      Citations:    Fields:    
    9. Bangaru S, Antanasijevic A, Kose N, Sewall LM, Jackson AM, Suryadevara N, Zhan X, Torres JL, Copps J, de la Peña AT, Crowe JE, Ward AB. Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv. 2022 05 06; 8(18):eabn2911. PMID: 35507649.
      Citations:    Fields:    Translation:HumansCells
    10. August A, Attarwala HZ, Himansu S, Kalidindi S, Lu S, Pajon R, Han S, Lecerf JM, Tomassini JE, Hard M, Ptaszek LM, Crowe JE, Zaks T. Author Correction: A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus. Nat Med. 2022 May; 28(5):1095-1096. PMID: 35449420.
      Citations:    Fields:    
    11. Suryadevara N, Gilchuk P, Zost SJ, Mittal N, Zhao LL, Crowe JE, Carnahan RH. Real-time cell analysis: A high-throughput approach for testing SARS-CoV-2 antibody neutralization and escape. STAR Protoc. 2022 Jun 17; 3(2):101387. PMID: 35578733.
      Citations:    Fields:    Translation:HumansCells
    12. Doyle MP, Genualdi JR, Bailey AL, Kose N, Gainza C, Rodriguez J, Reeder KM, Nelson CA, Jethva PN, Sutton RE, Bombardi RG, Gross ML, Julander JG, Fremont DH, Diamond MS, Crowe JE. Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus. mBio. 2022 Apr 14; e0051222. PMID: 35420472.
      Citations:    Fields:    
    13. Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS. Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J Exp Med. 2022 04 04; 219(4). PMID: 35297953.
      Citations:    Fields:    Translation:AnimalsCells
    14. Hu L, Salmen W, Chen R, Zhou Y, Neill F, Crowe JE, Atmar RL, Estes MK, Prasad BVV. Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity. Nat Commun. 2022 03 10; 13(1):1241. PMID: 35273142.
      Citations: 1     Fields:    Translation:HumansCells
    15. Loo YM, McTamney PM, Arends RH, Abram ME, Aksyuk AA, Diallo S, Flores DJ, Kelly EJ, Ren K, Roque R, Rosenthal K, Streicher K, Tuffy KM, Bond NJ, Cornwell O, Bouquet J, Cheng LI, Dunyak J, Huang Y, Rosenbaum AI, Pilla Reddy V, Andersen H, Carnahan RH, Crowe JE, Kuehne AI, Herbert AS, Dye JM, Bright H, Kallewaard NL, Pangalos MN, Esser MT. The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans. Sci Transl Med. 2022 03 09; 14(635):eabl8124. PMID: 35076282.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    16. Shiakolas AR, Kramer KJ, Johnson NV, Wall SC, Suryadevara N, Wrapp D, Periasamy S, Pilewski KA, Raju N, Nargi R, Sutton RE, Walker LM, Setliff I, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking. Nat Biotechnol. 2022 Mar 03. PMID: 35241839.
      Citations: 2     Fields:    
    17. Crowe JE. Bispecific antiviral neutralizing antibodies are twice as nice. Nat Immunol. 2022 03; 23(3):346-347. PMID: 35228693.
      Citations:    Fields:    Translation:HumansCells
    18. Crowe JE, Carnahan RH. Even old foes can learn sweet new tricks. Cell Host Microbe. 2022 02 09; 30(2):151-153. PMID: 35143767.
      Citations:    Fields:    Translation:HumansCells
    19. Cobb RR, Nkolola J, Gilchuk P, Chandrashekar A, Yu J, House RV, Earnhart CG, Dorsey NM, Hopkins SA, Snow DM, Chen RE, VanBlargan LA, Hechenblaickner M, Hoppe B, Collins L, Tomic MT, Nonet GH, Hackett K, Slaughter JC, Lewis MG, Andersen H, Cook A, Diamond MS, Carnahan RH, Barouch DH, Crowe JE. A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques. Med (N Y). 2022 Mar 11; 3(3):188-203.e4. PMID: 35132398.
      Citations: 1     Translation:HumansAnimalsCells
    20. Crowe JE. Human Antibodies for Viral Infections. Annu Rev Immunol. 2022 04 26; 40:349-386. PMID: 35113730.
      Citations:    Fields:    Translation:HumansAnimals
    21. VanBlargan LA, Errico JM, Halfmann PJ, Zost SJ, Crowe JE, Purcell LA, Kawaoka Y, Corti D, Fremont DH, Diamond MS. An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies. Nat Med. 2022 03; 28(3):490-495. PMID: 35046573.
      Citations: 54     Fields:    Translation:HumansCells
    22. Murin CD, Gilchuk P, Crowe JE, Ward AB. Structural Biology Illuminates Molecular Determinants of Broad Ebolavirus Neutralization by Human Antibodies for Pan-Ebolavirus Therapeutic Development. Front Immunol. 2021; 12:808047. PMID: 35082794.
      Citations:    Fields:    Translation:HumansCells
    23. Ogega CO, Skinner NE, Flyak AI, Clark KE, Board NL, Bjorkman PJ, Crowe JE, Cox AL, Ray SC, Bailey JR. B cell overexpression of FCRL5 and PD-1 is associated with low antibody titers in HCV infection. PLoS Pathog. 2022 01; 18(1):e1010179. PMID: 34990486.
      Citations:    Fields:    Translation:HumansCells
    24. Schmitz S, Schmitz EA, Crowe JE, Meiler J. The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta. MAbs. 2022 Jan-Dec; 14(1):2068212. PMID: 35544469.
      Citations:    Fields:    Translation:HumansAnimalsCells
    25. Yuan TZ, Garg P, Wang L, Willis JR, Kwan E, Hernandez AGL, Tuscano E, Sever EN, Keane E, Soto C, Mucker EM, Fouch ME, Davidson E, Doranz BJ, Kailasan S, Aman MJ, Li H, Hooper JW, Saphire EO, Crowe JE, Liu Q, Axelrod F, Sato AK. Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022 Jan-Dec; 14(1):2002236. PMID: 34967699.
      Citations: 1     Fields:    Translation:AnimalsCells
    26. August A, Attarwala HZ, Himansu S, Kalidindi S, Lu S, Pajon R, Han S, Lecerf JM, Tomassini JE, Hard M, Ptaszek LM, Crowe JE, Zaks T. A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus. Nat Med. 2021 12; 27(12):2224-2233. PMID: 34887572.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    27. Gilchuk P, Thomsen I, Yoder S, Brady E, Chappell JD, Stevens LJ, Denison MR, Sutton RE, Chen RE, VanBlargan LA, Suryadevara N, Zost SJ, Schmitz J, Pulley JM, Diamond MS, Rhoads JP, Bernard GR, Self WH, Rice TW, Wheeler AP, Crowe JE, Carnahan RH. Standardized two-step testing of antibody activity in COVID-19 convalescent plasma. iScience. 2022 Jan 21; 25(1):103602. PMID: 34901783.
      Citations: 2     
    28. Gilchuk P, Murin CD, Cross RW, Ilinykh PA, Huang K, Kuzmina N, Borisevich V, Agans KN, Geisbert JB, Zost SJ, Nargi RS, Sutton RE, Suryadevara N, Bombardi RG, Carnahan RH, Bukreyev A, Geisbert TW, Ward AB, Crowe JE. Pan-ebolavirus protective therapy by two multifunctional human antibodies. Cell. 2021 10 28; 184(22):5593-5607.e18. PMID: 34715022.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    29. Alvarado G, Salmen W, Ettayebi K, Hu L, Sankaran B, Estes MK, Venkataram Prasad BV, Crowe JE. Author Correction: Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses. Nat Commun. 2021 Oct 14; 12(1):6090. PMID: 34650069.
      Citations:    Fields:    
    30. Wessel AW, Doyle MP, Engdahl TB, Rodriguez J, Crowe JE, Diamond MS. Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection. mBio. 2021 10 26; 12(5):e0244021. PMID: 34634945.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    31. Gilchuk IM, Bangaru S, Kose N, Bombardi RG, Trivette A, Li S, Turner HL, Carnahan RH, Ward AB, Crowe JE. Human antibody recognition of H7N9 influenza virus HA following natural infection. JCI Insight. 2021 10 08; 6(19). PMID: 34437301.
      Citations: 1     Fields:    Translation:HumansCells
    32. Dong J, Zost SJ, Greaney AJ, Starr TN, Dingens AS, Chen EC, Chen RE, Case JB, Sutton RE, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi RS, Binshtein E, Xie X, Zhang X, Shi PY, Logue J, Weston S, McGrath ME, Frieman MB, Brady T, Tuffy KM, Bright H, Loo YM, McTamney PM, Esser MT, Carnahan RH, Diamond MS, Bloom JD, Crowe JE. Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail. Nat Microbiol. 2021 10; 6(10):1233-1244. PMID: 34548634.
      Citations: 37     Fields:    Translation:HumansCells
    33. Kramer KJ, Johnson NV, Shiakolas AR, Suryadevara N, Periasamy S, Raju N, Williams JK, Wrapp D, Zost SJ, Walker LM, Wall SC, Holt CM, Hsieh CL, Sutton RE, Paulo A, Nargi RS, Davidson E, Doranz BJ, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition. Cell Rep. 2021 10 05; 37(1):109784. PMID: 34592170.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    34. Drury SL, Miller AR, Laut CL, Walter AB, Bennett MR, Su M, Bai M, Jing B, Joseph SB, Metzger EJ, Bane CE, Black CC, Macdonald MT, Dutter BF, Romaine IM, Waterson AG, Sulikowski GA, Jansen ED, Crowe JE, Sciotti RJ, Skaar EP. Simultaneous Exposure to Intracellular and Extracellular Photosensitizers for the Treatment of Staphylococcus aureus Infections. Antimicrob Agents Chemother. 2021 11 17; 65(12):e0091921. PMID: 34516248.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    35. Doyle MP, Kose N, Borisevich V, Binshtein E, Amaya M, Nagel M, Annand EJ, Armstrong E, Bombardi R, Dong J, Schey KL, Broder CC, Zeitlin L, Kuang EA, Bornholdt ZA, West BR, Geisbert TW, Cross RW, Crowe JE. Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein. Cell Rep. 2021 08 31; 36(9):109628. PMID: 34469726.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    36. VanBlargan LA, Adams LJ, Liu Z, Chen RE, Gilchuk P, Raju S, Smith BK, Zhao H, Case JB, Winkler ES, Whitener BM, Droit L, Aziati ID, Bricker TL, Joshi A, Shi PY, Creanga A, Pegu A, Handley SA, Wang D, Boon ACM, Crowe JE, Whelan SPJ, Fremont DH, Diamond MS. A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope. Immunity. 2021 10 12; 54(10):2399-2416.e6. PMID: 34481543.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    37. Williamson LE, Reeder KM, Bailey K, Tran MH, Roy V, Fouch ME, Kose N, Trivette A, Nargi RS, Winkler ES, Kim AS, Gainza C, Rodriguez J, Armstrong E, Sutton RE, Reidy J, Carnahan RH, McDonald WH, Schoeder CT, Klimstra WB, Davidson E, Doranz BJ, Alter G, Meiler J, Schey KL, Julander JG, Diamond MS, Crowe JE. Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress. Cell. 2021 08 19; 184(17):4430-4446.e22. PMID: 34416147.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    38. Kim AS, Kafai NM, Winkler ES, Gilliland TC, Cottle EL, Earnest JT, Jethva PN, Kaplonek P, Shah AP, Fong RH, Davidson E, Malonis RJ, Quiroz JA, Williamson LE, Vang L, Mack M, Crowe JE, Doranz BJ, Lai JR, Alter G, Gross ML, Klimstra WB, Fremont DH, Diamond MS. Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope. Cell. 2021 08 19; 184(17):4414-4429.e19. PMID: 34416146.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    39. Chen EC, Gilchuk P, Zost SJ, Suryadevara N, Winkler ES, Cabel CR, Binshtein E, Chen RE, Sutton RE, Rodriguez J, Day S, Myers L, Trivette A, Williams JK, Davidson E, Li S, Doranz BJ, Campos SK, Carnahan RH, Thorne CA, Diamond MS, Crowe JE. Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals. Cell Rep. 2021 08 24; 36(8):109604. PMID: 34411541.
      Citations: 13     Fields:    
    40. Zost SJ, Dong J, Gilchuk IM, Gilchuk P, Thornburg NJ, Bangaru S, Kose N, Finn JA, Bombardi R, Soto C, Chen EC, Nargi RS, Sutton RE, Irving RP, Suryadevara N, Westover JB, Carnahan RH, Turner HL, Li S, Ward AB, Crowe JE. Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface. J Clin Invest. 2021 08 02; 131(15). PMID: 34156974.
      Citations: 4     Fields:    Translation:HumansCells
    41. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker L, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine. bioRxiv. 2021 Jul 28. PMID: 34341788.
      Citations:    
    42. Engdahl TB, Kuzmina NA, Ronk AJ, Mire CE, Hyde MA, Kose N, Josleyn MD, Sutton RE, Mehta A, Wolters RM, Lloyd NM, Valdivieso FR, Ksiazek TG, Hooper JW, Bukreyev A, Crowe JE. Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection. Cell Rep. 2021 Jul 20; 36(3):109453. PMID: 34289361.
      Citations:    Fields:    
    43. Gilchuk P, Guthals A, Bonissone SR, Shaw JB, Ilinykh PA, Huang K, Bombardi RG, Liang J, Grinyo A, Davidson E, Chen EC, Gunn BM, Alter G, Saphire EO, Doranz BJ, Bukreyev A, Zeitlin L, Castellana N, Crowe JE. Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma. Front Immunol. 2021; 12:706757. PMID: 34335620.
      Citations:    Fields:    Translation:HumansCells
    44. Meyer M, Gunn BM, Malherbe DC, Gangavarapu K, Yoshida A, Pietzsch C, Kuzmina NA, Saphire EO, Collins PL, Crowe JE, Zhu JJ, Suchard MA, Brining DL, Mire CE, Cross RW, Geisbert JB, Samal SK, Andersen KG, Alter G, Geisbert TW, Bukreyev A. Ebola vaccine-induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects. Sci Transl Med. 2021 07 14; 13(602). PMID: 34261800.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    45. Alvarado G, Salmen W, Ettayebi K, Hu L, Sankaran B, Estes MK, Venkataram Prasad BV, Crowe JE. Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses. Nat Commun. 2021 07 14; 12(1):4320. PMID: 34262046.
      Citations: 5     Fields:    Translation:HumansCells
    46. Kodali P, Schoeder CT, Schmitz S, Crowe JE, Meiler J. RosettaCM for antibodies with very long HCDR3s and low template availability. Proteins. 2021 11; 89(11):1458-1472. PMID: 34176159.
      Citations: 1     Fields:    Translation:HumansCells
    47. Shiakolas AR, Johnson N, Kramer KJ, Suryadevara N, Wrapp D, Periasamy S, Pilewski KA, Raju N, Nargi R, Sutton RE, Walker L, Setliff I, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, Georgiev IS. Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking. bioRxiv. 2021 Jun 30. PMID: 34100018.
      Citations:    
    48. Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Liu Z, Jo H, Lee N, Tenneti K, Eschbach JE, Shema Mugisha C, Cousins EM, Cloer EW, Vuong HR, VanBlargan LA, Bailey AL, Gilchuk P, Crowe JE, Diamond MS, Hayes DN, Whelan SPJ, Horani A, Brody SL, Goldfarb D, Major MB, Kutluay SB. Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Rep. 2021 07 13; 36(2):109364. PMID: 34214467.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    49. Chen RE, Winkler ES, Case JB, Aziati ID, Bricker TL, Joshi A, Darling TL, Ying B, Errico JM, Shrihari S, VanBlargan LA, Xie X, Gilchuk P, Zost SJ, Droit L, Liu Z, Stumpf S, Wang D, Handley SA, Stine WB, Shi PY, Davis-Gardner ME, Suthar MS, Knight MG, Andino R, Chiu CY, Ellebedy AH, Fremont DH, Whelan SPJ, Crowe JE, Purcell L, Corti D, Boon ACM, Diamond MS. In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. Nature. 2021 08; 596(7870):103-108. PMID: 34153975.
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    50. Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, Suryadevara N, Chen RE, Martinez DR, Nargi RS, Sutton RE, Ledgerwood JE, Graham BS, Diamond MS, Haynes BF, Acharya P, Carnahan RH, Crowe JE, Baric RS, Morris L, McLellan JS, Georgiev IS. Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions. Cell Rep Med. 2021 06 15; 2(6):100313. PMID: 34056628.
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    51. Engdahl TB, Kuzmina NA, Ronk AJ, Mire CE, Hyde MA, Kose N, Josleyn MD, Sutton RE, Mehta A, Wolters RM, Lloyd NM, Valdivieso FR, Ksiazek TG, Hooper JW, Bukreyev A, Crowe JE. Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection. Cell Rep. 2021 05 04; 35(5):109086. PMID: 33951434.
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    52. Chen EC, Gilchuk P, Zost SJ, Suryadevara N, Winkler ES, Cabel CR, Binshtein E, Sutton RE, Rodriguez J, Day S, Myers L, Trivette A, Williams JK, Davidson E, Li S, Doranz BJ, Campos SK, Carnahan RH, Thorne CA, Diamond MS, Crowe JE. Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals. bioRxiv. 2021 May 03. PMID: 33972937.
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    53. VanBlargan L, Adams L, Liu Z, Chen RE, Gilchuk P, Raju S, Smith B, Zhao H, Case JB, Winkler ES, Whitener B, Droit L, Aziati I, Shi PY, Creanga A, Pegu A, Handley S, Wang D, Boon A, Crowe JE, Whelan SPJ, Fremont D, Diamond M. A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope. bioRxiv. 2021 Apr 26. PMID: 33907753.
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    54. Diamond M, Chen R, Winkler E, Case J, Aziati I, Bricker T, Joshi A, Darling T, Ying B, Errico J, Shrihari S, VanBlargan L, Xie X, Gilchuk P, Zost S, Droit L, Liu Z, Stumpf S, Wang D, Handley S, Stine W, Shi PY, Garcia-Knight M, Andino R, Chiu C, Ellebedy A, Fremont D, Whelan S, Crowe J, Purcell L, Corti D, Boon A. In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. Res Sq. 2021 Apr 23. PMID: 34013259.
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    56. Chapman NS, Zhao H, Kose N, Westover JB, Kalveram B, Bombardi R, Rodriguez J, Sutton R, Genualdi J, LaBeaud AD, Mutuku FM, Pittman PR, Freiberg AN, Gowen BB, Fremont DH, Crowe JE. Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition. Proc Natl Acad Sci U S A. 2021 04 06; 118(14). PMID: 33782133.
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    57. Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Chen RE, Shi PY, Carnahan RH, Thackray LB, Diamond MS, Crowe JE. Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein. Cell. 2021 04 29; 184(9):2316-2331.e15. PMID: 33773105.
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    58. Schoeder CT, Schmitz S, Adolf-Bryfogle J, Sevy AM, Finn JA, Sauer MF, Bozhanova NG, Mueller BK, Sangha AK, Bonet J, Sheehan JH, Kuenze G, Marlow B, Smith ST, Woods H, Bender BJ, Martina CE, Del Alamo D, Kodali P, Gulsevin A, Schief WR, Correia BE, Crowe JE, Meiler J, Moretti R. Modeling Immunity with Rosetta: Methods for Antibody and Antigen Design. Biochemistry. 2021 03 23; 60(11):825-846. PMID: 33705117.
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    60. Dong J, Zost S, Greaney A, Starr TN, Dingens AS, Chen EC, Chen R, Case B, Sutton R, Gilchuk P, Rodriguez J, Armstrong E, Gainza C, Nargi R, Binshtein E, Xie X, Zhang X, Shi PY, Logue J, Weston S, McGrath M, Frieman M, Brady T, Tuffy K, Bright H, Loo YM, McvTamney P, Esser M, Carnahan R, Diamond M, Bloom J, Crowe JE. Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail. bioRxiv. 2021 Mar 01. PMID: 33532768.
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    61. Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe JE, Lok SM. Antibody affinity versus dengue morphology influences neutralization. PLoS Pathog. 2021 02; 17(2):e1009331. PMID: 33621239.
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    62. Winkler ES, Gilchuk P, Yu J, Bailey AL, Chen RE, Chong Z, Zost SJ, Jang H, Huang Y, Allen JD, Case JB, Sutton RE, Carnahan RH, Darling TL, Boon ACM, Mack M, Head RD, Ross TM, Crowe JE, Diamond MS. Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection. Cell. 2021 04 01; 184(7):1804-1820.e16. PMID: 33691139.
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    63. Diamond M, Chen R, Xie X, Case J, Zhang X, VanBlargan L, Liu Y, Liu J, Errico J, Winkler E, Suryadevara N, Tahan S, Turner J, Kim W, Schmitz A, Thapa M, Wang D, Boon A, Pinto D, Presti R, O'Halloran J, Kim A, Deepak P, Fremont D, Corti D, Virgin H, Crowe J, Droit L, Ellebedy A, Shi PY, Gilchuk P. SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies. Res Sq. 2021 Feb 10. PMID: 33594356.
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    64. Suryadevara N, Shrihari S, Gilchuk P, VanBlargan LA, Binshtein E, Zost SJ, Nargi RS, Sutton RE, Winkler ES, Chen EC, Fouch ME, Davidson E, Doranz BJ, Carnahan RH, Thackray LB, Diamond MS, Crowe JE. Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein. bioRxiv. 2021 Jan 20. PMID: 33501445.
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    65. Dagotto G, Mercado NB, Martinez DR, Hou YJ, Nkolola JP, Carnahan RH, Crowe JE, Baric RS, Barouch DH. Comparison of Subgenomic and Total RNA in SARS-CoV-2 Challenged Rhesus Macaques. J Virol. 2021 Jan 20. PMID: 33472939.
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    66. Winkler ES, Gilchuk P, Yu J, Bailey AL, Chen RE, Zost SJ, Jang H, Huang Y, Allen JD, Case JB, Sutton RE, Carnahan RH, Darling TL, Boon ACM, Mack M, Head RD, Ross TM, Crowe JE, Diamond MS. Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection. bioRxiv. 2020 Dec 28. PMID: 33398272.
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    67. Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, Suryadevara N, Chen RE, Martinez DR, Nargi RS, Sutton RE, Ledgerwood JE, Graham BS, Diamond MS, Haynes BF, Acharya P, Carnahan RH, Crowe JE, Baric RS, Morris L, McLellan JS, Georgiev IS. Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions. bioRxiv. 2020 Dec 20. PMID: 33398266.
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    68. Jones T, Day SB, Myers L, Crowe JE, Soto C. ClonoMatch: a tool for identifying homologous immunoglobulin and T cell receptor sequences in large databases. Bioinformatics. 2020 Dec 16. PMID: 33325481.
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    69. Dong J, Cross RW, Doyle MP, Kose N, Mousa JJ, Annand EJ, Borisevich V, Agans KN, Sutton R, Nargi R, Majedi M, Fenton KA, Reichard W, Bombardi RG, Geisbert TW, Crowe JE. Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein. Cell. 2020 12 10; 183(6):1536-1550.e17. PMID: 33306954.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    70. Williamson LE, Gilliland T, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe JE. Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection. Cell. 2020 12 23; 183(7):1884-1900.e23. PMID: 33301709.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    71. Bozhanova NG, Sangha AK, Sevy AM, Gilchuk P, Huang K, Nargi RS, Reidy JX, Trivette A, Carnahan RH, Bukreyev A, Crowe JE, Meiler J. Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31142-31148. PMID: 33229516.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    72. Greaney AJ, Starr TN, Gilchuk P, Zost SJ, Binshtein E, Loes AN, Hilton SK, Huddleston J, Eguia R, Crawford KHD, Dingens AS, Nargi RS, Sutton RE, Suryadevara N, Rothlauf PW, Liu Z, Whelan SPJ, Carnahan RH, Crowe JE, Bloom JD. Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition. Cell Host Microbe. 2021 01 13; 29(1):44-57.e9. PMID: 33259788.
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    73. Wessel AW, Kose N, Bombardi RG, Roy V, Chantima W, Mongkolsapaya J, Edeling MA, Nelson CA, Bosch I, Alter G, Screaton GR, Fremont DH, Crowe JE, Diamond MS. Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy. Nat Commun. 2020 10 19; 11(1):5278. PMID: 33077712.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    74. Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE, Hu WT, Lee FE, Sanz I. Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19. Nat Immunol. 2020 12; 21(12):1506-1516. PMID: 33028979.
      Citations: 148     Fields:    Translation:HumansCells
    75. Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Crowe JE, Coffey RJ. Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein. Gastroenterology. 2021 02; 160(3):958-961.e3. PMID: 33022277.
      Citations: 12     Fields:    Translation:HumansCells
    76. Greaney AJ, Starr TN, Gilchuk P, Zost SJ, Binshtein E, Loes AN, Hilton SK, Huddleston J, Eguia R, Crawford KHD, Dingens AS, Nargi RS, Sutton RE, Suryadevara N, Rothlauf PW, Liu Z, Whelan SPJ, Carnahan RH, Crowe JE, Bloom JD. Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition. bioRxiv. 2020 Sep 28. PMID: 32935107.
      Citations:    
    77. Reif DM, Chanock SJ, Edwards KM, Crowe JE. Inappropriate Citation of Vaccine Article. J Infect Dis. 2020 09 14; 222(8):1413-1414. PMID: 31158294.
      Citations:    Fields:    Translation:HumansPHPublic Health
    78. Dong J, Gilchuk I, Li S, Irving R, Goff MT, Turner HL, Ward AB, Carnahan RH, Crowe JE. Anti-influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface. J Clin Invest. 2020 09 01; 130(9):4734-4739. PMID: 32749241.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    79. Finn JA, Dong J, Sevy AM, Parrish E, Gilchuk I, Nargi R, Scarlett-Jones M, Reichard W, Bombardi R, Voss TG, Meiler J, Crowe JE. Identification of Structurally Related Antibodies in Antibody Sequence Databases Using Rosetta-Derived Position-Specific Scoring. Structure. 2020 10 06; 28(10):1124-1130.e5. PMID: 32783953.
      Citations: 4     Fields:    Translation:HumansCells
    80. Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe JE. Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe. 2020 11 11; 28(5):699-711.e7. PMID: 32783883.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    81. Fox JM, Huang L, Tahan S, Powell LA, Crowe JE, Wang D, Diamond MS. A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice. PLoS Pathog. 2020 08; 16(8):e1008743. PMID: 32760128.
      Citations: 3     Fields:    Translation:AnimalsCells
    82. Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE, Van Hoeven N, Thackray LB, Carnahan RH. Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics. Nat Biomed Eng. 2020 11; 4(11):1030-1043. PMID: 32747832.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    83. Soto C, Finn JA, Willis JR, Day SB, Sinkovits RS, Jones T, Schmitz S, Meiler J, Branchizio A, Crowe JE. PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST. BMC Bioinformatics. 2020 Jul 16; 21(1):314. PMID: 32677886.
      Citations: 5     Fields:    Translation:HumansCells
    84. Engdahl TB, Crowe JE. Humoral Immunity to Hantavirus Infection. mSphere. 2020 07 15; 5(4). PMID: 32669473.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    85. Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020 08; 584(7821):443-449. PMID: 32668443.
      Citations: 372     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    86. Soto C, Bombardi RG, Kozhevnikov M, Sinkovits RS, Chen EC, Branchizio A, Kose N, Day SB, Pilkinton M, Gujral M, Mallal S, Crowe JE. High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires. Cell Rep. 2020 07 14; 32(2):107882. PMID: 32668251.
      Citations: 10     Fields:    Translation:HumansCells
    87. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Nat Med. 2020 09; 26(9):1422-1427. PMID: 32651581.
      Citations: 179     Fields:    Translation:HumansCellsPHPublic Health
    88. Chen EC, Rubinstein S, Soto C, Bombardi RG, Day SB, Myers L, Zaytsev A, Majedi M, Cornell RF, Crowe JE. Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis. PLoS One. 2020; 15(7):e0235713. PMID: 32634163.
      Citations:    Fields:    Translation:HumansCells
    89. Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe JE. Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Sci Immunol. 2020 07 03; 5(49). PMID: 32620559.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    90. Sevy AM, Gilchuk IM, Brown BP, Bozhanova NG, Nargi R, Jensen M, Meiler J, Crowe JE. Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants. Structure. 2020 10 06; 28(10):1114-1123.e4. PMID: 32610044.
      Citations: 4     Fields:    Translation:AnimalsCells
    91. Erasmus JH, Archer J, Fuerte-Stone J, Khandhar AP, Voigt E, Granger B, Bombardi RG, Govero J, Tan Q, Durnell LA, Coler RN, Diamond MS, Crowe JE, Reed SG, Thackray LB, Carnahan RH, Van Hoeven N. Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection. Mol Ther Methods Clin Dev. 2020 Sep 11; 18:402-414. PMID: 32695842.
      Citations: 12     
    92. Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, Martinez DR, Schäfer A, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals. bioRxiv. 2020 May 22. PMID: 32511409.
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    93. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Lee FE, Nguyen DC, Sanz I, Martinez DR, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. bioRxiv. 2020 May 13. PMID: 32511414.
      Citations:    
    94. Young E, Carnahan RH, Andrade DV, Kose N, Nargi RS, Fritch EJ, Munt JE, Doyle MP, White L, Baric TJ, Stoops M, DeSilva A, Tse LV, Martinez DR, Zhu D, Metz S, Wong MP, Espinosa DA, Montoya M, Biering SB, Sukulpolvi-Petty S, Kuan G, Balmaseda A, Diamond MS, Harris E, Crowe JE, Baric RS. Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies. Cell Host Microbe. 2020 05 13; 27(5):710-724.e7. PMID: 32407709.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    95. Powell LA, Fox JM, Kose N, Kim AS, Majedi M, Bombardi R, Carnahan RH, Slaughter JC, Morrison TE, Diamond MS, Crowe JE. Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease. PLoS Pathog. 2020 05; 16(5):e1008517. PMID: 32365139.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    96. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. Correction: Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 04; 16(4):e1008545. PMID: 32348355.
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    97. Ilinykh PA, Huang K, Santos RI, Gilchuk P, Gunn BM, Karim MM, Liang J, Fouch ME, Davidson E, Parekh DV, Kimble JB, Pietzsch CA, Meyer M, Kuzmina NA, Zeitlin L, Saphire EO, Alter G, Crowe JE, Bukreyev A. Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host Microbe. 2020 06 10; 27(6):976-991.e11. PMID: 32320678.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    98. Hirsch J, Faber BW, Crowe JE, Verstrepen B, Cornelissen G. E. coli production process yields stable dengue 1 virus-sized particles (VSPs). Vaccine. 2020 04 09; 38(17):3305-3312. PMID: 32197924.
      Citations: 2     Fields:    Translation:AnimalsCells
    99. Sauer MF, Sevy AM, Crowe JE, Meiler J. Multi-state design of flexible proteins predicts sequences optimal for conformational change. PLoS Comput Biol. 2020 02; 16(2):e1007339. PMID: 32032348.
      Citations: 5     Fields:    Translation:Cells
    100. Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. 2020 02 18; 52(2):388-403.e12. PMID: 32023489.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    101. Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE, Diamond MS, Fremont DH. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 2020 02 03; 217(2). PMID: 31757867.
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    102. Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE. Correction: Tissue-Specific Expressed Antibody Variable Gene Repertoires. PLoS One. 2020; 15(1):e0228412. PMID: 31978140.
      Citations:    Fields:    
    103. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 01; 16(1):e1008103. PMID: 31945137.
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    104. Ho BJ, Crowe JE, Dorfman SR, Camp EA, Yusuf S, Shenoi RP. Correlation of clinical and chest radiograph findings in pediatric submersion cases. Pediatr Radiol. 2020 04; 50(4):492-500. PMID: 31897567.
      Citations:    Fields:    Translation:Humans
    105. Schmitz S, Soto C, Crowe JE, Meiler J. Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires. MAbs. 2020 Jan-Dec; 12(1):1758291. PMID: 32397786.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    106. Sevy AM, Soto C, Bombardi RG, Meiler J, Crowe JE. Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures. BMC Bioinformatics. 2019 Dec 04; 20(1):629. PMID: 31801472.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    107. Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE. Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice. Cell Host Microbe. 2019 12 11; 26(6):715-728.e8. PMID: 31757769.
      Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    108. Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA. Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe. 2019 12 11; 26(6):729-738.e4. PMID: 31757767.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    109. Velayutham TS, Kumar S, Zhang X, Kose N, Walker DH, Winslow G, Crowe JE, McBride JW. Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization. Infect Immun. 2019 12; 87(12). PMID: 31548319.
      Citations: 6     Fields:    Translation:HumansCells
    110. Martinez Viedma MDP, Kose N, Parham L, Balmaseda A, Kuan G, Lorenzana I, Harris E, Crowe JE, Pickett BE. Peptide arrays of three collections of human sera from patients infected with mosquito-borne viruses. F1000Res. 2019; 8:1875. PMID: 32201571.
      Citations: 3     Fields:    
    111. Cable J, Srikantiah P, Crowe JE, Pulendran B, Hill A, Ginsberg A, Koff W, Mathew A, Ng T, Jansen K, Glenn G, Permar S, Wilson I, Weiner DB, Weissman D, Rappuoli R. Vaccine innovations for emerging infectious diseases-a symposium report. Ann N Y Acad Sci. 2020 02; 1462(1):14-26. PMID: 31659752.
      Citations: 5     Fields:    Translation:HumansAnimalsPHPublic Health
    112. Bennett MR, Dong J, Bombardi RG, Soto C, Parrington HM, Nargi RS, Schoeder CT, Nagel MB, Schey KL, Meiler J, Skaar EP, Crowe JE. Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis. mBio. 2019 10 22; 10(5). PMID: 31641091.
      Citations: 6     Fields:    Translation:HumansCells
    113. Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE, Joyce S, Wilson JT. Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells. ACS Nano. 2019 10 22; 13(10):10939-10960. PMID: 31553872.
      Citations: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    114. Kinchen VJ, Massaccesi G, Flyak AI, Mankowski MC, Colbert MD, Osburn WO, Ray SC, Cox AL, Crowe JE, Bailey JR. Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatitis C virus clearance. J Clin Invest. 2019 08 13; 129(11):4786-4796. PMID: 31408439.
      Citations: 9     Fields:    Translation:HumansCells
    115. Colbert MD, Flyak AI, Ogega CO, Kinchen VJ, Massaccesi G, Hernandez M, Davidson E, Doranz BJ, Cox AL, Crowe JE, Bailey JR. Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2. J Virol. 2019 07 15; 93(14). PMID: 31068427.
      Citations: 15     Fields:    Translation:HumansCells
    116. Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE. A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection. Sci Immunol. 2019 05 17; 4(35). PMID: 31101672.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    117. Bangaru S, Lang S, Schotsaert M, Vanderven HA, Zhu X, Kose N, Bombardi R, Finn JA, Kent SJ, Gilchuk P, Gilchuk I, Turner HL, García-Sastre A, Li S, Ward AB, Wilson IA, Crowe JE. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 2019 05 16; 177(5):1136-1152.e18. PMID: 31100268.
      Citations: 84     Fields:    Translation:AnimalsCells
    118. King LB, West BR, Moyer CL, Gilchuk P, Flyak A, Ilinykh PA, Bombardi R, Hui S, Huang K, Bukreyev A, Crowe JE, Saphire EO. Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun. 2019 04 17; 10(1):1788. PMID: 30996276.
      Citations: 10     Fields:    Translation:HumansCells
    119. Crowe JE. Antibody Determinants of Influenza Immunity. J Infect Dis. 2019 04 08; 219(Suppl_1):S21-S29. PMID: 30715373.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    120. Bennett MR, Bombardi RG, Kose N, Parrish EH, Nagel MB, Petit RA, Read TD, Schey KL, Thomsen IP, Skaar EP, Crowe JE. Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms. J Infect Dis. 2019 04 08; 219(8):1264-1273. PMID: 30496483.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    121. Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE. Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection. J Virol. 2019 04 15; 93(8). PMID: 30728263.
      Citations: 9     Fields:    Translation:HumansCells
    122. Dong J, Finn JA, Larsen PA, Smith TPL, Crowe JE. Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol. 2019; 10:558. PMID: 30967877.
      Citations: 13     Fields:    Translation:AnimalsCells
    123. Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE. High frequency of shared clonotypes in human B cell receptor repertoires. Nature. 2019 02; 566(7744):398-402. PMID: 30760926.
      Citations: 85     Fields:    Translation:HumansCells
    124. Engelhardt BG, Savani U, Jung DK, Powers AC, Jagasia M, Chen H, Winnick JJ, Tamboli RA, Crowe JE, Abumrad NN. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biol Blood Marrow Transplant. 2019 06; 25(6):1225-1231. PMID: 30738170.
      Citations: 6     Fields:    Translation:Humans
    125. Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE, Screaton GR, Diamond MS. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Rep. 2019 02 05; 26(6):1585-1597.e4. PMID: 30726740.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    126. Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, Bukreyev A. Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine. J Virol. 2019 02 15; 93(4). PMID: 30518655.
      Citations: 4     Fields:    Translation:AnimalsCells
    127. Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB. Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. PLoS Biol. 2019 02; 17(2):e3000139. PMID: 30716060.
      Citations: 19     Fields:    Translation:AnimalsCells
    128. Crowe JE. Influenza Virus-Specific Human Antibody Repertoire Studies. J Immunol. 2019 01 15; 202(2):368-373. PMID: 30617118.
      Citations: 5     Fields:    Translation:HumansCells
    129. Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE, Rossmann MG. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1591-1596. PMID: 30642974.
      Citations: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    130. Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1597-1602. PMID: 30642961.
      Citations: 12     Fields:    Translation:HumansCells
    131. Vogt MR, Crowe JE. Current Understanding of Humoral Immunity to Enterovirus D68. J Pediatric Infect Dis Soc. 2018 Dec 26; 7(suppl_2):S49-S53. PMID: 30590621.
      Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    132. Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE. Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth. PLoS One. 2018; 13(12):e0209437. PMID: 30566528.
      Citations: 5     Fields:    Translation:HumansCells
    133. Gilchuk P, Mire CE, Geisbert JB, Agans KN, Deer DJ, Cross RW, Slaughter JC, Flyak AI, Mani J, Pauly MH, Velasco J, Whaley KJ, Zeitlin L, Geisbert TW, Crowe JE. Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates. J Infect Dis. 2018 11 22; 218(suppl_5):S565-S573. PMID: 29982718.
      Citations: 6     Fields:    Translation:Animals
    134. Ilinykh PA, Graber J, Kuzmina NA, Huang K, Ksiazek TG, Crowe JE, Bukreyev A. Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies. J Infect Dis. 2018 11 22; 218(suppl_5):S418-S422. PMID: 30060231.
      Citations: 3     Fields:    Translation:AnimalsCells
    135. Wirawan M, Fibriansah G, Marzinek JK, Lim XX, Ng TS, Sim AYL, Zhang Q, Kostyuchenko VA, Shi J, Smith SA, Verma CS, Anand G, Crowe JE, Bond PJ, Lok SM. Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure. 2019 02 05; 27(2):253-267.e8. PMID: 30471923.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    136. Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nat Microbiol. 2019 01; 4(1):187-197. PMID: 30455470.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    137. Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE, Pierson TC. A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions. Nat Microbiol. 2019 01; 4(1):71-77. PMID: 30455471.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    138. Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE, Bjorkman PJ, Shaw GM, Bailey JR. Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection. Cell Host Microbe. 2018 11 14; 24(5):717-730.e5. PMID: 30439341.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    139. Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ. HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe. 2018 11 14; 24(5):703-716.e3. PMID: 30439340.
      Citations: 50     Fields:    Translation:HumansCells
    140. Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, Kobinger GP, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB. In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Rep. 2018 11 13; 25(7):1982-1993.e4. PMID: 30428362.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    141. Tsai WY, Chen HL, Tsai JJ, Dejnirattisai W, Jumnainsong A, Mongkolsapaya J, Screaton G, Crowe JE, Wang WK. Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Virus Particles: Implication for Novel Strategy for Dengue Vaccine. J Virol. 2018 12 01; 92(23). PMID: 30185598.
      Citations: 14     Fields:    Translation:HumansCells
    142. Bramble MS, Hoff N, Gilchuk P, Mukadi P, Lu K, Doshi RH, Steffen I, Nicholson BP, Lipson A, Vashist N, Sinai C, Spencer D, Olinger G, Wemakoy EO, Illunga BK, Pettitt J, Logue J, Marchand J, Varughese J, Bennett RS, Jahrling P, Cavet G, Serafini T, Ollmann Saphire E, Vilain E, Muyembe-Tamfum JJ, Hensely LE, Simmons G, Crowe JE, Rimoin AW. Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors. J Infect Dis. 2018 11 05; 218(12):1929-1936. PMID: 30107445.
      Citations: 11     Fields:    Translation:HumansCells
    143. Alvarado G, Ettayebi K, Atmar RL, Bombardi RG, Kose N, Estes MK, Crowe JE. Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses. Gastroenterology. 2018 12; 155(6):1898-1907. PMID: 30170116.
      Citations: 31     Fields:    Translation:HumansCells
    144. Ilinykh PA, Santos RI, Gunn BM, Kuzmina NA, Shen X, Huang K, Gilchuk P, Flyak AI, Younan P, Alter G, Crowe JE, Bukreyev A. Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap. PLoS Pathog. 2018 08; 14(8):e1007204. PMID: 30138408.
      Citations: 10     Fields:    Translation:HumansCells
    145. Meyer M, Yoshida A, Ramanathan P, Saphire EO, Collins PL, Crowe JE, Samal S, Bukreyev A. Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors. Cell Rep. 2018 08 14; 24(7):1816-1829. PMID: 30110638.
      Citations: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    146. Kuzmina NA, Younan P, Gilchuk P, Santos RI, Flyak AI, Ilinykh PA, Huang K, Lubaki NM, Ramanathan P, Crowe JE, Bukreyev A. Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors. Cell Rep. 2018 08 14; 24(7):1802-1815.e5. PMID: 30110637.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    147. Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 2018 08 09; 174(4):938-952.e13. PMID: 30096313.
      Citations: 98     Fields:    Translation:AnimalsCellsPHPublic Health
    148. Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE, Lauffenburger D, Kawaoka Y, Kobinger GP, Andersen KG, Dye JM, Saphire EO, Alter G. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host Microbe. 2018 08 08; 24(2):221-233.e5. PMID: 30092199.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    149. Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. 2018 08 21; 49(2):363-374.e10. PMID: 30029854.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    150. Bangaru S, Zhang H, Gilchuk IM, Voss TG, Irving RP, Gilchuk P, Matta P, Zhu X, Lang S, Nieusma T, Richt JA, Albrecht RA, Vanderven HA, Bombardi R, Kent SJ, Ward AB, Wilson IA, Crowe JE. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun. 2018 07 10; 9(1):2669. PMID: 29991715.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    151. Crowe JE. Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine. Cold Spring Harb Perspect Biol. 2018 07 02; 10(7). PMID: 28663208.
      Citations: 10     Fields:    Translation:Humans
    152. Setliff I, McDonnell WJ, Raju N, Bombardi RG, Murji AA, Scheepers C, Ziki R, Mynhardt C, Shepherd BE, Mamchak AA, Garrett N, Karim SA, Mallal SA, Crowe JE, Morris L, Georgiev IS. Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host Microbe. 2018 06 13; 23(6):845-854.e6. PMID: 29861170.
      Citations: 36     Fields:    Translation:HumansCells
    153. Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS. Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. 2018 05; 557(7706):570-574. PMID: 29769725.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    154. Flyak AI, Kuzmina N, Murin CD, Bryan C, Davidson E, Gilchuk P, Gulka CP, Ilinykh PA, Shen X, Huang K, Ramanathan P, Turner H, Fusco ML, Lampley R, Kose N, King H, Sapparapu G, Doranz BJ, Ksiazek TG, Wright DW, Saphire EO, Ward AB, Bukreyev A, Crowe JE. Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region. Nat Microbiol. 2018 06; 3(6):670-677. PMID: 29736037.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    155. Lecouturier V, Berry C, Saulnier A, Naville S, Manin C, Girerd-Chambaz Y, Crowe JE, Jackson N, Guy B. Characterization of recombinant yellow fever-dengue vaccine viruses with human monoclonal antibodies targeting key conformational epitopes. Vaccine. 2019 07 26; 37(32):4601-4609. PMID: 29706291.
      Citations: 2     Fields:    
    156. Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE, Diamond MS. Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus. mBio. 2018 02 27; 9(1). PMID: 29487230.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    157. Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE. Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. PLoS Pathog. 2018 02; 14(2):e1006837. PMID: 29470533.
      Citations: 15     Fields:    Translation:HumansCells
    158. Sevy AM, Panda S, Crowe JE, Meiler J, Vorobeychik Y. Integrating linear optimization with structural modeling to increase HIV neutralization breadth. PLoS Comput Biol. 2018 02; 14(2):e1005999. PMID: 29451898.
      Citations: 3     Fields:    Translation:HumansCells
    159. King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO. The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding. Cell Host Microbe. 2018 Jan 10; 23(1):101-109.e4. PMID: 29324225.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    160. Mankowski MC, Kinchen VJ, Wasilewski LN, Flyak AI, Ray SC, Crowe JE, Bailey JR. Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):E82-E91. PMID: 29255018.
      Citations: 29     Fields:    Translation:HumansCells
    161. Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, Martini SR, de Silva AD, Ricciardi MJ, Magnani DM, Silveira CGT, Maestri A, Costa PR, de-Oliveira-Pinto LM, de Azeredo EL, Damasco PV, Phillips E, Mallal S, de Silva AM, Collins M, Durbin A, Diehl SA, Cerpas C, Balmaseda A, Kuan G, Coloma J, Harris E, Crowe JE, Stone M, Norris PJ, Busch M, Vivanco-Cid H, Cox J, Graham BS, Ledgerwood JE, Turtle L, Solomon T, Kallas EG, Watkins DI, Weiskopf D, Sette A. Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans. J Virol. 2017 12 15; 91(24). PMID: 28978707.
      Citations: 93     Fields:    Translation:HumansCells
    162. Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure. 2017 12 05; 25(12):1820-1828.e2. PMID: 29153506.
      Citations: 4     Fields:    Translation:Cells
    163. Matho MH, Schlossman A, Gilchuk IM, Miller G, Mikulski Z, Hupfer M, Wang J, Bitra A, Meng X, Xiang Y, Kaever T, Doukov T, Ley K, Crotty S, Peters B, Hsieh-Wilson LC, Crowe JE, Zajonc DM. Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8. J Biol Chem. 2018 01 05; 293(1):390-401. PMID: 29123031.
      Citations: 3     Fields:    Translation:HumansCells
    164. Lim XX, Chandramohan A, Lim XE, Crowe JE, Lok SM, Anand GS. Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface. Structure. 2017 09 05; 25(9):1391-1402.e3. PMID: 28823471.
      Citations: 19     Fields:    Translation:HumansCells
    165. Crowe JE. Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design. Cell Host Microbe. 2017 Aug 09; 22(2):193-206. PMID: 28799905.
      Citations: 32     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    166. Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE, Diamond MS, Streblow DN. Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005637. PMID: 28628616.
      Citations: 22     Fields:    Translation:AnimalsCells
    167. Bailey JR, Flyak AI, Cohen VJ, Li H, Wasilewski LN, Snider AE, Wang S, Learn GH, Kose N, Loerinc L, Lampley R, Cox AL, Pfaff JM, Doranz BJ, Shaw GM, Ray SC, Crowe JE. Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance. JCI Insight. 2017 May 04; 2(9). PMID: 28469084.
      Citations: 58     Fields:    
    168. Crowe JE. Treating Flu with Skin of Frog. Immunity. 2017 04 18; 46(4):517-518. PMID: 28423328.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    169. Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE, Zeitlin L, Geisbert TW. Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Sci Transl Med. 2017 04 05; 9(384). PMID: 28381540.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    170. Thomsen IP, Sapparapu G, James DBA, Cassat JE, Nagarsheth M, Kose N, Putnam N, Boguslawski KM, Jones LS, Wood JB, Creech CB, Torres VJ, Crowe JE. Monoclonal Antibodies Against the Staphylococcus aureus Bicomponent Leukotoxin AB Isolated Following Invasive Human Infection Reveal Diverse Binding and Modes of Action. J Infect Dis. 2017 04 01; 215(7):1124-1131. PMID: 28186295.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    171. Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE, Kuhn RJ, Rossmann MG. A human antibody against Zika virus crosslinks the E protein to prevent infection. Nat Commun. 2017 03 16; 8:14722. PMID: 28300075.
      Citations: 59     Fields:    Translation:HumansCells
    172. Nivarthi UK, Kose N, Sapparapu G, Widman D, Gallichotte E, Pfaff JM, Doranz BJ, Weiskopf D, Sette A, Durbin AP, Whitehead SS, Baric R, Crowe JE, de Silva AM. Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination. J Virol. 2017 03 01; 91(5). PMID: 28031369.
      Citations: 33     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    173. Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE, Lenschow DJ, Diamond MS. Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis. Sci Transl Med. 2017 02 01; 9(375). PMID: 28148840.
      Citations: 25     Fields:    Translation:AnimalsCells
    174. Mousa JJ, Kose N, Matta P, Gilchuk P, Crowe JE. A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncytial virus fusion protein. Nat Microbiol. 2017 Jan 30; 2:16271. PMID: 28134924.
      Citations: 38     Fields:    Translation:HumansCells
    175. Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE, Jardetzky TS. Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Nat Microbiol. 2017 Jan 30; 2:16272. PMID: 28134915.
      Citations: 30     Fields:    Translation:Cells
    176. Sapparapu G, Fernandez E, Kose N, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE. Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. Nature. 2016 12 15; 540(7633):443-447. PMID: 27819683.
      Citations: 205     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    177. Gilchuk I, Gilchuk P, Sapparapu G, Lampley R, Singh V, Kose N, Blum DL, Hughes LJ, Satheshkumar PS, Townsend MB, Kondas AV, Reed Z, Weiner Z, Olson VA, Hammarlund E, Raue HP, Slifka MK, Slaughter JC, Graham BS, Edwards KM, Eisenberg RJ, Cohen GH, Joyce S, Crowe JE. Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections. Cell. 2016 Oct 20; 167(3):684-694.e9. PMID: 27768891.
      Citations: 23     Fields:    Translation:HumansCells
    178. Mousa JJ, Sauer MF, Sevy AM, Finn JA, Bates JT, Alvarado G, King HG, Loerinc LB, Fong RH, Doranz BJ, Correia BE, Kalyuzhniy O, Wen X, Jardetzky TS, Schief WR, Ohi MD, Meiler J, Crowe JE. Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):E6849-E6858. PMID: 27791117.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    179. Culotta PA, Crowe JE, Tran QA, Jones JY, Mehollin-Ray AR, Tran HB, Donaruma-Kwoh M, Dodge CT, Camp EA, Cruz AT. Performance of computed tomography of the head to evaluate for skull fractures in infants with suspected non-accidental trauma. Pediatr Radiol. 2017 Jan; 47(1):74-81. PMID: 27744559.
      Citations: 4     Fields:    Translation:Humans
    180. Shanker S, Czakó R, Sapparapu G, Alvarado G, Viskovska M, Sankaran B, Atmar RL, Crowe JE, Estes MK, Prasad BV. Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):E5830-E5837. PMID: 27647885.
      Citations: 24     Fields:    Translation:HumansCells
    181. Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE, Aman MJ, Dye JM, Lai JR, Chandran K. A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses. Science. 2016 10 21; 354(6310):350-354. PMID: 27608667.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    182. Crowe JE. Teaching a Clone to Walk, One Step at a Time. Cell. 2016 Sep 08; 166(6):1360-1361. PMID: 27610559.
      Citations: 2     Fields:    Translation:HumansCells
    183. Verma A, Basile AO, Bradford Y, Kuivaniemi H, Tromp G, Carey D, Gerhard GS, Crowe JE, Ritchie MD, Pendergrass SA. Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases. PLoS One. 2016; 11(8):e0160573. PMID: 27508393.
      Citations: 12     Fields:    Translation:Humans
    184. Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB. Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol. 2016 Aug 08; 1(9):16128. PMID: 27562261.
      Citations: 55     Fields:    Translation:HumansCells
    185. Hawman DW, Fox JM, Ashbrook AW, May NA, Schroeder KMS, Torres RM, Crowe JE, Dermody TS, Diamond MS, Morrison TE. Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence. Cell Rep. 2016 08 02; 16(5):1326-1338. PMID: 27452455.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    186. Hicar MD, Chen X, Sulli C, Barnes T, Goodman J, Sojar H, Briney B, Willis J, Chukwuma VU, Kalams SA, Doranz BJ, Spearman P, Crowe JE. Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein. PLoS One. 2016; 11(7):e0158861. PMID: 27411063.
      Citations: 2     Fields:    Translation:HumansCells
    187. Cho MJ, Ellebrecht CT, Hammers CM, Mukherjee EM, Sapparapu G, Boudreaux CE, McDonald SM, Crowe JE, Payne AS. Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6. J Immunol. 2016 08 15; 197(4):1065-73. PMID: 27402694.
      Citations: 11     Fields:    Translation:Humans
    188. Bangaru S, Nieusma T, Kose N, Thornburg NJ, Finn JA, Kaplan BS, King HG, Singh V, Lampley RM, Sapparapu G, Cisneros A, Edwards KM, Slaughter JC, Edupuganti S, Lai L, Richt JA, Webby RJ, Ward AB, Crowe JE. Recognition of influenza H3N2 variant virus by human neutralizing antibodies. JCI Insight. 2016 Jul 07; 1(10). PMID: 27482543.
      Citations: 12     Fields:    
    189. Sapparapu G, Czakó R, Alvarado G, Shanker S, Prasad BV, Atmar RL, Estes MK, Crowe JE. Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding. PLoS Pathog. 2016 06; 12(6):e1005719. PMID: 27355511.
      Citations: 15     Fields:    Translation:HumansCells
    190. Wen X, Pickens J, Mousa JJ, Leser GP, Lamb RA, Crowe JE, Jardetzky TS. A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV. PLoS One. 2016; 11(5):e0155917. PMID: 27224013.
      Citations: 6     Fields:    Translation:AnimalsCells
    191. Boehme KW, Ikizler M, Iskarpatyoti JA, Wetzel JD, Willis J, Crowe JE, LaBranche CC, Montefiori DC, Wilson GJ, Dermody TS. Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1. mSphere. 2016 May-Jun; 1(3). PMID: 27303748.
      Citations: 4     Fields:    
    192. Finn JA, Koehler Leman J, Willis JR, Cisneros A, Crowe JE, Meiler J. Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints. PLoS One. 2016; 11(5):e0154811. PMID: 27182833.
      Citations: 11     Fields:    Translation:Cells
    193. Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS. Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1. J Virol. 2016 May 15; 90(10):5090-5097. PMID: 26962223.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    194. Boyd SD, Crowe JE. Deep sequencing and human antibody repertoire analysis. Curr Opin Immunol. 2016 06; 40:103-9. PMID: 27065089.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    195. Clark KB, Hsiao HM, Bassit L, Crowe JE, Schinazi RF, Perng GC, Villinger F. Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells. Virology. 2016 06; 493:162-72. PMID: 27058763.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    196. Willis JR, Finn JA, Briney B, Sapparapu G, Singh V, King H, LaBranche CC, Montefiori DC, Meiler J, Crowe JE. Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4446-51. PMID: 27044078.
      Citations: 15     Fields:    Translation:HumansCells
    197. Ilinykh PA, Shen X, Flyak AI, Kuzmina N, Ksiazek TG, Crowe JE, Bukreyev A. Chimeric Filoviruses for Identification and Characterization of Monoclonal Antibodies. J Virol. 2016 Apr; 90(8):3890-3901. PMID: 26819310.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    198. Thornburg NJ, Zhang H, Bangaru S, Sapparapu G, Kose N, Lampley RM, Bombardi RG, Yu Y, Graham S, Branchizio A, Yoder SM, Rock MT, Creech CB, Edwards KM, Lee D, Li S, Wilson IA, García-Sastre A, Albrecht RA, Crowe JE. H7N9 influenza virus neutralizing antibodies that possess few somatic mutations. J Clin Invest. 2016 Apr 01; 126(4):1482-94. PMID: 26950424.
      Citations: 36     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    199. Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE, Chandran K, Saphire EO. Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. mBio. 2016 Feb 23; 7(1):e02154-15. PMID: 26908579.
      Citations: 56     Fields:    Translation:HumansCells
    200. Engelhardt BG, Paczesny S, Jung DK, Daguindau E, Jagasia M, Savani BN, Chinratanalab W, Cornell RF, Goodman S, Greer JP, Kassim AA, Sengsayadeth S, Yoder SM, Rock MT, Crowe JE. Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation. Haematologica. 2016 05; 101(5):e204-8. PMID: 26819055.
      Citations:    Fields:    Translation:HumansCells
    201. Flyak AI, Shen X, Murin CD, Turner HL, David JA, Fusco ML, Lampley R, Kose N, Ilinykh PA, Kuzmina N, Branchizio A, King H, Brown L, Bryan C, Davidson E, Doranz BJ, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Saphire EO, Ward AB, Bukreyev A, Crowe JE. Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection. Cell. 2016 Jan 28; 164(3):392-405. PMID: 26806128.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    202. Bates JT, Pickens JA, Schuster JE, Johnson M, Tollefson SJ, Williams JV, Davis NL, Johnston RE, Schultz-Darken N, Slaughter JC, Smith-House F, Crowe JE. Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates. Vaccine. 2016 Feb 10; 34(7):950-6. PMID: 26772634.
      Citations: 12     Fields:    Translation:AnimalsCells
    203. Alvarado G, Crowe JE. Development of Human Monoclonal Antibodies Against Respiratory Syncytial Virus Using a High Efficiency Human Hybridoma Technique. Methods Mol Biol. 2016; 1442:63-76. PMID: 27464688.
      Citations: 3     Fields:    Translation:HumansCells
    204. Hicar MD, Chen X, Kalams SA, Sojar H, Landucci G, Forthal DN, Spearman P, Crowe JE. Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations. Mol Immunol. 2016 Feb; 70:94-103. PMID: 26748387.
      Citations: 5     Fields:    Translation:HumansCells
    205. Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS. Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress. Cell. 2015 Nov 19; 163(5):1095-1107. PMID: 26553503.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    206. Smith SA, Nivarthi UK, de Alwis R, Kose N, Sapparapu G, Bombardi R, Kahle KM, Pfaff JM, Lieberman S, Doranz BJ, de Silva AM, Crowe JE. Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site. J Virol. 2016 01 15; 90(2):780-9. PMID: 26512092.
      Citations: 24     Fields:    Translation:HumansCells
    207. Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE, Diamond MS, Rossmann MG. Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity. Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45):13898-903. PMID: 26504196.
      Citations: 23     Fields:    Translation:HumansCells
    208. Crowe JE, Koff WC. Deciphering the human immunome. Expert Rev Vaccines. 2015; 14(11):1421-5. PMID: 26485213.
      Citations: 5     Fields:    Translation:Humans
    209. Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE, de Silva AM, Ting JP. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1ß Secretion: A Primary Human Monocyte Model. PLoS One. 2015; 10(8):e0136708. PMID: 26301593.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    210. Chukwuma VU, Hicar MD, Chen X, Nicholas KJ, Joyner A, Kalams SA, Landucci G, Forthal DN, Spearman PW, Crowe JE. Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein. PLoS One. 2015; 10(7):e0133509. PMID: 26226263.
      Citations:    Fields:    Translation:HumansCells
    211. Winarski KL, Thornburg NJ, Yu Y, Sapparapu G, Crowe JE, Spiller BW. Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):9346-51. PMID: 26170302.
      Citations: 15     Fields:    Translation:HumansCells
    212. Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Khomadiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE. Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus. Cell Host Microbe. 2015 Jul 08; 18(1):86-95. PMID: 26159721.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    213. Sevy AM, Jacobs TM, Crowe JE, Meiler J. Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences. PLoS Comput Biol. 2015 Jul; 11(7):e1004300. PMID: 26147100.
      Citations: 19     Fields:    Translation:Cells
    214. Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JS, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM. DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Science. 2015 Jul 03; 349(6243):88-91. PMID: 26138979.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    215. Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE, Ting JP. Spleen Tyrosine Kinase (Syk) Mediates IL-1ß Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J Biol Chem. 2015 Jul 10; 290(28):17306-20. PMID: 26032420.
      Citations: 18     Fields:    Translation:HumansCells
    216. Willis JR, Sapparapu G, Murrell S, Julien JP, Singh V, King HG, Xia Y, Pickens JA, LaBranche CC, Slaughter JC, Montefiori DC, Wilson IA, Meiler J, Crowe JE. Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth. J Clin Invest. 2015 Jun; 125(6):2523-31. PMID: 25985274.
      Citations: 17     Fields:    Translation:HumansCells
    217. Simões EA, DeVincenzo JP, Boeckh M, Bont L, Crowe JE, Griffiths P, Hayden FG, Hodinka RL, Smyth RL, Spencer K, Thirstrup S, Walsh EE, Whitley RJ. Challenges and opportunities in developing respiratory syncytial virus therapeutics. J Infect Dis. 2015 Mar 15; 211 Suppl 1:S1-S20. PMID: 25713060.
      Citations: 44     Fields:    Translation:HumansCells
    218. Hashiguchi T, Fusco ML, Bornholdt ZA, Lee JE, Flyak AI, Matsuoka R, Kohda D, Yanagi Y, Hammel M, Crowe JE, Saphire EO. Structural basis for Marburg virus neutralization by a cross-reactive human antibody. Cell. 2015 Feb 26; 160(5):904-912. PMID: 25723165.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    219. Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE. Mechanism of human antibody-mediated neutralization of Marburg virus. Cell. 2015 Feb 26; 160(5):893-903. PMID: 25723164.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    220. Fibriansah G, Tan JL, Smith SA, de Alwis R, Ng TS, Kostyuchenko VA, Jadi RS, Kukkaro P, de Silva AM, Crowe JE, Lok SM. A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins. Nat Commun. 2015 Feb 20; 6:6341. PMID: 25698059.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    221. Smith SA, Crowe JE. Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies. Microbiol Spectr. 2015 Feb; 3(1):AID-0027-2014. PMID: 26104564.
      Citations: 31     Fields:    Translation:HumansCells
    222. Hooper KA, Crowe JE, Bloom JD. Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice. J Virol. 2015 Apr; 89(7):3737-45. PMID: 25609803.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    223. Hotard AL, Lee S, Currier MG, Crowe JE, Sakamoto K, Newcomb DC, Peebles RS, Plemper RK, Moore ML. Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis. J Virol. 2015 Jan; 89(1):512-22. PMID: 25339762.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    224. de Alwis R, Williams KL, Schmid MA, Lai CY, Patel B, Smith SA, Crowe JE, Wang WK, Harris E, de Silva AM. Dengue viruses are enhanced by distinct populations of serotype cross-reactive antibodies in human immune sera. PLoS Pathog. 2014 Oct; 10(10):e1004386. PMID: 25275316.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    225. Krause JC, Crowe JE. Committing the Oldest Sins in the Newest Kind of Ways-Antibodies Targeting the Influenza Virus Type A Hemagglutinin Globular Head. Microbiol Spectr. 2014 Oct; 2(5). PMID: 26104373.
      Citations: 7     Fields:    Translation:HumansCells
    226. Smith SA, de Alwis AR, Kose N, Jadi RS, de Silva AM, Crowe JE. Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clones. J Virol. 2014 Nov; 88(21):12233-41. PMID: 25100837.
      Citations: 59     Fields:    Translation:HumansCells
    227. Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE. Tissue-specific expressed antibody variable gene repertoires. PLoS One. 2014; 9(6):e100839. PMID: 24956460.
      Citations: 21     Fields:    Translation:HumansCells
    228. Dulek DE, Newcomb DC, Toki S, Goliniewska K, Cephus J, Reiss S, Bates JT, Crowe JE, Boyd KL, Moore ML, Zhou W, Peebles RS. STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge. J Virol. 2014 Sep 01; 88(17):9655-72. PMID: 24920804.
      Citations: 4     Fields:    Translation:AnimalsCells
    229. Almagro JC, Gilliland GL, Breden F, Scott JK, Sok D, Pauthner M, Reichert JM, Helguera G, Andrabi R, Mabry R, Bléry M, Voss JE, Laurén J, Abuqayyas L, Barghorn S, Ben-Jacob E, Crowe JE, Huston JS, Johnston SA, Krauland E, Lund-Johansen F, Marasco WA, Parren PW, Xu KY. Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA. MAbs. 2014 May-Jun; 6(3):577-618. PMID: 24589717.
      Citations: 3     Fields:    Translation:HumansAnimals
    230. Bates JT, Keefer CJ, Slaughter JC, Kulp DW, Schief WR, Crowe JE. Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein. Virology. 2014 Apr; 454-455:139-44. PMID: 24725940.
      Citations: 14     Fields:    Translation:HumansCells
    231. Correia BE, Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, Serra AM, Adachi Y, Holmes MA, Li Y, Klevit RE, Graham BS, Wyatt RT, Baker D, Strong RK, Crowe JE, Johnson PR, Schief WR. Proof of principle for epitope-focused vaccine design. Nature. 2014 Mar 13; 507(7491):201-6. PMID: 24499818.
      Citations: 219     Fields:    Translation:AnimalsCells
    232. Bisset GS, Crowe J. Diagnostic errors in interpretation of pediatric musculoskeletal radiographs at common injury sites. Pediatr Radiol. 2014 May; 44(5):552-7. PMID: 24445883.
      Citations: 5     Fields:    Translation:Humans
    233. Fibriansah G, Tan JL, Smith SA, de Alwis AR, Ng TS, Kostyuchenko VA, Ibarra KD, Wang J, Harris E, de Silva A, Crowe JE, Lok SM. A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface. EMBO Mol Med. 2014 03; 6(3):358-71. PMID: 24421336.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    234. Messer WB, de Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, de Silva AM, Baric RS. Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1939-44. PMID: 24385585.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    235. Alonas E, Lifland AW, Gudheti M, Vanover D, Jung J, Zurla C, Kirschman J, Fiore VF, Douglas A, Barker TH, Yi H, Wright ER, Crowe JE, Santangelo PJ. Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells. ACS Nano. 2014 Jan 28; 8(1):302-15. PMID: 24351207.
      Citations: 13     Fields:    Translation:HumansCells
    236. Smith SA, de Alwis AR, Kose N, Harris E, Ibarra KD, Kahle KM, Pfaff JM, Xiang X, Doranz BJ, de Silva AM, Austin SK, Sukupolvi-Petty S, Diamond MS, Crowe JE. The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein. mBio. 2013 Nov 19; 4(6):e00873-13. PMID: 24255124.
      Citations: 82     Fields:    Translation:HumansCells
    237. Sapparapu G, Sims AL, Aiyegbo MS, Shaikh FY, Harth EM, Crowe JE. Intracellular neutralization of a virus using a cell-penetrating molecular transporter. Nanomedicine (Lond). 2014 Aug; 9(11):1613-24. PMID: 24195674.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    238. Aiyegbo MS, Eli IM, Spiller BW, Williams DR, Kim R, Lee DE, Liu T, Li S, Stewart PL, Crowe JE. Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody. J Virol. 2014 Jan; 88(1):469-76. PMID: 24155406.
      Citations: 10     Fields:    Translation:Cells
    239. Finn JA, Crowe JE. Impact of new sequencing technologies on studies of the human B cell repertoire. Curr Opin Immunol. 2013 Oct; 25(5):613-8. PMID: 24161653.
      Citations: 17     Fields:    Translation:HumansCells
    240. Munden MM, Williams JL, Zhang W, Crowe JE, Munden RF, Cisek LJ. Intermittent testicular torsion in the pediatric patient: sonographic indicators of a difficult diagnosis. AJR Am J Roentgenol. 2013 Oct; 201(4):912-8. PMID: 24059384.
      Citations: 6     Fields:    Translation:Humans
    241. Hong M, Lee PS, Hoffman RM, Zhu X, Krause JC, Laursen NS, Yoon SI, Song L, Tussey L, Crowe JE, Ward AB, Wilson IA. Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. J Virol. 2013 Nov; 87(22):12471-80. PMID: 24027321.
      Citations: 82     Fields:    Translation:HumansCellsPHPublic Health
    242. Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE. Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. J Clin Invest. 2013 Oct; 123(10):4405-9. PMID: 23999429.
      Citations: 19     Fields:    Translation:HumansCellsPHPublic Health
    243. Crowe JE. Universal flu vaccines: primum non nocere. Sci Transl Med. 2013 Aug 28; 5(200):200fs34. PMID: 23986396.
      Citations: 12     Fields:    Translation:HumansCells
    244. Stone JW, Thornburg NJ, Blum DL, Kuhn SJ, Wright DW, Crowe JE. Gold nanorod vaccine for respiratory syncytial virus. Nanotechnology. 2013 Jul 26; 24(29):295102. PMID: 23799651.
      Citations: 23     Fields:    Translation:HumansCells
    245. Crowe JE. Immunology. Crowdsourcing immunity. Science. 2013 May 10; 340(6133):692-3. PMID: 23661747.
      Citations:    Fields:    Translation:HumansAnimalsCells
    246. Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL, Nannemann DP, Meiler J, Stewart PL, Crowe JE. Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. PLoS One. 2013; 8(5):e61101. PMID: 23671563.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    247. Willis JR, Briney BS, DeLuca SL, Crowe JE, Meiler J. Human germline antibody gene segments encode polyspecific antibodies. PLoS Comput Biol. 2013 Apr; 9(4):e1003045. PMID: 23637590.
      Citations: 36     Fields:    Translation:HumansCells
    248. Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE, Williams JV, Buus S, Sette A, Schumacher TN, Link AJ, Joyce S. Discovering naturally processed antigenic determinants that confer protective T cell immunity. J Clin Invest. 2013 May; 123(5):1976-87. PMID: 23543059.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    249. Smith SA, de Alwis R, Kose N, Durbin AP, Whitehead SS, de Silva AM, Crowe JE. Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics. J Infect Dis. 2013 Jun 15; 207(12):1898-908. PMID: 23526830.
      Citations: 45     Fields:    Translation:HumansCellsPHPublic Health
    250. Briney BS, Crowe JE. Secondary mechanisms of diversification in the human antibody repertoire. Front Immunol. 2013; 4:42. PMID: 23483107.
      Citations: 14     Fields:    
    251. Bates JT, Keefer CJ, Utley TJ, Correia BE, Schief WR, Crowe JE. Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency. J Immunol. 2013 Apr 01; 190(7):3732-9. PMID: 23455501.
      Citations: 11     Fields:    Translation:HumansCells
    252. Xu R, Krause JC, McBride R, Paulson JC, Crowe JE, Wilson IA. A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat Struct Mol Biol. 2013 Mar; 20(3):363-70. PMID: 23396351.
      Citations: 83     Fields:    Translation:HumansCells
    253. Zeitlin L, Bohorov O, Bohorova N, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Barnard DL, Bates JT, Crowe JE, Piedra PA, Gilbert BE. Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model. MAbs. 2013 Mar-Apr; 5(2):263-9. PMID: 23396091.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    254. Shaikh FY, Crowe JE. Molecular mechanisms driving respiratory syncytial virus assembly. Future Microbiol. 2013 Jan; 8(1):123-31. PMID: 23252497.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    255. Thornburg NJ, Hayward SL, Crowe JE. Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-?B. mBio. 2012 Dec 18; 3(6). PMID: 23249809.
      Citations: 46     Fields:    Translation:HumansCells
    256. Tsibane T, Ekiert DC, Krause JC, Martinez O, Crowe JE, Wilson IA, Basler CF. Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. PLoS Pathog. 2012; 8(12):e1003067. PMID: 23236279.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    257. Benhnia MR, Maybeno M, Blum D, Aguilar-Sino R, Matho M, Meng X, Head S, Felgner PL, Zajonc DM, Koriazova L, Kato S, Burton DR, Xiang Y, Crowe JE, Peters B, Crotty S. Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. J Virol. 2013 Feb; 87(3):1569-85. PMID: 23152530.
      Citations: 13     Fields:    Translation:HumansCells
    258. Hotard AL, Shaikh FY, Lee S, Yan D, Teng MN, Plemper RK, Crowe JE, Moore ML. A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis. Virology. 2012 Dec 05; 434(1):129-36. PMID: 23062737.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    259. Hayakawa M, Toda N, Carrillo N, Thornburg NJ, Crowe JE, Barbas CF. A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase. Chembiochem. 2012 Oct 15; 13(15):2191-5. PMID: 22965667.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    260. Briney BS, Willis JR, Hicar MD, Thomas JW, Crowe JE. Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire. Immunology. 2012 Sep; 137(1):56-64. PMID: 22612413.
      Citations: 34     Fields:    Translation:HumansCells
    261. Engelhardt BG, Sengsayadeth SM, Jagasia M, Savani BN, Kassim AA, Lu P, Shyr Y, Yoder SM, Rock MT, Crowe JE. Tissue-specific regulatory T cells: biomarker for acute graft-vs-host disease and survival. Exp Hematol. 2012 Dec; 40(12):974-982.e1. PMID: 22885125.
      Citations: 8     Fields:    Translation:HumansCells
    262. Crowe JE. Influenza virus resistance to human neutralizing antibodies. mBio. 2012; 3(4):e00213-12. PMID: 22851660.
      Citations: 1     Fields:    Translation:HumansCells
    263. Shaikh FY, Utley TJ, Craven RE, Rogers MC, Lapierre LA, Goldenring JR, Crowe JE. Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins. PLoS One. 2012; 7(7):e40826. PMID: 22808269.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    264. Lifland AW, Jung J, Alonas E, Zurla C, Crowe JE, Santangelo PJ. Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS. J Virol. 2012 Aug; 86(15):8245-58. PMID: 22623778.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    265. Briney BS, Willis JR, Crowe JE. Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes. PLoS One. 2012; 7(5):e36750. PMID: 22590602.
      Citations: 77     Fields:    Translation:HumansCellsCTClinical Trials
    266. de Alwis R, Smith SA, Olivarez NP, Messer WB, Huynh JP, Wahala WM, White LJ, Diamond MS, Baric RS, Crowe JE, de Silva AM. Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc Natl Acad Sci U S A. 2012 May 08; 109(19):7439-44. PMID: 22499787.
      Citations: 217     Fields:    Translation:HumansAnimalsCells
    267. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Albrecht R, Blum DL, Ramos I, Fernandez-Sesma A, Edwards KM, García-Sastre A, Basler CF, Crowe JE. Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. J Virol. 2012 Jun; 86(11):6334-40. PMID: 22457520.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    268. Wen X, Krause JC, Leser GP, Cox RG, Lamb RA, Williams JV, Crowe JE, Jardetzky TS. Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat Struct Mol Biol. 2012 Mar 04; 19(4):461-3. PMID: 22388735.
      Citations: 41     Fields:    Translation:HumansCells
    269. Shaikh FY, Cox RG, Lifland AW, Hotard AL, Williams JV, Moore ML, Santangelo PJ, Crowe JE. A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles. mBio. 2012; 3(1). PMID: 22318318.
      Citations: 31     Fields:    Translation:HumansCells
    270. Engelhardt BG, Jagasia SM, Crowe JE, Griffith ML, Savani BN, Kassim AA, Lu P, Weitkamp JH, Moore DJ, Yoder SM, Rock MT, Jagasia M. Predicting posttransplantation diabetes mellitus by regulatory T-cell phenotype: implications for metabolic intervention to modulate alloreactivity. Blood. 2012 Mar 08; 119(10):2417-21. PMID: 22262764.
      Citations: 9     Fields:    Translation:HumansCells
    271. Dochow M, Krumm SA, Crowe JE, Moore ML, Plemper RK. Independent structural domains in paramyxovirus polymerase protein. J Biol Chem. 2012 Feb 24; 287(9):6878-91. PMID: 22215662.
      Citations: 33     Fields:    Translation:AnimalsCells
    272. Smith SA, Zhou Y, Olivarez NP, Broadwater AH, de Silva AM, Crowe JE. Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection. J Virol. 2012 Mar; 86(5):2665-75. PMID: 22171265.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    273. Zhang GL, Ansari HR, Bradley P, Cawley GC, Hertz T, Hu X, Jojic N, Kim Y, Kohlbacher O, Lund O, Lundegaard C, Magaret CA, Nielsen M, Papadopoulos H, Raghava GP, Tal VS, Xue LC, Yanover C, Zhu S, Rock MT, Crowe JE, Panayiotou C, Polycarpou MM, Duch W, Brusic V. Machine learning competition in immunology - Prediction of HLA class I binding peptides. J Immunol Methods. 2011 Nov 30; 374(1-2):1-4. PMID: 21986107.
      Citations: 32     Fields:    Translation:HumansCells
    274. Joyner AS, Willis JR, Crowe JE, Aiken C. Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathog. 2011 Sep; 7(9):e1002234. PMID: 21931551.
      Citations: 30     Fields:    Translation:HumansCells
    275. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE. Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. J Immunol. 2011 Oct 01; 187(7):3704-11. PMID: 21880983.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    276. Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE. A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. J Virol. 2011 Oct; 85(20):10905-8. PMID: 21849447.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    277. Rock MT, McKinney BA, Yoder SM, Prudom CE, Wright DW, Crowe JE. Identification of potential human respiratory syncytial virus and metapneumovirus T cell epitopes using computational prediction and MHC binding assays. J Immunol Methods. 2011 Nov 30; 374(1-2):13-7. PMID: 21854782.
      Citations: 10     Fields:    Translation:HumansCells
    278. Lindquist ME, Mainou BA, Dermody TS, Crowe JE. Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication. Virology. 2011 Apr 25; 413(1):103-10. PMID: 21377708.
      Citations: 42     Fields:    Translation:HumansCells
    279. Schlesinger AE, Crowe JE. Sagittal orientation of ingested coins in the esophagus in children. AJR Am J Roentgenol. 2011 Mar; 196(3):670-2. PMID: 21343512.
      Citations: 5     Fields:    Translation:Humans
    280. Krause JC, Ekiert DC, Tumpey TM, Smith PB, Wilson IA, Crowe JE. An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody. mBio. 2011; 2(1):e00345-10. PMID: 21304166.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    281. Pishchany G, McCoy AL, Torres VJ, Krause JC, Crowe JE, Fabry ME, Skaar EP. Specificity for human hemoglobin enhances Staphylococcus aureus infection. Cell Host Microbe. 2010 Dec 16; 8(6):544-50. PMID: 21147468.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    282. Monsalvo AC, Batalle JP, Lopez MF, Krause JC, Klemenc J, Hernandez JZ, Maskin B, Bugna J, Rubinstein C, Aguilar L, Dalurzo L, Libster R, Savy V, Baumeister E, Aguilar L, Cabral G, Font J, Solari L, Weller KP, Johnson J, Echavarria M, Edwards KM, Chappell JD, Crowe JE, Williams JV, Melendi GA, Polack FP. Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nat Med. 2011 Feb; 17(2):195-9. PMID: 21131958.
      Citations: 128     Fields:    Translation:HumansCells
    283. Thornburg NJ, Shepherd B, Crowe JE. Transforming growth factor beta is a major regulator of human neonatal immune responses following respiratory syncytial virus infection. J Virol. 2010 Dec; 84(24):12895-902. PMID: 20926560.
      Citations: 26     Fields:    Translation:HumansCells
    284. Lindquist ME, Lifland AW, Utley TJ, Santangelo PJ, Crowe JE. Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. J Virol. 2010 Dec; 84(23):12274-84. PMID: 20844027.
      Citations: 92     Fields:    Translation:HumansCells
    285. Hicar MD, Chen X, Briney B, Hammonds J, Wang JJ, Kalams S, Spearman PW, Crowe JE. Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV. J Acquir Immune Defic Syndr. 2010 Jul; 54(3):223-35. PMID: 20531016.
      Citations: 26     Fields:    Translation:HumansCells
    286. Williams JV, Edwards KM, Weinberg GA, Griffin MR, Hall CB, Zhu Y, Szilagyi PG, Wang CK, Yang CF, Silva D, Ye D, Spaete RR, Crowe JE. Population-based incidence of human metapneumovirus infection among hospitalized children. J Infect Dis. 2010 Jun 15; 201(12):1890-8. PMID: 20446850.
      Citations: 51     Fields:    Translation:HumansCells
    287. Hicar MD, Kalams SA, Spearman PW, Crowe JE. Emerging studies of human HIV-specific antibody repertoires. Vaccine. 2010 May 26; 28 Suppl 2:B18-23. PMID: 20510738.
      Citations: 7     Fields:    Translation:HumansCells
    288. Xu R, Ekiert DC, Krause JC, Hai R, Crowe JE, Wilson IA. Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science. 2010 Apr 16; 328(5976):357-60. PMID: 20339031.
      Citations: 328     Fields:    Translation:HumansCellsPHPublic Health
    289. Engelhardt BG, Crowe JE. Homing in on acute graft vs. host disease: tissue-specific T regulatory and Th17 cells. Curr Top Microbiol Immunol. 2010; 341:121-46. PMID: 20563712.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    290. Crowe JE. Recent advances in the study of human antibody responses to influenza virus using optimized human hybridoma approaches. Vaccine. 2009 Dec 30; 27 Suppl 6:G47-51. PMID: 20006140.
      Citations: 9     Fields:    Translation:HumansCells
    291. Krause JC, Tumpey TM, Huffman CJ, McGraw PA, Pearce MB, Tsibane T, Hai R, Basler CF, Crowe JE. Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. J Virol. 2010 Mar; 84(6):3127-30. PMID: 20042511.
      Citations: 56     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    292. Williams JV, Weitkamp JH, Blum DL, LaFleur BJ, Crowe JE. The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations. Mol Immunol. 2009 Dec; 47(2-3):407-14. PMID: 19804909.
      Citations: 21     Fields:    Translation:HumansCells
    293. Yang CF, Wang CK, Tollefson SJ, Piyaratna R, Lintao LD, Chu M, Liem A, Mark M, Spaete RR, Crowe JE, Williams JV. Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years. Virol J. 2009 Sep 09; 6:138. PMID: 19740442.
      Citations: 40     Fields:    Translation:HumansCells
    294. Talbot HK, Shepherd BE, Crowe JE, Griffin MR, Edwards KM, Podsiad AB, Tollefson SJ, Wright PF, Williams JV. The pediatric burden of human coronaviruses evaluated for twenty years. Pediatr Infect Dis J. 2009 Aug; 28(8):682-7. PMID: 19633513.
      Citations: 42     Fields:    Translation:HumansCells
    295. Talbot HK, Crowe JE, Edwards KM, Griffin MR, Zhu Y, Weinberg GA, Szilagyi PG, Hall CB, Podsiad AB, Iwane M, Williams JV. Coronavirus infection and hospitalizations for acute respiratory illness in young children. J Med Virol. 2009 May; 81(5):853-6. PMID: 19319948.
      Citations: 35     Fields:    Translation:HumansCellsPHPublic Health
    296. Santangelo PJ, Lifland AW, Curt P, Sasaki Y, Bassell GJ, Lindquist ME, Crowe JE. Single molecule-sensitive probes for imaging RNA in live cells. Nat Methods. 2009 May; 6(5):347-9. PMID: 19349979.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    297. McKinney BA, Crowe JE, Guo J, Tian D. Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis. PLoS Genet. 2009 Mar; 5(3):e1000432. PMID: 19300503.
      Citations: 53     Fields:    Translation:Humans
    298. Moore ML, Chi MH, Luongo C, Lukacs NW, Polosukhin VV, Huckabee MM, Newcomb DC, Buchholz UJ, Crowe JE, Goleniewska K, Williams JV, Collins PL, Peebles RS. A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction. J Virol. 2009 May; 83(9):4185-94. PMID: 19211758.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    299. Nam KT, Lee HJ, Mok H, Romero-Gallo J, Crowe JE, Peek RM, Goldenring JR. Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. Gastroenterology. 2009 Apr; 136(4):1288-96. PMID: 19230855.
      Citations: 36     Fields:    Translation:Animals
    300. Derdowski A, Peters TR, Glover N, Qian R, Utley TJ, Burnett A, Williams JV, Spearman P, Crowe JE. Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation. J Gen Virol. 2008 Nov; 89(Pt 11):2698-2708. PMID: 18931065.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    301. Mok H, Tollefson SJ, Podsiad AB, Shepherd BE, Polosukhin VV, Johnston RE, Williams JV, Crowe JE. An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats. J Virol. 2008 Nov; 82(22):11410-8. PMID: 18786987.
      Citations: 26     Fields:    Translation:AnimalsCells
    302. Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, Crowe JE. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 2008 Sep 25; 455(7212):532-6. PMID: 18716625.
      Citations: 183     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    303. Mok H, Lee S, Wright DW, Crowe JE. Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope. Vaccine. 2008 Sep 02; 26(37):4775-82. PMID: 18662734.
      Citations: 9     Fields:    Translation:AnimalsCells
    304. Utley TJ, Ducharme NA, Varthakavi V, Shepherd BE, Santangelo PJ, Lindquist ME, Goldenring JR, Crowe JE. Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2. Proc Natl Acad Sci U S A. 2008 Jul 22; 105(29):10209-14. PMID: 18621683.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    305. Reif DM, McKinney BA, Motsinger AA, Chanock SJ, Edwards KM, Rock MT, Moore JH, Crowe JE. Genetic basis for adverse events after smallpox vaccination. J Infect Dis. 2008 Jul 01; 198(1):16-22. PMID: 18454680.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    306. Yu X, McGraw PA, House FS, Crowe JE. An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies. J Immunol Methods. 2008 Jul 31; 336(2):142-51. PMID: 18514220.
      Citations: 68     Fields:    Translation:HumansCells
    307. Kallewaard NL, McKinney BA, Gu Y, Chen A, Prasad BV, Crowe JE. Functional maturation of the human antibody response to rotavirus. J Immunol. 2008 Mar 15; 180(6):3980-9. PMID: 18322207.
      Citations: 19     Fields:    Translation:HumansCells
    308. Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE. Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones. J Immunol. 2008 Mar 01; 180(5):3279-88. PMID: 18292552.
      Citations: 30     Fields:    Translation:HumansCells
    309. Mok H, Lee S, Utley TJ, Shepherd BE, Polosukhin VV, Collier ML, Davis NL, Johnston RE, Crowe JE. Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats. J Virol. 2007 Dec; 81(24):13710-22. PMID: 17928349.
      Citations: 43     Fields:    Translation:AnimalsCellsPHPublic Health
    310. McKinney BA, Kallewaard NL, Crowe JE, Meiler J. Using the natural evolution of a rotavirus-specific human monoclonal antibody to predict the complex topography of a viral antigenic site. Immunome Res. 2007 Sep 18; 3:8. PMID: 17877819.
      Citations: 9     
    311. Crowe JE. Genetic predisposition for adverse events after vaccination. J Infect Dis. 2007 Jul 15; 196(2):176-7. PMID: 17570102.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    312. Williams JV, Chen Z, Cseke G, Wright DW, Keefer CJ, Tollefson SJ, Hessell A, Podsiad A, Shepherd BE, Sanna PP, Burton DR, Crowe JE, Williamson RA. A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo. J Virol. 2007 Aug; 81(15):8315-24. PMID: 17522220.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    313. Greenbaum JA, Andersen PH, Blythe M, Bui HH, Cachau RE, Crowe J, Davies M, Kolaskar AS, Lund O, Morrison S, Mumey B, Ofran Y, Pellequer JL, Pinilla C, Ponomarenko JV, Raghava GP, van Regenmortel MH, Roggen EL, Sette A, Schlessinger A, Sollner J, Zand M, Peters B. Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools. J Mol Recognit. 2007 Mar-Apr; 20(2):75-82. PMID: 17205610.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    314. Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE. Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells. Mol Immunol. 2007 Mar; 44(9):2173-83. PMID: 17196657.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    315. Lee S, Miller SA, Wright DW, Rock MT, Crowe JE. Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection. J Virol. 2007 Mar; 81(5):2349-58. PMID: 17182672.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    316. Cseke G, Wright DW, Tollefson SJ, Johnson JE, Crowe JE, Williams JV. Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J Virol. 2007 Jan; 81(2):698-707. PMID: 17050599.
      Citations: 37     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    317. Miller SA, Tollefson S, Crowe JE, Williams JV, Wright DW. Examination of a fusogenic hexameric core from human metapneumovirus and identification of a potent synthetic peptide inhibitor from the heptad repeat 1 region. J Virol. 2007 Jan; 81(1):141-9. PMID: 17035305.
      Citations: 17     Fields:    Translation:Cells
    318. McKinney BA, Reif DM, Rock MT, Edwards KM, Kingsmore SF, Moore JH, Crowe JE. Cytokine expression patterns associated with systemic adverse events following smallpox immunization. J Infect Dis. 2006 Aug 15; 194(4):444-53. PMID: 16845627.
      Citations: 24     Fields:    Translation:HumansCells
    319. Rock MT, Yoder SM, Talbot TR, Edwards KM, Crowe JE. Cellular immune responses to diluted and undiluted aventis pasteur smallpox vaccine. J Infect Dis. 2006 Aug 15; 194(4):435-43. PMID: 16845626.
      Citations: 11     Fields:    Translation:HumansCells
    320. Tian C, Kron GK, Dischert KM, Higginbotham JN, Crowe JE. Low expression of the interleukin (IL)-4 receptor alpha chain and reduced signalling via the IL-4 receptor complex in human neonatal B cells. Immunology. 2006 Sep; 119(1):54-62. PMID: 16764687.
      Citations: 10     Fields:    Translation:HumansCells
    321. Weitkamp JH, Lafleur BJ, Crowe JE. Rotavirus-specific CD5+ B cells in young children exhibit a distinct antibody repertoire compared with CD5- B cells. Hum Immunol. 2006 Jan-Feb; 67(1-2):33-42. PMID: 16698423.
      Citations: 9     Fields:    Translation:HumansCells
    322. Bowen AL, Tian C, LaFleur BJ, Crowe JE. Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth. Hum Immunol. 2006 Jan-Feb; 67(1-2):43-6. PMID: 16698424.
      Citations: 4     Fields:    Translation:HumansCells
    323. Williams JV, Wang CK, Yang CF, Tollefson SJ, House FS, Heck JM, Chu M, Brown JB, Lintao LD, Quinto JD, Chu D, Spaete RR, Edwards KM, Wright PF, Crowe JE. The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience. J Infect Dis. 2006 Feb 01; 193(3):387-95. PMID: 16388486.
      Citations: 106     Fields:    Translation:HumansCellsPHPublic Health
    324. Martino R, Porras RP, Rabella N, Williams JV, Rámila E, Margall N, Labeaga R, Crowe JE, Coll P, Sierra J. Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies. Biol Blood Marrow Transplant. 2005 Oct; 11(10):781-96. PMID: 16182179.
      Citations: 87     Fields:    Translation:HumansCellsPHPublic Health
    325. Brock SC, Heck JM, McGraw PA, Crowe JE. The transmembrane domain of the respiratory syncytial virus F protein is an orientation-independent apical plasma membrane sorting sequence. J Virol. 2005 Oct; 79(19):12528-35. PMID: 16160180.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    326. Williams JV, Tollefson SJ, Johnson JE, Crowe JE. The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol. 2005 Sep; 79(17):10944-51. PMID: 16103146.
      Citations: 59     Fields:    Translation:AnimalsCells
    327. Williams JV, Crowe JE, Enriquez R, Minton P, Peebles RS, Hamilton RG, Higgins S, Griffin M, Hartert TV. Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults. J Infect Dis. 2005 Oct 01; 192(7):1149-53. PMID: 16136455.
      Citations: 66     Fields:    Translation:HumansCells
    328. Williams JV, Martino R, Rabella N, Otegui M, Parody R, Heck JM, Crowe JE. A prospective study comparing human metapneumovirus with other respiratory viruses in adults with hematologic malignancies and respiratory tract infections. J Infect Dis. 2005 Sep 15; 192(6):1061-5. PMID: 16107960.
      Citations: 80     Fields:    Translation:HumansCells
    329. Rutigliano JA, Rock MT, Johnson AK, Crowe JE, Graham BS. Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus. Virology. 2005 Jul 05; 337(2):335-43. PMID: 15916793.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    330. Weitkamp JH, Lafleur BJ, Greenberg HB, Crowe JE. Natural evolution of a human virus-specific antibody gene repertoire by somatic hypermutation requires both hotspot-directed and randomly-directed processes. Hum Immunol. 2005 Jun; 66(6):666-76. PMID: 15993712.
      Citations: 17     Fields:    Translation:HumansCells
    331. Williams JV, Tollefson SJ, Heymann PW, Carper HT, Patrie J, Crowe JE. Human metapneumovirus infection in children hospitalized for wheezing. J Allergy Clin Immunol. 2005 Jun; 115(6):1311-2. PMID: 15940152.
      Citations: 38     Fields:    Translation:HumansCells
    332. Chen X, Rock MT, Hammonds J, Tartaglia J, Shintani A, Currier J, Slike B, Crowe JE, Marovich M, Spearman P. Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses. J Virol. 2005 May; 79(9):5537-47. PMID: 15827168.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    333. Bentzen EL, House F, Utley TJ, Crowe JE, Wright DW. Progression of respiratory syncytial virus infection monitored by fluorescent quantum dot probes. Nano Lett. 2005 Apr; 5(4):591-5. PMID: 15826092.
      Citations: 26     Fields:    Translation:HumansCells
    334. Rock MT, Yoder SM, Wright PF, Talbot TR, Edwards KM, Crowe JE. Differential regulation of granzyme and perforin in effector and memory T cells following smallpox immunization. J Immunol. 2005 Mar 15; 174(6):3757-64. PMID: 15749916.
      Citations: 25     Fields:    Translation:HumansCells
    335. Weitkamp JH, Kallewaard NL, Bowen AL, Lafleur BJ, Greenberg HB, Crowe JE. VH1-46 is the dominant immunoglobulin heavy chain gene segment in rotavirus-specific memory B cells expressing the intestinal homing receptor alpha4beta7. J Immunol. 2005 Mar 15; 174(6):3454-60. PMID: 15749880.
      Citations: 25     Fields:    Translation:HumansCells
    336. Tai JH, Williams JV, Edwards KM, Wright PF, Crowe JE, Dermody TS. Prevalence of reovirus-specific antibodies in young children in Nashville, Tennessee. J Infect Dis. 2005 Apr 15; 191(8):1221-4. PMID: 15776366.
      Citations: 58     Fields:    Translation:HumansCells
    337. Shaklee JF, Talbot TR, Muldowney JA, Vaughan DE, Butler J, House F, Crowe JE, Smith LH, Edwards KM. Smallpox vaccination does not elevate systemic levels of prothrombotic proteins associated with ischemic cardiac events. J Infect Dis. 2005 Mar 01; 191(5):724-30. PMID: 15688286.
      Citations: 2     Fields:    Translation:Humans
    338. Kallewaard NL, Bowen AL, Crowe JE. Cooperativity of actin and microtubule elements during replication of respiratory syncytial virus. Virology. 2005 Jan 05; 331(1):73-81. PMID: 15582654.
      Citations: 54     Fields:    Translation:HumansCells
    339. Crowe JE. Human metapneumovirus as a major cause of human respiratory tract disease. Pediatr Infect Dis J. 2004 Nov; 23(11 Suppl):S215-21. PMID: 15577576.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    340. Talbot TR, Stapleton JT, Brady RC, Winokur PL, Bernstein DI, Germanson T, Yoder SM, Rock MT, Crowe JE, Edwards KM. Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial. JAMA. 2004 Sep 08; 292(10):1205-12. PMID: 15353533.
      Citations: 15     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    341. Rock MT, Yoder SM, Talbot TR, Edwards KM, Crowe JE. Adverse events after smallpox immunizations are associated with alterations in systemic cytokine levels. J Infect Dis. 2004 Apr 15; 189(8):1401-10. PMID: 15073677.
      Citations: 25     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    342. Suara RO, Crowe JE. Effect of zinc salts on respiratory syncytial virus replication. Antimicrob Agents Chemother. 2004 Mar; 48(3):783-90. PMID: 14982765.
      Citations: 51     Fields:    Translation:HumansCells
    343. Williams JV, Harris PA, Tollefson SJ, Halburnt-Rush LL, Pingsterhaus JM, Edwards KM, Wright PF, Crowe JE. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med. 2004 Jan 29; 350(5):443-50. PMID: 14749452.
      Citations: 364     Fields:    Translation:HumansCells
    344. Brock SC, Goldenring JR, Crowe JE. Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15143-8. PMID: 14630951.
      Citations: 61     Fields:    Translation:AnimalsCells
    345. Weitkamp JH, Kallewaard N, Kusuhara K, Bures E, Williams JV, LaFleur B, Greenberg HB, Crowe JE. Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol. 2003 Nov 01; 171(9):4680-8. PMID: 14568943.
      Citations: 32     Fields:    Translation:HumansCells
    346. Halasa NB, Whitlock JA, McCurley TL, Smith JA, Zhu Q, Ochs H, Dermody TS, Crowe JE. Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein. Clin Infect Dis. 2003 Nov 15; 37(10):e136-41. PMID: 14583885.
      Citations: 4     Fields:    Translation:HumansCells
    347. Venter M, Rock M, Puren AJ, Tiemessen CT, Crowe JE. Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains. J Virol. 2003 Jul; 77(13):7319-29. PMID: 12805430.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    348. Crowe JE, Williams JV. Immunology of viral respiratory tract infection in infancy. Paediatr Respir Rev. 2003 Jun; 4(2):112-9. PMID: 12758048.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    349. Crowe JE, Sannella EC, Pfeiffer S, Zorn GL, Azimzadeh A, Newman R, Miller GG, Pierson RN. CD154 regulates primate humoral immunity to influenza. Am J Transplant. 2003 Jun; 3(6):680-8. PMID: 12780559.
      Citations: 6     Fields:    Translation:Animals
    350. Weitkamp JH, Kallewaard N, Kusuhara K, Feigelstock D, Feng N, Greenberg HB, Crowe JE. Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J Immunol Methods. 2003 Apr 01; 275(1-2):223-37. PMID: 12667686.
      Citations: 30     Fields:    Translation:HumansCells
    351. Rock MT, Crowe JE. Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein. Immunology. 2003 Apr; 108(4):474-80. PMID: 12667209.
      Citations: 25     Fields:    Translation:HumansCells
    352. Brock SC, McGraw PA, Wright PF, Crowe JE. The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun. 2002 Sep; 70(9):5091-5. PMID: 12183558.
      Citations: 14     Fields:    Translation:HumansCells
    353. Peters TR, Jennings MT, Crowe JE. Pneumocystis carinii pneumonia in a girl with a midbrain glioma. Pediatr Hematol Oncol. 2002 Mar; 19(2):141-3. PMID: 11881789.
      Citations:    Fields:    Translation:Humans
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