 PETER HOTEZ
| Title | Professor |
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| Institution | Baylor College of Medicine |
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| Department | Department of Pediatrics |
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| Division | Pediatrics-Tropical Medicine |
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| Title | Professor |
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| Institution | Baylor College of Medicine |
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| Department | Department of Molecular Virology & Microbiology |
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| Division | Molecular Virology & Microbiology |
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| Title | Dean |
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| Institution | Baylor College of Medicine |
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| Department | National School of Tropical Medicine |
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| Division | National School Tropical Medicine |
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 ORNG Applications Research R29AI032726 (HOTEZ, PETER J)Dec 1, 1992 - Nov 30, 1999 NIH/NIAID
HOOKWORM LARVAL INFECTIVITY AND DEVELOPMENT
Role: Principal Investigator |
| R01AI032726 (HOTEZ, PETER J)Dec 1, 1992 - Jul 31, 2000 NIH/NIAID
HOOKWORM LARVAL INFECTIVITY AND DEVELOPMENT
Role: Principal Investigator |
| R41AI040447 (HOTEZ, PETER J)Sep 30, 1996 - Sep 29, 1998 NIH/NIAID
RECOMBINANT HOOKWORM (NEMATODE) VACCINE
Role: Principal Investigator |
| R56AI090577 (HOTEZ, PETER J)Jan 1, 2011 - Sep 30, 2013 NIH/NIAID
PRODUCT DEVELOPMENT OF A MEMBRANE TETRASPANIN VACCINE AGAINST SCHISTOSOMIASIS
Role: Principal Investigator |
| R01AI098775 (HOTEZ, PETER J)May 4, 2012 - Apr 30, 2017 NIH/NIAID
RBD recombinant protein-based SARS vaccine for biodefense
Role: Principal Investigator |
| R21AI144555 (HOTEZ, PETER J)Feb 19, 2019 - Jan 31, 2021 NIH/NIAID
A novel mucosal trichuriasis vaccine for Th2 immune protection.
Role: Principal Investigator |
| R56AI140872 (HOTEZ, PETER J)Mar 11, 2020 - Feb 28, 2021 NIH/NIAID
Development of a safe and effective RBD-based vaccine against MERS-CoV
Role: Principal Investigator |
Bibliographic
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Hotez PJ, Bush K, Oswald A, Rockman G, Lim IT, Jee Y, Moon CJ, Kim JH, Kim Y. A new Korean Research Investment for Global Health Technology (RIGHT) Fund to advance innovative neglected-disease technologies. PLoS Negl Trop Dis. 2020 Sep; 14(9):e0007956. PMID: 32881862.
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Hotez PJ, Harrison W, Fenwick A, Bustinduy AL, Ducker C, Mbabazi PS, Engels D, Kjetland EF. Correction: Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women. PLoS Negl Trop Dis. 2020 Sep; 14(9):e0008725. PMID: 32870910.
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Ness TE, Agrawal V, Bedard K, Ouellette L, Erickson TA, Hotez P, Weatherhead JE. Maternal Hookworm Infection and Its Effects on Maternal Health: A Systematic Review and Meta-Analysis. Am J Trop Med Hyg. 2020 Aug 24. PMID: 32840198.
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Mejia R, Hotez P, Bottazzi ME. Global COVID-19 Efforts as the Platform to Achieving the Sustainable Development Goals. Curr Trop Med Rep. 2020 Aug 20; 1-5. PMID: 32844081.
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Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, Li G, Peng J, Correa-Oliveira R, Hotez P, Bethony J. Correction: Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. PLoS Negl Trop Dis. 2020 08; 14(8):e0008670. PMID: 32804987.
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Chadalawada S, Sillau S, Archuleta S, Mundo W, Bandali M, Parra-Henao G, Rodriguez-Morales AJ, Villamil-Gomez WE, Suárez JA, Shapiro L, Hotez PJ, Woc-Colburn L, DeSanto K, Rassi A, Franco-Paredes C, Henao-Martínez AF. Risk of Chronic Cardiomyopathy Among Patients With the Acute Phase or Indeterminate Form of Chagas Disease: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020 Aug 03; 3(8):e2015072. PMID: 32865573.
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Hotez PJ, Bottazzi ME. Developing a low-cost and accessible COVID-19 vaccine for global health. PLoS Negl Trop Dis. 2020 07; 14(7):e0008548. PMID: 32726304.
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Hotez P. COVID19 in America: an October plan. Microbes Infect. 2020 Jul 23. PMID: 32712199.
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Bartsch SM, O'Shea KJ, Ferguson MC, Bottazzi ME, Wedlock PT, Strych U, McKinnell JA, Siegmund SS, Cox SN, Hotez PJ, Lee BY. Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention. Am J Prev Med. 2020 Jul 15. PMID: 32778354.
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Hotez PJ, Corry DB, Strych U, Bottazzi ME. COVID-19 vaccines: neutralizing antibodies and the alum advantage. Nat Rev Immunol. 2020 07; 20(7):399-400. PMID: 32499636.
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Bottazzi ME, Strych U, Hotez PJ, Corry DB. Coronavirus vaccine-associated lung immunopathology-what is the significance? Microbes Infect. 2020 Jun 26. PMID: 32599077.
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Villanueva-Lizama LE, Cruz-Chan JV, Versteeg L, Teh-Poot CF, Hoffman K, Kendricks A, Keegan B, Pollet J, Gusovsky F, Hotez PJ, Bottazzi ME, Jones KM. TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens. Parasite Immunol. 2020 Jun 26; e12769. PMID: 32592180.
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Franco-Paredes C, Jankousky K, Schultz J, Bernfeld J, Cullen K, Quan NG, Kon S, Hotez P, Henao-Martínez AF, Krsak M. COVID-19 in jails and prisons: A neglected infection in a marginalized population. PLoS Negl Trop Dis. 2020 06; 14(6):e0008409. PMID: 32569274.
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Singer R, Xu TH, Herrera LNS, Villar MJ, Faust KM, Hotez PJ, Aiken ARA, Mejia R. Prevalence of Intestinal Parasites in a Low-Income Texas Community. Am J Trop Med Hyg. 2020 06; 102(6):1386-1395. PMID: 32207401.
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Bartsch SM, O'Shea KJ, Ferguson MC, Bottazzi ME, Cox SN, Strych U, McKinnell JA, Wedlock PT, Siegmund SS, Hotez PJ, Lee BY. How Efficacious Must a COVID-19 Coronavirus Vaccine be to Prevent or Stop an Epidemic by Itself. medRxiv. 2020 May 30. PMID: 32511569.
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Chen WH, Tao X, Agrawal A, Algaissi A, Peng BH, Pollet J, Strych U, Bottazzi ME, Hotez PJ, Lustigman S, Du L, Jiang S, Tseng CK. Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Alum Induces Protective Immunity and Reduces Immune Enhancement. bioRxiv. 2020 May 22. PMID: 32511385.
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Hotez PJ. COVID19 meets the antivaccine movement. Microbes Infect. 2020 May - Jun; 22(4-5):162-164. PMID: 32442682.
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Dumonteil E, Herrera C, Tu W, Goff K, Fahlberg M, Haupt E, Kaur A, Marx PA, Ortega-Lopez J, Hotez PJ, Bottazzi ME. Safety and immunogenicity of a recombinant vaccine against Trypanosoma cruzi in Rhesus macaques. Vaccine. 2020 Jun 15; 38(29):4584-4591. PMID: 32417142.
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Tyungu DL, McCormick D, Lau CL, Chang M, Murphy JR, Hotez PJ, Mejia R, Pollack H. Toxocara species environmental contamination of public spaces in New York City. PLoS Negl Trop Dis. 2020 05; 14(5):e0008249. PMID: 32369482.
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Hotez PJ, Corry DB, Bottazzi ME. COVID-19 vaccine design: the Janus face of immune enhancement. Nat Rev Immunol. 2020 06; 20(6):347-348. PMID: 32346094.
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Ma G, Rostami A, Wang T, Hofmann A, Hotez PJ, Gasser RB. Global and regional seroprevalence estimates for human toxocariasis: A call for action. Adv Parasitol. 2020; 109:275-290. PMID: 32381202.
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Rostami A, Sepidarkish M, Ma G, Wang T, Ebrahimi M, Fakhri Y, Mirjalali H, Hofmann A, Macpherson CNL, Hotez PJ, Gasser RB. Global prevalence of Toxocara infection in cats. Adv Parasitol. 2020; 109:615-639. PMID: 32381220.
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Hotez PJ, Bottazzi ME, Corry DB. The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement. Microbes Infect. 2020 May - Jun; 22(4-5):165-167. PMID: 32305501.
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Chen WH, Hotez PJ, Bottazzi ME. Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19. Hum Vaccin Immunother. 2020 06 02; 16(6):1239-1242. PMID: 32298218.
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Hotez PJ, Bottazzi ME, Singh SK, Brindley PJ, Kamhawi S. Will COVID-19 become the next neglected tropical disease? PLoS Negl Trop Dis. 2020 04; 14(4):e0008271. PMID: 32275667.
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Hotez PJ. Toxocariasis: A neglected infection for the Anthropocene epoch. Adv Parasitol. 2020; 109:879-883. PMID: 32381232.
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Hotez PJ. Combating antiscience: Are we preparing for the 2020s? PLoS Biol. 2020 03; 18(3):e3000683. PMID: 32218568.
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Hotez PJ, Damania A, Bottazzi ME. Central Latin America: Two decades of challenges in neglected tropical disease control. PLoS Negl Trop Dis. 2020 03; 14(3):e0007962. PMID: 32214311.
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Kendricks AL, Gray SB, Wilkerson GK, Sands CM, Abee CR, Bernacky BJ, Hotez PJ, Bottazzi ME, Craig SL, Jones KM. Reproductive Outcomes in Rhesus Macaques (Macaca mulatta) with Naturally-acquired Trypanosoma cruzi Infection. Comp Med. 2020 04 01; 70(2):152-159. PMID: 32183928.
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Bartsch SM, Stokes-Cawley OJ, Buekens P, Asti L, Bottazzi ME, Strych U, Wedlock PT, Mitgang EA, Meymandi S, Falcon-Lezama JA, Hotez PJ, Lee BY. The potential economic value of a therapeutic Chagas disease vaccine for pregnant women to prevent congenital transmission. Vaccine. 2020 Apr 03; 38(16):3261-3270. PMID: 32171575.
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Chen WH, Strych U, Hotez PJ, Bottazzi ME. The SARS-CoV-2 Vaccine Pipeline: an Overview. Curr Trop Med Rep. 2020 Mar 03; 1-4. PMID: 32219057.
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Hotez PJ, Booker C. STOP: Study, Treat, Observe, and Prevent Neglected Diseases of Poverty Act. PLoS Negl Trop Dis. 2020 02; 14(2):e0008064. PMID: 32106246.
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Hotez PJ, Nuzhath T, Colwell B. Combating vaccine hesitancy and other 21st century social determinants in the global fight against measles. Curr Opin Virol. 2020 Apr; 41:1-7. PMID: 32113136.
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Rostami A, Riahi SM, Hofmann A, Ma G, Wang T, Behniafar H, Taghipour A, Fakhri Y, Spotin A, Chang BCH, Macpherson CNL, Hotez PJ, Gasser RB. Global prevalence of Toxocara infection in dogs. Adv Parasitol. 2020; 109:561-583. PMID: 32381218.
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Chen WH, Nyon MP, Poongavanam MV, Liu Z, Biter AB, Kundu RT, Strych U, Hotez PJ, Bottazzi ME. Process Characterization and Biophysical Analysis for a Yeast-Expressed Phlebotomus papatasi Salivary Protein (PpSP15) as a Leishmania Vaccine Candidate. J Pharm Sci. 2020 05; 109(5):1673-1680. PMID: 32070701.
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Versteeg L, Wei J, Liu Z, Keegan B, Fujiwara RT, Jones KM, Asojo O, Strych U, Bottazzi ME, Hotez PJ, Zhan B. Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection. PLoS Negl Trop Dis. 2020 02; 14(2):e0008057. PMID: 32053593.
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Hotez PJ, Aksoy S, Brindley PJ, Kamhawi S. What constitutes a neglected tropical disease? PLoS Negl Trop Dis. 2020 01; 14(1):e0008001. PMID: 31999732.
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Hotez PJ, Aksoy S, Brindley PJ, Kamhawi S. World neglected tropical diseases day. PLoS Negl Trop Dis. 2020 01; 14(1):e0007999. PMID: 31995572.
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Bartsch SM, Asti L, Stokes-Cawley OJ, Sim SY, Bottazzi ME, Hotez PJ, Lee BY. The Potential Economic Value of a Zika Vaccine for a Woman of Childbearing Age. Am J Prev Med. 2020 03; 58(3):370-377. PMID: 31980305.
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Hotez PJ, Engels D, Gyapong M, Ducker C, Malecela MN. Female Genital Schistosomiasis. N Engl J Med. 2019 Dec 26; 381(26):2493-2495. PMID: 31881137.
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Nyathi S, Karpel HC, Sainani KL, Maldonado Y, Hotez PJ, Bendavid E, Lo NC. The 2016 California policy to eliminate nonmedical vaccine exemptions and changes in vaccine coverage: An empirical policy analysis. PLoS Med. 2019 12; 16(12):e1002994. PMID: 31869328.
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Rostami A, Riahi SM, Holland CV, Taghipour A, Khalili-Fomeshi M, Fakhri Y, Omrani VF, Hotez PJ, Gasser RB. Seroprevalence estimates for toxocariasis in people worldwide: A systematic review and meta-analysis. PLoS Negl Trop Dis. 2019 12; 13(12):e0007809. PMID: 31856156.
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Hoffman KA, Reynolds C, Bottazzi ME, Hotez P, Jones K. Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. J Am Heart Assoc. 2019 11 19; 8(22):e013365. PMID: 31718442.
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Gostin LO, Hodge JG, Bloom BR, El-Mohandes A, Fielding J, Hotez P, Kurth A, Larson HJ, Orenstein WA, Rabin K, Ratzan SC, Salmon D. The public health crisis of underimmunisation: a global plan of action. Lancet Infect Dis. 2020 01; 20(1):e11-e16. PMID: 31706795.
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Hotez PJ. Whatever happened to China's neglected tropical diseases? Infect Dis Poverty. 2019 Oct 02; 8(1):85. PMID: 31578156.
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Biter AB, Pollet J, Chen WH, Strych U, Hotez PJ, Bottazzi ME. A method to probe protein structure from UV absorbance spectra. Anal Biochem. 2019 12 15; 587:113450. PMID: 31550438.
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Hotez PJ. The rise or fall of neglected tropical diseases in East Asia Pacific. Acta Trop. 2020 Feb; 202:105182. PMID: 31550453.
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Versteeg L, Almutairi MM, Hotez PJ, Pollet J. Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections. Vaccines (Basel). 2019 Sep 20; 7(4). PMID: 31547081.
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George PJ, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans. PLoS Negl Trop Dis. 2019 09; 13(9):e0007730. PMID: 31525197.
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Hotez PJ. Immunizations and vaccines: a decade of successes and reversals, and a call for 'vaccine diplomacy'. Int Health. 2019 09 02; 11(5):331-333. PMID: 31034023.
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Parra-Henao G, Oliveros H, Hotez PJ, Motoa G, Franco-Paredes C, Henao-Martínez AF. In Search of Congenital Chagas Disease in the Sierra Nevada de Santa Marta, Colombia. Am J Trop Med Hyg. 2019 09; 101(3):482-483. PMID: 31264558.
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Paniz-Mondolfi AE, Grillet ME, Tami A, Oliveira-Miranda MA, Noguera LD, Hotez P, Oletta JF. Venezuela's upheaval threatens Yanomami. Science. 2019 08 23; 365(6455):766-767. PMID: 31439788.
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Bartsch SM, Asti L, Cox SN, Durham DP, Randall S, Hotez PJ, Galvani AP, Lee BY. What Is the Value of Different Zika Vaccination Strategies to Prevent and Mitigate Zika Outbreaks? J Infect Dis. 2019 08 09; 220(6):920-931. PMID: 30544164.
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Hotez P. DR Congo and Nigeria: New neglected tropical disease threats and solutions for the bottom 40. PLoS Negl Trop Dis. 2019 08; 13(8):e0007145. PMID: 31393879.
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Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J. Response to `letter to the editor: 'Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America'´. Expert Rev Anti Infect Ther. 2019 09; 17(9):673-675. PMID: 31361163.
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Hotez PJ. Globalists versus nationalists: Bridging the divide through blue marble health. PLoS Negl Trop Dis. 2019 07; 13(7):e0007156. PMID: 31295247.
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Bottazzi ME, Hotez PJ. "Running the Gauntlet": Formidable challenges in advancing neglected tropical diseases vaccines from development through licensure, and a "Call to Action". Hum Vaccin Immunother. 2019; 15(10):2235-2242. PMID: 31180271.
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Ratzan SC, Bloom BR, El-Mohandes A, Fielding J, Gostin LO, Hodge JG, Hotez P, Kurth A, Larson HJ, Nurse J, Omer SB, Orenstein WA, Salmon D, Rabin K. The Salzburg Statement on Vaccination Acceptance. J Health Commun. 2019; 24(5):581-583. PMID: 31262227.
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Engelman D, Cantey PT, Marks M, Solomon AW, Chang AY, Chosidow O, Enbiale W, Engels D, Hay RJ, Hendrickx D, Hotez PJ, Kaldor JM, Kama M, Mackenzie CD, McCarthy JS, Martin DL, Mengistu B, Maurer T, Negussu N, Romani L, Sokana O, Whitfeld MJ, Fuller LC, Steer AC. The public health control of scabies: priorities for research and action. Lancet. 2019 Jul 06; 394(10192):81-92. PMID: 31178154.
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Hotez PJ. Science tikkun: A framework embracing the right of access to innovation and translational medicine on a global scale. PLoS Negl Trop Dis. 2019 06; 13(6):e0007117. PMID: 31170155.
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Barry MA, Versteeg L, Wang Q, Pollet J, Zhan B, Gusovsky F, Bottazzi ME, Hotez PJ, Jones KM. A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection. PLoS Negl Trop Dis. 2019 05; 13(5):e0007413. PMID: 31145733.
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Coelho CH, Rappuoli R, Hotez PJ, Duffy PE. Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction. Trends Parasitol. 2019 07; 35(7):483-486. PMID: 31153722.
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Bartsch SM, Bottazzi ME, Asti L, Strych U, Meymandi S, Falcón-Lezama JA, Randall S, Hotez PJ, Lee BY. Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients. Vaccine. 2019 06 19; 37(28):3704-3714. PMID: 31104883.
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Hotez PJ, Odom John AR, LaBeaud AD. Pediatric tropical medicine: The neglected diseases of children. PLoS Negl Trop Dis. 2019 05; 13(5):e0007008. PMID: 31071087.
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Hotez PJ, Fenwick A, Molyneux DH. Collateral Benefits of Preventive Chemotherapy - Expanding the War on Neglected Tropical Diseases. N Engl J Med. 2019 Jun 20; 380(25):2389-2391. PMID: 31067365.
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Hotez P. The physician-scientist: defending vaccines and combating antiscience. J Clin Invest. 2019 04 29; 129(6):2169-2171. PMID: 31033486.
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Paniz-Mondolfi AE, Tami A, Grillet ME, Márquez M, Hernández-Villena J, Escalona-Rodríguez MA, Blohm GM, Mejías I, Urbina-Medina H, Rísquez A, Castro J, Carvajal A, Walter C, López MG, Schwabl P, Hernández-Castro L, Miles MA, Hotez PJ, Lednicky J, Morris JG, Crainey J, Luz S, Ramírez JD, Sordillo E, Llewellyn M, Canache M, Araque M, Oletta J. Resurgence of Vaccine-Preventable Diseases in Venezuela as a Regional Public Health Threat in the Americas. Emerg Infect Dis. 2019 04; 25(4):625-632. PMID: 30698523.
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Hotez PJ, Harrison W, Fenwick A, Bustinduy AL, Ducker C, Sabina Mbabazi P, Engels D, Floerecke Kjetland E. Female genital schistosomiasis and HIV/AIDS: Reversing the neglect of girls and women. PLoS Negl Trop Dis. 2019 04; 13(4):e0007025. PMID: 30946746.
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Hotez PJ. Linking Tropical Infections to Hypertension: New Comorbid Disease Paradigms in Our Era of "Blue Marble Health". J Am Heart Assoc. 2019 03 19; 8(6):e03984. PMID: 30879371.
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Majid MF, Kang SJ, Hotez PJ. Resolving "worm wars": An extended comparison review of findings from key economics and epidemiological studies. PLoS Negl Trop Dis. 2019 03; 13(3):e0006940. PMID: 30845181.
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Hotez P. America and Europe's new normal: the return of vaccine-preventable diseases. Pediatr Res. 2019 06; 85(7):912-914. PMID: 30812027.
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Bailey F, Mondragon-Shem K, Haines LR, Olabi A, Alorfi A, Ruiz-Postigo JA, Alvar J, Hotez P, Adams ER, Vélez ID, Al-Salem W, Eaton J, Acosta-Serrano Á, Molyneux DH. Cutaneous leishmaniasis and co-morbid major depressive disorder: A systematic review with burden estimates. PLoS Negl Trop Dis. 2019 02; 13(2):e0007092. PMID: 30802261.
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Grillet ME, Hernández-Villena JV, Llewellyn MS, Paniz-Mondolfi AE, Tami A, Vincenti-Gonzalez MF, Marquez M, Mogollon-Mendoza AC, Hernandez-Pereira CE, Plaza-Morr JD, Blohm G, Grijalva MJ, Costales JA, Ferguson HM, Schwabl P, Hernandez-Castro LE, Lamberton PHL, Streicker DG, Haydon DT, Miles MA, Acosta-Serrano A, Acquattela H, Basañez MG, Benaim G, Colmenares LA, Conn JE, Espinoza R, Freilij H, Graterol-Gil MC, Hotez PJ, Kato H, Lednicky JA, Martinez CE, Mas-Coma S, Morris JG, Navarro JC, Ramirez JL, Rodriguez M, Urbina JA, Villegas L, Segovia MJ, Carrasco HJ, Crainey JL, Luz SLB, Moreno JD, Noya Gonzalez OO, Ramírez JD, Alarcón-de Noya B. Venezuela's humanitarian crisis, resurgence of vector-borne diseases, and implications for spillover in the region. Lancet Infect Dis. 2019 05; 19(5):e149-e161. PMID: 30799251.
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Alonso-Padilla J, Cortés-Serra N, Pinazo MJ, Bottazzi ME, Abril M, Barreira F, Sosa-Estani S, Hotez PJ, Gascón J. Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America. Expert Rev Anti Infect Ther. 2019 03; 17(3):145-157. PMID: 30712412.
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Rees CA, Hotez PJ, Monuteaux MC, Niescierenko M, Bourgeois FT. Neglected tropical diseases in children: An assessment of gaps in research prioritization. PLoS Negl Trop Dis. 2019 01; 13(1):e0007111. PMID: 30695020.
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Wang L, Zou Y, Zhu X, Bottazzi ME, Hotez PJ, Zhan B. China's shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative. PLoS Negl Trop Dis. 2019 01; 13(1):e0006946. PMID: 30677027.
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Hotez PJ, Biritwum NK, Fenwick A, Molyneux DH, Sachs JD. Ghana: Accelerating neglected tropical disease control in a setting of economic development. PLoS Negl Trop Dis. 2019 01; 13(1):e0007005. PMID: 30653493.
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Weatherhead JE, Porter P, Coffey A, Haydel D, Versteeg L, Zhan B, Gazzinelli Guimarães AC, Fujiwara R, Jaramillo AM, Bottazzi ME, Hotez PJ, Corry DB, Beaumier CM. Ascaris Larval Infection and Lung Invasion Directly Induce Severe Allergic Airway Disease in Mice. Infect Immun. 2018 12; 86(12). PMID: 30249744.
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Hotez PJ, Bottazzi ME, Bethony J, Diemert DD. Advancing the Development of a Human Schistosomiasis Vaccine. Trends Parasitol. 2019 02; 35(2):104-108. PMID: 30455112.
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Gazzinelli-Guimarães AC, Gazzinelli-Guimarães PH, Nogueira DS, Oliveira FMS, Barbosa FS, Amorim CCO, Cardoso MS, Kraemer L, Caliari MV, Akamatsu MA, Ho PL, Jones KM, Weatherhead J, Bottazzi ME, Hotez PJ, Zhan B, Bartholomeu DC, Russo RC, Bueno LL, Fujiwara RT. IgG Induced by Vaccination With Ascaris suum Extracts Is Protective Against Infection. Front Immunol. 2018; 9:2535. PMID: 30473693.
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Blum AJ, Majid MF, Hotez PJ. Pakistan: A nation held back by NTDs. PLoS Negl Trop Dis. 2018 10; 12(10):e0006751. PMID: 30335756.
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Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR. Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils. PLoS Negl Trop Dis. 2018 10; 12(10):e0006772. PMID: 30296268.
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Hotez PJ. Crafting your scientist brand. PLoS Biol. 2018 10; 16(10):e3000024. PMID: 30289876.
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Gunter SM, Versteeg L, Jones KM, Keegan BP, Strych U, Bottazzi ME, Hotez PJ, Brown EL. Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production. Parasite Immunol. 2018 Nov; 40(11):e12585. PMID: 30132929.
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de la Cruz JJ, Villanueva-Lizama L, Dzul-Huchim V, Ramírez-Sierra MJ, Martinez-Vega P, Rosado-Vallado M, Ortega-Lopez J, Flores-Pucheta CI, Gillespie P, Zhan B, Bottazzi ME, Hotez PJ, Dumonteil E. Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice. Hum Vaccin Immunother. 2019; 15(1):210-219. PMID: 30192702.
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Hotez PJ. Minutes to midnight: Turning back the Doomsday Clock through neglected disease vaccine diplomacy. PLoS Negl Trop Dis. 2018 09; 12(9):e0006676. PMID: 30235204.
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Caplan AL, Hotez PJ. Science in the fight to uphold the rights of children. PLoS Biol. 2018 09; 16(9):e3000010. PMID: 30226835.
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Hotez PJ. The rise of leishmaniasis in the twenty-first century. Trans R Soc Trop Med Hyg. 2018 09 01; 112(9):421-422. PMID: 30239944.
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Briggs N, Wei J, Versteeg L, Zhan B, Keegan B, Damania A, Pollet J, Hayes KS, Beaumier C, Seid CA, Leong J, Grencis RK, Bottazzi ME, Sastry KJ, Hotez PJ. Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm. PLoS Pathog. 2018 08; 14(8):e1007273. PMID: 30153307.
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Almutairi MM, Alsalem WS, Hassanain M, Hotez PJ. Hajj, Umrah, and the neglected tropical diseases. PLoS Negl Trop Dis. 2018 08; 12(8):e0006539. PMID: 30114210.
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Diemert DJ, Bottazzi ME, Plieskatt J, Hotez PJ, Bethony JM. Lessons along the Critical Path: Developing Vaccines against Human Helminths. Trends Parasitol. 2018 09; 34(9):747-758. PMID: 30064902.
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Blum AJ, Hotez PJ. Global "worming": Climate change and its projected general impact on human helminth infections. PLoS Negl Trop Dis. 2018 07; 12(7):e0006370. PMID: 30024871.
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Olive JK, Hotez PJ, Damania A, Nolan MS. Correction: The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties. PLoS Med. 2018 07; 15(7):e1002616. PMID: 29979682.
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Hotez PJ, Wolf JE. Vaccines Hesitancy and the Dermatologist. Skinmed. 2018; 16(4):219-221. PMID: 30207522.
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Hotez PJ. Advancing biological therapies against a rising tide of American anti-science and other external threats. Expert Opin Biol Ther. 2018 07; 18(sup1):5-7. PMID: 30063855.
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Kang S, Damania A, Majid MF, Hotez PJ. Extending the global worm index and its links to human development and child education. PLoS Negl Trop Dis. 2018 06; 12(6):e0006322. PMID: 29927931.
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Cromwell EA, Roy S, Sankara DP, Weiss A, Stanaway J, Goldberg E, Pigott DM, Larson H, Vollset SE, Krohn K, Foreman K, Hotez P, Bhutta Z, Bekele BB, Edessa D, Kassembaum N, Mokdad A, Murray CJL, Hay SI. Slaying little dragons: the impact of the Guinea Worm Eradication Program on dracunculiasis disability averted from 1990 to 2016. Gates Open Res. 2018 Jun 18; 2:30. PMID: 30234196.
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Olive JK, Hotez PJ, Damania A, Nolan MS. The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties. PLoS Med. 2018 06; 15(6):e1002578. PMID: 29894470.
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Hotez PJ, Fenwick A, Ray SE, Hay SI, Molyneux DH. "Rapid impact" 10 years after: The first "decade" (2006-2016) of integrated neglected tropical disease control. PLoS Negl Trop Dis. 2018 05; 12(5):e0006137. PMID: 29795551.
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Hotez PJ. The global fight to develop antipoverty vaccines in the anti-vaccine era. Hum Vaccin Immunother. 2018; 14(9):2128-2131. PMID: 29393710.
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Du RY, Stanaway JD, Hotez PJ. Could violent conflict derail the London Declaration on NTDs? PLoS Negl Trop Dis. 2018 04; 12(4):e0006136. PMID: 29672514.
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Mokdad AH, Ballestros K, Echko M, Glenn S, Olsen HE, Mullany E, Lee A, Khan AR, Ahmadi A, Ferrari AJ, Kasaeian A, Werdecker A, Carter A, Zipkin B, Sartorius B, Serdar B, Sykes BL, Troeger C, Fitzmaurice C, Rehm CD, Santomauro D, Kim D, Colombara D, Schwebel DC, Tsoi D, Kolte D, Nsoesie E, Nichols E, Oren E, Charlson FJ, Patton GC, Roth GA, Hosgood HD, Whiteford HA, Kyu H, Erskine HE, Huang H, Martopullo I, Singh JA, Nachega JB, Sanabria JR, Abbas K, Ong K, Tabb K, Krohn KJ, Cornaby L, Degenhardt L, Moses M, Farvid M, Griswold M, Criqui M, Bell M, Nguyen M, Wallin M, Mirarefin M, Qorbani M, Younis M, Fullman N, Liu P, Briant P, Gona P, Havmoller R, Leung R, Kimokoti R, Bazargan-Hejazi S, Hay SI, Yadgir S, Biryukov S, Vollset SE, Alam T, Frank T, Farid T, Miller T, Vos T, Bärnighausen T, Gebrehiwot TT, Yano Y, Al-Aly Z, Mehari A, Handal A, Kandel A, Anderson B, Biroscak B, Mozaffarian D, Dorsey ER, Ding EL, Park EK, Wagner G, Hu G, Chen H, Sunshine JE, Khubchandani J, Leasher J, Leung J, Salomon J, Unutzer J, Cahill L, Cooper L, Horino M, Brauer M, Breitborde N, Hotez P, Topor-Madry R, Soneji S, Stranges S, James S, Amrock S, Jayaraman S, Patel T, Akinyemiju T, Skirbekk V, Kinfu Y, Bhutta Z, Jonas JB, Murray CJL. The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States. JAMA. 2018 04 10; 319(14):1444-1472. PMID: 29634829.
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Hotez PJ. Human Parasitology and Parasitic Diseases: Heading Towards 2050. Adv Parasitol. 2018; 100:29-38. PMID: 29753341.
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Jones K, Versteeg L, Damania A, Keegan B, Kendricks A, Pollet J, Cruz-Chan JV, Gusovsky F, Hotez PJ, Bottazzi ME. Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease. Infect Immun. 2018 04; 86(4). PMID: 29311242.
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Hotez PJ, Damania A. India's neglected tropical diseases. PLoS Negl Trop Dis. 2018 03; 12(3):e0006038. PMID: 29565970.
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Bouchery T, Filbey K, Shepherd A, Chandler J, Patel D, Schmidt A, Camberis M, Peignier A, Smith AAT, Johnston K, Painter G, Pearson M, Giacomin P, Loukas A, Bottazzi ME, Hotez P, LeGros G. A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathog. 2018 03; 14(3):e1006931. PMID: 29566094.
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Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ. Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen. Vaccine. 2018 03 27; 36(14):1853-1862. PMID: 29496347.
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Hotez PJ. Modern Sunni-Shia conflicts and their neglected tropical diseases. PLoS Negl Trop Dis. 2018 02; 12(2):e0006008. PMID: 29447164.
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Villanueva-Lizama LE, Cruz-Chan JV, Aguilar-Cetina ADC, Herrera-Sanchez LF, Rodriguez-Perez JM, Rosado-Vallado ME, Ramirez-Sierra MJ, Ortega-Lopez J, Jones K, Hotez P, Bottazzi ME, Dumonteil E. Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico. PLoS Negl Trop Dis. 2018 01; 12(1):e0006240. PMID: 29377898.
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Hotez PJ. The rise of neglected tropical diseases in the "new Texas". PLoS Negl Trop Dis. 2018 01; 12(1):e0005581. PMID: 29346369.
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Hotez PJ. Empowering Girls and Women through Hookworm Prevention. Am J Trop Med Hyg. 2018 05; 98(5):1211-1212. PMID: 29611502.
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Hotez PJ. Ten failings in global neglected tropical diseases control. PLoS Negl Trop Dis. 2017 12; 11(12):e0005896. PMID: 29267282.
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Biter AB, Weltje S, Hudspeth EM, Seid CA, McAtee CP, Chen WH, Pollet JB, Strych U, Hotez PJ, Bottazzi ME. Characterization and Stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a Candidate Antigen for a Therapeutic Vaccine Against Chagas Disease. J Pharm Sci. 2018 05; 107(5):1468-1473. PMID: 29274820.
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Akinyemiju T, Abera S, Ahmed M, Alam N, Alemayohu MA, Allen C, Al-Raddadi R, Alvis-Guzman N, Amoako Y, Artaman A, Ayele TA, Barac A, Bensenor I, Berhane A, Bhutta Z, Castillo-Rivas J, Chitheer A, Choi JY, Cowie B, Dandona L, Dandona R, Dey S, Dicker D, Phuc H, Ekwueme DU, Zaki MS, Fischer F, Fürst T, Hancock J, Hay SI, Hotez P, Jee SH, Kasaeian A, Khader Y, Khang YH, Kumar A, Kutz M, Larson H, Lopez A, Lunevicius R, Malekzadeh R, McAlinden C, Meier T, Mendoza W, Mokdad A, Moradi-Lakeh M, Nagel G, Nguyen Q, Nguyen G, Ogbo F, Patton G, Pereira DM, Pourmalek F, Qorbani M, Radfar A, Roshandel G, Salomon JA, Sanabria J, Sartorius B, Satpathy M, Sawhney M, Sepanlou S, Shackelford K, Shore H, Sun J, Mengistu DT, Topór-Madry R, Tran B, Vlassov V, Vollset SE, Vos T, Wakayo T, Weiderpass E, Werdecker A, Yonemoto N, Younis M, Yu C, Zaidi Z, Zhu L, Murray CJL, Naghavi M, Fitzmaurice C. The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study 2015. JAMA Oncol. 2017 12 01; 3(12):1683-1691. PMID: 28983565.
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Hotez PJ, Jackson Lee S. US Gulf Coast states: The rise of neglected tropical diseases in "flyover nation". PLoS Negl Trop Dis. 2017 11; 11(11):e0005744. PMID: 29145403.
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Hotez PJ. The poverty-related neglected diseases: Why basic research matters. PLoS Biol. 2017 Nov; 15(11):e2004186. PMID: 29121043.
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Hotez PJ. "Melanie's measles" is deadly and causes permanent neurologic impairment. Microbes Infect. 2018 02; 20(2):63-64. PMID: 29126876.
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Hotez PJ. New paths for PLOS Neglected Tropical Diseases: Continuing a tradition of innovation and commitment to the poor. PLoS Negl Trop Dis. 2017 10; 11(10):e0005862. PMID: 29073134.
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McKenna ML, McAtee S, Bryan PE, Jeun R, Ward T, Kraus J, Bottazzi ME, Hotez PJ, Flowers CC, Mejia R. Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. Am J Trop Med Hyg. 2017 Nov; 97(5):1623-1628. PMID: 29016326.
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Karun V, Hotez PJ, Rosengart TK. Global surgery and the neglected tropical diseases. PLoS Negl Trop Dis. 2017 09; 11(9):e0005563. PMID: 28957317.
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Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Onchocerca volvulus: The Road from Basic Biology to a Vaccine. Trends Parasitol. 2018 01; 34(1):64-79. PMID: 28958602.
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Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Neurol. 2017 11; 16(11):877-897. PMID: 28931491.
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Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16; 390(10100):1260-1344. PMID: 28919118.
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Hotez PJ. The Neglected Diseases: Will a 'New World Order' Reverse Global Gains? Int Health. 2017 Sep 01; 9(5):267-268. PMID: 28911132.
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Lo NC, Hotez PJ. Public Health and Economic Consequences of Vaccine Hesitancy for Measles in the United States. JAMA Pediatr. 2017 09 01; 171(9):887-892. PMID: 28738137.
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Hotez PJ, Murray KO. Dengue, West Nile virus, chikungunya, Zika-and now Mayaro? PLoS Negl Trop Dis. 2017 08; 11(8):e0005462. PMID: 28859086.
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Hotez PJ. Global deworming: moving past albendazole and mebendazole. Lancet Infect Dis. 2017 11; 17(11):1101-1102. PMID: 28864029.
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Konduri V, Halpert MM, Liang D, Levitt JM, Cruz-Chan JV, Zhan B, Bottazzi ME, Hotez PJ, Jones KM, Decker WK. Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy. Infect Immun. 2017 09; 85(9). PMID: 28674032.
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Liu Z, Kelleher A, Tabb S, Wei J, Pollet J, Hotez PJ, Bottazzi ME, Zhan B, Asojo OA. Identification, Characterization, and Structure of Tm16 from Trichuris muris. J Parasitol Res. 2017; 2017:4342789. PMID: 28884022.
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Bailey F, Mondragon-Shem K, Hotez P, Ruiz-Postigo JA, Al-Salem W, Acosta-Serrano Á, Molyneux DH. A new perspective on cutaneous leishmaniasis-Implications for global prevalence and burden of disease estimates. PLoS Negl Trop Dis. 2017 08; 11(8):e0005739. PMID: 28796782.
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Herricks JR, Hotez PJ, Wanga V, Coffeng LE, Haagsma JA, Basáñez MG, Buckle G, Budke CM, Carabin H, Fèvre EM, Fürst T, Halasa YA, King CH, Murdoch ME, Ramaiah KD, Shepard DS, Stolk WA, Undurraga EA, Stanaway JD, Naghavi M, Murray CJL. The global burden of disease study 2013: What does it mean for the NTDs? PLoS Negl Trop Dis. 2017 08; 11(8):e0005424. PMID: 28771480.
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Ma G, Holland CV, Wang T, Hofmann A, Fan CK, Maizels RM, Hotez PJ, Gasser RB. Human toxocariasis. Lancet Infect Dis. 2018 01; 18(1):e14-e24. PMID: 28781085.
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Weatherhead JE, Hotez PJ, Mejia R. The Global State of Helminth Control and Elimination in Children. Pediatr Clin North Am. 2017 08; 64(4):867-877. PMID: 28734515.
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Wei J, Versteeg L, Liu Z, Keegan B, Gazzinelli-Guimarães AC, Fujiwara RT, Briggs N, Jones KM, Strych U, Beaumier CM, Bottazzi ME, Hotez PJ, Zhan B. Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response. PLoS Negl Trop Dis. 2017 Jul; 11(7):e0005769. PMID: 28708895.
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Hotez PJ, Basáñez MG, Acosta-Serrano A, Grillet ME. Venezuela and its rising vector-borne neglected diseases. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005423. PMID: 28662038.
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Fitzpatrick MC, Singer BH, Hotez PJ, Galvani AP. Saving lives efficiently across sectors: the need for a Congressional cost-effectiveness committee. Lancet. 2017 Nov 25; 390(10110):2410-2412. PMID: 28669643.
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Gunter SM, Jones KM, Seid CA, Essigmann HT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Brown EL. Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis. J Parasitol. 2017 10; 103(5):579-583. PMID: 28581897.
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Hotez PJ. Russian-United States vaccine science diplomacy: Preserving the legacy. PLoS Negl Trop Dis. 2017 May; 11(5):e0005320. PMID: 28542186.
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Roth GA, Johnson C, Abajobir A, Abd-Allah F, Abera SF, Abyu G, Ahmed M, Aksut B, Alam T, Alam K, Alla F, Alvis-Guzman N, Amrock S, Ansari H, Ärnlöv J, Asayesh H, Atey TM, Avila-Burgos L, Awasthi A, Banerjee A, Barac A, Bärnighausen T, Barregard L, Bedi N, Belay Ketema E, Bennett D, Berhe G, Bhutta Z, Bitew S, Carapetis J, Carrero JJ, Malta DC, Castañeda-Orjuela CA, Castillo-Rivas J, Catalá-López F, Choi JY, Christensen H, Cirillo M, Cooper L, Criqui M, Cundiff D, Damasceno A, Dandona L, Dandona R, Davletov K, Dharmaratne S, Dorairaj P, Dubey M, Ehrenkranz R, El Sayed Zaki M, Faraon EJA, Esteghamati A, Farid T, Farvid M, Feigin V, Ding EL, Fowkes G, Gebrehiwot T, Gillum R, Gold A, Gona P, Gupta R, Habtewold TD, Hafezi-Nejad N, Hailu T, Hailu GB, Hankey G, Hassen HY, Abate KH, Havmoeller R, Hay SI, Horino M, Hotez PJ, Jacobsen K, James S, Javanbakht M, Jeemon P, John D, Jonas J, Kalkonde Y, Karimkhani C, Kasaeian A, Khader Y, Khan A, Khang YH, Khera S, Khoja AT, Khubchandani J, Kim D, Kolte D, Kosen S, Krohn KJ, Kumar GA, Kwan GF, Lal DK, Larsson A, Linn S, Lopez A, Lotufo PA, El Razek HMA, Malekzadeh R, Mazidi M, Meier T, Meles KG, Mensah G, Meretoja A, Mezgebe H, Miller T, Mirrakhimov E, Mohammed S, Moran AE, Musa KI, Narula J, Neal B, Ngalesoni F, Nguyen G, Obermeyer CM, Owolabi M, Patton G, Pedro J, Qato D, Qorbani M, Rahimi K, Rai RK, Rawaf S, Ribeiro A, Safiri S, Salomon JA, Santos I, Santric Milicevic M, Sartorius B, Schutte A, Sepanlou S, Shaikh MA, Shin MJ, Shishehbor M, Shore H, Silva DAS, Sobngwi E, Stranges S, Swaminathan S, Tabarés-Seisdedos R, Tadele Atnafu N, Tesfay F, Thakur JS, Thrift A, Topor-Madry R, Truelsen T, Tyrovolas S, Ukwaja KN, Uthman O, Vasankari T, Vlassov V, Vollset SE, Wakayo T, Watkins D, Weintraub R, Werdecker A, Westerman R, Wiysonge CS, Wolfe C, Workicho A, Xu G, Yano Y, Yip P, Yonemoto N, Younis M, Yu C, Vos T, Naghavi M, Murray C. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015. J Am Coll Cardiol. 2017 Jul 04; 70(1):1-25. PMID: 28527533.
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Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, Li G, Peng J, Correa-Oliveira R, Hotez P, Bethony J. Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. PLoS Negl Trop Dis. 2017 05; 11(5):e0005574. PMID: 28464026.
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Hotez PJ. Neglected tropical diseases in the time of Dr Tedros. Trans R Soc Trop Med Hyg. 2017 05 01; 111(5):189-190. PMID: 28957469.
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Hotez PJ. Can the SDGs and GHSA achieve synergy? J Public Health Policy. 2017 May; 38(2):269-270. PMID: 28533528.
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Hotez PJ, Damania A, Barua A, Stanaway J. The first "London Declaration": The Commonwealth and its neglected tropical diseases. PLoS Negl Trop Dis. 2017 Apr; 11(4):e0005321. PMID: 28448487.
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Lee BY, Alfaro-Murillo JA, Parpia AS, Asti L, Wedlock PT, Hotez PJ, Galvani AP. The potential economic burden of Zika in the continental United States. PLoS Negl Trop Dis. 2017 04; 11(4):e0005531. PMID: 28448488.
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Chen WH, Chag SM, Poongavanam MV, Biter AB, Ewere EA, Rezende W, Seid CA, Hudspeth EM, Pollet J, McAtee CP, Strych U, Bottazzi ME, Hotez PJ. Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate. J Pharm Sci. 2017 08; 106(8):1961-1970. PMID: 28456726.
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Hotez P, Aksoy S. PLOS Neglected Tropical Diseases: Ten years of progress in neglected tropical disease control and elimination … More or less. PLoS Negl Trop Dis. 2017 04; 11(4):e0005355. PMID: 28426662.
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Hotez P, Bundy DAP. The PLOS Neglected Tropical Diseases decade. PLoS Negl Trop Dis. 2017 Apr; 11(4):e0005479. PMID: 28426658.
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Hotez PJ, Aksoy S. Will a new 2017 global leadership commit to NTDs? PLoS Negl Trop Dis. 2017 Mar; 11(3):e0005309. PMID: 28333927.
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Asojo OA, Kelleher A, Liu Z, Pollet J, Hudspeth EM, Rezende WC, Groen MJ, Seid CA, Abdeladhim M, Townsend S, de Castro W, Mendes-Sousa A, Bartholomeu DC, Fujiwara RT, Bottazzi ME, Hotez PJ, Zhan B, Oliveira F, Kamhawi S, Valenzuela JG. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis. PLoS Negl Trop Dis. 2017 03; 11(3):e0005374. PMID: 28278244.
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Hotez PJ. Developing and financing neglected disease vaccines in our new era of "blue marble health" and the anthropocene epoch. Vaccine. 2017 09 25; 35(40):5403-5405. PMID: 28262333.
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Hotez PJ. Global urbanization and the neglected tropical diseases. PLoS Negl Trop Dis. 2017 Feb; 11(2):e0005308. PMID: 28231246.
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Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine. PLoS Negl Trop Dis. 2017 02; 11(2):e0005385. PMID: 28192438.
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Pollet J, Versteeg L, Rezende W, Strych U, Gusovsky F, Hotez PJ, Bottazzi ME. A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations. Vaccine. 2017 03 07; 35(10):1410-1416. PMID: 28190745.
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Eppes C, Rac M, Dunn J, Versalovic J, Murray KO, Suter MA, Sanz Cortes M, Espinoza J, Seferovic MD, Lee W, Hotez P, Mastrobattista J, Clark SL, Belfort MA, Aagaard KM. Testing for Zika virus infection in pregnancy: key concepts to deal with an emerging epidemic. Am J Obstet Gynecol. 2017 03; 216(3):209-225. PMID: 28126366.
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Hotez PJ, Damania A, Naghavi M. Paying for Worms. PLoS Negl Trop Dis. 2016 12; 10(12):e0005092. PMID: 28033369.
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Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R, Croese J, Bethony JM. Hookworm infection. Nat Rev Dis Primers. 2016 12 08; 2:16088. PMID: 27929101.
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Hotez PJ, Kassem M. Egypt: Its Artists, Intellectuals, and Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Dec; 10(12):e0005072. PMID: 27906985.
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Lo NC, Addiss DG, Hotez PJ, King CH, Stothard JR, Evans DS, Colley DG, Lin W, Coulibaly JT, Bustinduy AL, Raso G, Bendavid E, Bogoch II, Fenwick A, Savioli L, Molyneux D, Utzinger J, Andrews JR. A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now. Lancet Infect Dis. 2017 02; 17(2):e64-e69. PMID: 27914852.
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Hotez PJ. Zika Virus Is More Like Rubella Than Human Immunodeficiency Virus-Reply. JAMA Pediatr. 2016 11 01; 170(11):1116. PMID: 27617894.
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Hotez PJ, Damania A, Naghavi M. Blue Marble Health and the Global Burden of Disease Study 2013. PLoS Negl Trop Dis. 2016 Oct; 10(10):e0004744. PMID: 27788134.
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Navarro S, Pickering DA, Ferreira IB, Jones L, Ryan S, Troy S, Leech A, Hotez PJ, Zhan B, Laha T, Prentice R, Sparwasser T, Croese J, Engwerda CR, Upham JW, Julia V, Giacomin PR, Loukas A. Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Sci Transl Med. 2016 10 26; 8(362):362ra143. PMID: 27797959.
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Hotez PJ. Texas and Its Measles Epidemics. PLoS Med. 2016 Oct; 13(10):e1002153. PMID: 27780206.
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McAtee CP, Seid CA, Hammond M, Hudspeth E, Keegan BP, Liu Z, Wei J, Zhan B, Arjona-Sabido R, Cruz-Chan V, Dumonteil E, Hotez PJ, Bottazzi ME. Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis. Protein Expr Purif. 2017 02; 130:129-136. PMID: 27773761.
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Seid CA, Jones KM, Pollet J, Keegan B, Hudspeth E, Hammond M, Wei J, McAtee CP, Versteeg L, Gutierrez A, Liu Z, Zhan B, Respress JL, Strych U, Bottazzi ME, Hotez PJ. Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease. Hum Vaccin Immunother. 2017 03 04; 13(3):621-633. PMID: 27737611.
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Jaffer A, Hotez PJ. Somalia: A Nation at the Crossroads of Extreme Poverty, Conflict, and Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Sep; 10(9):e0004670. PMID: 27685261.
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Wei J, Damania A, Gao X, Liu Z, Mejia R, Mitreva M, Strych U, Bottazzi ME, Hotez PJ, Zhan B. The hookworm Ancylostoma ceylanicum intestinal transcriptome provides a platform for selecting drug and vaccine candidates. Parasit Vectors. 2016 Sep 27; 9(1):518. PMID: 27677574.
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Briggs N, Weatherhead J, Sastry KJ, Hotez PJ. The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections. PLoS Negl Trop Dis. 2016 09; 10(9):e0004944. PMID: 27632204.
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Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, Lee BY. The Global Economic and Health Burden of Human Hookworm Infection. PLoS Negl Trop Dis. 2016 09; 10(9):e0004922. PMID: 27607360.
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Mehta P, Hotez PJ. NTD and NCD Co-morbidities: The Example of Dengue Fever. PLoS Negl Trop Dis. 2016 Aug; 10(8):e0004619. PMID: 27561091.
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Al-Salem W, Herricks JR, Hotez PJ. A review of visceral leishmaniasis during the conflict in South Sudan and the consequences for East African countries. Parasit Vectors. 2016 08 22; 9:460. PMID: 27549162.
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Hotez PJ. What Does Zika Virus Mean for the Children of the Americas? JAMA Pediatr. 2016 08 01; 170(8):787-9. PMID: 27322491.
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Hotez PJ. The World's Great Religions and Their Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Jul; 10(7):e0004544. PMID: 27467213.
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Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice. PLoS Negl Trop Dis. 2016 07; 10(7):e0004797. PMID: 27387453.
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Hotez PJ. Southern Europe's Coming Plagues: Vector-Borne Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 06; 10(6):e0004243. PMID: 27362640.
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Kim H, Marks F, Novakovic U, Hotez PJ, Black RE. Multistakeholder partnerships with the Democratic Peoples' Republic of Korea to improve childhood immunisation: A perspective from global health equity and political determinants of health equity. Trop Med Int Health. 2016 Aug; 21(8):965-972. PMID: 27159122.
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Hotez PJ. Will Zika return to the 'Old World'? Microbes Infect. 2016 09; 18(9):527-8. PMID: 27242327.
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Du R, Hotez PJ, Al-Salem WS, Acosta-Serrano A. Old World Cutaneous Leishmaniasis and Refugee Crises in the Middle East and North Africa. PLoS Negl Trop Dis. 2016 05; 10(5):e0004545. PMID: 27227772.
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Hotez PJ. Zika in the United States of America and a Fateful 1969 Decision. PLoS Negl Trop Dis. 2016 05; 10(5):e0004765. PMID: 27227971.
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Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Human anthelminthic vaccines: Rationale and challenges. Vaccine. 2016 06 24; 34(30):3549-55. PMID: 27171753.
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Hotez PJ. Neglected Tropical Diseases in the Anthropocene: The Cases of Zika, Ebola, and Other Infections. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004648. PMID: 27058728.
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Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004586. PMID: 27045170.
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Hotez PJ. The South China Sea and Its Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Mar; 10(3):e0004395. PMID: 27031342.
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Hotez PJ, Beaumier CM, Gillespie PM, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. 2016 06 03; 34(26):3001-3005. PMID: 27040400.
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Merrifield M, Hotez PJ, Beaumier CM, Gillespie P, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent human schistosomiasis. Vaccine. 2016 06 03; 34(26):2988-2991. PMID: 27036511.
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Beaumier CM, Gillespie PM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for Chagas disease. Vaccine. 2016 06 03; 34(26):2996-3000. PMID: 27026146.
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Bartsch SM, Hotez PJ, Hertenstein DL, Diemert DJ, Zapf KM, Bottazzi ME, Bethony JM, Brown ST, Lee BY. Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting. Vaccine. 2016 Apr 27; 34(19):2197-206. PMID: 27002501.
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Gillespie PM, Beaumier CM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for leishmaniasis. Vaccine. 2016 06 03; 34(26):2992-2995. PMID: 26973063.
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Hotez PJ, Pecoul B, Rijal S, Boehme C, Aksoy S, Malecela M, Tapia-Conyer R, Reeder JC. Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies. PLoS Negl Trop Dis. 2016 Mar; 10(3):e0003895. PMID: 26934395.
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Barry MA, Murray KO, Hotez PJ, Jones KM. Impact of vectorborne parasitic neglected tropical diseases on child health. Arch Dis Child. 2016 07; 101(7):640-7. PMID: 26921274.
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Pecoul B, Batista C, Stobbaerts E, Ribeiro I, Vilasanjuan R, Gascon J, Pinazo MJ, Moriana S, Gold S, Pereiro A, Navarro M, Torrico F, Bottazzi ME, Hotez PJ. The BENEFIT Trial: Where Do We Go from Here? PLoS Negl Trop Dis. 2016 Feb; 10(2):e0004343. PMID: 26913759.
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Barry MA, Wang Q, Jones KM, Heffernan MJ, Buhaya MH, Beaumier CM, Keegan BP, Zhan B, Dumonteil E, Bottazzi ME, Hotez PJ. A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Hum Vaccin Immunother. 2016 04 02; 12(4):976-87. PMID: 26890466.
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Hudspeth EM, Wang Q, Seid CA, Hammond M, Wei J, Liu Z, Zhan B, Pollet J, Heffernan MJ, McAtee CP, Engler DA, Matsunami RK, Strych U, Asojo OA, Hotez PJ, Bottazzi ME. Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties. Hum Vaccin Immunother. 2016 07 02; 12(7):1707-20. PMID: 26839079.
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Garcia MN, Hernandez D, Gorchakov R, Murray KO, Hotez PJ. The 1899 United States Kissing Bug Epidemic. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004117. PMID: 26719888.
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Hotez PJ, Herricks JR. Impact of the Neglected Tropical Diseases on Human Development in the Organisation of Islamic Cooperation Nations. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0003782. PMID: 26606509.
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Gunter SM, Jones KM, Zhan B, Essigmann HT, Murray KO, Garcia MN, Gorchakov R, Bottazzi ME, Hotez PJ, Brown EL. Identification and Characterization of the Trypanosoma cruzi B-cell Superantigen Tc24. Am J Trop Med Hyg. 2016 Jan; 94(1):114-121. PMID: 26598565.
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Garcia MN, Woc-Colburn L, Aguilar D, Hotez PJ, Murray KO. Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0003981. PMID: 26540273.
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Zhan B, Ajmera R, Geiger SM, Gonçalves MT, Liu Z, Wei J, Wilkins PP, Fujiwara R, Gazzinelli-Guimaraes PH, Bottazzi ME, Hotez P. Identification of immunodominant antigens for the laboratory diagnosis of toxocariasis. Trop Med Int Health. 2015 Dec; 20(12):1787-96. PMID: 26426162.
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Anderson JP, Rascoe LN, Levert K, Chastain HM, Reed MS, Rivera HN, McAuliffe I, Zhan B, Wiegand RE, Hotez PJ, Wilkins PP, Pohl J, Handali S. Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc-CTL-1 and Tc-TES-26. PLoS Negl Trop Dis. 2015; 9(10):e0004168. PMID: 26485145.
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Hotez PJ. Vaccine Science Diplomacy: Expanding Capacity to Prevent Emerging and Neglected Tropical Diseases Arising from Islamic State (IS)--Held Territories. PLoS Negl Trop Dis. 2015 Sep; 9(9):e0003852. PMID: 26402466.
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Hotez PJ, Bottazzi ME, Strych U. New Vaccines for the World's Poorest People. Annu Rev Med. 2016; 67:405-17. PMID: 26356803.
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Murray KO, Fischer RS, Chavarria D, Duttmann C, Garcia MN, Gorchakov R, Hotez PJ, Jiron W, Leibler JH, Lopez JE, Mandayam S, Marin A, Sheleby J. Mesoamerican nephropathy: a neglected tropical disease with an infectious etiology? Microbes Infect. 2015 Oct; 17(10):671-5. PMID: 26320026.
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Murray CJ, Barber RM, Foreman KJ, Abbasoglu Ozgoren A, Abd-Allah F, Abera SF, Aboyans V, Abraham JP, Abubakar I, Abu-Raddad LJ, Abu-Rmeileh NM, Achoki T, Ackerman IN, Ademi Z, Adou AK, Adsuar JC, Afshin A, Agardh EE, Alam SS, Alasfoor D, Albittar MI, Alegretti MA, Alemu ZA, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allebeck P, Almazroa MA, Alsharif U, Alvarez E, Alvis-Guzman N, Amare AT, Ameh EA, Amini H, Ammar W, Anderson HR, Anderson BO, Antonio CA, Anwari P, Arnlöv J, Arsic Arsenijevic VS, Artaman A, Asghar RJ, Assadi R, Atkins LS, Avila MA, Awuah B, Bachman VF, Badawi A, Bahit MC, Balakrishnan K, Banerjee A, Barker-Collo SL, Barquera S, Barregard L, Barrero LH, Basu A, Basu S, Basulaiman MO, Beardsley J, Bedi N, Beghi E, Bekele T, Bell ML, Benjet C, Bennett DA, Bensenor IM, Benzian H, Bernabé E, Bertozzi-Villa A, Beyene TJ, Bhala N, Bhalla A, Bhutta ZA, Bienhoff K, Bikbov B, Biryukov S, Blore JD, Blosser CD, Blyth FM, Bohensky MA, Bolliger IW, Bora Basara B, Bornstein NM, Bose D, Boufous S, Bourne RR, Boyers LN, Brainin M, Brayne CE, Brazinova A, Breitborde NJ, Brenner H, Briggs AD, Brooks PM, Brown JC, Brugha TS, Buchbinder R, Buckle GC, Budke CM, Bulchis A, Bulloch AG, Campos-Nonato IR, Carabin H, Carapetis JR, Cárdenas R, Carpenter DO, Caso V, Castañeda-Orjuela CA, Castro RE, Catalá-López F, Cavalleri F, Çavlin A, Chadha VK, Chang JC, Charlson FJ, Chen H, Chen W, Chiang PP, Chimed-Ochir O, Chowdhury R, Christensen H, Christophi CA, Cirillo M, Coates MM, Coffeng LE, Coggeshall MS, Colistro V, Colquhoun SM, Cooke GS, Cooper C, Cooper LT, Coppola LM, Cortinovis M, Criqui MH, Crump JA, Cuevas-Nasu L, Danawi H, Dandona L, Dandona R, Dansereau E, Dargan PI, Davey G, Davis A, Davitoiu DV, Dayama A, De Leo D, Degenhardt L, Del Pozo-Cruz B, Dellavalle RP, Deribe K, Derrett S, Des Jarlais DC, Dessalegn M, Dharmaratne SD, Dherani MK, Diaz-Torné C, Dicker D, Ding EL, Dokova K, Dorsey ER, Driscoll TR, Duan L, Duber HC, Ebel BE, Edmond KM, Elshrek YM, Endres M, Ermakov SP, Erskine HE, Eshrati B, Esteghamati A, Estep K, Faraon EJ, Farzadfar F, Fay DF, Feigin VL, Felson DT, Fereshtehnejad SM, Fernandes JG, Ferrari AJ, Fitzmaurice C, Flaxman AD, Fleming TD, Foigt N, Forouzanfar MH, Fowkes FG, Paleo UF, Franklin RC, Fürst T, Gabbe B, Gaffikin L, Gankpé FG, Geleijnse JM, Gessner BD, Gething P, Gibney KB, Giroud M, Giussani G, Gomez Dantes H, Gona P, González-Medina D, Gosselin RA, Gotay CC, Goto A, Gouda HN, Graetz N, Gugnani HC, Gupta R, Gupta R, Gutiérrez RA, Haagsma J, Hafezi-Nejad N, Hagan H, Halasa YA, Hamadeh RR, Hamavid H, Hammami M, Hancock J, Hankey GJ, Hansen GM, Hao Y, Harb HL, Haro JM, Havmoeller R, Hay SI, Hay RJ, Heredia-Pi IB, Heuton KR, Heydarpour P, Higashi H, Hijar M, Hoek HW, Hoffman HJ, Hosgood HD, Hossain M, Hotez PJ, Hoy DG, Hsairi M, Hu G, Huang C, Huang JJ, Husseini A, Huynh C, Iannarone ML, Iburg KM, Innos K, Inoue M, Islami F, Jacobsen KH, Jarvis DL, Jassal SK, Jee SH, Jeemon P, Jensen PN, Jha V, Jiang G, Jiang Y, Jonas JB, Juel K, Kan H, Karch A, Karema CK, Karimkhani C, Karthikeyan G, Kassebaum NJ, Kaul A, Kawakami N, Kazanjan K, Kemp AH, Kengne AP, Keren A, Khader YS, Khalifa SE, Khan EA, Khan G, Khang YH, Kieling C, Kim D, Kim S, Kim Y, Kinfu Y, Kinge JM, Kivipelto M, Knibbs LD, Knudsen AK, Kokubo Y, Kosen S, Krishnaswami S, Kuate Defo B, Kucuk Bicer B, Kuipers EJ, Kulkarni C, Kulkarni VS, Kumar GA, Kyu HH, Lai T, Lalloo R, Lallukka T, Lam H, Lan Q, Lansingh VC, Larsson A, Lawrynowicz AE, Leasher JL, Leigh J, Leung R, Levitz CE, Li B, Li Y, Li Y, Lim SS, Lind M, Lipshultz SE, Liu S, Liu Y, Lloyd BK, Lofgren KT, Logroscino G, Looker KJ, Lortet-Tieulent J, Lotufo PA, Lozano R, Lucas RM, Lunevicius R, Lyons RA, Ma S, Macintyre MF, Mackay MT, Majdan M, Malekzadeh R, Marcenes W, Margolis DJ, Margono C, Marzan MB, Masci JR, Mashal MT, Matzopoulos R, Mayosi BM, Mazorodze TT, Mcgill NW, Mcgrath JJ, Mckee M, Mclain A, Meaney PA, Medina C, Mehndiratta MM, Mekonnen W, Melaku YA, Meltzer M, Memish ZA, et al. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet. 2015 Nov 28; 386(10009):2145-91. PMID: 26321261.
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Hotez PJ. Correction: Blue Marble Health Redux: Neglected Tropical Diseases and Human Development in the Group of 20 (G20) Nations and Nigeria. PLoS Negl Trop Dis. 2015 Aug; 9(8):e0004035. PMID: 26288381.
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Weatherhead JE, Hotez PJ. Worm Infections in Children. Pediatr Rev. 2015 Aug; 36(8):341-52; quiz 353-4. PMID: 26232464.
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Hotez PJ. Blue Marble Health Redux: Neglected Tropical Diseases and Human Development in the Group of 20 (G20) Nations and Nigeria. PLoS Negl Trop Dis. 2015 Jul; 9(7):e0003672. PMID: 26218831.
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Hotez PJ, Peiperl L. Noncommunicable Diseases: A Globalization of Disparity? PLoS Med. 2015 Jul; 12(7):e1001859. PMID: 26218734.
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Martinez-Campos V, Martinez-Vega P, Ramirez-Sierra MJ, Rosado-Vallado M, Seid CA, Hudspeth EM, Wei J, Liu Z, Kwityn C, Hammond M, Ortega-López J, Zhan B, Hotez PJ, Bottazzi ME, Dumonteil E. Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice. Vaccine. 2015 Aug 26; 33(36):4505-12. PMID: 26192358.
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Hotez PJ. Neglected Tropical Diseases in the Ebola-Affected Countries of West Africa. PLoS Negl Trop Dis. 2015 Jun; 9(6):e0003671. PMID: 26110778.
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Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Aug 22; 386(9995):743-800. PMID: 26063472.
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Hotez PJ. Blue marble health and "the big three diseases": HIV/AIDS, tuberculosis, and malaria. Microbes Infect. 2015 Aug; 17(8):539-41. PMID: 26003523.
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Hotez PJ, Herricks JR. Helminth elimination in the pursuit of sustainable development goals: a "worm index" for human development. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003618. PMID: 25928617.
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Hotez PJ. Combating the next lethal epidemic. Science. 2015 Apr 17; 348(6232):296-7. PMID: 25883348.
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Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003575. PMID: 25880767.
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Li MG, Hotez PJ, Vrabec JT, Donovan DT. Is chronic suppurative otitis media a neglected tropical disease? PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003485. PMID: 25811602.
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Hotez PJ, Bottazzi ME, Dumonteil E, Buekens P. The Gulf of Mexico: a "hot zone" for neglected tropical diseases? PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003481. PMID: 25719411.
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Preidis GA, Hotez PJ. The newest "omics"--metagenomics and metabolomics--enter the battle against the neglected tropical diseases. PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003382. PMID: 25675250.
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Hotez PJ, Bottazzi ME, Zhan B, Makepeace BL, Klei TR, Abraham D, Taylor DW, Lustigman S. The Onchocerciasis Vaccine for Africa--TOVA--Initiative. PLoS Negl Trop Dis. 2015 Jan; 9(1):e0003422. PMID: 25634641.
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Pearson MS, Jariwala AR, Abbenante G, Plieskatt J, Wilson D, Bottazzi ME, Hotez PJ, Keegan B, Bethony JM, Loukas A. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Hum Vaccin Immunother. 2015; 11(5):1251-7. PMID: 26018444.
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Turkeltaub JA, McCarty TR, Hotez PJ. The intestinal protozoa: emerging impact on global health and development. Curr Opin Gastroenterol. 2015 Jan; 31(1):38-44. PMID: 25394233.
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Seid CA, Curti E, Jones RM, Hudspeth E, Rezende W, Pollet J, Center L, Versteeg L, Pritchard S, Musiychuk K, Yusibov V, Hotez PJ, Bottazzi ME. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Hum Vaccin Immunother. 2015; 11(6):1474-88. PMID: 25905574.
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Baring E, Hotez PJ. Yemen: fighting neglected tropical diseases against all odds. PLoS Negl Trop Dis. 2014 Dec; 8(12):e3292. PMID: 25521710.
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Jiang S, Hotez PJ. Combating the emerging viral infectious diseases. Microbes Infect. 2015 Feb; 17(2):83. PMID: 25529754.
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Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Jan 10; 385(9963):117-71. PMID: 25530442.
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Hotez PJ. The medical biochemistry of poverty and neglect. Mol Med. 2014 Dec 16; 20 Suppl 1:S31-6. PMID: 25549231.
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Hotez PJ. Global christianity and the control of its neglected tropical diseases. PLoS Negl Trop Dis. 2014 Nov; 8(11):e3135. PMID: 25412254.
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Garcia MN, Aguilar D, Gorchakov R, Rossmann SN, Montgomery SP, Rivera H, Woc-Colburn L, Hotez PJ, Murray KO. Evidence of autochthonous Chagas disease in southeastern Texas. Am J Trop Med Hyg. 2015 Feb; 92(2):325-30. PMID: 25371187.
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Ndeffo Mbah ML, Skrip L, Greenhalgh S, Hotez P, Galvani AP. Impact of Schistosoma mansoni on malaria transmission in Sub-Saharan Africa. PLoS Negl Trop Dis. 2014 Oct; 8(10):e3234. PMID: 25329403.
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Garcia MN, Murray KO, Hotez PJ, Rossmann SN, Gorchakov R, Ontiveros A, Woc-Colburn L, Bottazzi ME, Rhodes CE, Ballantyne CM, Aguilar D. Development of chagas cardiac manifestations among Texas blood donors. Am J Cardiol. 2015 Jan 01; 115(1):113-7. PMID: 25456877.
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Hotez PJ. Neglected infections of poverty in the United States and their effects on the brain. JAMA Psychiatry. 2014 Oct; 71(10):1099-100. PMID: 25103827.
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Hotez PJ. The NTDs and vaccine diplomacy in latin America: opportunities for united states foreign policy. PLoS Negl Trop Dis. 2014 Sep; 8(9):e2922. PMID: 25255437.
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Hotez PJ. Neglected parasitic infections and poverty in the United States. PLoS Negl Trop Dis. 2014 Sep; 8(9):e3012. PMID: 25188455.
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Garcia MN, Woc-Colburn L, Rossmann SN, Townsend RL, Stramer SL, Bravo M, Kamel H, Beddard R, Townsend M, Oldham R, Bottazzi ME, Hotez PJ, Murray KO. Trypanosoma cruzi screening in Texas blood donors, 2008-2012. Epidemiol Infect. 2016 Apr; 144(5):1010-3. PMID: 25170765.
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Lee RM, Moore LB, Bottazzi ME, Hotez PJ. Toxocariasis in North America: a systematic review. PLoS Negl Trop Dis. 2014 Aug; 8(8):e3116. PMID: 25166906.
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Rajagopal S, Hotez PJ, Bundy DA. Micronutrient supplementation and deworming in children with geohelminth infections. PLoS Negl Trop Dis. 2014 Aug; 8(8):e2920. PMID: 25101963.
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Hotez PJ, Fujiwara RT. Brazil's neglected tropical diseases: an overview and a report card. Microbes Infect. 2014 Aug; 16(8):601-6. PMID: 25088506.
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Hotez PJ, Peiperl L. Blue marble health: a call for papers. PLoS Med. 2014 Jul; 11(7):e1001682. PMID: 25072140.
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Hotez PJ, Alvarado M, Basáñez MG, Bolliger I, Bourne R, Boussinesq M, Brooker SJ, Brown AS, Buckle G, Budke CM, Carabin H, Coffeng LE, Fèvre EM, Fürst T, Halasa YA, Jasrasaria R, Johns NE, Keiser J, King CH, Lozano R, Murdoch ME, O'Hanlon S, Pion SD, Pullan RL, Ramaiah KD, Roberts T, Shepard DS, Smith JL, Stolk WA, Undurraga EA, Utzinger J, Wang M, Murray CJ, Naghavi M. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl Trop Dis. 2014 Jul; 8(7):e2865. PMID: 25058013.
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Murray CJ, Ortblad KF, Guinovart C, Lim SS, Wolock TM, Roberts DA, Dansereau EA, Graetz N, Barber RM, Brown JC, Wang H, Duber HC, Naghavi M, Dicker D, Dandona L, Salomon JA, Heuton KR, Foreman K, Phillips DE, Fleming TD, Flaxman AD, Phillips BK, Johnson EK, Coggeshall MS, Abd-Allah F, Abera SF, Abraham JP, Abubakar I, Abu-Raddad LJ, Abu-Rmeileh NM, Achoki T, Adeyemo AO, Adou AK, Adsuar JC, Agardh EE, Akena D, Al Kahbouri MJ, Alasfoor D, Albittar MI, Alcalá-Cerra G, Alegretti MA, Alemu ZA, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allen PJ, Alsharif U, Alvarez E, Alvis-Guzman N, Amankwaa AA, Amare AT, Amini H, Ammar W, Anderson BO, Antonio CA, Anwari P, Arnlöv J, Arsenijevic VS, Artaman A, Asghar RJ, Assadi R, Atkins LS, Badawi A, Balakrishnan K, Banerjee A, Basu S, Beardsley J, Bekele T, Bell ML, Bernabe E, Beyene TJ, Bhala N, Bhalla A, Bhutta ZA, Abdulhak AB, Binagwaho A, Blore JD, Basara BB, Bose D, Brainin M, Breitborde N, Castañeda-Orjuela CA, Catalá-López F, Chadha VK, Chang JC, Chiang PP, Chuang TW, Colomar M, Cooper LT, Cooper C, Courville KJ, Cowie BC, Criqui MH, Dandona R, Dayama A, De Leo D, Degenhardt L, Del Pozo-Cruz B, Deribe K, Des Jarlais DC, Dessalegn M, Dharmaratne SD, Dilmen U, Ding EL, Driscoll TR, Durrani AM, Ellenbogen RG, Ermakov SP, Esteghamati A, Faraon EJ, Farzadfar F, Fereshtehnejad SM, Fijabi DO, Forouzanfar MH, Fra Paleo U, Gaffikin L, Gamkrelidze A, Gankpé FG, Geleijnse JM, Gessner BD, Gibney KB, Ginawi IA, Glaser EL, Gona P, Goto A, Gouda HN, Gugnani HC, Gupta R, Gupta R, Hafezi-Nejad N, Hamadeh RR, Hammami M, Hankey GJ, Harb HL, Haro JM, Havmoeller R, Hay SI, Hedayati MT, Pi IB, Hoek HW, Hornberger JC, Hosgood HD, Hotez PJ, Hoy DG, Huang JJ, Iburg KM, Idrisov BT, Innos K, Jacobsen KH, Jeemon P, Jensen PN, Jha V, Jiang G, Jonas JB, Juel K, Kan H, Kankindi I, Karam NE, Karch A, Karema CK, Kaul A, Kawakami N, Kazi DS, Kemp AH, Kengne AP, Keren A, Kereselidze M, Khader YS, Khalifa SE, Khan EA, Khang YH, Khonelidze I, Kinfu Y, Kinge JM, Knibbs L, Kokubo Y, Kosen S, Defo BK, Kulkarni VS, Kulkarni C, Kumar K, Kumar RB, Kumar GA, Kwan GF, Lai T, Balaji AL, Lam H, Lan Q, Lansingh VC, Larson HJ, Larsson A, Lee JT, Leigh J, Leinsalu M, Leung R, Li Y, Li Y, De Lima GM, Lin HH, Lipshultz SE, Liu S, Liu Y, Lloyd BK, Lotufo PA, Machado VM, Maclachlan JH, Magis-Rodriguez C, Majdan M, Mapoma CC, Marcenes W, Marzan MB, Masci JR, Mashal MT, Mason-Jones AJ, Mayosi BM, Mazorodze TT, Mckay AC, Meaney PA, Mehndiratta MM, Mejia-Rodriguez F, Melaku YA, Memish ZA, Mendoza W, Miller TR, Mills EJ, Mohammad KA, Mokdad AH, Mola GL, Monasta L, Montico M, Moore AR, Mori R, Moturi WN, Mukaigawara M, Murthy KS, Naheed A, Naidoo KS, Naldi L, Nangia V, Narayan KM, Nash D, Nejjari C, Nelson RG, Neupane SP, Newton CR, Ng M, Nisar MI, Nolte S, Norheim OF, Nowaseb V, Nyakarahuka L, Oh IH, Ohkubo T, Olusanya BO, Omer SB, Opio JN, Orisakwe OE, Pandian JD, Papachristou C, Caicedo AJ, Patten SB, Paul VK, Pavlin BI, Pearce N, Pereira DM, Pervaiz A, Pesudovs K, Petzold M, Pourmalek F, Qato D, Quezada AD, Quistberg DA, Rafay A, Rahimi K, Rahimi-Movaghar V, Ur Rahman S, Raju M, Rana SM, Razavi H, Reilly RQ, Remuzzi G, Richardus JH, Ronfani L, Roy N, Sabin N, Saeedi MY, Sahraian MA, Samonte GM, Sawhney M, Schneider IJ, Schwebel DC, Seedat S, Sepanlou SG, Servan-Mori EE, Sheikhbahaei S, Shibuya K, Shin HH, Shiue I, Shivakoti R, Sigfusdottir ID, Silberberg DH, Silva AP, Simard EP, Singh JA, Skirbekk V, Sliwa K, Soneji S, Soshnikov SS, Sreeramareddy CT, Stathopoulou VK, Stroumpoulis K, Swaminathan S, Sykes BL, Tabb KM, Talongwa RT, Tenkorang EY, Terkawi AS, Thomson AJ, Thorne-Lyman AL, Towbin JA, Traebert J, Tran BX, Dimbuene ZT, Tsilimbaris M, Uchendu US, Ukwaja KN, Uzun SB, Vallely AJ, Vasankari TJ, Venketasubramanian N, Violante FS, Vlassov VV, Vollset SE, Waller S, Wallin MT, Wang L, Wang X, Wang Y, Weichenthal S, Weiderpass E, Weintraub RG, Westerman R, White RA, Wilkinson JD, Williams TN, Woldeyohannes SM, Wong JQ, Xu G, et al. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014 Sep 13; 384(9947):1005-70. PMID: 25059949.
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Garcia MN, Hotez PJ, Murray KO. Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States. Parasit Vectors. 2014 Jul 04; 7:311. PMID: 24996479.
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Hotez PJ. "Vaccine diplomacy": historical perspectives and future directions. PLoS Negl Trop Dis. 2014 Jun; 8(6):e2808. PMID: 24968231.
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Hotez PJ, Bottazzi ME, Tseng CT, Zhan B, Lustigman S, Du L, Jiang S. Calling for rapid development of a safe and effective MERS vaccine. Microbes Infect. 2014 Jul; 16(7):529-31. PMID: 24931059.
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Hess JA, Zhan B, Bonne-Année S, Deckman JM, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model. Int J Parasitol. 2014 Aug; 44(9):637-46. PMID: 24907553.
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Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK, Gindin M, Hotez PJ, Valenzuela JG, Mohanty B, Swarbrick JD, Wulff H, Iadonato SP, Gutman GA, Beeton C, Pennington MW, Norton RS, Chandy KG. Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. FASEB J. 2014 Sep; 28(9):3952-64. PMID: 24891519.
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Whitham M, Hotez P. In reply. Obstet Gynecol. 2014 Jun; 123(6):1354. PMID: 24848902.
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Hotez PJ. Ten global "hotspots" for the neglected tropical diseases. PLoS Negl Trop Dis. 2014; 8(5):e2496. PMID: 24873825.
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Hotez PJ, Woc-Colburn L, Bottazzi ME. Neglected tropical diseases in Central America and Panama: review of their prevalence, populations at risk and impact on regional development. Int J Parasitol. 2014 Aug; 44(9):597-603. PMID: 24846528.
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Hotez PJ, Murray KO, Buekens P. The Gulf Coast: a new American underbelly of tropical diseases and poverty. PLoS Negl Trop Dis. 2014 May; 8(5):e2760. PMID: 24830815.
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Webster JP, Molyneux DH, Hotez PJ, Fenwick A. The contribution of mass drug administration to global health: past, present and future. Philos Trans R Soc Lond B Biol Sci. 2014; 369(1645):20130434. PMID: 24821920.
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Parise ME, Hotez PJ, Slutsker L. Neglected parasitic infections in the United States: needs and opportunities. Am J Trop Med Hyg. 2014 May; 90(5):783-785. PMID: 24808243.
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Hotez PJ, Velasquez RM, Wolf JE. Neglected tropical skin diseases: their global elimination through integrated mass drug administration? JAMA Dermatol. 2014 May; 150(5):481-2. PMID: 24671756.
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Güngör K, Hotez PJ, Özdemir V, Aynacioglu S. Glaucomics: a call for systems diagnostics for 21(st) century ophthalmology and personalized visual health. OMICS. 2014 May; 18(5):275-9. PMID: 24730382.
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Hotez PJ. Could nitazoxanide be added to other essential medicines for integrated neglected tropical disease control and elimination? PLoS Negl Trop Dis. 2014 Mar; 8(3):e2758. PMID: 24675990.
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Tan M, Kusriastuti R, Savioli L, Hotez PJ. Indonesia: an emerging market economy beset by neglected tropical diseases (NTDs). PLoS Negl Trop Dis. 2014 Feb; 8(2):e2449. PMID: 24587452.
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Hotez PJ. Aboriginal populations and their neglected tropical diseases. PLoS Negl Trop Dis. 2014; 8(1):e2286. PMID: 24498442.
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Tang YT, Gao X, Rosa BA, Abubucker S, Hallsworth-Pepin K, Martin J, Tyagi R, Heizer E, Zhang X, Bhonagiri-Palsikar V, Minx P, Warren WC, Wang Q, Zhan B, Hotez PJ, Sternberg PW, Dougall A, Gaze ST, Mulvenna J, Sotillo J, Ranganathan S, Rabelo EM, Wilson RW, Felgner PL, Bethony J, Hawdon JM, Gasser RB, Loukas A, Mitreva M. Genome of the human hookworm Necator americanus. Nat Genet. 2014 Mar; 46(3):261-269. PMID: 24441737.
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Hotez P. Tropical Medicine in the Horse Latitudes. Curr Trop Med Rep. 2014; 1(1):3-5. PMID: 32226713.
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Zhan B, Beaumier CM, Briggs N, Jones KM, Keegan BP, Bottazzi ME, Hotez PJ. Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections. Expert Rev Vaccines. 2014 Mar; 13(3):321-31. PMID: 24392641.
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Özdemir V, Kolker E, Hotez PJ, Mohin S, Prainsack B, Wynne B, Vayena E, Coskun Y, Dereli T, Huzair F, Borda-Rodriguez A, Bragazzi NL, Faris J, Ramesar R, Wonkam A, Dandara C, Nair B, Llerena A, Kiliç K, Jain R, Reddy PJ, Gollapalli K, Srivastava S, Kickbusch I. Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy. OMICS. 2014 Jan; 18(1):1-9. PMID: 24456464.
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Hotez P, Whitham M. Helminth infections: a new global women's health agenda. Obstet Gynecol. 2014 Jan; 123(1):155-60. PMID: 24463676.
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McCarty TR, Turkeltaub JA, Hotez PJ. Global progress towards eliminating gastrointestinal helminth infections. Curr Opin Gastroenterol. 2014 Jan; 30(1):18-24. PMID: 24241244.
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Curti E, Seid CA, Hudspeth E, Center L, Rezende W, Pollet J, Kwityn C, Hammond M, Matsunami RK, Engler DA, Hotez PJ, Elena Bottazzi M. Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Hum Vaccin Immunother. 2014; 10(7):1914-25. PMID: 25424799.
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Preidis GA, Keaton MA, Campeau PM, Bessard BC, Conner ME, Hotez PJ. The undernourished neonatal mouse metabolome reveals evidence of liver and biliary dysfunction, inflammation, and oxidative stress. J Nutr. 2014 Mar; 144(3):273-81. PMID: 24381221.
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Chen WH, Du L, Chag SM, Ma C, Tricoche N, Tao X, Seid CA, Hudspeth EM, Lustigman S, Tseng CT, Bottazzi ME, Hotez PJ, Zhan B, Jiang S. Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate. Hum Vaccin Immunother. 2014; 10(3):648-58. PMID: 24355931.
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Beaumier CM, Gomez-Rubio AM, Hotez PJ, Weina PJ. United States military tropical medicine: extraordinary legacy, uncertain future. PLoS Negl Trop Dis. 2013; 7(12):e2448. PMID: 24386494.
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Keenan JD, Hotez PJ, Amza A, Stoller NE, Gaynor BD, Porco TC, Lietman TM. Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. PLoS Negl Trop Dis. 2013; 7(12):e2562. PMID: 24340111.
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Hotez PJ. NTDs V.2.0: "blue marble health"--neglected tropical disease control and elimination in a shifting health policy landscape. PLoS Negl Trop Dis. 2013 Nov; 7(11):e2570. PMID: 24278496.
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Hotez PJ, Dumonteil E, Betancourt Cravioto M, Bottazzi ME, Tapia-Conyer R, Meymandi S, Karunakara U, Ribeiro I, Cohen RM, Pecoul B. An unfolding tragedy of Chagas disease in North America. PLoS Negl Trop Dis. 2013; 7(10):e2300. PMID: 24205411.
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Siller M, Reyes N, Hotez E, Hutman T, Sigman M. Longitudinal change in the use of services in autism spectrum disorder: understanding the role of child characteristics, family demographics, and parent cognitions. Autism. 2014 May; 18(4):433-46. PMID: 24108191.
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Hotez P, Singh SK, Zhou XN. Advancing Sino-Indian cooperation to combat tropical diseases. PLoS Negl Trop Dis. 2013; 7(9):e2204. PMID: 24086775.
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Curti E, Kwityn C, Zhan B, Gillespie P, Brelsford J, Deumic V, Plieskatt J, Rezende WC, Tsao E, Kalampanayil B, Hotez PJ, Bottazzi ME. Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis. Hum Vaccin Immunother. 2013 Nov; 9(11):2342-50. PMID: 23899507.
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Rimoin AW, Hotez PJ. NTDs in the heart of darkness: the Democratic Republic of Congo's unknown burden of neglected tropical diseases. PLoS Negl Trop Dis. 2013; 7(7):e2118. PMID: 23936557.
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Cheng W, Curti E, Rezende WC, Kwityn C, Zhan B, Gillespie P, Plieskatt J, Joshi SB, Volkin DB, Hotez PJ, Middaugh CR, Bottazzi ME. Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis. Hum Vaccin Immunother. 2013 Nov; 9(11):2351-61. PMID: 23880663.
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Andrus J, Bottazzi ME, Chow J, Goraleski KA, Fisher-Hoch SP, Lambuth JK, Lee BY, Margolis HS, McCormick JB, Melby P, Murray KO, Rico-Hesse R, Valenzuela JG, Hotez PJ. Ears of the Armadillo: Global Health Research and Neglected Diseases in Texas. PLoS Negl Trop Dis. 2013 Jun; 7(6):e2021. PMID: 23826397.
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Barry MA, Simon GG, Mistry N, Hotez PJ. Global trends in neglected tropical disease control and elimination: impact on child health. Arch Dis Child. 2013 Aug; 98(8):635-41. PMID: 23793132.
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Hotez PJ, Diemert D, Bacon KM, Beaumier C, Bethony JM, Bottazzi ME, Brooker S, Couto AR, Freire Mda S, Homma A, Lee BY, Loukas A, Loblack M, Morel CM, Oliveira RC, Russell PK. The Human Hookworm Vaccine. Vaccine. 2013 Apr 18; 31 Suppl 2:B227-32. PMID: 23598487.
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Beaumier CM, Gillespie PM, Hotez PJ, Bottazzi ME. New vaccines for neglected parasitic diseases and dengue. Transl Res. 2013 Sep; 162(3):144-55. PMID: 23578479.
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Özdemir V, Badr KF, Dove ES, Endrenyi L, Geraci CJ, Hotez PJ, Milius D, Neves-Pereira M, Pang T, Rotimi CN, Sabra R, Sarkissian CN, Srivastava S, Tims H, Zgheib NK, Kickbusch I. Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy. OMICS. 2013 Apr; 17(4):161-72. PMID: 23574338.
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Brindley PJ, Hotez PJ. Break Out: urogenital schistosomiasis and Schistosoma haematobium infection in the post-genomic era. PLoS Negl Trop Dis. 2013; 7(3):e1961. PMID: 23556007.
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Hotez PJ, Papageorgiou TD. A new European neglected diseases center for Greece? PLoS Negl Trop Dis. 2013; 7(2):e1757. PMID: 23469292.
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Lee BY, Bacon KM, Bottazzi ME, Hotez PJ. Global economic burden of Chagas disease: a computational simulation model. Lancet Infect Dis. 2013 Apr; 13(4):342-8. PMID: 23395248.
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Sanghvi MM, Hotez PJ, Fenwick A. Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C Co-infections in Egypt. Liver Int. 2013 Feb; 33(2):165-8. PMID: 23295048.
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Kline K, McCarthy JS, Pearson M, Loukas A, Hotez PJ. Neglected tropical diseases of Oceania: review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis. 2013; 7(1):e1755. PMID: 23383349.
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Barry MA, Weatherhead JE, Hotez PJ, Woc-Colburn L. Childhood parasitic infections endemic to the United States. Pediatr Clin North Am. 2013 Apr; 60(2):471-85. PMID: 23481112.
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Hotez PJ, Dumonteil E, Heffernan MJ, Bottazzi ME. Innovation for the 'bottom 100 million': eliminating neglected tropical diseases in the Americas. Adv Exp Med Biol. 2013; 764:1-12. PMID: 23654053.
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Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black JA, Blencowe H, Blore JD, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha TS, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke CM, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter CE, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng AT, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Des Jarlais DC, Dharmaratne SD, Dherani M, Diaz-Torne C, Dolk H, Dorsey ER, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali SE, Erskine H, Erwin PJ, Espindola P, Ewoigbokhan SE, Farzadfar F, Feigin V, Felson DT, Ferrari A, Ferri CP, Fèvre EM, Finucane MM, Flaxman S, Flood L, Foreman K, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabbe BJ, Gabriel SE, Gakidou E, Ganatra HA, Garcia B, Gaspari F, Gillum RF, Gmel G, Gosselin R, Grainger R, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa YA, Hall W, Haring D, Haro JM, Harrison JE, Havmoeller R, Hay RJ, Higashi H, Hill C, Hoen B, Hoffman H, Hotez PJ, Hoy D, Huang JJ, Ibeanusi SE, Jacobsen KH, James SL, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas JB, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo JP, King CH, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lalloo R, Laslett LL, Lathlean T, Leasher JL, Lee YY, Leigh J, Lim SS, Limb E, Lin JK, Lipnick M, Lipshultz SE, Liu W, Loane M, Ohno SL, Lyons R, Ma J, Mabweijano J, MacIntyre MF, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis DJ, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGill N, McGrath J, Medina-Mora ME, Meltzer M, Mensah GA, Merriman TR, Meyer AC, Miglioli V, Miller M, Miller TR, Mitchell PB, Mocumbi AO, Moffitt TE, Mokdad AA, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch ME, Mwaniki MK, Naidoo K, Nair MN, Naldi L, Narayan KM, Nelson PK, Nelson RG, Nevitt MC, Newton CR, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer SB, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian JD, Rivero AP, Patten SB, Pearce N, Padilla RP, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips MR, Pierce K, Pion S, Polanczyk GV, Polinder S, Pope CA, Popova S, Porrini E, Pourmalek F, Prince M, Pullan RL, Ramaiah KD, Ranganathan D, Razavi H, Regan M, Rehm JT, Rein DB, Remuzzi G, Richardson K, Rivara FP, Roberts T, Robinson C, De Leòn FR, Ronfani L, Room R, Rosenfeld LC, Rushton L, Sacco RL, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel DC, Scott JG, Segui-Gomez M, Shahraz S, Shepard DS, Shin H, Shivakoti R, Singh D, Singh GM, Singh JA, Singleton J, Sleet DA, Sliwa K, Smith E, Smith JL, Stapelberg NJ, Steer A, Steiner T, Stolk WA, Stovner LJ, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor HR, Taylor JA, Taylor WJ, Thomas B, Thomson WM, Thurston GD, Tleyjeh IM, Tonelli M, Towbin JA, Truelsen T, Tsilimbaris MK, Ubeda C, Undurraga EA, van der Werf MJ, van Os J, Vavilala MS, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall DJ, Weinstock MA, Weintraub R, Weisskopf MG, Weissman MM, White RA, Whiteford H, Wiersma ST, Wilkinson JD, Williams HC, Williams SR, Witt E, Wolfe F, Woolf AD, Wulf S, Yeh PH, Zaidi AK, Zheng ZJ, Zonies D, Lopez AD, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012 Dec 15; 380(9859):2163-96. PMID: 23245607.
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Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black JA, Blencowe H, Blore JD, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha TS, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke CM, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter CE, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng AT, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Des Jarlais DC, Dharmaratne SD, Dherani M, Diaz-Torne C, Dolk H, Dorsey ER, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali SE, Erskine H, Erwin PJ, Espindola P, Ewoigbokhan SE, Farzadfar F, Feigin V, Felson DT, Ferrari A, Ferri CP, Fèvre EM, Finucane MM, Flaxman S, Flood L, Foreman K, Forouzanfar MH, Fowkes FG, Fransen M, Freeman MK, Gabbe BJ, Gabriel SE, Gakidou E, Ganatra HA, Garcia B, Gaspari F, Gillum RF, Gmel G, Gonzalez-Medina D, Gosselin R, Grainger R, Grant B, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa YA, Hall W, Haring D, Haro JM, Harrison JE, Havmoeller R, Hay RJ, Higashi H, Hill C, Hoen B, Hoffman H, Hotez PJ, Hoy D, Huang JJ, Ibeanusi SE, Jacobsen KH, James SL, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas JB, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo JP, King CH, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Laden F, Lalloo R, Laslett LL, Lathlean T, Leasher JL, Lee YY, Leigh J, Levinson D, Lim SS, Limb E, Lin JK, Lipnick M, Lipshultz SE, Liu W, Loane M, Ohno SL, Lyons R, Mabweijano J, MacIntyre MF, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis DJ, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGill N, McGrath J, Medina-Mora ME, Meltzer M, Mensah GA, Merriman TR, Meyer AC, Miglioli V, Miller M, Miller TR, Mitchell PB, Mock C, Mocumbi AO, Moffitt TE, Mokdad AA, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch ME, Mwaniki MK, Naidoo K, Nair MN, Naldi L, Narayan KM, Nelson PK, Nelson RG, Nevitt MC, Newton CR, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer SB, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian JD, Rivero AP, Patten SB, Pearce N, Padilla RP, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips MR, Pierce K, Pion S, Polanczyk GV, Polinder S, Pope CA, Popova S, Porrini E, Pourmalek F, Prince M, Pullan RL, Ramaiah KD, Ranganathan D, Razavi H, Regan M, Rehm JT, Rein DB, Remuzzi G, Richardson K, Rivara FP, Roberts T, Robinson C, De Leòn FR, Ronfani L, Room R, Rosenfeld LC, Rushton L, Sacco RL, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel DC, Scott JG, Segui-Gomez M, Shahraz S, Shepard DS, Shin H, Shivakoti R, Singh D, Singh GM, Singh JA, Singleton J, Sleet DA, Sliwa K, Smith E, Smith JL, Stapelberg NJ, Steer A, Steiner T, Stolk WA, Stovner LJ, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor HR, Taylor JA, Taylor WJ, Thomas B, Thomson WM, Thurston GD, Tleyjeh IM, Tonelli M, Towbin JA, Truelsen T, Tsilimbaris MK, Ubeda C, Undurraga EA, van der Werf MJ, van Os J, Vavilala MS, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall DJ, Weinstock MA, Weintraub R, Weisskopf MG, Weissman MM, White RA, Whiteford H, Wiebe N, Wiersma ST, Wilkinson JD, Williams HC, Williams SR, Witt E, Wolfe F, Woolf AD, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012 Dec 15; 380(9859):2197-223. PMID: 23245608.
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Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De León FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, Memish ZA. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012 Dec 15; 380(9859):2095-128. PMID: 23245604.
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Jiang S, Bottazzi ME, Du L, Lustigman S, Tseng CT, Curti E, Jones K, Zhan B, Hotez PJ. Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome. Expert Rev Vaccines. 2012 Dec; 11(12):1405-13. PMID: 23252385.
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Hotez PJ. Engaging a rising China through neglected tropical diseases. PLoS Negl Trop Dis. 2012; 6(11):e1599. PMID: 23209845.
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Bacon KM, Hotez PJ, Kruchten SD, Kamhawi S, Bottazzi ME, Valenzuela JG, Lee BY. The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas. Vaccine. 2013 Jan 07; 31(3):480-6. PMID: 23176979.
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Hotez PJ, Aksoy S. Now we are six. PLoS Negl Trop Dis. 2012; 6(10):e1862. PMID: 23145194.
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Hotez PJ. Fighting neglected tropical diseases in the southern United States. BMJ. 2012 Sep 13; 345:e6112. PMID: 22977143.
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Dumonteil E, Bottazzi ME, Zhan B, Heffernan MJ, Jones K, Valenzuela JG, Kamhawi S, Ortega J, de Leon Rosales SP, Lee BY, Bacon KM, Fleischer B, Slingsby BT, Cravioto MB, Tapia-Conyer R, Hotez PJ. Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects. Expert Rev Vaccines. 2012 Sep; 11(9):1043-55. PMID: 23151163.
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Lee BY, Bacon KM, Wateska AR, Bottazzi ME, Dumonteil E, Hotez PJ. Modeling the economic value of a Chagas' disease therapeutic vaccine. Hum Vaccin Immunother. 2012 Sep; 8(9):1293-301. PMID: 22894964.
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Hotez PJ, Asojo OA, Adesina AM. Nigeria: "Ground Zero" for the high prevalence neglected tropical diseases. PLoS Negl Trop Dis. 2012; 6(7):e1600. PMID: 22860138.
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Hotez PJ. The Four Horsemen of the Apocalypse: Tropical Medicine in the Fight against Plague, Death, Famine, and War. Am J Trop Med Hyg. 2012 Jul; 87(1):3-10. PMID: 22764283.
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Pearson MS, Tribolet L, Cantacessi C, Periago MV, Valero MA, Valerio MA, Jariwala AR, Hotez P, Diemert D, Loukas A, Bethony J. Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. J Allergy Clin Immunol. 2012 Jul; 130(1):13-21. PMID: 22742835.
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Moolani Y, Bukhman G, Hotez PJ. Neglected tropical diseases as hidden causes of cardiovascular disease. PLoS Negl Trop Dis. 2012; 6(6):e1499. PMID: 22745835.
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Hotez PJ, Dumonteil E, Woc-Colburn L, Serpa JA, Bezek S, Edwards MS, Hallmark CJ, Musselwhite LW, Flink BJ, Bottazzi ME. Chagas disease: "the new HIV/AIDS of the Americas". PLoS Negl Trop Dis. 2012; 6(5):e1498. PMID: 22666504.
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Diemert DJ, Pinto AG, Freire J, Jariwala A, Santiago H, Hamilton RG, Periago MV, Loukas A, Tribolet L, Mulvenna J, Correa-Oliveira R, Hotez PJ, Bethony JM. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. J Allergy Clin Immunol. 2012 Jul; 130(1):169-76.e6. PMID: 22633322.
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Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME. Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Hum Vaccin Immunother. 2012 Jun; 8(6):765-76. PMID: 22495115.
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Goud GN, Deumic V, Gupta R, Brelsford J, Zhan B, Gillespie P, Plieskatt JL, Tsao EI, Hotez PJ, Bottazzi ME. Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expr Purif. 2012 Jun; 83(2):145-51. PMID: 22503665.
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Hotez PJ, Bottazzi ME, Dumonteil E, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Cravioto MB, Tapia-Conyer R. Texas and Mexico: sharing a legacy of poverty and neglected tropical diseases. PLoS Negl Trop Dis. 2012; 6(3):e1497. PMID: 22479656.
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Pearson MS, Pickering DA, McSorley HJ, Bethony JM, Tribolet L, Dougall AM, Hotez PJ, Loukas A. Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Negl Trop Dis. 2012; 6(3):e1564. PMID: 22428079.
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Hotez PJ, Savioli L, Fenwick A. Neglected tropical diseases of the Middle East and North Africa: review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis. 2012; 6(2):e1475. PMID: 22389729.
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Hotez PJ, Aksoy S. An interfaith dialogue on the neglected tropical diseases. PLoS Negl Trop Dis. 2011 Dec; 5(12):e1240. PMID: 22206020.
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Hotez P. Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases. Vaccine. 2011 Dec 30; 29 Suppl 4:D104-10. PMID: 22188933.
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Hotez PJ, Goraleski KA. Neglected tropical diseases and the 2012 US presidential election. PLoS Negl Trop Dis. 2011 Nov; 5(11):e1431. PMID: 22140593.
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Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM. A history of hookworm vaccine development. Hum Vaccin. 2011 Nov; 7(11):1234-44. PMID: 22064562.
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Lobo DA, Velayudhan R, Chatterjee P, Kohli H, Hotez PJ. The neglected tropical diseases of India and South Asia: review of their prevalence, distribution, and control or elimination. PLoS Negl Trop Dis. 2011 Oct; 5(10):e1222. PMID: 22039553.
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Xue J, Zhan B, Guo J, He N, Qiang HQ, Hotez P, Xiao SH. Acquired hookworm immunity in the golden hamster (Mesocricetus auratus) elicited by living Necator americanus third-stage infective larvae. Exp Parasitol. 2012 Jan; 130(1):6-12. PMID: 22024448.
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Hotez PJ, Alibek K. Central Asia's hidden burden of neglected tropical diseases. PLoS Negl Trop Dis. 2011 Sep; 5(9):e1224. PMID: 21980541.
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Nair SS, Bommana A, Pakala SB, Ohshiro K, Lyon AJ, Suttiprapa S, Periago MV, Laha T, Hotez PJ, Bethony JM, Sripa B, Brindley PJ, Kumar R. Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology. 2011 Oct; 54(4):1388-97. PMID: 21725997.
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Noblick J, Skolnik R, Hotez PJ. Linking global HIV/AIDS treatments with national programs for the control and elimination of the neglected tropical diseases. PLoS Negl Trop Dis. 2011 Jul; 5(7):e1022. PMID: 21814582.
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Hotez PJ, Gurwith M. Europe's neglected infections of poverty. Int J Infect Dis. 2011 Sep; 15(9):e611-9. PMID: 21763173.
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Hotez PJ. Unleashing "civilian power": a new American diplomacy through neglected tropical disease control, elimination, research, and development. PLoS Negl Trop Dis. 2011 Jun; 5(6):e1134. PMID: 21738802.
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Loukas A, Gaze S, Mulvenna JP, Gasser RB, Brindley PJ, Doolan DL, Bethony JM, Jones MK, Gobert GN, Driguez P, McManus DP, Hotez PJ. Vaccinomics for the major blood feeding helminths of humans. OMICS. 2011 Sep; 15(9):567-77. PMID: 21679087.
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Nair SS, Bommana A, Bethony JM, Lyon AJ, Ohshiro K, Pakala SB, Rinaldi G, Keegan B, Suttiprapa S, Periago MV, Hotez PJ, Brindley PJ, Kumar R. The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology. 2011 Jul; 54(1):285-95. PMID: 21488078.
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Hotez PJ, Mistry N, Rubinstein J, Sachs JD. Integrating neglected tropical diseases into AIDS, tuberculosis, and malaria control. N Engl J Med. 2011 Jun 02; 364(22):2086-9. PMID: 21631320.
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Hotez P. A handful of 'antipoverty' vaccines exist for neglected diseases, but the world's poorest billion people need more. Health Aff (Millwood). 2011 Jun; 30(6):1080-7. PMID: 21653960.
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Hotez PJ. New antipoverty drugs, vaccines, and diagnostics: a research agenda for the US President's Global Health Initiative (GHI). PLoS Negl Trop Dis. 2011; 5(5):e1133. PMID: 21655348.
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Hotez PJ. Neglected tropical diseases in the Catholic world. PLoS Negl Trop Dis. 2011 Apr 26; 5(4):e1132. PMID: 21541361.
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Hotez PJ. America's most distressed areas and their neglected infections: the United States Gulf Coast and the District of Columbia. PLoS Negl Trop Dis. 2011 Mar 29; 5(3):e843. PMID: 21468312.
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Alexander N, Cundill B, Sabatelli L, Bethony JM, Diemert D, Hotez P, Smith PG, Rodrigues LC, Brooker S. Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths. Vaccine. 2011 May 09; 29(20):3686-94. PMID: 21435404.
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Jiang D, Zhan B, Mayor RS, Gillespie P, Keegan B, Bottazzi ME, Hotez P. Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum. Mol Biochem Parasitol. 2011 May; 177(1):42-8. PMID: 21251931.
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Bethony JM, Cole RN, Guo X, Kamhawi S, Lightowlers MW, Loukas A, Petri W, Reed S, Valenzuela JG, Hotez PJ. Vaccines to combat the neglected tropical diseases. Immunol Rev. 2011 Jan; 239(1):237-70. PMID: 21198676.
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Jex AR, Lim YA, Bethony JM, Hotez PJ, Young ND, Gasser RB. Soil-transmitted helminths of humans in Southeast Asia--towards integrated control. Adv Parasitol. 2011; 74:231-65. PMID: 21295679.
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Bourhy H, Dautry-Varsat A, Hotez PJ, Salomon J. Rabies, still neglected after 125 years of vaccination. PLoS Negl Trop Dis. 2010 Nov 30; 4(11):e839. PMID: 21152052.
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Waldor MK, Hotez PJ, Clemens JD. A national cholera vaccine stockpile--a new humanitarian and diplomatic resource. N Engl J Med. 2010 Dec 09; 363(24):2279-82. PMID: 21105832.
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Hotez PJ, Bethony JM, Diemert DJ, Pearson M, Loukas A. Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nat Rev Microbiol. 2010 Nov; 8(11):814-26. PMID: 20948553.
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Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM. Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Rev Vaccines. 2010 Oct; 9(10):1219-30. PMID: 20923271.
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Hotez PJ. Neglected tropical disease control in the "post-American world". PLoS Negl Trop Dis. 2010 Aug 31; 4(8). PMID: 20824178.
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Hotez PJ, Engels D, Fenwick A, Savioli L. Africa is desperate for praziquantel. Lancet. 2010 Aug 14; 376(9740):496-8. PMID: 20709217.
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Brooker S, Hotez PJ, Bundy DA. The global atlas of helminth infection: mapping the way forward in neglected tropical disease control. PLoS Negl Trop Dis. 2010 Jul 27; 4(7):e779. PMID: 20668545.
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Sripa B, Bethony JM, Sithithaworn P, Kaewkes S, Mairiang E, Loukas A, Mulvenna J, Laha T, Hotez PJ, Brindley PJ. Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Trop. 2011 Sep; 120 Suppl 1:S158-68. PMID: 20655862.
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Hotez P. A national school of tropical medicine and neglected infections of poverty for North America. PLoS Negl Trop Dis. 2010 Jun 29; 4(6):e735. PMID: 20614018.
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Hotez PJ, Pecoul B. "Manifesto" for advancing the control and elimination of neglected tropical diseases. PLoS Negl Trop Dis. 2010 May 25; 4(5):e718. PMID: 20520793.
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Spiegel JM, Dharamsi S, Wasan KM, Yassi A, Singer B, Hotez PJ, Hanson C, Bundy DA. Which new approaches to tackling neglected tropical diseases show promise? PLoS Med. 2010 May 18; 7(5):e1000255. PMID: 20502599.
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Pearson MS, Pickering DA, Tribolet L, Cooper L, Mulvenna J, Oliveira LM, Bethony JM, Hotez PJ, Loukas A. Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. J Infect Dis. 2010 May 15; 201(10):1561-9. PMID: 20367477.
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Hotez P, Stillwaggon E, McDonald M, Todman L, DiGrazia L. National summit on neglected infections of poverty in the United States. Emerg Infect Dis. 2010 May; 16(5):e1. PMID: 20409362.
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Hotez PJ. Nuclear weapons and neglected diseases: the "ten-thousand-to-one gap". PLoS Negl Trop Dis. 2010 Apr 27; 4(4):e680. PMID: 20436916.
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Hotez PJ. Peace through vaccine diplomacy. Science. 2010 Mar 12; 327(5971):1301. PMID: 20223952.
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Kishore SP, Tavera G, Hotez PJ. The global health crisis and our nation's research universities. PLoS Negl Trop Dis. 2010 Feb 23; 4(2):e635. PMID: 20186327.
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Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, Ranjit N, Lustigman S, Oksov Y, Hotez P. Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infect Immun. 2010 Apr; 78(4):1552-63. PMID: 20145100.
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Asojo OA, Goud GN, Zhan B, Ordonez K, Sedlacek M, Homma K, Deumic V, Gupta R, Brelsford J, Price MK, Ngamelue MN, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-SAA-2 from the human hookworm parasite Necator americanus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 01; 66(Pt 2):172-6. PMID: 20124715.
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Hotez PJ. Neglected infections of poverty among the indigenous peoples of the arctic. PLoS Negl Trop Dis. 2010 Jan 26; 4(1):e606. PMID: 20126272.
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Hotez PJ, Ehrenberg JP. Escalating the global fight against neglected tropical diseases through interventions in the Asia Pacific region. Adv Parasitol. 2010; 72:31-53. PMID: 20624527.
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Hotez PJ. A plan to defeat neglected tropical diseases. Sci Am. 2010 Jan; 302(1):90-4, 96. PMID: 20063641.
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Hotez PJ. Empowering women and improving female reproductive health through control of neglected tropical diseases. PLoS Negl Trop Dis. 2009 Nov 24; 3(11):e559. PMID: 19936248.
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Hotez P. Neglected diseases amid wealth in the United States and Europe. Health Aff (Millwood). 2009 Nov-Dec; 28(6):1720-5. PMID: 19887412.
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Musgrove P, Hotez PJ. Turning neglected tropical diseases into forgotten maladies. Health Aff (Millwood). 2009 Nov-Dec; 28(6):1691-706. PMID: 19887410.
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Hotez PJ. The neglected tropical diseases and their devastating health and economic impact on the member nations of the Organisation of the Islamic Conference. PLoS Negl Trop Dis. 2009 Oct 27; 3(10):e539. PMID: 19859530.
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Hotez PJ, Fenwick A. Schistosomiasis in Africa: an emerging tragedy in our new global health decade. PLoS Negl Trop Dis. 2009 Sep 29; 3(9):e485. PMID: 19787054.
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Hotez PJ. A constitutional amendment for deworming. PLoS Negl Trop Dis. 2009 Aug 25; 3(8):e454. PMID: 19707577.
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Hotez PJ, Kamath A. Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden. PLoS Negl Trop Dis. 2009 Aug 25; 3(8):e412. PMID: 19707588.
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Franco-Paredes C, Bottazzi ME, Hotez PJ. The unfinished public health agenda of chagas disease in the era of globalization. PLoS Negl Trop Dis. 2009 Jul 07; 3(7):e470. PMID: 19582139.
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Stoever K, Molyneux D, Hotez P, Fenwick A. HIV/AIDS, schistosomiasis, and girls. Lancet. 2009 Jun 13; 373(9680):2025-6. PMID: 19524778.
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Hotez PJ, Fenwick A, Kjetland EF. Africa's 32 cents solution for HIV/AIDS. PLoS Negl Trop Dis. 2009 May 26; 3(5):e430. PMID: 19479041.
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Hotez PJ, Fenwick A, Savioli L, Molyneux DH. Rescuing the bottom billion through control of neglected tropical diseases. Lancet. 2009 May 02; 373(9674):1570-5. PMID: 19410718.
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Hotez PJ. One world health: neglected tropical diseases in a flat world. PLoS Negl Trop Dis. 2009; 3(4):e405. PMID: 19399165.
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Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, Jones K, Keegan B, Hotez PJ, Loukas A. An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB J. 2009 Sep; 23(9):3007-19. PMID: 19380510.
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Hotez PJ, Wilkins PP. Toxocariasis: America's most common neglected infection of poverty and a helminthiasis of global importance? PLoS Negl Trop Dis. 2009; 3(3):e400. PMID: 19333373.
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Hotez PJ, Brown AS. Neglected tropical disease vaccines. Biologicals. 2009 Jun; 37(3):160-4. PMID: 19278869.
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Ranjit N, Zhan B, Hamilton B, Stenzel D, Lowther J, Pearson M, Gorman J, Hotez P, Loukas A. Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. J Infect Dis. 2009 Mar 15; 199(6):904-12. PMID: 19434933.
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Hotez PJ, Thompson TG. Waging peace through neglected tropical disease control: a US foreign policy for the bottom billion. PLoS Negl Trop Dis. 2009; 3(1):e346. PMID: 19172176.
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Molyneux DH, Hotez PJ, Fenwick A, Newman RD, Greenwood B, Sachs J. Neglected tropical diseases and the Global Fund. Lancet. 2009 Jan 24; 373(9660):296-7. PMID: 19167564.
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Andrus JK, de Quadros C, Matus CR, Luciani S, Hotez P. New vaccines for developing countries: will it be feast or famine? Am J Law Med. 2009; 35(2-3):311-22. PMID: 19697751.
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Hotez PJ. Tropical diseases research: thirty years and counting. PLoS Negl Trop Dis. 2008; 2(11):e329. PMID: 19030224.
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Hotez PJ, Daar AS. The CNCDs and the NTDs: blurring the lines dividing noncommunicable and communicable chronic diseases. PLoS Negl Trop Dis. 2008; 2(10):e312. PMID: 18958154.
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Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis. 2008 Sep 24; 2(9):e300. PMID: 18820747.
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Brooker S, Hotez PJ, Bundy DA. Hookworm-related anaemia among pregnant women: a systematic review. PLoS Negl Trop Dis. 2008 Sep 17; 2(9):e291. PMID: 18820740.
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Zhan B, Gupta R, Wong SP, Bier S, Jiang D, Goud G, Hotez P. Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum. Mol Biochem Parasitol. 2008 Dec; 162(2):142-8. PMID: 18804124.
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Hotez PJ. Training the next generation of global health scientists: a school of appropriate technology for global health. PLoS Negl Trop Dis. 2008; 2(8):e279. PMID: 18846232.
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Hotez PJ, Bethony JM, Oliveira SC, Brindley PJ, Loukas A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Rev Vaccines. 2008 Aug; 7(6):745-52. PMID: 18665774.
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Hotez PJ, Molyneux DH. Tropical anemia: one of Africa's great killers and a rationale for linking malaria and neglected tropical disease control to achieve a common goal. PLoS Negl Trop Dis. 2008 Jul 30; 2(7):e270. PMID: 18665256.
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Hotez PJ. Neglected infections of poverty in the United States of America. PLoS Negl Trop Dis. 2008 Jun 25; 2(6):e256. PMID: 18575621.
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Hotez PJ. Holidays in the sun and the Caribbean's forgotten burden of neglected tropical diseases. PLoS Negl Trop Dis. 2008 May 28; 2(5):e239. PMID: 18509471.
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Hotez PJ. Stigma: the stealth weapon of the NTD. PLoS Negl Trop Dis. 2008 Apr 30; 2(4):e230. PMID: 18446206.
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Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Mol Biochem Parasitol. 2008 Aug; 160(2):90-9. PMID: 18501979.
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Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. J Clin Invest. 2008 Apr; 118(4):1311-21. PMID: 18382743.
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Hotez PJ, Molyneux DH, Fenwick A, Savioli L, Takeuchi T. A Global Fund to Fight Neglected Tropical Diseases: is the G8 Hokkaido Toyako 2008 Summit ready? PLoS Negl Trop Dis. 2008 Mar 26; 2(3):e220. PMID: 18365038.
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Bethony JM, Simon G, Diemert DJ, Parenti D, Desrosiers A, Schuck S, Fujiwara R, Santiago H, Hotez PJ. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 2008 May 02; 26(19):2408-17. PMID: 18396361.
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Hotez PJ. Reinventing Guantanamo: from detainee facility to Center for Research on Neglected Diseases of Poverty in the Americas. PLoS Negl Trop Dis. 2008 Feb 27; 2(2):e201. PMID: 18301728.
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Hotez PJ. The giant anteater in the room: Brazil's neglected tropical diseases problem. PLoS Negl Trop Dis. 2008 Jan 30; 2(1):e177. PMID: 18327292.
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Diemert DJ, Bethony JM, Hotez PJ. Hookworm vaccines. Clin Infect Dis. 2008 Jan 15; 46(2):282-8. PMID: 18171264.
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Hotez PJ. Neglected diseases and poverty in "The Other America": the greatest health disparity in the United States? PLoS Negl Trop Dis. 2007 Dec 26; 1(3):e149. PMID: 18160982.
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Brooker S, Akhwale W, Pullan R, Estambale B, Clarke SE, Snow RW, Hotez PJ. Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control. Am J Trop Med Hyg. 2007 Dec; 77(6 Suppl):88-98. PMID: 18165479.
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Hotez P. Measuring neglect. PLoS Negl Trop Dis. 2007 Nov 28; 1(2):e118. PMID: 18060078.
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Hotez P. A new voice for the poor. PLoS Negl Trop Dis. 2007 Oct 31; 1(1):e77. PMID: 17989790.
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Hotez P, Raff S, Fenwick A, Richards F, Molyneux DH. Recent progress in integrated neglected tropical disease control. Trends Parasitol. 2007 Nov; 23(11):511-4. PMID: 17951109.
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Hotez P. Hookworm and poverty. Ann N Y Acad Sci. 2008; 1136:38-44. PMID: 17954674.
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Hotez PJ, Molyneux DH, Fenwick A, Kumaresan J, Sachs SE, Sachs JD, Savioli L. Control of neglected tropical diseases. N Engl J Med. 2007 Sep 06; 357(10):1018-27. PMID: 17804846.
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Alexander N, Bethony J, Corrêa-Oliveira R, Rodrigues LC, Hotez P, Brooker S. Repeatability of paired counts. Stat Med. 2007 Aug 30; 26(19):3566-77. PMID: 17091531.
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Yamey G, Hotez P. Neglected tropical diseases. BMJ. 2007 Aug 11; 335(7614):269-70. PMID: 17690342.
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Asojo OA, Homma K, Sedlacek M, Ngamelue M, Goud GN, Zhan B, Deumic V, Asojo O, Hotez PJ. X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. BMC Struct Biol. 2007 Jun 26; 7:42. PMID: 17594497.
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Hotez PJ. Control of onchocerciasis--the next generation. Lancet. 2007 Jun 16; 369(9578):1979-1980. PMID: 17574078.
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Xiao S, Zhan B, Xue J, Goud GN, Loukas A, Liu Y, Williamson A, Liu S, Deumic V, Hotez P. The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Exp Parasitol. 2008 Jan; 118(1):32-40. PMID: 17645877.
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Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM. Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16. Clin Vaccine Immunol. 2007 Mar; 14(3):281-7. PMID: 17267592.
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Feng J, Zhan B, Liu Y, Liu S, Williamson A, Goud G, Loukas A, Hotez P. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Mol Biochem Parasitol. 2007 Apr; 152(2):132-8. PMID: 17280728.
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Inan M, Fanders SA, Zhang W, Hotez PJ, Zhan B, Meagher MM. Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods Mol Biol. 2007; 389:65-76. PMID: 17951635.
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Hotez PJ, Molyneux DH, Stillwaggon E, Bentwich Z, Kumaresan J. Neglected tropical diseases and HIV/AIDS. Lancet. 2006 Nov 25; 368(9550):1865-6. PMID: 17126708.
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Brooker S, Clements AC, Hotez PJ, Hay SI, Tatem AJ, Bundy DA, Snow RW. The co-distribution of Plasmodium falciparum and hookworm among African schoolchildren. Malar J. 2006 Nov 03; 5:99. PMID: 17083720.
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Loukas A, Bethony J, Brooker S, Hotez P. Hookworm vaccines: past, present, and future. Lancet Infect Dis. 2006 Nov; 6(11):733-41. PMID: 17067922.
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Brooker S, Jardim-Botelho A, Quinnell RJ, Geiger SM, Caldas IR, Fleming F, Hotez PJ, Correa-Oliveira R, Rodrigues LC, Bethony JM. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg. 2007 Feb; 101(2):146-54. PMID: 17027054.
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Jian X, Jun-Min Y, Hai-Chou X, Hui-Qing Q, Hai-Nan R, Hotez P, Bin Z, Shu-Hua X. Protective immunity elicited by ultraviolet-irradiated third-stage infective hookworm (Necator americanus and Ancylostoma caninum) larvae in mice and hamsters. Southeast Asian J Trop Med Public Health. 2006 Sep; 37(5):885-95. PMID: 17333729.
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Gupta R, Hotez P. Rethinking global health training in North America. MedGenMed. 2006 Aug 24; 8(3):47. PMID: 17406177.
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Brooker S, Alexander N, Geiger S, Moyeed RA, Stander J, Fleming F, Hotez PJ, Correa-Oliveira R, Bethony J. Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil. Int J Parasitol. 2006 Sep; 36(10-11):1143-51. PMID: 16814294.
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Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Diemert D, Loukas A. New technologies for the control of human hookworm infection. Trends Parasitol. 2006 Jul; 22(7):327-31. PMID: 16709466.
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Hotez PJ, Ferris MT. The antipoverty vaccines. Vaccine. 2006 Jul 26; 24(31-32):5787-99. PMID: 16759763.
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Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, Hotez PJ. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 2006 May 06; 367(9521):1521-32. PMID: 16679166.
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Bottazzi ME, Miles AP, Diemert D, Hotez PJ. An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases. Expert Rev Vaccines. 2006 Apr; 5(2):189-98. PMID: 16608419.
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Sachs JD, Hotez PJ. Fighting tropical diseases. Science. 2006 Mar 17; 311(5767):1521. PMID: 16543418.
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Hotez P, Stoever K, Fenwick A, Molyneux D, Savioli L. The Lancet's chronic diseases series. Lancet. 2006 Feb 18; 367(9510):563-4; author reply 564-5. PMID: 16488790.
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Williamson AL, Lustigman S, Oksov Y, Deumic V, Plieskatt J, Mendez S, Zhan B, Bottazzi ME, Hotez PJ, Loukas A. Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration. Infect Immun. 2006 Feb; 74(2):961-7. PMID: 16428741.
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Hotez P, Gupta R, Mahoney R, Poste G. Incorporating appropriate technology into North American schools of public health. Rev Panam Salud Publica. 2006 Feb; 19(2):118-23. PMID: 16551386.
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Fleming FM, Brooker S, Geiger SM, Caldas IR, Correa-Oliveira R, Hotez PJ, Bethony JM. Synergistic associations between hookworm and other helminth species in a rural community in Brazil. Trop Med Int Health. 2006 Jan; 11(1):56-64. PMID: 16398756.
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Hotez P, Ottesen E, Fenwick A, Molyneux D. The neglected tropical diseases: the ancient afflictions of stigma and poverty and the prospects for their control and elimination. Adv Exp Med Biol. 2006; 582:23-33. PMID: 16802616.
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Hotez PJ, Molyneux DH, Fenwick A, Ottesen E, Ehrlich Sachs S, Sachs JD. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med. 2006 Jan; 3(5):e102. PMID: 16435908.
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Ghosh K, Wu W, Antoine AD, Bottazzi ME, Valenzuela JG, Hotez PJ, Mendez S. The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. J Infect Dis. 2006 Jan 01; 193(1):155-62. PMID: 16323144.
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Molyneux DH, Hotez PJ, Fenwick A. "Rapid-impact interventions": how a policy of integrated control for Africa's neglected tropical diseases could benefit the poor. PLoS Med. 2005 Nov; 2(11):e336. PMID: 16212468.
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Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. PLoS Med. 2005 Oct; 2(10):e295. PMID: 16231975.
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Zhan B, Liu S, Perally S, Xue J, Fujiwara R, Brophy P, Xiao S, Liu Y, Feng J, Williamson A, Wang Y, Bueno LL, Mendez S, Goud G, Bethony JM, Hawdon JM, Loukas A, Jones K, Hotez PJ. Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infect Immun. 2005 Oct; 73(10):6903-11. PMID: 16177370.
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Xue J, Hui-Qing Q, Jun-Ming Y, Fujiwara R, Zhan B, Hotez P, Shu-Hua X. Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Exp Parasitol. 2005 Dec; 111(4):219-23. PMID: 16198341.
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Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, Bethony JM, Loukas A, Roy M, Hotez PJ. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 2005 Sep 15; 23(39):4754-64. PMID: 16054275.
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Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM. Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs. Vaccine. 2006 Jan 23; 24(4):501-9. PMID: 16140437.
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Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J. 2005 Oct; 19(12):1743-5. PMID: 16037096.
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Morel CM, Acharya T, Broun D, Dangi A, Elias C, Ganguly NK, Gardner CA, Gupta RK, Haycock J, Heher AD, Hotez PJ, Kettler HE, Keusch GT, Krattiger AF, Kreutz FT, Lall S, Lee K, Mahoney R, Martinez-Palomo A, Mashelkar RA, Matlin SA, Mzimba M, Oehler J, Ridley RG, Senanayake P, Singer P, Yun M. Health innovation networks to help developing countries address neglected diseases. Science. 2005 Jul 15; 309(5733):401-4. PMID: 16020723.
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Hotez P, Bethony J, Brooker S, Albonico M. Eliminating neglected diseases in Africa. Lancet. 2005 Jun 18-24; 365(9477):2089. PMID: 15964442.
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Mendez S, Valenzuela JG, Wu W, Hotez PJ. Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster. Infect Immun. 2005 Jun; 73(6):3402-7. PMID: 15908367.
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Fujiwara RT, Bethony J, Bueno LL, Wang Y, Ahn SY, Samuel A, Bottazzi ME, Hotez P, Mendez S. Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Hum Vaccin. 2005 May-Jun; 1(3):123-8. PMID: 17012856.
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Mendez S, Zhan B, Goud G, Ghosh K, Dobardzic A, Wu W, Liu S, Deumic V, Dobardzic R, Liu Y, Bethony J, Hotez PJ. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine. 2005 May 02; 23(24):3123-30. PMID: 15837211.
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Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P. Hookworm: "the great infection of mankind". PLoS Med. 2005 Mar; 2(3):e67. PMID: 15783256.
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Asojo OA, Loukas A, Inan M, Barent R, Huang J, Plantz B, Swanson A, Gouthro M, Meagher MM, Hotez PJ. Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 01; 61(Pt 4):391-4. PMID: 16511050.
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Asojo OA, Goud G, Dhar K, Loukas A, Zhan B, Deumic V, Liu S, Borgstahl GE, Hotez PJ. X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J Mol Biol. 2005 Feb 25; 346(3):801-14. PMID: 15713464.
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Hotez PJ, Arora S, Bethony J, Bottazzi ME, Loukas A, Correa-Oliveira R, Brooker S. Helminth infections of children: prospects for control. Adv Exp Med Biol. 2005; 568:135-44. PMID: 16108129.
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Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S. Hookworm infection. N Engl J Med. 2004 Aug 19; 351(8):799-807. PMID: 15317893.
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Hsieh GC, Loukas A, Wahl AM, Bhatia M, Wang Y, Williamson AL, Kehn KW, Maruyama H, Hotez PJ, Leitenberg D, Bethony J, Constant SL. A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. J Immunol. 2004 Aug 15; 173(4):2699-704. PMID: 15294988.
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Hotez PJ. Should we establish a North American school of global health sciences? Am J Med Sci. 2004 Aug; 328(2):71-7. PMID: 15311164.
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Don TA, Jones MK, Smyth D, O'Donoghue P, Hotez P, Loukas A. A pore-forming haemolysin from the hookworm, Ancylostoma caninum. Int J Parasitol. 2004 Aug; 34(9):1029-35. PMID: 15313129.
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Zhan B, Wang Y, Liu Y, Williamson A, Loukas A, Hawdon JM, Xue HC, Xiao SH, Hotez PJ. Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. Int J Parasitol. 2004 Aug; 34(9):1037-45. PMID: 15313130.
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Williamson AL, Lecchi P, Turk BE, Choe Y, Hotez PJ, McKerrow JH, Cantley LC, Sajid M, Craik CS, Loukas A. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J Biol Chem. 2004 Aug 20; 279(34):35950-7. PMID: 15199048.
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Hotez PJ. The National Institutes of Health roadmap and the developing world. J Investig Med. 2004 May; 52(4):246-7. PMID: 15521545.
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Loukas A, Bethony JM, Williamson AL, Goud GN, Mendez S, Zhan B, Hawdon JM, Elena Bottazzi M, Brindley PJ, Hotez PJ. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. J Infect Dis. 2004 May 15; 189(10):1952-61. PMID: 15122534.
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Hotez PJ, Remme JH, Buss P, Alleyne G, Morel C, Breman JG. Combating tropical infectious diseases: report of the Disease Control Priorities in Developing Countries Project. Clin Infect Dis. 2004 Mar 15; 38(6):871-8. PMID: 14999633.
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Goud GN, Zhan B, Ghosh K, Loukas A, Hawdon J, Dobardzic A, Deumic V, Liu S, Dobardzic R, Zook BC, Jin Q, Liu Y, Hoffman L, Chung-Debose S, Patel R, Mendez S, Hotez PJ. Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. J Infect Dis. 2004 Mar 01; 189(5):919-29. PMID: 14976610.
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Brooker S, Bethony J, Hotez PJ. Human hookworm infection in the 21st century. Adv Parasitol. 2004; 58:197-288. PMID: 15603764.
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de Silva NR, Brooker S, Hotez PJ, Montresor A, Engels D, Savioli L. Soil-transmitted helminth infections: updating the global picture. Trends Parasitol. 2003 Dec; 19(12):547-51. PMID: 14642761.
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Jian X, Shu-Hua X, Hui-Qing Q, Sen L, Hotez P, Bing-Gui S, Hai-Chou X, Tie-Hua L, Bin Z. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). II. Morphological development of the adult and its comparison with humans. Exp Parasitol. 2003 Nov-Dec; 105(3-4):192-200. PMID: 14990312.
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Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, Essiet-Gibson I, Chung-Debose S, Xiao S, Knox D, Meagher M, Inan M, Correa-Oliveira R, Vilk P, Shepherd HR, Brandt W, Russell PK. Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. Int J Parasitol. 2003 Sep 30; 33(11):1245-58. PMID: 13678639.
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Williamson AL, Brindley PJ, Knox DP, Hotez PJ, Loukas A. Digestive proteases of blood-feeding nematodes. Trends Parasitol. 2003 Sep; 19(9):417-23. PMID: 12957519.
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Zhan B, Liu Y, Badamchian M, Williamson A, Feng J, Loukas A, Hawdon JM, Hotez PJ. Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. Int J Parasitol. 2003 Aug; 33(9):897-907. PMID: 12906874.
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Hotez PJ, Ashcom J, Zhan B, Bethony J, Loukas A, Hawdon J, Wang Y, Jin Q, Jones KC, Dobardzic A, Dobardzic R, Bolden J, Essiet I, Brandt W, Russell PK, Zook BC, Howard B, Chacon M. Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. J Parasitol. 2003 Aug; 89(4):853-5. PMID: 14533704.
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Hotez PJ. Erosion of William Henry Welch's concept of the hygienic laboratory in our nation's schools of public health and medicine. Public Health Rep. 2003 May-Jun; 118(3):184-6. PMID: 12766211.
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Dalton JP, Brindley PJ, Knox DP, Brady CP, Hotez PJ, Donnelly S, O'Neill SM, Mulcahy G, Loukas A. Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. Int J Parasitol. 2003 May; 33(5-6):621-40. PMID: 12782060.
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Jian X, Sen L, Hui-Qin Q, Hai-Nan R, Tie-Hua L, Hai-Chou X, Hotez PJ, Shu-Hua X. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity. Exp Parasitol. 2003 May-Jun; 104(1-2):62-6. PMID: 12932761.
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Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. J Infect Dis. 2003 Feb 01; 187(3):484-94. PMID: 12552433.
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Basavaraju SV, Basavaraju S, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Mol Biochem Parasitol. 2003 Jan; 126(1):63-71. PMID: 12554085.
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Hotez PJ. Loss of laboratory instruction in American medical schools: erosion of Flexner's view of "scientific medical education.". Am J Med Sci. 2003 Jan; 325(1):10-4. PMID: 12544079.
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Zhu XP, Yang J, Yang YP, Boireau P, Zhan B, Feng JJ, Hotez P. [Prokaryotic expression and characterization of an antigenic gene of adult Trichinella spiralis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2003; 21(1):16-9. PMID: 12884582.
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Bethony J, Chen J, Lin S, Xiao S, Zhan B, Li S, Xue H, Xing F, Humphries D, Yan W, Chen G, Foster V, Hawdon JM, Hotez PJ. Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clin Infect Dis. 2002 Dec 01; 35(11):1336-44. PMID: 12439796.
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Broder S, Hoffman SL, Hotez PJ. Cures for the Third World's problems: the application of genomics to the diseases plaguing the developing world may have huge medical and economic benefits for those countries and might even prevent armed conflict. EMBO Rep. 2002 Sep; 3(9):806-12. PMID: 12223456.
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Hotez PJ, Ashcom J, Bin Z, Bethony J, Williamson A, Hawdon JM, Jianjun F, Dobardzic A, Rizo I, Bolden J, Jin Q, Yan W, Dobardzic R, Chung-Debose S, Crowell M, Datu B, Delaney A, Dragonovski D, Jiang Y, Yueyuan L, Ghosh K, Loukas A, Brandt W, Russell PK, Zook BC. Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine. J Parasitol. 2002 Aug; 88(4):684-90. PMID: 12197114.
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Mingjie W, Shuhua X, Junjie C, Bin L, Cheng F, Weixia S, Hotez P. Albendazole-soybean oil emulsion for the treatment of human cystic echinococcosis: evaluation of bioavailability and bioequivalence. Acta Trop. 2002 Aug; 83(2):177-81. PMID: 12088859.
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Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. FASEB J. 2002 Sep; 16(11):1458-60. PMID: 12205047.
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Zhan B, Hotez PJ, Wang Y, Hawdon JM. A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Mol Biochem Parasitol. 2002 Apr 09; 120(2):291-6. PMID: 11897134.
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Shuhua X, Jiqing Y, Mingjie W, Pieying J, Fanghua G, Junjie C, Wei J, Hotez P. Augmented bioavailability and cysticidal activity of albendazole reformulated in soybean emulsion in mice infected with Echinococcus granulosus or Echinococcus multilocularis. Acta Trop. 2002 Apr; 82(1):77-84. PMID: 11904106.
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Zhan B, Badamchian M, Meihua B, Ashcom J, Feng J, Hawdon J, Shuhua X, Hotez PJ. Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms. Am J Trop Med Hyg. 2002 Mar; 66(3):238-44. PMID: 12139214.
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Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Mol Biochem Parasitol. 2002 Jan; 119(1):107-16. PMID: 11755191.
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Yang Y, Xiau S, Ren H, Wu J, Hotez PJ. Cutaneous and subcutaneous granulomata formation in mice immunized and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Trop. 1998 Jun; 69(3):229-38. PMID: 9638275.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 1998 | 1 | | 2002 | 9 | | 2003 | 13 | | 2004 | 11 | | 2005 | 17 | | 2006 | 18 | | 2007 | 15 | | 2008 | 18 | | 2009 | 19 | | 2010 | 21 | | 2011 | 22 | | 2012 | 21 | | 2013 | 23 | | 2014 | 41 | | 2015 | 28 | | 2016 | 38 | | 2017 | 43 | | 2018 | 34 | | 2019 | 38 | | 2020 | 39 |
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