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CAROLINA JORGEZ

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Urology
Address6621 FANNIN
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Reproductive Medicine
    DivisionCenter for Reproductive Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chahdi A, Jorgez C, Seth A. Regulation of androgen receptor stability by the ?1 Pix/STUB1 complex. FASEB J. 2024 02; 38(2):e23408. PMID: 38197270.
      Citations:    Fields:    Translation:HumansCells
    2. Campbell K, Dullea A, Ramsoomair C, Schuppe K, Ghomeshi A, Khodamoradi K, Arora H, Jorgez C, Ramasamy R. Transcriptional Differences in Identical Twins With Different Reproductive Capacities: A Case Report. Cureus. 2023 Jun; 15(6):e40847. PMID: 37492809; PMCID: PMC10363651.
      Citations:    
    3. Seth A, Bournat JC, Medina-Martinez O, Rivera A, Moore J, Flores H, Rosenfeld JA, Hu L, Jorgez CJ. Loss of WNT4 in the gubernaculum causes unilateral cryptorchidism and fertility defects. Development. 2022 12 01; 149(23). PMID: 36448532; PMCID: PMC10112923.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Seth A, Rivera A, Chahdi A, Choi IS, Medina-Martinez O, Lewis S, O'Neill M, Ridgeway A, Moore J, Jorgez C, Lamb DJ. Gene dosage changes in KCTD13 result in penile and testicular anomalies via diminished androgen receptor function. FASEB J. 2022 11; 36(11):e22567. PMID: 36196997; PMCID: PMC10538574.
      Citations: 1     Fields:    Translation:HumansAnimals
    5. Parlani M, Jorgez C, Friedl P. Plasticity of cancer invasion and energy metabolism. Trends Cell Biol. 2023 05; 33(5):388-402. PMID: 36328835; PMCID: PMC10368441.
      Citations: 3     Fields:    Translation:Humans
    6. Scovell JM, Bournat JC, Szafran AT, Solis M, Moore J, Rivera A, Chen CH, Zhang J, Wilken N, Seth A, Jorgez CJ. PRSS50 is a testis protease responsible for proper sperm tail formation and function. Development. 2021 04 15; 148(8). PMID: 33913480; PMCID: PMC8077533.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Jorgez CJ, Seth A, Wilken N, Bournat JC, Chen CH, Lamb DJ. E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling. Development. 2021 01 13; 148(1). PMID: 33441379; PMCID: PMC7823160.
      Citations: 5     Fields:    Translation:AnimalsCells
    8. Chen CH, Bournat JC, Wilken N, Rosenfeld JA, Zhang J, Seth A, Jorgez CJ. Variants in ALX4 and their association with genitourinary defects. Andrology. 2020 09; 8(5):1243-1255. PMID: 32385972; PMCID: PMC10318892.
      Citations:    Fields:    Translation:HumansCells
    9. Ren YA, Monkkonen T, Lewis MT, Bernard DJ, Christian HC, Jorgez CJ, Moore JA, Landua JD, Chin HM, Chen W, Singh S, Kim IS, Zhang XH, Xia Y, Phillips KJ, MacKay H, Waterland RA, Ljungberg MC, Saha PK, Hartig SM, Richards JS, Coll TF. S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. JCI Insight. 2019 07 02; 5. PMID: 31265437; PMCID: PMC6675546.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    10. Gerber JA, Balasubramanian A, Jorgez CJ, Shukla MA, Jacob JS, Zhu H, Sheth KR, Mittal A, Tu DD, Koh CJ, Janzen N, Wang MH, Austin PF, Gonzales ET, Roth DR, Seth A. Do pediatricians routinely perform genitourinary examinations during well-child visits? A review from a large tertiary pediatric hospital. J Pediatr Urol. 2019 Aug; 15(4):374.e1-374.e5. PMID: 31229415.
      Citations: 1     Fields:    Translation:Humans
    11. White JT, Kovar E, Chambers TM, Sheth KR, Peckham-Gregory EC, O'Neill M, Langlois PH, Jorgez CJ, Lupo PJ, Seth A. Hypospadias Risk from Maternal Residential Exposure to Heavy Metal Hazardous Air Pollutants. Int J Environ Res Public Health. 2019 03 15; 16(6). PMID: 30875870; PMCID: PMC6466330.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    12. Sheth KR, Kovar E, White JT, Chambers TM, Peckham-Gregory EC, O'Neill M, Langlois PH, Seth A, Scheurer ME, Lupo PJ, Jorgez CJ. Hypospadias risk is increased with maternal residential exposure to hormonally active hazardous air pollutants. Birth Defects Res. 2019 04 15; 111(7):345-352. PMID: 30694020; PMCID: PMC6868530.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    13. Sheth KR, White JT, Perez-Orozco AF, Debolske ND, Hyde CR, Geistkemper C, Roth DR, Austin PF, Gonzales ET, Janzen NK, Tu DD, Mittal AG, Koh CJ, Ryan SL, Jorgez C, Seth A. Evaluating Natural History and Follow Up Strategies for Non-obstructive Urolithiasis in Pediatric Population. Front Pediatr. 2018; 6:353. PMID: 30505832; PMCID: PMC6250749.
      Citations: 1     
    14. Sheriff FR, Lopez A, Lupo PJ, Seth A, Jorgez C, Agopian AJ. Maternal hypertension and hypospadias in offspring: A systematic review and meta-analysis. Birth Defects Res. 2019 01 01; 111(1):9-15. PMID: 30411533.
      Citations: 4     Fields:    Translation:Humans
    15. White JT, Sheth KR, Bilgutay AN, Roth DR, Austin PF, Gonzales ET, Janzen NK, Tu DD, Mittal AG, Koh CJ, Ryan SL, Jorgez C, Seth A. Corrigendum: Vesicoamniotic Shunting Improves Outcomes in a Subset of Prune Belly Syndrome Patients at a Single Tertiary Center. Front Pediatr. 2018; 6:229. PMID: 30140665; PMCID: PMC6102447.
      Citations: 1     
    16. Sheth KR, White JT, Stanasel I, Janzen N, Mittal A, Koh CJ, Austin PF, Roth DR, Tu DD, Gonzales ET, Ryan S, Jorgez C, Seth A. Comparing treatment modalities for transplant kidney vesicoureteral reflux in the pediatric population. J Pediatr Urol. 2018 12; 14(6):554.e1-554.e6. PMID: 30146426.
      Citations: 2     Fields:    Translation:Humans
    17. Sheth KR, White JT, Janzen N, Koh CJ, Austin PF, Roth DR, Tu DD, Mittal A, Wang MH, Gonzales ET, Jorgez C, Seth A. Evaluating Outcomes of Differential Surgical Management of Nonfunctioning Upper Pole Renal Moieties in Duplex Collecting Systems. Urology. 2019 01; 123:198-203. PMID: 30031832.
      Citations: 3     Fields:    Translation:Humans
    18. White JT, Sheth KR, Bilgutay AN, Roth DR, Austin PF, Gonzales ET, Janzen NK, Tu DD, Mittal AG, Koh CJ, Ryan SL, Jorgez C, Seth A. Vesicoamniotic Shunting Improves Outcomes in a Subset of Prune Belly Syndrome Patients at a Single Tertiary Center. Front Pediatr. 2018; 6:180. PMID: 30018947; PMCID: PMC6038357.
      Citations: 2     
    19. Dietrich JE, Adeyemi O, Hakim J, Santos X, Bercaw-Pratt JL, Bournat JC, Chen CH, Jorgez CJ. Paratubal Cyst Size Correlates With Obesity and Dysregulation of the Wnt Signaling Pathway. J Pediatr Adolesc Gynecol. 2017 Oct; 30(5):571-577. PMID: 28456695.
      Citations: 3     Fields:    Translation:HumansCells
    20. Jorgez CJ, Wilken N, Addai JB, Newberg J, Vangapandu HV, Pastuszak AW, Mukherjee S, Rosenfeld JA, Lipshultz LI, Lamb DJ. Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia. Fertil Steril. 2015 Jan; 103(1):44-52.e1. PMID: 25439843; PMCID: PMC4282601.
      Citations: 6     Fields:    Translation:HumansAnimals
    21. Jorgez CJ, Rosenfeld JA, Wilken NR, Vangapandu HV, Sahin A, Pham D, Carvalho CM, Bandholz A, Miller A, Weaver DD, Burton B, Babu D, Bamforth JS, Wilks T, Flynn DP, Roeder E, Patel A, Cheung SW, Lupski JR, Lamb DJ. Genitourinary defects associated with genomic deletions in 2p15 encompassing OTX1. PLoS One. 2014; 9(9):e107028. PMID: 25203062; PMCID: PMC4159299.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    22. Jorgez CJ, Weedin JW, Sahin A, Tannour-Louet M, Han S, Bournat JC, Mielnik A, Cheung SW, Nangia A, Schlegel PN, Lipshultz LI, Lamb DJ. Y-chromosome microdeletions are not associated with SHOX haploinsufficiency. Hum Reprod. 2014 May; 29(5):1113-4. PMID: 24634249; PMCID: PMC6296315.
      Citations: 1     Fields:    Translation:HumansCells
    23. Jorgez CJ, Weedin JW, Sahin A, Tannour-Louet M, Han S, Bournat JC, Mielnik A, Cheung SW, Nangia AK, Schlegel PN, Lipshultz LI, Lamb DJ. Aberrations in pseudoautosomal regions (PARs) found in infertile men with Y-chromosome microdeletions. J Clin Endocrinol Metab. 2011 Apr; 96(4):E674-9. PMID: 21252244; PMCID: PMC3070254.
      Citations: 25     Fields:    Translation:HumansCells
    24. Hwang K, Yatsenko AN, Jorgez CJ, Mukherjee S, Nalam RL, Matzuk MM, Lamb DJ. Mendelian genetics of male infertility. Ann N Y Acad Sci. 2010 Dec; 1214:E1-E17. PMID: 21382200; PMCID: PMC3654696.
      Citations: 13     Fields:    Translation:HumansAnimals
    25. Jorgez CJ, Bischoff FZ. Improving enrichment of circulating fetal DNA for genetic testing: size fractionation followed by whole gene amplification. Fetal Diagn Ther. 2009; 25(3):314-9. PMID: 19776594; PMCID: PMC2814146.
      Citations: 10     Fields:    Translation:Humans
    26. Orozco AF, Jorgez CJ, Ramos-Perez WD, Popek EJ, Yu X, Kozinetz CA, Bischoff FZ, Lewis DE. Placental release of distinct DNA-associated micro-particles into maternal circulation: reflective of gestation time and preeclampsia. Placenta. 2009 Oct; 30(10):891-7. PMID: 19692120; PMCID: PMC2758063.
      Citations: 29     Fields:    Translation:HumansCells
    27. Shen JJ, Huang L, Li L, Jorgez C, Matzuk MM, Brown CW. Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose. Mol Endocrinol. 2009 Jan; 23(1):113-23. PMID: 19008465; PMCID: PMC2646597.
      Citations: 30     Fields:    Translation:AnimalsCells
    28. Jorgez CJ, Bischoff FZ. Stability of placental RNA using dried maternal blood spots. Reprod Biomed Online. 2008 Nov; 17(5):716-21. PMID: 18983758.
      Citations: 1     Fields:    Translation:HumansCells
    29. Orozco AF, Jorgez CJ, Horne C, Marquez-Do DA, Chapman MR, Rodgers JR, Bischoff FZ, Lewis DE. Membrane protected apoptotic trophoblast microparticles contain nucleic acids: relevance to preeclampsia. Am J Pathol. 2008 Dec; 173(6):1595-608. PMID: 18974299; PMCID: PMC2626372.
      Citations: 25     Fields:    Translation:HumansCells
    30. Li Q, Pangas SA, Jorgez CJ, Graff JM, Weinstein M, Matzuk MM. Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. Mol Cell Biol. 2008 Dec; 28(23):7001-11. PMID: 18809571; PMCID: PMC2593383.
      Citations: 69     Fields:    Translation:AnimalsCells
    31. Pangas SA, Jorgez CJ, Tran M, Agno J, Li X, Brown CW, Kumar TR, Matzuk MM. Intraovarian activins are required for female fertility. Mol Endocrinol. 2007 Oct; 21(10):2458-71. PMID: 17609433.
      Citations: 55     Fields:    Translation:AnimalsCells
    32. Jorgez CJ, Dang DD, Wapner R, Farina A, Simpson JL, Bischoff FZ. Elevated levels of total (maternal and fetal) beta-globin DNA in maternal blood from first trimester pregnancies with trisomy 21. Hum Reprod. 2007 Aug; 22(8):2267-72. PMID: 17584747.
      Citations: 4     Fields:    Translation:Humans
    33. Jorgez CJ, Simpson JL, Bischoff FZ. Recovery and amplification of placental RNA from dried maternal blood spots: utility for non-invasive prenatal diagnosis. Reprod Biomed Online. 2006 Oct; 13(4):558-61. PMID: 17007679.
      Citations: 2     Fields:    Translation:Humans
    34. Jorgez CJ, Dang DD, Simpson JL, Lewis DE, Bischoff FZ. Quantity versus quality: optimal methods for cell-free DNA isolation from plasma of pregnant women. Genet Med. 2006 Oct; 8(10):615-9. PMID: 17079877.
      Citations: 26     Fields:    Translation:Humans
    35. Jorgez CJ, De Mayo FJ, Matzuk MM. Inhibin alpha-iCre mice: Cre deleter lines for the gonads, pituitary, and adrenal. Genesis. 2006 Apr; 44(4):183-8. PMID: 16604527.
      Citations: 5     Fields:    Translation:AnimalsCells
    36. Jorgez CJ, Lin YN, Matzuk MM. Genetic manipulations to study reproduction. Mol Cell Endocrinol. 2005 Apr 29; 234(1-2):127-35. PMID: 15836961.
      Citations: 2     Fields:    Translation:AnimalsCells
    37. Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I. Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov; 7(5):719-30. PMID: 15525533.
      Citations: 78     Fields:    Translation:AnimalsCells
    38. Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I. Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep; 231(1):98-108. PMID: 15305290.
      Citations: 21     Fields:    Translation:AnimalsCells
    39. Yao HH, Matzuk MM, Jorgez CJ, Menke DB, Page DC, Swain A, Capel B. Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn. 2004 Jun; 230(2):210-5. PMID: 15162500; PMCID: PMC4046253.
      Citations: 118     Fields:    Translation:AnimalsCells
    40. Tutuncu L, Stein P, Ord TS, Jorgez CJ, Williams CJ. Calreticulin on the mouse egg surface mediates transmembrane signaling linked to cell cycle resumption. Dev Biol. 2004 Jun 01; 270(1):246-60. PMID: 15136153.
      Citations: 15     Fields:    Translation:AnimalsCells
    41. Pangas SA, Jorgez CJ, Matzuk MM. Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin. J Biol Chem. 2004 Jul 30; 279(31):32281-6. PMID: 15133038.
      Citations: 39     Fields:    Translation:AnimalsCells
    42. Travis AJ, Tutuncu L, Jorgez CJ, Ord TS, Jones BH, Kopf GS, Williams CJ. Requirements for glucose beyond sperm capacitation during in vitro fertilization in the mouse. Biol Reprod. 2004 Jul; 71(1):139-45. PMID: 14985248.
      Citations: 16     Fields:    Translation:AnimalsCells
    43. Jorgez CJ, Klysik M, Jamin SP, Behringer RR, Matzuk MM. Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol. 2004 Apr; 18(4):953-67. PMID: 14701941.
      Citations: 90     Fields:    Translation:AnimalsCells
    44. Travis AJ, Jorgez CJ, Merdiushev T, Jones BH, Dess DM, Diaz-Cueto L, Storey BT, Kopf GS, Moss SB. Functional relationships between capacitation-dependent cell signaling and compartmentalized metabolic pathways in murine spermatozoa. J Biol Chem. 2001 Mar 09; 276(10):7630-6. PMID: 11115497.
      Citations: 59     Fields:    Translation:AnimalsCells
    45. Visconti PE, Galantino-Homer H, Ning X, Moore GD, Valenzuela JP, Jorgez CJ, Alvarez JG, Kopf GS. Cholesterol efflux-mediated signal transduction in mammalian sperm. beta-cyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation. J Biol Chem. 1999 Jan 29; 274(5):3235-42. PMID: 9915865.
      Citations: 65     Fields:    Translation:AnimalsCells
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