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Institute for Clinical and Translational Research

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Masataka Suzuki

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Hematology & Oncology
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Cell & Gene Therapy
    DivisionCenter for Cell & Gene Therapy


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    K99HL098692     (SUZUKI, MASATAKA)Aug 9, 2010 - Nov 30, 2012
    NIH/NHLBI
    Blocking the immune response to Helper-dependent adenovirus vector for Hemophilia
    Role: Principal Investigator
    R00HL098692     (SUZUKI, MASATAKA)Jan 10, 2013 - Nov 30, 2015
    NIH/NHLBI
    Blocking the immune response to HDAd for Hemophilia A gene therapy
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. McKenna MK, Rosewell-Shaw A, Suzuki M. Modeling the Efficacy of Oncolytic Adenoviruses In Vitro and In Vivo: Current and Future Perspectives. Cancers (Basel). 2020 Mar 07; 12(3). PMID: 32155969.
      View in: PubMed
    2. Porter CE, Rosewell Shaw A, Jung Y, Yip T, Castro PD, Sandulache VC, Sikora A, Gottschalk S, Ittman MM, Brenner MK, Suzuki M. Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors. Mol Ther. 2020 Feb 24. PMID: 32145203.
      View in: PubMed
    3. Suzuki M, Gonda Y, Yamada M, Vandebroek AA, Mita M, Hamase K, Yasui M, Sasabe J. Serum D-serine accumulation after proximal renal tubular damage involves neutral amino acid transporter Asc-1. Sci Rep. 2019 Nov 13; 9(1):16705. PMID: 31723194.
      View in: PubMed
    4. Shaw AR, Suzuki M. Immunology of Adenoviral Vectors in Cancer Therapy. Mol Ther Methods Clin Dev. 2019 Dec 13; 15:418-429. PMID: 31890734.
      View in: PubMed
    5. Matsushima D, Kasahara R, Matsuno K, Aoki F, Suzuki MG. Involvement of Ecdysone Signaling in the Expression of the doublesex Gene during Embryonic Development in the Silkworm, Bombyx mori. Sex Dev. 2019; 13(3):151-163. PMID: 31487710.
      View in: PubMed
    6. Rosewell Shaw A, Suzuki M. Oncolytic Viruses Partner With T-Cell Therapy for Solid Tumor Treatment. Front Immunol. 2018; 9:2103. PMID: 30298067.
      View in: PubMed
    7. Funaya S, Ooga M, Suzuki MG, Aoki F. Linker histone H1FOO regulates the chromatin structure in mouse zygotes. FEBS Lett. 2018 07; 592(14):2414-2424. PMID: 29963710.
      View in: PubMed
    8. Abe KI, Funaya S, Tsukioka D, Kawamura M, Suzuki Y, Suzuki MG, Schultz RM, Aoki F. Minor zygotic gene activation is essential for mouse preimplantation development. Proc Natl Acad Sci U S A. 2018 07 17; 115(29):E6780-E6788. PMID: 29967139.
      View in: PubMed
    9. Vial-Pradel S, Keta S, Nomoto M, Luo L, Takahashi H, Suzuki M, Yokoyama Y, Sasabe M, Kojima S, Tada Y, Machida Y, Machida C. Arabidopsis Zinc-Finger-Like Protein ASYMMETRIC LEAVES2 (AS2) and Two Nucleolar Proteins Maintain Gene Body DNA Methylation in the Leaf Polarity Gene ETTIN (ARF3). Plant Cell Physiol. 2018 Jul 01; 59(7):1385-1397. PMID: 29415182.
      View in: PubMed
    10. Tanaka A, Aoki F, Suzuki MG. Conserved Domains in the Transformer Protein Act Complementary to Regulate Sex-Specific Splicing of Its Own Pre-mRNA. Sex Dev. 2018; 12(4):180-190. PMID: 29804107.
      View in: PubMed
    11. Sasabe J, Suzuki M. Distinctive Roles of D-Amino Acids in the Homochiral World: Chirality of Amino Acids Modulates Mammalian Physiology and Pathology. Keio J Med. 2019 Mar 25; 68(1):1-16. PMID: 29794368.
      View in: PubMed
    12. Sasabe J, Suzuki M. Emerging Role of D-Amino Acid Metabolism in the Innate Defense. Front Microbiol. 2018; 9:933. PMID: 29867842.
      View in: PubMed
    13. Ooga M, Funaya S, Hashioka Y, Fujii W, Naito K, Suzuki MG, Aoki F. Chd9 mediates highly loosened chromatin structure in growing mouse oocytes. Biochem Biophys Res Commun. 2018 06 07; 500(3):583-588. PMID: 29665362.
      View in: PubMed
    14. Rosewell Shaw A, Porter CE, Watanabe N, Tanoue K, Sikora A, Gottschalk S, Brenner MK, Suzuki M. Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer. Mol Ther. 2017 11 01; 25(11):2440-2451. PMID: 28974431.
      View in: PubMed
    15. Mine S, Sumitani M, Aoki F, Hatakeyama M, Suzuki MG. Identification and functional characterization of the sex-determining gene doublesex in the sawfly, Athalia rosae (Hymenoptera: Tenthredinidae). Appl Entomol Zool. 2017; 52(3):497-509. PMID: 28798494.
      View in: PubMed
    16. Suzuki M, Imanishi N, Mita M, Hamase K, Aiso S, Sasabe J. Heterogeneity of D-Serine Distribution in the Human Central Nervous System. ASN Neuro. 2017 May-Jun; 9(3):1759091417713905. PMID: 28604057.
      View in: PubMed
    17. Suzuki M. Partners in Crime: Combining Oncolytic Viroimmunotherapy with Other Therapies. Mol Ther. 2017 04 05; 25(4):836-838. PMID: 28330695.
      View in: PubMed
    18. Tanoue K, Rosewell Shaw A, Watanabe N, Porter C, Rana B, Gottschalk S, Brenner M, Suzuki M. Armed Oncolytic Adenovirus-Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors. Cancer Res. 2017 04 15; 77(8):2040-2051. PMID: 28235763.
      View in: PubMed
    19. Wagamitsu S, Takase D, Aoki F, Suzuki MG. Identification of the Doublesex protein binding sites that activate expression of lozenge in the female genital disc in Drosophila melanogaster. Mech Dev. 2017 02; 143:26-31. PMID: 28087460.
      View in: PubMed
    20. Otsuki A, Patel A, Kasai K, Suzuki M, Kurozumi K, Antonio Chiocca E, Saeki Y. Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses. Mol Ther. 2008 Sep; 16(9):1546-1555. PMID: 28189010.
      View in: PubMed
    21. Sakai H, Sumitani M, Chikami Y, Yahata K, Uchino K, Kiuchi T, Katsuma S, Aoki F, Sezutsu H, Suzuki MG. Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori. PLoS Genet. 2016 08; 12(8):e1006203. PMID: 27579676.
      View in: PubMed
    22. Rosewell Shaw A, Suzuki M. Recent advances in oncolytic adenovirus therapies for cancer. Curr Opin Virol. 2016 12; 21:9-15. PMID: 27379906.
      View in: PubMed
    23. Sakai H, Kirino Y, Katsuma S, Aoki F, Suzuki MG. Morphological and histomorphological structures of testes and ovaries in early developmental stages of the silkworm, Bombyx mori. J Insect Biotechnol Sericology. 2016; 85(1):15-20. PMID: 28943775.
      View in: PubMed
    24. Ooga M, Fulka H, Hashimoto S, Suzuki MG, Aoki F. Analysis of chromatin structure in mouse preimplantation embryos by fluorescent recovery after photobleaching. Epigenetics. 2016; 11(1):85-94. PMID: 26901819.
      View in: PubMed
    25. Rajagopal A, Homan EP, Joeng KS, Suzuki M, Bertin T, Cela R, Munivez E, Dawson B, Jiang MM, Gannon F, Crawford S, Lee BH. Restoration of the serum level of SERPINF1 does not correct the bone phenotype in Serpinf1 null mice. Mol Genet Metab. 2016 Mar; 117(3):378-82. PMID: 26693895.
      View in: PubMed
    26. Yamamoto R, Abe K, Suzuki Y, Suzuki MG, Aoki F. Characterization of gene expression in mouse embryos at the 1-cell stage. J Reprod Dev. 2016; 62(1):87-92. PMID: 26599803.
      View in: PubMed
    27. Hoyos V, Del Bufalo F, Yagyu S, Ando M, Dotti G, Suzuki M, Bouchier-Hayes L, Alemany R, Brenner MK. Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers. Mol Ther. 2015 Sep; 23(9):1497-506. PMID: 26084970.
      View in: PubMed
    28. Abe K, Yamamoto R, Franke V, Cao M, Suzuki Y, Suzuki MG, Vlahovicek K, Svoboda P, Schultz RM, Aoki F. The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing. EMBO J. 2015 Jun 03; 34(11):1523-37. PMID: 25896510.
      View in: PubMed
    29. Suzuki MG, Tochigi M, Sakaguchi H, Aoki F, Miyamoto N. Identification of a transformer homolog in the acorn worm, Saccoglossus kowalevskii, and analysis of its activity in insect cells. Dev Genes Evol. 2015 Jun; 225(3):161-9. PMID: 25868907.
      View in: PubMed
    30. Suzuki M, Sasabe J, Miyoshi Y, Kuwasako K, Muto Y, Hamase K, Matsuoka M, Imanishi N, Aiso S. Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes. Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17):E2217-24. PMID: 25870284.
      View in: PubMed
    31. Sakai H, Sakaguchi H, Aoki F, Suzuki MG. Functional analysis of sex-determination genes by gene silencing with LNA-DNA gapmers in the silkworm, Bombyx mori. Mech Dev. 2015 Aug; 137:45-52. PMID: 25828912.
      View in: PubMed
    32. Ooga M, Suzuki MG, Aoki F. Involvement of histone H2B monoubiquitination in the regulation of mouse preimplantation development. J Reprod Dev. 2015; 61(3):179-84. PMID: 25740253.
      View in: PubMed
    33. Rogers GL, Suzuki M, Zolotukhin I, Markusic DM, Morel LM, Lee B, Ertl HC, Herzog RW. Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene Transfer. J Innate Immun. 2015; 7(3):302-14. PMID: 25612611.
      View in: PubMed
    34. Ito T, Takada H, Isobe K, Suzuki M, Kitaura Y, Hemmi H, Matsuda T, Sasabe J, Yoshimura T. PEGylated D-serine dehydratase as a D-serine reducing agent. J Pharm Biomed Anal. 2015 Dec 10; 116:34-9. PMID: 25617179.
      View in: PubMed
    35. Farzad L, Cerullo V, Yagyu S, Bertin T, Hemminki A, Rooney C, Lee B, Suzuki M. Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy. Mol Ther Oncolytics. 2014; 1:14008. PMID: 27119096.
      View in: PubMed
    36. Abe T, Suzuki M, Sasabe J, Takahashi S, Unekawa M, Mashima K, Iizumi T, Hamase K, Konno R, Aiso S, Suzuki N. Cellular origin and regulation of D- and L-serine in in vitro and in vivo models of cerebral ischemia. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1928-35. PMID: 25294127.
      View in: PubMed
    37. Sasabe J, Suzuki M, Imanishi N, Aiso S. Activity of D-amino acid oxidase is widespread in the human central nervous system. Front Synaptic Neurosci. 2014; 6:14. PMID: 24959138.
      View in: PubMed
    38. Kiuchi T, Koga H, Kawamoto M, Shoji K, Sakai H, Arai Y, Ishihara G, Kawaoka S, Sugano S, Shimada T, Suzuki Y, Suzuki MG, Katsuma S. A single female-specific piRNA is the primary determiner of sex in the silkworm. Nature. 2014 May 29; 509(7502):633-6. PMID: 24828047.
      View in: PubMed
    39. Suzuki MG, Ito H, Aoki F. Effects of RNAi-mediated knockdown of histone methyltransferases on the sex-specific mRNA expression of Imp in the silkworm Bombyx mori. Int J Mol Sci. 2014 Apr 22; 15(4):6772-96. PMID: 24758924.
      View in: PubMed
    40. Yukawa M, Akiyama T, Franke V, Mise N, Isagawa T, Suzuki Y, Suzuki MG, Vlahovicek K, Abe K, Aburatani H, Aoki F. Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells. PLoS One. 2014; 9(3):e92689. PMID: 24658136.
      View in: PubMed
    41. Farzad LM, Suzuki M. Feasibility of Applying Helper-Dependent Adenoviral Vectors for Cancer Immunotherapy. Biomedicines. 2014 Mar 10; 2(1):110-131. PMID: 28548063.
      View in: PubMed
    42. Sasabe J, Suzuki M, Miyoshi Y, Tojo Y, Okamura C, Ito S, Konno R, Mita M, Hamase K, Aiso S. Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: early detection of renal dysfunction using the ratio of serine enantiomers. PLoS One. 2014; 9(1):e86504. PMID: 24489731.
      View in: PubMed
    43. Sakai H, Aoki F, Suzuki MG. Identification of the key stages for sex determination in the silkworm, Bombyx mori. Dev Genes Evol. 2014 Mar; 224(2):119-23. PMID: 24346480.
      View in: PubMed
    44. Suzuki MG, Kobayashi S, Aoki F. Male-specific splicing of the silkworm Imp gene is maintained by an autoregulatory mechanism. Mech Dev. 2014 Feb; 131:47-56. PMID: 24231282.
      View in: PubMed
    45. Suzuki M, Bertin TK, Rogers GL, Cela RG, Zolotukhin I, Palmer DJ, Ng P, Herzog RW, Lee B. Differential type I interferon-dependent transgene silencing of helper-dependent adenoviral vs. adeno-associated viral vectors in vivo. Mol Ther. 2013 Apr; 21(4):796-805. PMID: 23319058.
      View in: PubMed
    46. Suzuki M, Rooney CM. Adenovirus immunity: X marks the spot. Mol Ther. 2012 Dec; 20(12):2197-8. PMID: 23201614.
      View in: PubMed
    47. Breman A, Patel A. Preparation of chorionic villus samples for metaphase chromosome analysis and chromosomal microarray analysis. Curr Protoc Hum Genet. 2012 Oct; Chapter 8:Unit8.3. PMID: 23074072.
      View in: PubMed
    48. Guse K, Suzuki M, Sule G, Bertin TK, Tyynismaa H, Ahola-Erkkilä S, Palmer D, Suomalainen A, Ng P, Cerullo V, Hemminki A, Lee B. Capsid-modified adenoviral vectors for improved muscle-directed gene therapy. Hum Gene Ther. 2012 Oct; 23(10):1065-70. PMID: 22888960.
      View in: PubMed
    49. Suzuki M, Sasabe J, Furuya S, Mita M, Hamase K, Aiso S. Type 1 diabetes mellitus in mice increases hippocampal D-serine in the acute phase after streptozotocin injection. Brain Res. 2012 Jul 23; 1466:167-76. PMID: 22652304.
      View in: PubMed
    50. Sule G, Suzuki M, Guse K, Cela R, Rodgers JR, Lee B. Cytokine-conditioned dendritic cells induce humoral tolerance to protein therapy in mice. Hum Gene Ther. 2012 Jul; 23(7):769-80. PMID: 22468961.
      View in: PubMed
    51. Breman A, Pursley AN, Hixson P, Bi W, Ward P, Bacino CA, Shaw C, Lupski JR, Beaudet A, Patel A, Cheung SW, Van den Veyver I. Prenatal chromosomal microarray analysis in a diagnostic laboratory; experience with >1000 cases and review of the literature. Prenat Diagn. 2012 Apr; 32(4):351-61. PMID: 22467166.
      View in: PubMed
    52. Bi W, Breman A, Shaw CA, Stankiewicz P, Gambin T, Lu X, Cheung SW, Jackson LG, Lupski JR, Van den Veyver IB, Beaudet AL. Detection of =1Mb microdeletions and microduplications in a single cell using custom oligonucleotide arrays. Prenat Diagn. 2012 Jan; 32(1):10-20. PMID: 22470934.
      View in: PubMed
    53. Suzuki M, Cela R, Bertin TK, Sule G, Cerullo V, Rodgers JR, Lee B. NOD2 signaling contributes to the innate immune response against helper-dependent adenovirus vectors independently of MyD88 in vivo. Hum Gene Ther. 2011 Sep; 22(9):1071-82. PMID: 21561248.
      View in: PubMed
    54. Oshima J, Lee JA, Breman AM, Fernandes PH, Babovic-Vuksanovic D, Ward PA, Wolfe LA, Eng CM, Del Gaudio D. LCR-initiated rearrangements at the IDS locus, completed with Alu-mediated recombination or non-homologous end joining. J Hum Genet. 2011 Jul; 56(7):516-23. PMID: 21593745.
      View in: PubMed
    55. Breman AM, Probst FJ, Blazo MA, Schaaf CP, Roney EK, Craigen WJ, Bacino CA, Cheung SW. Identification of complex chromosome 18 rearrangements by FISH and array CGH in two patients with apparent isochromosome 18q. Am J Med Genet A. 2011 Jun; 155A(6):1465-8. PMID: 21567909.
      View in: PubMed
    56. Martino AT, Suzuki M, Markusic DM, Zolotukhin I, Ryals RC, Moghimi B, Ertl HC, Muruve DA, Lee B, Herzog RW. The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver. Blood. 2011 Jun 16; 117(24):6459-68. PMID: 21474674.
      View in: PubMed
    57. Hu C, Cela RG, Suzuki M, Lee B, Lipshutz GS. Neonatal helper-dependent adenoviral vector gene therapy mediates correction of hemophilia A and tolerance to human factor VIII. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):2082-7. PMID: 21245323.
      View in: PubMed
    58. Ou Z, Stankiewicz P, Xia Z, Breman AM, Dawson B, Wiszniewska J, Szafranski P, Cooper ML, Rao M, Shao L, South ST, Coleman K, Fernhoff PM, Deray MJ, Rosengren S, Roeder ER, Enciso VB, Chinault AC, Patel A, Kang SH, Shaw CA, Lupski JR, Cheung SW. Observation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes. Genome Res. 2011 Jan; 21(1):33-46. PMID: 21205869.
      View in: PubMed
    59. Breman AM, Ramocki MB, Kang SH, Williams M, Freedenberg D, Patel A, Bader PI, Cheung SW. MECP2 duplications in six patients with complex sex chromosome rearrangements. Eur J Hum Genet. 2011 Apr; 19(4):409-15. PMID: 21119712.
      View in: PubMed
    60. Suzuki M, Cerullo V, Bertin TK, Cela R, Clarke C, Guenther M, Brunetti-Pierri N, Lee B. MyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus. Hum Gene Ther. 2010 Mar; 21(3):325-36. PMID: 19824822.
      View in: PubMed
    61. El-Hattab AW, Skorupski JC, Hsieh MH, Breman AM, Patel A, Cheung SW, Craigen WJ. OEIS complex associated with chromosome 1p36 deletion: a case report and review. Am J Med Genet A. 2010 Feb; 152A(2):504-11. PMID: 20101692.
      View in: PubMed
    62. Suzuki M, Cela R, Clarke C, Bertin TK, Mouriño S, Lee B. Large-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories. Hum Gene Ther. 2010 Jan; 21(1):120-6. PMID: 19719388.
      View in: PubMed
    63. Breman AM, Bi WM, Cheung SW. Prenatal diagnosis by array-based comparative genomic hybridization in the clinical laboratory setting. Beijing Da Xue Xue Bao Yi Xue Ban. 2009 Aug 18; 41(4):500-4. PMID: 19727248.
      View in: PubMed
    64. Wat MJ, Shchelochkov OA, Holder AM, Breman AM, Dagli A, Bacino C, Scaglia F, Zori RT, Cheung SW, Scott DA, Kang SH. Chromosome 8p23.1 deletions as a cause of complex congenital heart defects and diaphragmatic hernia. Am J Med Genet A. 2009 Aug; 149A(8):1661-77. PMID: 19606479.
      View in: PubMed
    65. Grimes BR, Steiner CM, Merfeld-Clauss S, Traktuev DO, Smith D, Reese A, Breman AM, Thurston VC, Vance GH, Johnstone BH, Slee RB, March KL. Interphase FISH demonstrates that human adipose stromal cells maintain a high level of genomic stability in long-term culture. Stem Cells Dev. 2009 Jun; 18(5):717-24. PMID: 18754715.
      View in: PubMed
    66. Oshima J, Magner DB, Lee JA, Breman AM, Schmitt ES, White LD, Crowe CA, Merrill M, Jayakar P, Rajadhyaksha A, Eng CM, del Gaudio D. Regional genomic instability predisposes to complex dystrophin gene rearrangements. Hum Genet. 2009 Sep; 126(3):411-23. PMID: 19449031.
      View in: PubMed
    67. Suzuki M, Kasai K, Ohtsuki A, Godlewski J, Nowicki MO, Chiocca EA, Saeki Y. ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression. Mol Ther. 2009 Apr; 17(4):707-15. PMID: 19223864.
      View in: PubMed
    68. Bi W, Breman AM, Venable SF, Eng PA, Sahoo T, Lu XY, Patel A, Beaudet AL, Cheung SW, White LD. Rapid prenatal diagnosis using uncultured amniocytes and oligonucleotide array CGH. Prenat Diagn. 2008 Oct; 28(10):943-9. PMID: 18792925.
      View in: PubMed
    69. Suzuki M, Chiocca EA, Saeki Y. Stable transgene expression from HSV amplicon vectors in the brain: potential involvement of immunoregulatory signals. Mol Ther. 2008 Oct; 16(10):1727-36. PMID: 18728642.
      View in: PubMed
    70. Otsuki A, Patel A, Kasai K, Suzuki M, Kurozumi K, Chiocca EA, Saeki Y. Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses. Mol Ther. 2008 Sep; 16(9):1546-55. PMID: 18648350.
      View in: PubMed
    71. Liang Z, Breman AM, Grimes BR, Rosen ED. Identifying and genotyping transgene integration loci. Transgenic Res. 2008 Oct; 17(5):979-83. PMID: 18612840.
      View in: PubMed
    72. Breman AM, Steiner CM, Slee RB, Grimes BR. Input DNA ratio determines copy number of the 33 kb Factor IX gene on de novo human artificial chromosomes. Mol Ther. 2008 Feb; 16(2):315-23. PMID: 18059371.
      View in: PubMed
    73. Suzuki M, Chiocca EA, Saeki Y. Early STAT1 activation after systemic delivery of HSV amplicon vectors suppresses transcription of the vector-encoded transgene. Mol Ther. 2007 Nov; 15(11):2017-26. PMID: 17653098.
      View in: PubMed
    74. Suzuki M, Kasai K, Saeki Y. Plasmid DNA sequences present in conventional herpes simplex virus amplicon vectors cause rapid transgene silencing by forming inactive chromatin. J Virol. 2006 Apr; 80(7):3293-300. PMID: 16537596.
      View in: PubMed
    75. Suzuki M, Takayanagi A, Shimizu N. Targeted gene delivery using humanized single-chain antibody with negatively charged oligopeptide tail. Cancer Sci. 2004 May; 95(5):424-9. PMID: 15132770.
      View in: PubMed
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