"Bile Acids and Salts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.
| Descriptor ID |
D001647
|
| MeSH Number(s) |
D04.210.500.105
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bile Acids and Salts".
Below are MeSH descriptors whose meaning is more specific than "Bile Acids and Salts".
This graph shows the total number of publications written about "Bile Acids and Salts" by people in this website by year, and whether "Bile Acids and Salts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 |
| 1998 | 3 | 0 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 2 | 5 |
| 2001 | 3 | 0 | 3 |
| 2002 | 2 | 0 | 2 |
| 2003 | 5 | 1 | 6 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 2 | 4 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 3 | 1 | 4 |
| 2010 | 5 | 2 | 7 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 7 | 1 | 8 |
| 2014 | 1 | 3 | 4 |
| 2015 | 6 | 1 | 7 |
| 2016 | 3 | 3 | 6 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 7 | 1 | 8 |
| 2020 | 5 | 3 | 8 |
| 2021 | 7 | 3 | 10 |
| 2022 | 6 | 5 | 11 |
| 2023 | 1 | 9 | 10 |
| 2024 | 3 | 4 | 7 |
| 2025 | 8 | 4 | 12 |
| 2026 | 4 | 1 | 5 |
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Below are the most recent publications written about "Bile Acids and Salts" by people in Profiles.
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mTORC1-TFEB/TFE3 signaling is associated with bile acid diversification during hepatic metabolic adaptation. Sci Adv. 2026 Sep 25; 12(39):eaee1905.
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Bile Acid Synthesis and Metabolism Disorders. Clin Liver Dis. 2026 Nov; 30(4):1009-1021.
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Tobacco smoking disrupts bile acid and tryptophan metabolism in multiple sclerosis. Mult Scler. 2026 Aug; 32(9):972-984.
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Constitutive AMPK activation prevents hepatocellular carcinoma development through inhibition of HNF4a activity. Sci Adv. 2026 Apr 10; 12(15):eaea8017.
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Myosin 5b deficiency alters liver proliferation, zonation, and bile acid composition. Hepatol Commun. 2026 Mar 01; 10(3).
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Beyond bile acids synthesis: metabolomics profiling highlights extensive metabolic dysregulation and treatment response in CTX. Orphanet J Rare Dis. 2026 Jan 30; 21(1).
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Bile acids as mitochondrial toxins: emerging insights in fontan and heart failure with preserved ejection fraction. Can J Physiol Pharmacol. 2026 Jan 01; 104:1-9.
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A Randomized Phase 1 Study Investigating Gut Microbiome Changes With Moxifloxacin vs Oral Vancomycin: Implications for Clostridioides difficile Risk. J Infect Dis. 2025 Dec 20; 232(6):1446-1456.
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Faecal pharmacokinetics, microbiome, and bile acid changes in healthy subjects given intravenous followed by oral omadacycline; a Phase 1 clinical trial. J Antimicrob Chemother. 2025 10 03; 80(10):2719-2726.
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Selective agonism of liver and gut FXR prevents cholestasis and intestinal atrophy in parenterally fed neonatal pigs. J Lipid Res. 2025 11; 66(11):100919.