"Protein C Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)
| Descriptor ID |
D020151
|
| MeSH Number(s) |
C15.378.100.100.690 C15.378.147.880 C15.378.925.795 C16.320.099.690
|
| Concept/Terms |
Protein C Deficiency- Protein C Deficiency
- Hereditary Thrombophilia Due To Protein C Deficiency
- Deficiency, Protein C
- Deficiencies, Protein C
- Protein C Deficiencies
|
Below are MeSH descriptors whose meaning is more general than "Protein C Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Protein C Deficiency".
This graph shows the total number of publications written about "Protein C Deficiency" by people in this website by year, and whether "Protein C Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Protein C Deficiency" by people in Profiles.
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Dabigatran in the treatment and secondary prophylaxis of venous thromboembolism in children with thrombophilia. Blood Adv. 2022 11 22; 6(22):5908-5923.
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Diagnosis and management of severe congenital protein C deficiency (SCPCD): Communication from the SSC of the ISTH. J Thromb Haemost. 2022 07; 20(7):1735-1743.
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Protein C Deficiency. Arch Pathol Lab Med. 2019 10; 143(10):1281-1285.
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Acquired Versus Congenital Neonatal Purpura Fulminans: A Case Report and Literature Review. J Pediatr Hematol Oncol. 2018 11; 40(8):625-627.
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Efficacy and safety of protein C concentrate to treat purpura fulminans and thromboembolic events in severe congenital protein C deficiency. Thromb Haemost. 2016 07 04; 116(1):58-68.
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Protein C Thr315Ala variant results in gain of function but manifests as type II deficiency in diagnostic assays. Blood. 2015 Apr 09; 125(15):2428-34.
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Right-to-left interatrial shunt with hypoxemia caused by a right atrial thrombus. Tex Heart Inst J. 2007; 34(2):225-9.
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Management of neonatal purpura fulminans with severe protein C deficiency. Indian Pediatr. 2006 Jun; 43(6):542-5.
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Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis. Pediatrics. 2004 Jan; 113(1 Pt 1):7-17.
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Lateral dural sinus thrombosis in childhood. Laryngoscope. 1999 Apr; 109(4):645-51.