"Heavy Chain Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.
- gamma-Chain Disease
- gamma Chain Disease
- gamma-Chain Diseases
- Franklin Disease
- Franklin's Disease
- Franklins Disease
Below are MeSH descriptors whose meaning is more general than "Heavy Chain Disease".
Below are MeSH descriptors whose meaning is more specific than "Heavy Chain Disease".
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