"Computational Biology" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.
| Descriptor ID |
D019295
|
| MeSH Number(s) |
H01.158.273.180 L01.313.124
|
| Concept/Terms |
Computational Molecular Biology- Computational Molecular Biology
- Biologies, Computational Molecular
- Biology, Computational Molecular
- Computational Molecular Biologies
- Molecular Biologies, Computational
- Molecular Biology, Computational
Bio-Informatics- Bio-Informatics
- Bio Informatics
- Bio-Informatic
- Bioinformatics
- Bioinformatic
|
Below are MeSH descriptors whose meaning is more general than "Computational Biology".
Below are MeSH descriptors whose meaning is more specific than "Computational Biology".
This graph shows the total number of publications written about "Computational Biology" by people in this website by year, and whether "Computational Biology" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 2 | 2 | 4 |
| 2001 | 3 | 1 | 4 |
| 2002 | 2 | 1 | 3 |
| 2003 | 4 | 5 | 9 |
| 2004 | 8 | 13 | 21 |
| 2005 | 7 | 11 | 18 |
| 2006 | 14 | 14 | 28 |
| 2007 | 3 | 11 | 14 |
| 2008 | 6 | 12 | 18 |
| 2009 | 7 | 13 | 20 |
| 2010 | 7 | 14 | 21 |
| 2011 | 3 | 18 | 21 |
| 2012 | 9 | 13 | 22 |
| 2013 | 13 | 20 | 33 |
| 2014 | 11 | 14 | 25 |
| 2015 | 3 | 18 | 21 |
| 2016 | 12 | 16 | 28 |
| 2017 | 16 | 24 | 40 |
| 2018 | 11 | 21 | 32 |
| 2019 | 25 | 17 | 42 |
| 2020 | 16 | 17 | 33 |
| 2021 | 12 | 18 | 30 |
| 2022 | 3 | 8 | 11 |
| 2023 | 2 | 6 | 8 |
| 2024 | 2 | 15 | 17 |
| 2025 | 1 | 4 | 5 |
To return to the timeline,
click here.
Below are the most recent publications written about "Computational Biology" by people in Profiles.
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Advancements in protein structure prediction: A comparative overview of AlphaFold and its derivatives. Comput Biol Med. 2025 Apr; 188:109842.
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Evaluating predictors of kinase activity of STK11 variants identified in primary human non-small cell lung cancers. Hum Genet. 2025 Mar; 144(2-3):127-142.
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Resolving tissue complexity by multimodal spatial omics modeling with MISO. Nat Methods. 2025 Mar; 22(3):530-538.
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DesiRNA: structure-based design of RNA sequences with a replica exchange Monte Carlo approach. Nucleic Acids Res. 2025 Jan 11; 53(2).
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CAGI6 ID panel challenge: assessment of phenotype and variant predictions in 415 children with neurodevelopmental disorders (NDDs). Hum Genet. 2025 Mar; 144(2-3):227-242.
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Causal models and prediction in cell line perturbation experiments. BMC Bioinformatics. 2025 Jan 07; 26(1):4.
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Meta-EA: a gene-specific combination of available computational tools for predicting missense variant effects. Nat Commun. 2025 01 02; 16(1):159.
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Leveraging human microbiomes for disease prediction and treatment. Trends Pharmacol Sci. 2025 Jan; 46(1):32-44.
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RNA-Puzzles Round V: blind predictions of 23 RNA structures. Nat Methods. 2025 Feb; 22(2):399-411.
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Experiences in providing a community educational resource for the All of Us Researcher Workbench. J Am Med Inform Assoc. 2024 Dec 01; 31(12):2952-2957.