"Galectin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A galectin found abundantly in smooth muscle (MUSCLE, SMOOTH) and SKELETAL MUSCLE and many other tissues. It occurs as a homodimer with two 14-kDa subunits.
| Descriptor ID |
D037483
|
| MeSH Number(s) |
D12.776.503.307.100
|
| Concept/Terms |
Galectin 1- Galectin 1
- Galaptin
- Galectin-1
- L1-Lac Lectin
- L1 Lac Lectin
- Lectin, L1-Lac
- LGALS1
- Galactoside-Binding Lectin 1
- Galactoside Binding Lectin 1
- Lectin 1, Galactoside-Binding
- L-14 Lectin
- Lectin, L-14
|
Below are MeSH descriptors whose meaning is more general than "Galectin 1".
Below are MeSH descriptors whose meaning is more specific than "Galectin 1".
This graph shows the total number of publications written about "Galectin 1" by people in this website by year, and whether "Galectin 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Galectin 1" by people in Profiles.
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LGALS1 acts as a pro-survival molecule in AML. Biochim Biophys Acta Mol Cell Res. 2020 10; 1867(10):118785.
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Molecular characterization, tissue distribution and functional analysis of galectin 1-like 2 in grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol. 2019 Nov; 94:455-463.
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Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3769-E3778.
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In Vivo Hemin Conditioning Targets the Vascular and Immunologic Compartments and Restrains Prostate Tumor Development. Clin Cancer Res. 2017 Sep 01; 23(17):5135-5148.
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Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets. Oncotarget. 2016 Apr 05; 7(14):18183-203.
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Galectin-1 and immune suppression during radiotherapy. Clin Cancer Res. 2014 Dec 15; 20(24):6230-2.
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Galectin-1 mediates radiation-related lymphopenia and attenuates NSCLC radiation response. Clin Cancer Res. 2014 Nov 01; 20(21):5558-69.
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Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation. Cancer Res. 2014 Jul 01; 74(13):3512-24.
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Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma. Cancer Biol Ther. 2012 Aug; 13(10):899-907.
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Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis. Cancer Res. 2011 Jul 01; 71(13):4423-31.