"Antidepressive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
| Descriptor ID |
D000928
|
| MeSH Number(s) |
D27.505.954.427.700.122
|
| Concept/Terms |
Antidepressive Agents- Antidepressive Agents
- Agents, Antidepressive
- Antidepressant Drugs
- Drugs, Antidepressant
- Antidepressants
|
Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents".
This graph shows the total number of publications written about "Antidepressive Agents" by people in this website by year, and whether "Antidepressive Agents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 2 | 4 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 3 | 1 | 4 |
| 2005 | 2 | 8 | 10 |
| 2006 | 5 | 3 | 8 |
| 2007 | 2 | 2 | 4 |
| 2008 | 6 | 4 | 10 |
| 2009 | 5 | 3 | 8 |
| 2010 | 4 | 4 | 8 |
| 2011 | 8 | 4 | 12 |
| 2012 | 6 | 3 | 9 |
| 2013 | 6 | 3 | 9 |
| 2014 | 5 | 4 | 9 |
| 2015 | 8 | 3 | 11 |
| 2016 | 6 | 1 | 7 |
| 2017 | 9 | 5 | 14 |
| 2018 | 9 | 7 | 16 |
| 2019 | 8 | 5 | 13 |
| 2020 | 6 | 12 | 18 |
| 2021 | 2 | 1 | 3 |
| 2022 | 2 | 16 | 18 |
| 2023 | 4 | 11 | 15 |
| 2024 | 10 | 3 | 13 |
| 2025 | 11 | 3 | 14 |
| 2026 | 6 | 1 | 7 |
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Below are the most recent publications written about "Antidepressive Agents" by people in Profiles.
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Interdisciplinary, Delphi-driven consensus guidelines on the use of intravenous ketamine infusions for depressive disorders from the American Society of Ketamine Physicians, Psychotherapists, and Practitioners (ASKP3). J Affect Disord. 2026 Oct 15; 411:121970.
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Patient treatment preference as a predictor of clinical outcomes in subjects with treatment-resistant depression: a comparative effectiveness research trial for antidepressant incomplete and nonresponders with treatment-resistant depression (ASCERTAIN-TRD). Int Clin Psychopharmacol. 2026 May 01; 41(3):184-191.
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Combination of Antidepressants and Chemotherapeutic Agents to Overcome P-Glycoprotein-Mediated Resistance in Cancer Patients: A Systematic Review. Med Sci (Basel). 2026 Mar 07; 14(1).
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Understanding initial medication adherence amongst major depressive disorder patients: A scoping review. J Am Pharm Assoc (2003). 2026 May-Jun; 66(3):103061.
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Depression severity and efficacy outcomes: post hoc analyses from a phase 3 trial of esmethadone for the adjunctive treatment of major depressive disorder with inadequate response to standard antidepressants. Int Clin Psychopharmacol. 2026 Jul 01; 41(4):213-224.
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Use of a Medication Management Algorithm in Depressed Youth Living with HIV: Secondary Analysis of a Multisite Randomized Controlled Trial. J Child Adolesc Psychopharmacol. 2026 Jan; 36(1):21-28.
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Screening, diagnosing, and managing perinatal depression: Review of SIX national guidelines. Eur J Obstet Gynecol Reprod Biol. 2026 Mar; 319:114977.
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Real-World Use, Effectiveness and Tolerability of Antidepressant Treatment in Oncology Patients. Psychooncology. 2025 Dec; 34(12):e70340.
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A Practical Primer on How to Detect and Treat Depression in CKD. Am J Kidney Dis. 2026 Feb; 87(2):239-245.
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Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group. Mol Psychiatry. 2025 Dec; 30(12):5625-5636.