Glycine Dehydrogenase (Decarboxylating)
"Glycine Dehydrogenase (Decarboxylating)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.
| Descriptor ID |
D050841
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| MeSH Number(s) |
D05.500.562.452.200 D08.811.600.391.200 D08.811.682.664.500.498.500
|
| Concept/Terms |
Glycine Dehydrogenase (Decarboxylating)- Glycine Dehydrogenase (Decarboxylating)
- P-protein, Glycine Decarboxylase
- Decarboxylase P-protein, Glycine
- Glycine Decarboxylase P-protein
- P protein, Glycine Decarboxylase
- Glycine Decarboxylase Complex P-Protein
- Glycine Decarboxylase Complex P Protein
- Glycine Cleavage System P-Protein
- Glycine Cleavage System P Protein
- Glycine Decarboxylase
- Decarboxylase, Glycine
|
Below are MeSH descriptors whose meaning is more general than "Glycine Dehydrogenase (Decarboxylating)".
Below are MeSH descriptors whose meaning is more specific than "Glycine Dehydrogenase (Decarboxylating)".
This graph shows the total number of publications written about "Glycine Dehydrogenase (Decarboxylating)" by people in this website by year, and whether "Glycine Dehydrogenase (Decarboxylating)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glycine Dehydrogenase (Decarboxylating)" by people in Profiles.
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Genetic variants in ALDH1L1 and GLDC influence the serine-to-glycine ratio in Hispanic children. Am J Clin Nutr. 2022 08 04; 116(2):500-510.
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Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene. Biol Psychiatry. 2019 10 01; 86(7):523-535.
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Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice. Nat Commun. 2015 Mar 04; 6:6388.
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Regulation of hepatic glycine catabolism by glucagon. J Biol Chem. 1989 Feb 25; 264(6):3347-51.
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Increased activity of renal glycine-cleavage-enzyme complex in metabolic acidosis. Biochem J. 1985 Oct 15; 231(2):477-80.