"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 0 | 3 |
| 2008 | 8 | 5 | 13 |
| 2009 | 16 | 5 | 21 |
| 2010 | 23 | 6 | 29 |
| 2011 | 29 | 12 | 41 |
| 2012 | 21 | 5 | 26 |
| 2013 | 46 | 8 | 54 |
| 2014 | 33 | 7 | 40 |
| 2015 | 45 | 8 | 53 |
| 2016 | 37 | 8 | 45 |
| 2017 | 32 | 10 | 42 |
| 2018 | 29 | 10 | 39 |
| 2019 | 25 | 10 | 35 |
| 2020 | 27 | 10 | 37 |
| 2021 | 23 | 11 | 34 |
| 2022 | 13 | 0 | 13 |
| 2023 | 23 | 0 | 23 |
| 2024 | 14 | 5 | 19 |
| 2025 | 11 | 6 | 17 |
| 2026 | 4 | 0 | 4 |
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click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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MiR-200c restoration inhibits FOXP3 and metastatic spread in breast cancer: evidence from in vitro and in vivo models. BMC Cancer. 2026 Feb 14; 26(1).
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Exosomes Derived From Bone Marrow Macrophages of HFD-Fed Mice Regulating AKT/GSK Pathway in Hepatocytes via miR-222-5p. FASEB J. 2026 Jan 15; 40(1):e71380.
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An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis independent of tissue-specific Microprocessor condensates. Genes Dev. 2026 Jan 05; 40(1-2):26-42.
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miR-302 regulates pancreatic progenitor pool and pancreatic size. Biol Open. 2026 Jan 01; 15(1).
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Tumor miRNA Signatures Associate with Outcomes of Patients with Stage II/III Melanoma. Clin Cancer Res. 2025 Dec 15; 31(24):5225-5236.
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Sperm and offspring production in a nonobstructive azoospermia mouse model via testicular mRNA delivery using lipid nanoparticles. Proc Natl Acad Sci U S A. 2025 Oct 21; 122(42):e2516573122.
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Type I interferon limits central nervous system autoimmunity by modulating the microRNA-21-FOXO1 axis in pathogenic T helper 17 cells. Sci Transl Med. 2025 Sep 10; 17(815):eadp5802.
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Identifying bio-behavioural signatures of persistent opioid use risk in trauma injury patients: a protocol for a prospective cohort study. BMJ Open. 2025 Sep 05; 15(9):e103053.
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Mechano-Signal Transduction Pathways of the Diaphragmatic Muscle and Role of Cytoskeleton. Genes (Basel). 2025 Aug 18; 16(8).
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In2O3 Nanoribbon-Based Field-Effect Transistor Biosensors for Ultrasensitive Detection of Exosomal Circulating microRNA with Peptide Nucleic Acid Probes. ACS Nano. 2025 Aug 19; 19(32):29726-29736.