"Masoprocol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
| Descriptor ID |
D009637
|
| MeSH Number(s) |
D02.455.426.559.389.140.450.582 D02.455.426.559.389.657.166.550
|
| Concept/Terms |
Masoprocol- Masoprocol
- (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
- Nordihydroguaiaretic Acid
- Nordihydroguaiaretic Acid, (R*,S*)-Isomer
- Dihydronorguaiaretic Acid
- meso-Nordihydroguaiaretic Acid
- Acid, meso-Nordihydroguaiaretic
- meso Nordihydroguaiaretic Acid
|
Below are MeSH descriptors whose meaning is more general than "Masoprocol".
Below are MeSH descriptors whose meaning is more specific than "Masoprocol".
This graph shows the total number of publications written about "Masoprocol" by people in this website by year, and whether "Masoprocol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Masoprocol" by people in Profiles.
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Acarbose, 17-?-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell. 2014 Apr; 13(2):273-82.
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Nordihydroguaiaretic acid (NDGA) inhibits ritonavir-induced endothelial dysfunction in porcine pulmonary arteries. Med Sci Monit. 2011 Nov; 17(11):BR312-318.
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Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: an update. Med Sci Monit. 2010 May; 16(5):RA93-100.
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Oxidative stress in NSC-741909-induced apoptosis of cancer cells. J Transl Med. 2010 Apr 16; 8:37.
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Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. Carcinogenesis. 2002 Dec; 23(12):2095-102.