"Masoprocol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
| Descriptor ID |
D009637
|
| MeSH Number(s) |
D02.455.426.559.389.140.450.582 D02.455.426.559.389.657.166.550
|
| Concept/Terms |
Masoprocol- Masoprocol
- (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
- Nordihydroguaiaretic Acid
- Nordihydroguaiaretic Acid, (R*,S*)-Isomer
- Dihydronorguaiaretic Acid
- meso-Nordihydroguaiaretic Acid
- Acid, meso-Nordihydroguaiaretic
- meso Nordihydroguaiaretic Acid
|
Below are MeSH descriptors whose meaning is more general than "Masoprocol".
Below are MeSH descriptors whose meaning is more specific than "Masoprocol".
This graph shows the total number of publications written about "Masoprocol" by people in this website by year, and whether "Masoprocol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Masoprocol" by people in Profiles.
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Nordihydroguaiaretic acid (NDGA) inhibits ritonavir-induced endothelial dysfunction in porcine pulmonary arteries. Med Sci Monit. 2011 Nov; 17(11):BR312-318.
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Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: an update. Med Sci Monit. 2010 May; 16(5):RA93-100.
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Oxidative stress in NSC-741909-induced apoptosis of cancer cells. J Transl Med. 2010 Apr 16; 8:37.
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Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin. Leuk Lymphoma. 2007 Apr; 48(4):774-85.
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CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target. Am J Surg Pathol. 2005 Mar; 29(3):390-9.
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Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. Carcinogenesis. 2002 Dec; 23(12):2095-102.
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Identification of an annexin-like protein and its possible role in the Aplysia eye circadian system. J Neurochem. 1993 Oct; 61(4):1236-45.
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Blockade of epidermal growth factor-induced uterine contractions by indomethacin or nordihydroguaritic acid. J Pharmacol Exp Ther. 1989 Sep; 250(3):882-6.
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Modulation of human marrow haematopoiesis by leucotrienes in vitro. Br J Haematol. 1988 Jul; 69(3):321-7.