"Cytosine Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE.
| Descriptor ID |
D043525
|
| MeSH Number(s) |
D08.811.277.151.486.625
|
| Concept/Terms |
Cytosine Deaminase- Cytosine Deaminase
- Deaminase, Cytosine
- Cytosine Aminohydrolase
- Aminohydrolase, Cytosine
|
Below are MeSH descriptors whose meaning is more general than "Cytosine Deaminase".
Below are MeSH descriptors whose meaning is more specific than "Cytosine Deaminase".
This graph shows the total number of publications written about "Cytosine Deaminase" by people in this website by year, and whether "Cytosine Deaminase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 7 | 7 |
| 2003 | 0 | 1 | 1 |
| 2004 | 3 | 0 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 3 | 0 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytosine Deaminase" by people in Profiles.
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Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes. Hum Genomics. 2019 08 20; 13(1):37.
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APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa. Sci Transl Med. 2018 08 22; 10(455).
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Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. Neurosurgery. 2016 Sep; 79(3):481-91.
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HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation. Retrovirology. 2015 Jul 10; 12:60.
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Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase. Mol Cancer Ther. 2011 Aug; 10(8):1327-36.
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Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay. Clin Cancer Res. 2010 Apr 15; 16(8):2308-19.
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Transcriptional control of activation-induced cytidine deaminase and error-prone DNA polymerases is functionally mature in the B cells of infants at birth. Hum Immunol. 2006 Jan-Feb; 67(1-2):43-6.
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Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells. Cancer Res. 2006 Jan 01; 66(1):378-84.
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Fusion of the HSV-1 tegument protein vp22 to cytosine deaminase confers enhanced bystander effect and increased therapeutic benefit. Gene Ther. 2006 Jan; 13(2):127-37.
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DNA polymerases and somatic hypermutation of immunoglobulin genes. EMBO Rep. 2005 Dec; 6(12):1143-8.