"G(M3) Ganglioside" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
| Descriptor ID |
D005679
|
| MeSH Number(s) |
D09.400.410.420.025.475.510 D10.390.470.025.475.510 D10.570.877.360.025.475.510
|
| Concept/Terms |
G(M3) Ganglioside- G(M3) Ganglioside
- Sialyl Lactosylceramide
- Lactosylceramide, Sialyl
- Ganglioside GM3
- GM3, Ganglioside
- Hematoside
- Sialyllactosylceramide
- II3NeuAcLacCer
|
Below are MeSH descriptors whose meaning is more general than "G(M3) Ganglioside".
Below are MeSH descriptors whose meaning is more specific than "G(M3) Ganglioside".
This graph shows the total number of publications written about "G(M3) Ganglioside" by people in this website by year, and whether "G(M3) Ganglioside" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "G(M3) Ganglioside" by people in Profiles.
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Fernandez LE, Gabri MR, Guthmann MD, Gomez RE, Gold S, Fainboim L, Gomez DE, Alonso DF. NGcGM3 ganglioside: a privileged target for cancer vaccines. Clin Dev Immunol. 2010; 2010:814397.
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Gabri MR, Otero LL, Gomez DE, Alonso DF. Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines. J Exp Clin Cancer Res. 2009 Dec 01; 28:146.
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Bitton RJ, Guthmann MD, Gabri MR, Carnero AJ, Alonso DF, Fainboim L, Gomez DE. Cancer vaccines: an update with special focus on ganglioside antigens. Oncol Rep. 2002 Mar-Apr; 9(2):267-76.
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Gillard BK, Thurmon LT, Marcus DM. Association of glycosphingolipids with intermediate filaments of mesenchymal, epithelial, glial, and muscle cells. Cell Motil Cytoskeleton. 1992; 21(4):255-71.
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Gillard BK, Heath JP, Thurmon LT, Marcus DM. Association of glycosphingolipids with intermediate filaments of human umbilical vein endothelial cells. Exp Cell Res. 1991 Feb; 192(2):433-44.
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Kundu SK, Marcus DM, Veh RW. Preparation and properties of antibodies to GD3 and GM1 gangliosides. J Neurochem. 1980 Jan; 34(1):184-8.