 Multiple Sclerosis
"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
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| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
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| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
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Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 2 | 0 | 2 | | 1990 | 2 | 1 | 3 | | 1991 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 3 | 1 | 4 | | 1994 | 1 | 1 | 2 | | 1995 | 2 | 1 | 3 | | 1997 | 2 | 1 | 3 | | 2000 | 0 | 1 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 6 | 1 | 7 | | 2003 | 5 | 1 | 6 | | 2004 | 8 | 1 | 9 | | 2005 | 8 | 2 | 10 | | 2006 | 1 | 0 | 1 | | 2007 | 5 | 2 | 7 | | 2008 | 2 | 0 | 2 | | 2009 | 2 | 2 | 4 | | 2010 | 4 | 0 | 4 | | 2011 | 3 | 1 | 4 | | 2012 | 1 | 1 | 2 | | 2013 | 2 | 1 | 3 | | 2014 | 5 | 0 | 5 | | 2015 | 2 | 1 | 3 | | 2016 | 3 | 0 | 3 | | 2017 | 5 | 3 | 8 | | 2018 | 4 | 1 | 5 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, Krupp L, Gorman M, Benson L, Chitnis T, Mar S, Belman A, Casper TC, Rose J, Moodley M, Rensel M, Rodriguez M, Greenberg B, Kahn L, Rubin J, Schaefer C, Waubant E, Langer-Gould A, Barcellos LF. Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry. PLoS Genet. 2019 01; 15(1):e1007808.
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Khavari R, Elias SN, Pande R, Wu KM, Boone TB, Karmonik C. Higher Neural Correlates in Patients with Multiple Sclerosis and Neurogenic Overactive Bladder Following Treatment with Intradetrusor Injection of OnabotulinumtoxinA. J Urol. 2019 01; 201(1):135-140.
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Chong I, Wang KY, Lincoln CM. Cryptococcal meningitis in a multiple sclerosis patient treated with Fingolimod: a case report and review of imaging findings. Clin Imaging. 2019 Mar - Apr; 54:53-56.
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Krysko KM, Graves J, Rensel M, Weinstock-Guttman B, Aaen G, Benson L, Chitnis T, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Rodriguez M, Rose J, Waltz M, Charles Casper T, Waubant E. Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US. Neurology. 2018 11 06; 91(19):e1778-e1787.
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Mika KM, Li X, DeMayo FJ, Lynch VJ. An Ancient Fecundability-Associated Polymorphism Creates a GATA2 Binding Site in a Distal Enhancer of HLA-F. Am J Hum Genet. 2018 10 04; 103(4):509-521.
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Uittenbogaard M, Brantner CA, Fang Z, Wong LJ, Gropman A, Chiaramello A. The m.11778 A?>?G variant associated with the coexistence of Leber's hereditary optic neuropathy and multiple sclerosis-like illness dysregulates the metabolic interplay between mitochondrial oxidative phosphorylation and glycolysis. Mitochondrion. 2019 05; 46:187-194.
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Wang KY, Uribe TA, Lincoln CM. Comparing lesion detection of infratentorial multiple sclerosis lesions between T2-weighted spin-echo, 2D-FLAIR, and 3D-FLAIR sequences. Clin Imaging. 2018 Sep - Oct; 51:229-234.
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Suleiman L, Waubant E, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Gorman M, Goyal M, Greenberg B, Harris Y, Hart J, Kahn I, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Nourbakhsh B, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Casper TC, Waltz M, Graves JS. Early infectious exposures are not associated with increased risk of pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2018 May; 22:103-107.
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Lincoln CM, Fata P, Sotardi S, Pohlen M, Uribe T, Bello JA. Imaging spectrum of immunomodulating, chemotherapeutic and radiation therapy-related intracranial effects. Br J Radiol. 2018 Feb; 91(1082):20170553.
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Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waubant E. Examining the contributions of environmental quality to pediatric multiple sclerosis. Mult Scler Relat Disord. 2017 Nov; 18:164-169.
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