"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
|
| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
|
| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
|
Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 3 | 2 | 5 |
| 1999 | 4 | 0 | 4 |
| 2000 | 4 | 2 | 6 |
| 2001 | 7 | 1 | 8 |
| 2002 | 8 | 1 | 9 |
| 2003 | 10 | 1 | 11 |
| 2004 | 9 | 0 | 9 |
| 2005 | 7 | 1 | 8 |
| 2006 | 1 | 0 | 1 |
| 2007 | 5 | 1 | 6 |
| 2008 | 6 | 0 | 6 |
| 2009 | 8 | 1 | 9 |
| 2010 | 8 | 0 | 8 |
| 2011 | 9 | 1 | 10 |
| 2012 | 5 | 1 | 6 |
| 2013 | 9 | 1 | 10 |
| 2014 | 10 | 1 | 11 |
| 2015 | 6 | 1 | 7 |
| 2016 | 6 | 0 | 6 |
| 2017 | 13 | 2 | 15 |
| 2018 | 6 | 3 | 9 |
| 2019 | 14 | 1 | 15 |
| 2020 | 18 | 2 | 20 |
| 2021 | 15 | 1 | 16 |
| 2022 | 18 | 0 | 18 |
| 2023 | 19 | 0 | 19 |
| 2024 | 18 | 3 | 21 |
| 2025 | 17 | 0 | 17 |
| 2026 | 8 | 1 | 9 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Reframing the Gut-Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases. Ann Neurol. 2026 Nov; 100(5):915-930.
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Genome-wide association analyses highlight the neuronal contribution to multiple sclerosis susceptibility. Nat Genet. 2026 Sep; 58(9):2177-2191.
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Perceived pain and its association with physical functioning in older adults with and without multiple sclerosis. Mult Scler Relat Disord. 2026 Nov; 115:107912.
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Longitudinal stability of dietary intake patterns in pediatric-onset multiple sclerosis: A multicenter prospective cohort study. Mult Scler Relat Disord. 2026 Nov; 115:107677.
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Tolebrutinib liver safety: A detailed overview. Mult Scler Relat Disord. 2026 Sep; 113:107404.
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DIscontinuation of disease-modifying therapies in older adults with multiple sclerosis. Mult Scler Relat Disord. 2026 Sep; 113:107378.
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Tobacco smoking disrupts bile acid and tryptophan metabolism in multiple sclerosis. Mult Scler. 2026 Aug; 32(9):972-984.
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Adaptation of the Transition Readiness Assessment Questionnaire for Pediatric-Onset Multiple Sclerosis: Protocol for a User-Centered Design Approach. JMIR Res Protoc. 2026 06 24; 15:e91763.
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Cell-type- and state-resolved transcriptomics uncovers distinct T cell and monocyte dysregulation in multiple sclerosis. Cell Rep. 2026 Jun 23; 45(6):117417.
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Disease-modifying treatment preferences and decision-making in a multiple sclerosis randomized and observational clinical trial (DELIVER-MS). Mult Scler. 2026 Jun; 32(7):722-736.