"Tunicamycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.
| Descriptor ID |
D014415
|
| MeSH Number(s) |
D03.383.742.680.725 D13.570.685.725
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tunicamycin".
Below are MeSH descriptors whose meaning is more specific than "Tunicamycin".
This graph shows the total number of publications written about "Tunicamycin" by people in this website by year, and whether "Tunicamycin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tunicamycin" by people in Profiles.
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Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):9586-9591.
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BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3192-3197.
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PLIN2 is a Key Regulator of the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic ? Cells. Sci Rep. 2017 01 19; 7:40855.
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Moderate endoplasmic reticulum stress activates a PERK and p38-dependent apoptosis. Cell Stress Chaperones. 2017 01; 22(1):43-54.
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Neuronatin is a stress-responsive protein of rod photoreceptors. Neuroscience. 2016 07 22; 328:1-8.
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Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin. J Biol Chem. 2011 Aug 19; 286(33):29127-29138.
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Requirement of voltage-dependent anion channel 2 for pro-apoptotic activity of Bax. Oncogene. 2009 Oct 08; 28(40):3563-72.
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Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress. Neoplasia. 2008 Feb; 10(2):160-7.
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Proteasome inhibition induces differential heat shock protein response but not unfolded protein response in HepG2 cells. J Cell Biochem. 2006 Nov 01; 99(4):1085-95.
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Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res. 2005 Dec 15; 65(24):11658-66.