Succinate-Semialdehyde Dehydrogenase
"Succinate-Semialdehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).
| Descriptor ID |
D050644
|
| MeSH Number(s) |
D08.811.682.657.163.843
|
| Concept/Terms |
Succinate-Semialdehyde Dehydrogenase- Succinate-Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate-Semialdehyde
- Succinate Semialdehyde Dehydrogenase
- Dehydrogenase, Succinate Semialdehyde
- Semialdehyde Dehydrogenase, Succinate
- Succinic Semialdehyde Dehydrogenase
- Dehydrogenase, Succinic Semialdehyde
- Semialdehyde Dehydrogenase, Succinic
- NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
|
Below are MeSH descriptors whose meaning is more general than "Succinate-Semialdehyde Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate-Semialdehyde Dehydrogenase".
This graph shows the total number of publications written about "Succinate-Semialdehyde Dehydrogenase" by people in this website by year, and whether "Succinate-Semialdehyde Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Succinate-Semialdehyde Dehydrogenase" by people in Profiles.
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Consensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency. Mol Genet Metab. 2024 May; 142(1):108363.
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Assessing Prevalence and Carrier Frequency of Succinic Semialdehyde Dehydrogenase Deficiency. J Child Neurol. 2021 11; 36(13-14):1218-1222.