Phosphogluconate Dehydrogenase
"Phosphogluconate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the oxidoreductase class that catalyzes the reaction 6-phospho-D-gluconate and NADP+ to yield D-ribulose 5-phosphate, carbon dioxide, and NADPH. The reaction is a step in the pentose phosphate pathway of glucose metabolism. (From Dorland, 27th ed) EC 1.1.1.43.
| Descriptor ID |
D010734
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| MeSH Number(s) |
D08.811.682.047.150.600
|
| Concept/Terms |
Phosphogluconate Dehydrogenase- Phosphogluconate Dehydrogenase
- Dehydrogenase, Phosphogluconate
- 6-Phosphogluconate Dehydrogenase
- 6 Phosphogluconate Dehydrogenase
- Dehydrogenase, 6-Phosphogluconate
|
Below are MeSH descriptors whose meaning is more general than "Phosphogluconate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Phosphogluconate Dehydrogenase".
This graph shows the total number of publications written about "Phosphogluconate Dehydrogenase" by people in this website by year, and whether "Phosphogluconate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Phosphogluconate Dehydrogenase" by people in Profiles.
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Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens. Commun Biol. 2020 06 25; 3(1):328.
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Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer. Nat Cell Biol. 2020 04; 22(4):476-486.
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Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation. Cell Rep. 2019 01 08; 26(2):469-482.e5.
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Defects of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in Neurospora and their pleiotropic effects. Curr Top Cell Regul. 1976; 10:205-36.