"1,2-Dimethylhydrazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
| Descriptor ID |
D019813
|
| MeSH Number(s) |
D02.442.600.400.200
|
| Concept/Terms |
1,2-Dimethylhydrazine- 1,2-Dimethylhydrazine
- 1,2 Dimethylhydrazine
- 1,2-Dimethyl-hydrazine
- 1,2 Dimethyl hydrazine
- N,N'-Dimethylhydrazine
- N,N' Dimethylhydrazine
|
Below are MeSH descriptors whose meaning is more general than "1,2-Dimethylhydrazine".
Below are MeSH descriptors whose meaning is more specific than "1,2-Dimethylhydrazine".
This graph shows the total number of publications written about "1,2-Dimethylhydrazine" by people in this website by year, and whether "1,2-Dimethylhydrazine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "1,2-Dimethylhydrazine" by people in Profiles.
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Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Mol Cell Biochem. 2019 Jan; 451(1-2):117-129.
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Protective effect of p-methoxycinnamic acid, an active phenolic acid against 1,2-dimethylhydrazine-induced colon carcinogenesis: modulating biotransforming bacterial enzymes and xenobiotic metabolizing enzymes. Mol Cell Biochem. 2014 Sep; 394(1-2):187-98.
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The effect of rosmarinic acid on 1,2-dimethylhydrazine induced colon carcinogenesis. Exp Toxicol Pathol. 2013 May; 65(4):409-18.
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Relative resistance of SGK1 knockout mice against chemical carcinogenesis. IUBMB Life. 2009 Jul; 61(7):768-76.
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High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine. J Cancer Res Clin Oncol. 2003 Jun; 129(6):335-40.
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Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas. Mol Cell Biol. 1990 Nov; 10(11):5728-35.