Enkephalin, D-Penicillamine (2,5)-
"Enkephalin, D-Penicillamine (2,5)-" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disulfide opioid pentapeptide that selectively binds to the DELTA OPIOID RECEPTOR. It possesses antinociceptive activity.
| Descriptor ID |
D020881
|
| MeSH Number(s) |
D12.644.400.575.281.600 D12.776.631.650.575.281.600
|
| Concept/Terms |
Enkephalin, D-Penicillamine (2,5)-- Enkephalin, D-Penicillamine (2,5)-
- DPDPE(SH)2
- Enkephalin, Penicillamine (2,5)-
- D-Pen2, D-Pen5-Enkephalin
- D Pen2, D Pen5 Enkephalin
- D-Pen5-Enkephalin D-Pen2
- D-Penicillamine (2,5)-Enkephalin
- DPDPE
- Enkephalin, Pen(2,5)-
|
Below are MeSH descriptors whose meaning is more general than "Enkephalin, D-Penicillamine (2,5)-".
Below are MeSH descriptors whose meaning is more specific than "Enkephalin, D-Penicillamine (2,5)-".
This graph shows the total number of publications written about "Enkephalin, D-Penicillamine (2,5)-" by people in this website by year, and whether "Enkephalin, D-Penicillamine (2,5)-" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Enkephalin, D-Penicillamine (2,5)-" by people in Profiles.
-
Delta-opioid augments cardiac contraction through ?-adrenergic and CGRP-receptor co-signaling. Peptides. 2012 Jan; 33(1):77-82.
-
Reducing ischaemia/reperfusion injury through delta-opioid-regulated intrinsic cardiac adrenergic cells: adrenopeptidergic co-signalling. Cardiovasc Res. 2009 Dec 01; 84(3):452-60.
-
Removing TRPV1-expressing primary afferent neurons potentiates the spinal analgesic effect of delta-opioid agonists on mechano-nociception. Neuropharmacology. 2008 Aug; 55(2):215-22.
-
Distinct inhibition of voltage-activated Ca2+ channels by delta-opioid agonists in dorsal root ganglion neurons devoid of functional T-type Ca2+ currents. Neuroscience. 2008 Jun 02; 153(4):1256-67.
-
Mediating delta-opioid-initiated heart protection via the beta2-adrenergic receptor: role of the intrinsic cardiac adrenergic cell. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H376-84.
-
Spinal nitric oxide contributes to the analgesic effect of intrathecal [d-pen2,d-pen5]-enkephalin in normal and diabetic rats. Anesthesiology. 2003 Jan; 98(1):217-22.
-
Role of spinal nitric oxide in the inhibitory effect of [D-Pen2, D-Pen5]-enkephalin on ascending dorsal horn neurons in normal and diabetic rats. J Pharmacol Exp Ther. 2002 Dec; 303(3):1021-8.
-
Activation of delta-opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs. J Neurophysiol. 2002 Nov; 88(5):2675-83.
-
Opioid actions on single nucleus raphe magnus neurons from rat and guinea-pig in vitro. J Physiol. 1990 Aug; 427:519-32.