"Mice, Inbred mdx" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of mice arising from a spontaneous MUTATION (mdx) in inbred C57BL mice. This mutation is X chromosome-linked and produces viable homozygous animals that lack the muscle protein DYSTROPHIN, have high serum levels of muscle ENZYMES, and possess histological lesions similar to human MUSCULAR DYSTROPHY. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE MUSCULAR DYSTROPHY.
| Descriptor ID |
D018101
|
| MeSH Number(s) |
B01.050.050.199.520.520.420.500 B01.050.150.900.649.313.992.635.505.500.400.420.500 B01.050.150.900.649.313.992.635.505.500.550.265
|
| Concept/Terms |
Mice, Inbred mdx- Mice, Inbred mdx
- Inbred mdx Mice
- Mouse, Inbred mdx
- Inbred mdx Mouse
- Mice, mdx
- mdx Mice
- Mouse, mdx
- mdx Mouse
|
Below are MeSH descriptors whose meaning is more general than "Mice, Inbred mdx".
- Organisms [B]
- Eukaryota [B01]
- Animals [B01.050]
- Animal Population Groups [B01.050.050]
- Animals, Laboratory [B01.050.050.199]
- Animals, Inbred Strains [B01.050.050.199.520]
- Mice, Inbred Strains [B01.050.050.199.520.520]
- Mice, Inbred C57BL [B01.050.050.199.520.520.420]
- Mice, Inbred mdx [B01.050.050.199.520.520.420.500]
- Chordata [B01.050.150]
- Vertebrates [B01.050.150.900]
- Mammals [B01.050.150.900.649]
- Eutheria [B01.050.150.900.649.313]
- Rodentia [B01.050.150.900.649.313.992]
- Muridae [B01.050.150.900.649.313.992.635]
- Murinae [B01.050.150.900.649.313.992.635.505]
- Mice [B01.050.150.900.649.313.992.635.505.500]
- Mice, Inbred Strains [B01.050.150.900.649.313.992.635.505.500.400]
- Mice, Inbred C57BL [B01.050.150.900.649.313.992.635.505.500.400.420]
- Mice, Inbred mdx [B01.050.150.900.649.313.992.635.505.500.400.420.500]
- Mice, Mutant Strains [B01.050.150.900.649.313.992.635.505.500.550]
- Mice, Inbred mdx [B01.050.150.900.649.313.992.635.505.500.550.265]
Below are MeSH descriptors whose meaning is more specific than "Mice, Inbred mdx".
This graph shows the total number of publications written about "Mice, Inbred mdx" by people in this website by year, and whether "Mice, Inbred mdx" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2018 | 0 | 4 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 6 | 6 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Mice, Inbred mdx" by people in Profiles.
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A microtubule-connexin-43 regulatory link suppresses arrhythmias and cardiac fibrosis in Duchenne muscular dystrophy mice. Am J Physiol Heart Circ Physiol. 2022 11 01; 323(5):H983-H995.
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Inhibition of Rev-erba ameliorates muscular dystrophy. Exp Cell Res. 2021 09 15; 406(2):112766.
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MyoSight-semi-automated image analysis of skeletal muscle cross sections. Skelet Muscle. 2020 11 16; 10(1):33.
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The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin. Nat Cell Biol. 2020 11; 22(11):1332-1345.
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Motor axonopathies in a mouse model of Duchenne muscular dystrophy. Sci Rep. 2020 06 02; 10(1):8967.
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Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle. Redox Biol. 2020 09; 36:101557.
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Exclusive vital labeling of myonuclei for studying myonuclear arrangement in mouse skeletal muscle tissue. Skelet Muscle. 2020 05 07; 10(1):15.
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Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. J Clin Invest. 2020 04 01; 130(4):1713-1727.
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In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy. Dis Model Mech. 2019 12 09; 13(2).
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Cycles of myofiber degeneration and regeneration lead to remodeling of the neuromuscular junction in two mammalian models of Duchenne muscular dystrophy. PLoS One. 2018; 13(10):e0205926.