Vascular Endothelial Growth Factor C
"Vascular Endothelial Growth Factor C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vascular endothelial growth factor that specifically binds to VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 and VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3. In addition to being an angiogenic factor it can act on LYMPHATIC VESSELS to stimulate LYMPHANGIOGENESIS. It is similar in structure to VASCULAR ENDOTHELIAL GROWTH FACTOR D in that they both contain N- and C-terminal extensions that were not found in other VEGF family members.
| Descriptor ID |
D042582
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| MeSH Number(s) |
D12.644.276.100.800.400 D12.776.467.100.800.400 D23.529.100.800.400
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor C".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor C".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor C" by people in this website by year, and whether "Vascular Endothelial Growth Factor C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor C" by people in Profiles.
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VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk. Oncogene. 2021 02; 40(5):964-979.
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Genetic variations in the transforming growth factor beta pathway as predictors of bladder cancer risk. PLoS One. 2012; 7(12):e51758.
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Increased vascular endothelial growth factor-C expression is insufficient to induce lymphatic metastasis in human soft-tissue sarcomas. Clin Cancer Res. 2009 Apr 15; 15(8):2637-46.
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Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis. Kidney Int. 2007 Apr; 71(8):771-7.