"Pancreas, Exocrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM.
| Descriptor ID |
D046790
|
| MeSH Number(s) |
A03.734.540 A10.336.645
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pancreas, Exocrine".
Below are MeSH descriptors whose meaning is more specific than "Pancreas, Exocrine".
This graph shows the total number of publications written about "Pancreas, Exocrine" by people in this website by year, and whether "Pancreas, Exocrine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreas, Exocrine" by people in Profiles.
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Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling. Development. 2023 01 15; 150(2).
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ELAPOR1 is a secretory granule maturation-promoting factor that is lost during paligenosis. Am J Physiol Gastrointest Liver Physiol. 2022 01 01; 322(1):G49-G65.
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Alterations in pancreatic islet cell function in response to small bowel resection. Am J Physiol Gastrointest Liver Physiol. 2020 07 01; 319(1):G36-G42.
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Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6622-6629.
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Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2019 01 01; 316(1):G179-G186.
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Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features. J Clin Invest. 2017 Nov 01; 127(11):4090-4103.
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The ACE2-angiotensin-(1-7)-Mas axis protects against pancreatic cell damage in cell culture. Pancreas. 2015 Mar; 44(2):266-72.
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Pancreatic enzyme replacement therapy for pancreatic exocrine insufficiency in the 21(st) century. World J Gastroenterol. 2014 Sep 07; 20(33):11467-85.
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The role of protein synthesis and digestive enzymes in acinar cell injury. Nat Rev Gastroenterol Hepatol. 2013 Jun; 10(6):362-70.
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Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice. Gastroenterology. 2011 Oct; 141(4):1451-62, 1462.e1-6.