"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
| Descriptor ID |
D000779
|
| MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
|
| Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
|
Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 1 | 2 |
| 1995 | 3 | 0 | 3 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 4 | 1 | 5 |
| 2000 | 2 | 0 | 2 |
| 2001 | 4 | 0 | 4 |
| 2002 | 3 | 1 | 4 |
| 2003 | 2 | 3 | 5 |
| 2004 | 2 | 2 | 4 |
| 2005 | 1 | 2 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 1 | 2 |
| 2008 | 5 | 2 | 7 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 4 | 1 | 5 |
| 2013 | 4 | 4 | 8 |
| 2014 | 2 | 1 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 3 | 5 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 3 | 6 |
| 2020 | 3 | 4 | 7 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.
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Davidson RS, Donaldson K, Jeffries M, Khandelwal S, Raizman M, Rodriguez Torres Y, Kim T. Persistent opioid use in cataract surgery pain management and the role of nonopioid alternatives. J Cataract Refract Surg. 2022 06 01; 48(6):730-740.
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Javed S, Chen J, Huh B. Predictors of response to medial branch block, radiofrequency ablation or facet joint injections: a retrospective study. Pain Manag. 2021 Mar; 11(2):145-149.
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Mace SE, Whiteman P, Avarello JT, Ojo A, Rose E, Valente J, Joseph M. Local and Topical Anesthetics for Pediatric Patients in the Emergency Department. Pediatr Emerg Care. 2020 Dec; 36(12):593-601.
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Patrinely JR, Darragh C, Frank N, Danford BC, Wheless L, Clayton A. Risk of adverse events due to high volumes of local anesthesia during Mohs micrographic surgery. Arch Dermatol Res. 2021 Oct; 313(8):679-684.
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Corsini EM, Mitchell KG, Zhou N, Antonoff MB, Mehran RJ, Mena GE, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC, Hofstetter WL. Liposomal Bupivacaine Intercostal Block Is Important for Reduction of Pulmonary Complications. Ann Thorac Surg. 2021 08; 112(2):423-429.
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Meyer LA, Corzo C, Iniesta MD, Munsell M, Shi Q, Pitcher B, Lasala J, Cain KE, Wang XS, Mena G, Ramirez PT. A prospective randomized trial comparing liposomal bupivacaine vs standard bupivacaine wound infiltration in open gynecologic surgery on an enhanced recovery pathway. Am J Obstet Gynecol. 2021 01; 224(1):70.e1-70.e11.
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Zhang H, Yang L, Zhu X, Zhu M, Sun Z, Cata JP, Chen W, Miao C. Association between intraoperative intravenous lidocaine infusion and survival in patients undergoing pancreatectomy for pancreatic cancer: a retrospective study. Br J Anaesth. 2020 08; 125(2):141-148.
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Cata JP, Ramirez MF, Perez-Gonzalez O. Local Anesthetics: Hunting for the Holy Grail of Onco-anesthesia. Pain Med. 2020 02 01; 21(2):219-220.
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Meftah M, Boenerjous-Abel S, Siddappa VH, Kirschenbaum IH. Efficacy of Adductor Canal Block With Liposomal Bupivacaine: A Randomized Prospective Clinical Trial. Orthopedics. 2020 Jan 01; 43(1):e47-e53.
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Patrinely JR, Johnson SP, Drolet BC. Trigger Finger Corticosteroid Injection With and Without Local Anesthetic: A Randomized, Double-Blind Controlled Trial. Hand (N Y). 2021 09; 16(5):619-623.