"Substance P" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.
| Descriptor ID |
D013373
|
| MeSH Number(s) |
D12.644.276.812.900.866 D12.644.400.800.750 D12.644.456.800.866 D12.776.467.812.900.866 D12.776.631.650.800.750 D23.469.050.375.850.890 D23.529.812.900.866
|
| Concept/Terms |
Substance P- Substance P
- Euler-Gaddum Substance P
- Euler Gaddum Substance P
- Substance P, Euler-Gaddum
- SP(1-11)
|
Below are MeSH descriptors whose meaning is more general than "Substance P".
Below are MeSH descriptors whose meaning is more specific than "Substance P".
This graph shows the total number of publications written about "Substance P" by people in this website by year, and whether "Substance P" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 3 | 4 |
| 1995 | 1 | 3 | 4 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 2 | 3 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 1 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Substance P" by people in Profiles.
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The Repurposing of Non-Peptide Neurokinin-1 Receptor Antagonists as Antitumor Drugs: An Urgent Challenge for Aprepitant. Int J Mol Sci. 2023 Nov 03; 24(21).
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Combination Therapy of Chemotherapy or Radiotherapy and the Neurokinin-1 Receptor Antagonist Aprepitant: A New Antitumor Strategy? Curr Med Chem. 2023; 30(16):1798-1812.
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A Potential Role for Substance P in West Nile Virus Neuropathogenesis. Viruses. 2022 09 04; 14(9).
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Supramammillary regulation of locomotion and hippocampal activity. Science. 2021 Dec 17; 374(6574):1492-1496.
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Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential. Mol Psychiatry. 2018 08; 23(8):1745-1755.
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Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn. Neuron. 2017 Apr 19; 94(2):294-303.e4.
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Cytokine and neuropeptide levels are associated with pain relief in patients with chronically painful total knee arthroplasty: a pilot study. BMC Musculoskelet Disord. 2017 01 14; 18(1):17.
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Pathophysiology, Evaluation, and Management of Chronic Watery Diarrhea. Gastroenterology. 2017 02; 152(3):515-532.e2.
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Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway. Oncotarget. 2016 Apr 05; 7(14):18146-58.
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Somatostatin negatively regulates parasite burden and granulomatous responses in cysticercosis. Biomed Res Int. 2014; 2014:247182.