Adrenergic alpha-Antagonists
"Adrenergic alpha-Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
| Descriptor ID |
D000317
|
| MeSH Number(s) |
D27.505.519.625.050.200.100 D27.505.696.577.050.200.100
|
| Concept/Terms |
Adrenergic alpha-Antagonists- Adrenergic alpha-Antagonists
- Adrenergic alpha Antagonists
- alpha-Antagonists, Adrenergic
- Adrenergic alpha-Receptor Blockaders
- Adrenergic alpha Receptor Blockaders
- Blockaders, Adrenergic alpha-Receptor
- alpha-Receptor Blockaders, Adrenergic
- alpha-Adrenergic Blocking Agents
- Agents, alpha-Adrenergic Blocking
- Blocking Agents, alpha-Adrenergic
- alpha Adrenergic Blocking Agents
- alpha-Adrenergic Blockers
- Blockers, alpha-Adrenergic
- alpha Adrenergic Blockers
- alpha-Blockers, Adrenergic
- alpha Blockers, Adrenergic
- alpha-Adrenergic Receptor Blockaders
- Blockaders, alpha-Adrenergic Receptor
- Receptor Blockaders, alpha-Adrenergic
- alpha Adrenergic Receptor Blockaders
- Adrenergic alpha-Blockers
- Adrenergic alpha Blockers
|
Below are MeSH descriptors whose meaning is more general than "Adrenergic alpha-Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Adrenergic alpha-Antagonists".
This graph shows the total number of publications written about "Adrenergic alpha-Antagonists" by people in this website by year, and whether "Adrenergic alpha-Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 3 | 5 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adrenergic alpha-Antagonists" by people in Profiles.
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GRK2 in sensory neurons regulates epinephrine-induced signalling and duration of mechanical hyperalgesia. Pain. 2011 Jul; 152(7):1649-1658.
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Electroacupuncture suppresses capsaicin-induced secondary hyperalgesia through an endogenous spinal opioid mechanism. Pain. 2009 Oct; 145(3):332-340.
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Stimulation of alpha(1)-adrenoceptors reduces glutamatergic synaptic input from primary afferents through GABA(A) receptors and T-type Ca(2+) channels. Neuroscience. 2009 Feb 18; 158(4):1616-24.
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The hemodynamic effects of phenoxybenzamine in neonates, infants, and children. J Clin Anesth. 2008 Mar; 20(2):94-8.
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Chiral separation of racemate CPU86017, an anti-arrhythmic agent, produces stereoisomers possessing favourable ion channel blockade and less alpha-adrenoceptor antagonism. Clin Exp Pharmacol Physiol. 2008 May; 35(5-6):643-50.
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Prospective multicenter evaluation of cataract surgery in patients taking tamsulosin (Flomax). Ophthalmology. 2007 May; 114(5):957-64.
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Regulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors. J Neurophysiol. 2005 Jan; 93(1):393-402.
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Evidence favoring the use of an alpha2-selective vasopressor agent for cardiopulmonary resuscitation. Circulation. 2003 Nov 25; 108(21):2716-21.
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Alpha blocker therapy for children with dysfunctional voiding and urinary retention. J Urol. 2003 Oct; 170(4 Pt 2):1514-5; discussion 1516-7.
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Inhibition of glutamatergic synaptic input to spinal lamina II(o) neurons by presynaptic alpha(2)-adrenergic receptors. J Neurophysiol. 2002 Apr; 87(4):1938-47.