Neural Tube Defects

"Neural Tube Defects" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)

Descriptor ID	D009436
MeSH Number(s)	C10.500.680 C16.131.666.680
Concept/Terms	Neural Tube Defects Neural Tube Defects Defect, Neural Tube Defects, Neural Tube Neural Tube Defect Developmental Neural Tube Defects Neural Tube Developmental Defects Developmental Defects, Neural Tube Craniorachischisis Craniorachischisis Craniorachischises Diastematomyelia Diastematomyelia Diastematomyelias Tethered Cord Syndrome Tethered Cord Syndrome Tethered Cord Syndromes Occult Spinal Dysraphism Sequence Tethered Spinal Cord Syndrome Occult Spinal Dysraphism Dysraphism, Occult Spinal Dysraphisms, Occult Spinal Occult Spinal Dysraphisms Spinal Dysraphism, Occult Spinal Dysraphisms, Occult Iniencephaly Iniencephaly Iniencephalies Neurenteric Cyst Neurenteric Cyst Cyst, Neurenteric Cysts, Neurenteric Neurenteric Cysts Neuroenteric Cyst Cyst, Neuroenteric Cysts, Neuroenteric Neuroenteric Cysts Spinal Cord Myelodysplasia Spinal Cord Myelodysplasia Myelodysplasia, Spinal Cord Myelodysplasias, Spinal Cord Spinal Cord Myelodysplasias Acrania Acrania Acranias Exencephaly Exencephaly Exencephalies

Below are MeSH descriptors whose meaning is more general than "Neural Tube Defects".

Diseases [C]
Nervous System Diseases [C10]
Nervous System Malformations [C10.500]
Neural Tube Defects [C10.500.680]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Congenital Abnormalities [C16.131]
Nervous System Malformations [C16.131.666]
Neural Tube Defects [C16.131.666.680]

Below are MeSH descriptors whose meaning is related to "Neural Tube Defects".

Below are MeSH descriptors whose meaning is more specific than "Neural Tube Defects".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neural Tube Defects" by people in this website by year, and whether "Neural Tube Defects" was a major or minor topic of these publications.

Bar chart showing 186 publications over 30 distinct years, with a maximum of 15 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1993	1	0	1
1995	1	1	2
1996	5	0	5
1997	3	1	4
1998	2	0	2
1999	2	0	2
2000	5	0	5
2001	6	1	7
2002	4	3	7
2003	11	0	11
2004	4	0	4
2005	2	2	4
2006	3	3	6
2007	3	1	4
2008	5	2	7
2009	4	3	7
2010	7	3	10
2011	4	1	5
2012	5	2	7
2013	6	2	8
2014	10	2	12
2015	0	1	1
2016	1	1	2
2017	6	2	8
2018	10	3	13
2019	8	3	11
2020	14	1	15
2021	13	1	14
2022	1	0	1

Below are the most recent publications written about "Neural Tube Defects" by people in Profiles.

Pi X, Wang D, Wang C, Li Z, Wang L, Yue W, Yin C, Jin L, Ren A. Placental concentrations of alkali metals and their associations with neural tube defects in offspring. Placenta. 2022 04; 121:46-52.

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Wolujewicz P, Steele JW, Kaltschmidt JA, Finnell RH, Ross ME. Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back. Genesis. 2021 11; 59(11):e23459.

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Yin S, Tian T, Wang C, Wang D, Pi X, Liu M, Jin L, Liu J, Wang L, Li Z, Ren A, Yin C. Prenatal uranium exposure and risk for fetal neural tube defects: A case-control study in women living in a rural area of northern China. J Hazard Mater. 2022 02 15; 424(Pt B):127466.

View in: PubMed
Nassr AA, Hessami K, Shazly SA, Meshinchi N, Corroenne R, Espinoza J, Donepudi R, Sanz Cortes M, Belfort MA, Shamshirsaz AA. Perinatal outcomes of iatrogenic chorioamniotic separation following fetoscopic surgery: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2021 Sep; 58(3):347-353.

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King BC, Hagan J, Corroenne R, Shamshirsaz AA, Espinoza J, Nassr AA, Whitehead W, Belfort MA, Sanz Cortes M. Economic analysis of prenatal fetoscopic vs open-hysterotomy repair of open neural tube defect. Ultrasound Obstet Gynecol. 2021 08; 58(2):230-237.

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Corroenne R, Yepez M, Pyarali M, Fox K, Mastrobattista JM, Mack LM, Lee W, Whitehead WE, Castillo HA, Castillo J, Mehollin-Ray AR, Espinoza J, Shamshirsaz AA, Nassr AA, Belfort MA, Sanz Cortes M. Longitudinal evaluation of motor function in patients who underwent prenatal or postnatal neural tube defect repair. Ultrasound Obstet Gynecol. 2021 08; 58(2):221-229.

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Corroenne R, Sanz Cortes M, Johnson RM, Whitehead WE, Donepudi R, Mehollin-Ray AR, Huisman TAGM, Espinoza J, Nassr AA, Belfort MA, Shamshirsaz AA. Impact of the cystic neural tube defects on fetal motor function in prenatal myelomeningocele repairs: A retrospective cohort study. Prenat Diagn. 2021 Jul; 41(8):965-971.

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Corroenne R, Zarutskie A, Guimaraes C, Yepez M, Torres P, Shetty A, Lee W, Espinoza J, Shamshirsaz AA, Nassr AA, Belfort M, Whitehead W, Sanz Cortes M. Is ventriculomegaly and hindbrain herniation seen before and after prenatal neural tube defect repair associated with a worse functional level than anatomical level at birth? Prenat Diagn. 2021 Jul; 41(8):972-982.

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Liu M, Wang D, Wang C, Yin S, Pi X, Li Z, Wang L, Liu J, Yin C, Jin L, Ren A. High concentrations of aluminum in maternal serum and placental tissue are associated with increased risk for fetal neural tube defects. Chemosphere. 2021 Dec; 284:131387.

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Tian T, Yin S, Jin L, Liu J, Wang C, Wei J, Liu M, Li Z, Wang L, Yin C, Ren A. Single and mixed effects of metallic elements in maternal serum during pregnancy on risk for fetal neural tube defects: A Bayesian kernel regression approach. Environ Pollut. 2021 Sep 15; 285:117203.

View in: PubMed

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