"Thrombopoiesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The humoral factor with thrombopoiesis-stimulating activity is designated THROMBOPOIETIN.
| Descriptor ID |
D034061
|
| MeSH Number(s) |
G04.152.825.798 G09.188.343.798
|
| Concept/Terms |
Thrombopoiesis- Thrombopoiesis
- Thrombopoieses
- Thrombocytopoiesis
- Thrombocytopoieses
|
Below are MeSH descriptors whose meaning is more general than "Thrombopoiesis".
Below are MeSH descriptors whose meaning is more specific than "Thrombopoiesis".
This graph shows the total number of publications written about "Thrombopoiesis" by people in this website by year, and whether "Thrombopoiesis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 0 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thrombopoiesis" by people in Profiles.
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Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice. Arterioscler Thromb Vasc Biol. 2020 10; 40(10):e262-e272.
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Identification of the Regulatory Elements and Target Genes of Megakaryopoietic Transcription Factor MEF2C. Thromb Haemost. 2019 May; 119(5):716-725.
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Pituitary adenylate cyclase-activating polypeptide (PACAP): Differential effects on neonatal vs adult megakaryocytopoiesis. Thromb Res. 2019 Mar; 175:59-60.
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MicroRNA function in megakaryocytes. Platelets. 2019; 30(7):809-816.
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Ocimum flavone Orientin as a countermeasure for thrombocytopenia. Sci Rep. 2018 03 22; 8(1):5075.
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MicroRNAs 10a and 10b Regulate the Expression of Human Platelet Glycoprotein Iba for Normal Megakaryopoiesis. Int J Mol Sci. 2016 Nov 09; 17(11).
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Less Jak2 makes more platelets. Blood. 2014 Oct 02; 124(14):2168-9.
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Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes. Br J Haematol. 2014 Nov; 167(3):337-45.
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Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F-driven mouse model of MPNs. Blood. 2014 Jun 19; 123(25):3943-50.
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The calcineurin-NFAT pathway negatively regulates megakaryopoiesis. Blood. 2013 Apr 18; 121(16):3205-15.