GIULIO DRAETTA to Mutation
This is a "connection" page, showing publications GIULIO DRAETTA has written about Mutation.
Connection Strength
0.425
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The KRAS mutational spectrum and its clinical implications in pancreatic cancer. Cancer Cell. 2024 Sep 09; 42(9):1494-1496.
Score: 0.233
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Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer. Gastroenterology. 2021 07; 161(1):196-210.
Score: 0.046
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Tumors and mitochondrial respiration: a neglected connection. Cancer Res. 2015 Sep 15; 75(18):3685-6.
Score: 0.031
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Mutations at sites involved in Suc1 binding inactivate Cdc2. Mol Cell Biol. 1991 Dec; 11(12):6177-84.
Score: 0.024
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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. J Exp Med. 2007 Aug 06; 204(8):1813-24.
Score: 0.018
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Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis. Science. 2021 Sep 17; 373(6561):eabj0486.
Score: 0.012
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Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib. Cancer Res. 2020 11 01; 80(21):4840-4853.
Score: 0.011
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Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma. Cancer Res. 2019 Nov 01; 79(21):5612-5625.
Score: 0.010
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Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma. Sci Transl Med. 2019 05 08; 11(491).
Score: 0.010
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Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function. Nature. 2014 Oct 30; 514(7524):628-32.
Score: 0.007
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Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src. EMBO J. 1993 Jul; 12(7):2625-34.
Score: 0.007
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Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis. Am J Pathol. 2010 Jul; 177(1):415-23.
Score: 0.005
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Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner. Mol Cell Biol. 2005 Apr; 25(8):3338-47.
Score: 0.004
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p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis. EMBO J. 2001 Dec 03; 20(23):6672-82.
Score: 0.003
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Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases. Am J Pathol. 1998 Sep; 153(3):681-7.
Score: 0.002
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Genetically engineered calmodulins differentially activate target enzymes. J Biol Chem. 1986 Jul 25; 261(21):9896-903.
Score: 0.001