"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
Descriptor ID |
D035683
|
MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 6 | 0 | 6 |
2005 | 10 | 3 | 13 |
2006 | 17 | 2 | 19 |
2007 | 32 | 5 | 37 |
2008 | 62 | 11 | 73 |
2009 | 69 | 12 | 81 |
2010 | 81 | 16 | 97 |
2011 | 97 | 16 | 113 |
2012 | 81 | 18 | 99 |
2013 | 115 | 19 | 134 |
2014 | 116 | 24 | 140 |
2015 | 94 | 22 | 116 |
2016 | 97 | 20 | 117 |
2017 | 75 | 27 | 102 |
2018 | 69 | 19 | 88 |
2019 | 52 | 21 | 73 |
2020 | 47 | 11 | 58 |
2021 | 40 | 16 | 56 |
2022 | 34 | 1 | 35 |
2023 | 41 | 2 | 43 |
2024 | 9 | 0 | 9 |
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Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Alveolar Epithelial Cell Dysfunction in Idiopathic Pulmonary Fibrosis Linked to Lipid Alterations: Therapeutic Implications. Am J Respir Cell Mol Biol. 2024 Apr; 70(4):233-234.
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Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth. Cancer Immunol Immunother. 2024 Mar 30; 73(5):80.
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TGF-?1 and TGF-?R1 variants are associated with clinical outcomes in smoking-related head and neck cancer patients treated with chemoradiation through modulating microRNA-mediated regulation. Cancer Immunol Immunother. 2024 Mar 30; 73(5):85.
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Circulating microRNA Panel for Prediction of Recurrence and Survival in Early-Stage Lung Adenocarcinoma. Int J Mol Sci. 2024 Feb 16; 25(4).
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SPIONs: Superparamagnetic iron oxide-based nanoparticles for the delivery of microRNAi-therapeutics in cancer. Biomed Microdevices. 2024 Feb 07; 26(1):16.
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Tumor-specific polycistronic miRNA delivered by engineered exosomes for the treatment of glioblastoma. Neuro Oncol. 2024 02 02; 26(2):236-250.
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Global miRNA profiling reveals key molecules that contribute to different chronic lymphocytic leukemia incidences in Asian and Western populations. Haematologica. 2024 Feb 01; 109(2):479-492.
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Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity. World J Gastroenterol. 2024 Jan 28; 30(4):332-345.
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Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance. Alzheimers Res Ther. 2024 01 20; 16(1):14.
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miR-142: A Master Regulator in Hematological Malignancies and Therapeutic Opportunities. Cells. 2023 12 30; 13(1).