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THOMAS KOSTEN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Psychiatry & Behavioral Sciences
DivisionPsychiatry & Behavioral Sciences
AddressONE BAYLOR PLAZA
HOUSTON TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pharmacology
    DivisionPharmacology


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    Following a successful 25 year tenure as professor and chief of Psychiatry at Yale University and VA Connecticut, Dr. Kosten joined the Michael E. DeBakey Veterans Affairs Medical Center (MEDVAMC) in July 2006, bringing over 30 years of exemplary Federal service; the majority of which has been with the Department of Veterans Affairs. Over the period 2006-2011, Dr. Kosten served as the Research Director of the VA national Substance Use Disorders Quality Enhancement Research Initiative (QUERI) program, fully revitalizing a research-to-practice implementation program to provide proven, cutting-edge treatment to improve the lives of veteran populations across the VA health care system. With a joint appointment at Baylor College of Medicine (BCM), Dr. Kosten is the JH Waggoner Chair & Professor of Psychiatry, Pharmacology, Neuroscience and Immunology & Pathology. He is also vice-Chair for Psychiatry and Co-director of the Dan L. Duncan Institute for Clinical and Translational Research (ICTR) at Baylor College of Medicine. His other key appointments are Distinguished Professor of Psychiatry at Peking University Medical School and Professor of Epidemiology and of Behavioral Sciences at MD Anderson Cancer Prevention Center. He established the Division of Addictions Psychiatry at Baylor and Yale and directs their NIH Medications Development Center for substance abuse.

    A recognized leader in clinical and translational sciences, Dr. Kosten is a recent past recipient of a Research Scientist Award (1987-2010) from the National Institute of Health (NIH), he has served on national and international review groups for medications and vaccines development in substance abuse, and is credited with the development of several cutting-edge discoveries in medications for addictions. A former Congressional Fellow in the House of Representatives, Dr. Kosten has held visiting professorships in Germany, Spain, Greece, China and Canada. He is the founding vice-chair for Added Qualifications in Addiction Psychiatry of the American Board of Psychiatry and Neurology. He is a distinguished fellow in the American Psychiatric Association and fellow of the American College of Neuropsychopharmacology, past president of the American Academy of Addiction Psychiatry, and past president of the College on Problems of Drug Dependence (CPDD). He has received several prestigious awards for clinical research and for his work in vaccine pharmacotherapy for drug addictions, particularly in treating cocaine, methamphetamine, and opiate addictions. He is the current Editor for the American Journal on Addictions, past Editor for the American Journal of Drug and Alcohol Abuse, and serves on the board of several notable journals in substance abuse. Additionally, Dr. Kosten retains ongoing recognition in the Best Doctors in America® ranking, an honor reserved by only 5% of the nation’s doctors. As of 2012, for the 12th year in a row, he has been named by U.S. News & World Report as a Top Doc®, ranking him among the top 10% of psychiatrists in the region, and for the 9th consecutive year, in the top 1% of psychiatrists in the field of Addictions Medicine. He is a much sought-after expert both nationally and internationally in the field of addictions with appearances on National Geographic, Discovery Channel, and PBS as well as print, radio, and online publications that include WIRED, NPR, and the Wall Street Journal, among others.

    Dr. Kosten’s recent work includes serving on the National Academy of Sciences, Institute of Medicine (IOM) committee on vaccines for substance abuse. He also served on the recently concluded IOM’s Committee on Prevention, Diagnosis, Treatment, and Management of Substance Use Disorders in the U.S. Armed Forces, a congressional mandate via the National Defense Authorization Act for Fiscal Year 2010 (Public Law 111-84), to conduct an independent study on substance use disorders in the military.

    From his studies in substance dependence, post-traumatic stress disorder, and neuroimaging he has published over 600 papers, books and reviews. His medication contributions include a cocaine vaccine, immunotherapy for hallucinogens, buprenorphine for opioid dependence, disulfiram for cocaine dependence, vasodilators for cocaine induced cerebral perfusion defects, and combining medications with contingency management for opioid and cocaine dependence.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mathai DS, Holst M, Rodgman C, Haile CN, Keller J, Hussain MZ, Kosten TR, Newton TF, Verrico CD. Guanfacine Attenuates Adverse Effects of Dronabinol (THC) on Working Memory in Adolescent-Onset Heavy Cannabis Users: A Pilot Study. J Neuropsychiatry Clin Neurosci. 2017 Jun 23; appineuropsych16120328. PMID: 28641496.
      View in: PubMed
    2. Mathai DS, Verrico CD, Shorter D, Coverdale JH, Kosten TR. "Just one bad high:" considering synthetic cannabinoid outcome expectancies in adolescents. Am J Addict. 2016 Oct 17. PMID: 27749024.
      View in: PubMed
    3. Ayanga D, Shorter D, Kosten TR. Update on Pharmacotherapy for Treatment of Opioid Use Disorder. Expert Opin Pharmacother. 2016 Oct 13. PMID: 27734745.
      View in: PubMed
    4. Shorter D, Nielsen DA, Hamon SC, Nielsen EM, Kosten TR, Newton TF, De La Garza R. The ?-1 adrenoceptor (ADRA1A) genotype moderates the magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals. Pharmacogenet Genomics. 2016 Sep; 26(9):428-35. PMID: 27379509; PMCID: PMC4970930 [Available on 09/01/17].
    5. Verrico CD, Haile CN, De La Garza R, Grasing K, Kosten TR, Newton TF. Subjective and Cardiovascular Effects of Intravenous Methamphetamine during Perindopril Maintenance: A Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study. Int J Neuropsychopharmacol. 2016 Jul; 19(7). PMID: 27207905.
      View in: PubMed
    6. Kosten TR, Domingo C. Editorial. Am J Addict. 2016 Jun; 25(4):252-3. PMID: 27232764.
      View in: PubMed
    7. Li X, Shorter D, Kosten TR. Buprenorphine Prescribing: To Expand or Not to Expand. J Psychiatr Pract. 2016 May; 22(3):183-92. PMID: 27123798; PMCID: PMC4852384 [Available on 05/01/17].
    8. Kosten TR. An Opioid for Depression? Am J Psychiatry. 2016 May 1; 173(5):446-7. PMID: 27133402.
      View in: PubMed
    9. Gao Y, Zhou JJ, Zhu Y, Kosten T, Li DP. Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons Through NKCC1 Upregulation. Neuroendocrinology. 2016 Apr 15. PMID: 27077366.
      View in: PubMed
    10. An HM, Tan YL, Tan SP, Shi J, Wang ZR, Yang FD, Huang XF, Soars JC, Kosten TR, Zhang XY. Smoking and Serum Lipid Profiles in Schizophrenia. Neurosci Bull. 2016 Aug; 32(4):383-8. PMID: 27017941.
      View in: PubMed
    11. Xiu MH, Tian L, Chen S, Tan YL, Chen da C, Chen J, Chen N, Yang FD, Licinio J, Kosten TR, Soares JC, Zhang XY. Contribution of IL-10 and its -592 A/C polymorphism to cognitive functions in first-episode drug-naive schizophrenia. Brain Behav Immun. 2016 Oct; 57:116-24. PMID: 26971470.
      View in: PubMed
    12. Zhang XY, Tan YL, Chen DC, Tan SP, Malouta MZ, Bernard JD, Combs JL, Bhatti S, Davis MC, Kosten TR, Soares JC. Serum IL-18 level, clinical symptoms and IL-18-607A/C polymorphism among chronic patients with schizophrenia in a Chinese Han population. Psychoneuroendocrinology. 2016 Jun; 68:140-7. PMID: 26974498.
      View in: PubMed
    13. Zhang XY, Fan FM, Chen DC, Tan YL, Tan SP, Hu K, Salas R, Kosten TR, Zunta-Soares G, Soares JC. Extensive white matter abnormalities and clinical symptoms in drug-naive patients with first-episode schizophrenia: a voxel-based diffusion tensor imaging study. J Clin Psychiatry. 2016 Feb; 77(2):205-11. PMID: 26761708.
      View in: PubMed
    14. Deng H, Wang J, Zhang X, Ma M, Domingo C, Sun H, Kosten T. Smoking reduction and quality of life in chronic patients with schizophrenia in a Chinese population--A pilot study. Am J Addict. 2016 Mar; 25(2):86-90. PMID: 26824336.
      View in: PubMed
    15. Sharp C, Fowler JC, Salas R, Nielsen D, Allen J, Oldham J, Kosten T, Mathew S, Madan A, Frueh BC, Fonagy P. Operationalizing NIMH Research Domain Criteria (RDoC) in naturalistic clinical settings. Bull Menninger Clin. 2016; 80(3):187-212. PMID: 27583809.
      View in: PubMed
    16. Christodoulides N, De La Garza R, Simmons GW, McRae MP, Wong J, Newton TF, Kosten TR, Haque A, McDevitt JT. Next Generation Programmable Bio-Nano-Chip System for On-Site Detection in Oral Fluids. J Drug Abuse. 2015 Nov 23; 1(1):1-6. PMID: 26925466.
      View in: PubMed
    17. Shorter D, Hsieh J, Kosten TR. Pharmacologic management of comorbid post-traumatic stress disorder and addictions. Am J Addict. 2015 Dec; 24(8):705-12. PMID: 26587796.
      View in: PubMed
    18. Haile CN, Kosten TA, Shen XY, O'Malley PW, Winoske KJ, Kinsey BM, Wu Y, Huang Z, Lykissa ED, Naidu N, Cox JA, Arora R, Kosten TR, Orson FM. Altered methamphetamine place conditioning in mice vaccinated with a succinyl-methamphetamine-tetanus-toxoid vaccine. Am J Addict. 2015 Dec; 24(8):748-55. PMID: 26584468.
      View in: PubMed
    19. Zhang XY, Tan YL, Chen DC, Tan SP, Yang FD, Wu HE, Zunta-Soares GB, Huang XF, Kosten TR, Soares JC. Interaction of BDNF with cytokines in chronic schizophrenia. Brain Behav Immun. 2016 Jan; 51:169-75. PMID: 26407757.
      View in: PubMed
    20. Newton TF, Haile CN, Mahoney JJ, Shah R, Verrico CD, De La Garza R, Kosten TR. Dopamine D3 receptor-preferring agonist enhances the subjective effects of cocaine in humans. Psychiatry Res. 2015 Nov 30; 230(1):44-9. PMID: 26239766.
      View in: PubMed
    21. Brewer AJ, Nielsen DA, Spellicy CJ, Hamon SC, Gingrich J, Thompson-Lake DG, Nielsen EM, Mahoney JJ, Kosten TR, Newton TF, De La Garza R. Genetic variation of the dopamine transporter (DAT1) influences the acute subjective responses to cocaine in volunteers with cocaine use disorders. Pharmacogenet Genomics. 2015 Jun; 25(6):296-304. PMID: 25850966; PMCID: PMC4414865.
    22. Christodoulides N, De La Garza R, Simmons GW, McRae MP, Wong J, Newton TF, Smith R, Mahoney Iii JJ, Hohenstein J, Gomez S, Floriano PN, Talavera H, Sloan DJ, Moody DE, Andrenyak DM, Kosten TR, Haque A, McDevitt JT. Application of programmable bio-nano-chip system for the quantitative detection of drugs of abuse in oral fluids. Drug Alcohol Depend. 2015 Aug 1; 153:306-13. PMID: 26048639.
      View in: PubMed
    23. Ma L, Steinberg JL, Cunningham KA, Lane SD, Bjork JM, Neelakantan H, Price AE, Narayana PA, Kosten TR, Bechara A, Moeller FG. Inhibitory behavioral control: A stochastic dynamic causal modeling study comparing cocaine dependent subjects and controls. Neuroimage Clin. 2015; 7:837-47. PMID: 26082893.
      View in: PubMed
    24. Sun Y, Zhao LY, Wang GB, Yue WH, He Y, Shu N, Lin QX, Wang F, Li JL, Chen N, Wang HM, Kosten TR, Feng JJ, Wang J, Tang YD, Liu SX, Deng GF, Diao GH, Tan YL, Han HB, Lin L, Shi J. ZNF804A variants confer risk for heroin addiction and affect decision making and gray matter volume in heroin abusers. Addict Biol. 2016 May; 21(3):657-66. PMID: 25708696.
      View in: PubMed
    25. Cui Y, Robinson JD, Engelmann JM, Lam CY, Minnix JA, Karam-Hage M, Wetter DW, Dani JA, Kosten TR, Cinciripini PM. Reinforcement sensitivity underlying treatment-seeking smokers' affect, smoking reinforcement motives, and affective responses. Psychol Addict Behav. 2015 Jun; 29(2):300-11. PMID: 25621416.
      View in: PubMed
    26. Buda JJ, Carroll FI, Kosten TR, Swearingen D, Walters BB. A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic. Neuropsychopharmacology. 2015 Aug; 40(9):2059-65. PMID: 25628006.
      View in: PubMed
    27. Li QQ, Sun CY, Luo YX, Xue YX, Meng SQ, Xu LZ, Chen N, Deng JH, Zhai HF, Kosten TR, Shi J, Lu L, Sun HQ. A conjugate vaccine attenuates morphine- and heroin-induced behavior in rats. Int J Neuropsychopharmacol. 2015 Mar; 18(5). PMID: 25522425; PMCID: PMC4376548.
    28. Thompson-Lake DG, Cooper KN, Mahoney JJ, Bordnick PS, Salas R, Kosten TR, Dani JA, De La Garza R. Withdrawal Symptoms and Nicotine Dependence Severity Predict Virtual Reality Craving in Cigarette-Deprived Smokers. Nicotine Tob Res. 2015 Jul; 17(7):796-802. PMID: 25475087.
      View in: PubMed
    29. Shorter D, Domingo CB, Kosten TR. Emerging drugs for the treatment of cocaine use disorder: a review of neurobiological targets and pharmacotherapy. Expert Opin Emerg Drugs. 2015 Mar; 20(1):15-29. PMID: 25425416.
      View in: PubMed
    30. Ma L, Steinberg JL, Cunningham KA, Lane SD, Kramer LA, Narayana PA, Kosten TR, Bechara A, Moeller FG. Inhibitory behavioral control: a stochastic dynamic causal modeling study using network discovery analysis. Brain Connect. 2015 Apr; 5(3):177-86. PMID: 25336321; PMCID: PMC4394161.
    31. Kosten TA, Shen XY, Kinsey BM, Kosten TR, Orson FM. Attenuation of cocaine-induced locomotor activity in male and female mice by active immunization. Am J Addict. 2014 Nov-Dec; 23(6):604-7. PMID: 25251469; PMCID: PMC4184912.
    32. Li X, Shorter D, Kosten TR. Buprenorphine in the treatment of opioid addiction: opportunities, challenges and strategies. Expert Opin Pharmacother. 2014 Oct; 15(15):2263-75. PMID: 25171726.
      View in: PubMed
    33. Graham DP, Nielsen DA, Kosten TR, Davis LL, Hamner MB, Makotkine I, Yehuda R. Examining the utility of using genotype and functional biology in a clinical pharmacology trial: pilot testing dopamine ?-hydroxylase, norepinephrine, and post-traumatic stress disorder. Psychiatr Genet. 2014 Aug; 24(4):181-2. PMID: 24983834; PMCID: PMC4080201.
    34. Ramakrishnan M, Kinsey BM, Singh RA, Kosten TR, Orson FM. Hapten optimization for cocaine vaccine with improved cocaine recognition. Chem Biol Drug Des. 2014 Sep; 84(3):354-63. PMID: 24803171; PMCID: PMC4127111.
    35. Liu S, Green CE, Lane SD, Kosten TR, Moeller FG, Nielsen DA, Schmitz JM. The influence of dopamine ?-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence: a preliminary study. Pharmacogenet Genomics. 2014 Jul; 24(7):370-3. PMID: 24809448.
      View in: PubMed
    36. Orson FM, Wang R, Brimijoin S, Kinsey BM, Singh RA, Ramakrishnan M, Wang HY, Kosten TR. The future potential for cocaine vaccines. Expert Opin Biol Ther. 2014 Sep; 14(9):1271-83. PMID: 24835496; PMCID: PMC4154474.
    37. Sun HQ, Chen HM, Yang FD, Lu L, Kosten TR. Epidemiological trends and the advances of treatments of amphetamine-type stimulants (ATS) in China. Am J Addict. 2014 May-Jun; 23(3):313-7. PMID: 24724890.
      View in: PubMed
    38. Kosten TR, Domingo CB, Shorter D, Orson F, Green C, Somoza E, Sekerka R, Levin FR, Mariani JJ, Stitzer M, Tompkins DA, Rotrosen J, Thakkar V, Smoak B, Kampman K. Vaccine for cocaine dependence: a randomized double-blind placebo-controlled efficacy trial. Drug Alcohol Depend. 2014 Jul 1; 140:42-7. PMID: 24793366; PMCID: PMC4073297.
    39. Mancino MJ, McGaugh J, Chopra MP, Guise JB, Cargile C, Williams DK, Thostenson J, Kosten TR, Sanders N, Oliveto A. Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms. J Clin Psychopharmacol. 2014 Apr; 34(2):234-9. PMID: 24525654; PMCID: PMC4068618.
    40. Kosten T, Domingo C, Orson F, Kinsey B. Vaccines against stimulants: cocaine and MA. Br J Clin Pharmacol. 2014 Feb; 77(2):368-74. PMID: 23509915; PMCID: PMC4014030.
    41. Schottenfeld RS, Chawarski MC, Cubells JF, George TP, Lappalainen J, Kosten TR. Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment. Drug Alcohol Depend. 2014 Mar 1; 136:36-42. PMID: 24462581.
      View in: PubMed
    42. Nielsen DA, Hamon SC, Kosten TR. The ?-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial. Psychiatr Genet. 2013 Dec; 23(6):225-32. PMID: 23995774; PMCID: PMC3885873.
    43. Haile CN, Kosten TR. Pharmacotherapy for stimulant-related disorders. Curr Psychiatry Rep. 2013 Nov; 15(11):415. PMID: 24142188; PMCID: PMC3858902.
    44. An HM, Tan YL, Shi J, Wang ZR, Li J, Wang YC, Kosten TR, Zhou DF, Yang FD, Zhang XY. Extract of Ginkgo biloba is equivalent to vitamin E in attenuating and preventing vacuous chewing movements in a rat model of tardive dyskinesia. Behav Pharmacol. 2013 Oct; 24(7):610-6. PMID: 23994817.
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    45. Sun HQ, Chen HM, Yang FD, Lu L, Kosten TR. Epidemiological trends and the advances of treatments of amphetamine-type stimulants (ATS) in China. Am J Addict. 2013 Sep 20. PMID: 24112143.
      View in: PubMed
    46. Verrico CD, Haile CN, Newton TF, Kosten TR, De La Garza R, De La Garza R. Pharmacotherapeutics for substance-use disorders: a focus on dopaminergic medications. Expert Opin Investig Drugs. 2013 Dec; 22(12):1549-68. PMID: 24033127; PMCID: PMC4422382.
    47. Zhang XY, Chen da C, Tan YL, Xiu MH, Cui J, Hui L, De Yang F, Kosten TR. Socio-demographic and clinical characteristics of heavy and non-heavy smokers among schizophrenia inpatients in a Chinese Han population. Psychopharmacology (Berl). 2014 Jan; 231(1):305-14. PMID: 23963531.
      View in: PubMed
    48. Sun H, Wang F, Fan H, Yan Q, Cui K, Yuan W, Zhao F, Zhao L, Yuan J, Yang F, Kosten TR, Zhang XY. The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients. PLoS One. 2013; 8(8):e70963. PMID: 23951054; PMCID: PMC3737228.
    49. Li W, Zhou N, Yu Q, Li X, Yu Y, Sun S, Kou C, Chen da C, Xiu MH, Kosten TR, Zhang XY. Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population. Am J Med Genet B Neuropsychiatr Genet. 2013 Sep; 162B(6):538-45. PMID: 23832605.
      View in: PubMed
    50. Wu JQ, Chen da C, Xiu MH, Tan YL, Yang FD, Kosten TR, Zhang XY. Tardive dyskinesia is associated with greater cognitive impairment in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 1; 46:71-7. PMID: 23827756.
      View in: PubMed
    51. Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA. ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. Pharmacogenet Genomics. 2013 Jul; 23(7):333-40. PMID: 23635803.
      View in: PubMed
    52. Han M, Huang XF, Chen da C, Xiu M, Kosten TR, Zhang XY. Diabetes and cognitive deficits in chronic schizophrenia: a case-control study. PLoS One. 2013; 8(6):e66299. PMID: 23840437; PMCID: PMC3688788.
    53. Zhang XY, Al Jurdi RK, Zoghbi AW, Chen da C, Xiu MH, Tan YL, Yang FD, Kosten TR. Prevalence, demographic and clinical correlates of suicide attempts in Chinese medicated chronic inpatients with schizophrenia. J Psychiatr Res. 2013 Oct; 47(10):1370-5. PMID: 23791457.
      View in: PubMed
    54. Kosten TA, Shen XY, O'Malley PW, Kinsey BM, Lykissa ED, Orson FM, Kosten TR. A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1; 45:223-9. PMID: 23739535; PMCID: PMC3773503.
    55. Hui L, Zhang X, Yu YQ, Han M, Huang XF, Chen da C, Wang ZR, Du WL, Kou CG, Yu Q, Kosten TR, Zhang XY. Association between DBH 19 bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients. Schizophr Res. 2013 Jul; 147(2-3):236-40. PMID: 23707643.
      View in: PubMed
    56. Krupitsky E, Zvartau E, Blokhina E, Verbitskaya E, Tsoy M, Wahlgren V, Burakov A, Masalov D, Romanova TN, Palatkin V, Tyurina A, Yaroslavtseva T, Sinha R, Kosten TR. Naltrexone with or without guanfacine for preventing relapse to opiate addiction in St.-Petersburg, Russia. Drug Alcohol Depend. 2013 Oct 1; 132(3):674-80. PMID: 23683793; PMCID: PMC3971535.
    57. Zhang XY, Chen da C, Xiu MH, Tan YL, Yang FD, Zhang LY, Zhang LY, Haile CN, Kosten TR. Clinical symptoms and cognitive impairment associated with male schizophrenia relate to plasma manganese superoxide dismutase activity: a case-control study. J Psychiatr Res. 2013 Aug; 47(8):1049-53. PMID: 23611682.
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    58. Kosten TR, Domingo CB. Can you vaccinate against substance abuse? Expert Opin Biol Ther. 2013 Aug; 13(8):1093-7. PMID: 23594123; PMCID: PMC4154471.
    59. Zhang XY, Chen da C, Xiu MH, Yang FD, Tan Y, Luo X, Zuo L, Kosten TA, Kosten TR. Cognitive function, plasma MnSOD activity, and MnSOD Ala-9Val polymorphism in patients with schizophrenia and normal controls. Schizophr Bull. 2014 May; 40(3):592-601. PMID: 23588476; PMCID: PMC3984504.
    60. Zhou N, Yu Q, Li X, Yu Y, Kou C, Li W, Xu H, Luo X, Zuo L, Kosten TR, Zhang XY. Association of the dopamine ?-hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Hum Psychopharmacol. 2013 May; 28(3):230-7. PMID: 23559427.
      View in: PubMed
    61. Zhang X, Hui L, Liu Y, Wang ZQ, You Y, Miao LN, Sun SL, Guan SL, Xiang Y, Kosten TR, Zhang XY. The type 2 diabetes mellitus susceptibility gene IGF2BP2 is associated with schizophrenia in a Han Chinese population. J Clin Psychiatry. 2013 Apr; 74(4):e287-92. PMID: 23656854.
      View in: PubMed
    62. Zhang XY, Tang W, Xiu MH, Chen da C, Yang FD, Tan YL, Wang ZR, Zhang F, Liu J, Liu L, Chen Y, Wen N, Kosten TR. Interleukin 18 and cognitive impairment in first episode and drug naïve schizophrenia versus healthy controls. Brain Behav Immun. 2013 Aug; 32:105-11. PMID: 23499732.
      View in: PubMed
    63. Graham DP, Helmer DA, Harding MJ, Kosten TR, Petersen NJ, Nielsen DA. Serotonin transporter genotype and mild traumatic brain injury independently influence resilience and perception of limitations in veterans. J Psychiatr Res. 2013 Jun; 47(6):835-42. PMID: 23478049; PMCID: PMC3643301.
    64. Wu JQ, Kosten TR, Zhang XY. Free radicals, antioxidant defense systems, and schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 1; 46:200-6. PMID: 23470289.
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    65. Brimijoin S, Shen X, Orson F, Kosten T. Prospects, promise and problems on the road to effective vaccines and related therapies for substance abuse. Expert Rev Vaccines. 2013 Mar; 12(3):323-32. PMID: 23496671; PMCID: PMC3738206.
    66. Brown AE, Tonigan JS, Pavlik VN, Kosten TR, Volk RJ. Spirituality and confidence to resist substance use among celebrate recovery participants. J Relig Health. 2013 Mar; 52(1):107-13. PMID: 21246280.
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    67. Kosten TR, Domingo CB, Hamon SC, Nielsen DA. DBH gene as predictor of response in a cocaine vaccine clinical trial. Neurosci Lett. 2013 Apr 29; 541:29-33. PMID: 23458673; PMCID: PMC3631430.
    68. Orson FM, Rossen RD, Shen X, Lopez AY, Wu Y, Kosten TR. Spontaneous development of IgM anti-cocaine antibodies in habitual cocaine users: effect on IgG antibody responses to a cocaine cholera toxin B conjugate vaccine. Am J Addict. 2013 Mar-Apr; 22(2):169-74. PMID: 23414504; PMCID: PMC4143984.
    69. Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA. The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency. Front Psychiatry. 2012; 3:109. PMID: 23335901; PMCID: PMC3544007.
    70. Zhang XY, Chen da C, Xiu MH, Luo X, Zuo L, Haile CN, Kosten TA, Kosten TR. BDNF Val66Met variant and smoking in a Chinese population. PLoS One. 2012; 7(12):e53295. PMID: 23285275; PMCID: PMC3532294.
    71. Zhen YF, Zhang J, Liu XY, Fang H, Tian LB, Zhou DH, Kosten TR, Zhang XY. Low BDNF is associated with cognitive deficits in patients with type 2 diabetes. Psychopharmacology (Berl). 2013 May; 227(1):93-100. PMID: 23263460.
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    72. Zhang XY, Chen da C, Xiu MH, Yang FD, Tan YL, He S, Kosten TA, Kosten TR. Thioredoxin, a novel oxidative stress marker and cognitive performance in chronic and medicated schizophrenia versus healthy controls. Schizophr Res. 2013 Feb; 143(2-3):301-6. PMID: 23238053.
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    73. He J, Xie Y, Tao J, Su H, Wu W, Zou S, Zhang J, Zhang J, Zhang H, Yang X, Guo J, Tang W, Zhang F, Liu J, Liu L, Chen Y, Wen N, Kosten TR, Zhang XY. Gender differences in socio-demographic and clinical characteristics of methamphetamine inpatients in a Chinese population. Drug Alcohol Depend. 2013 Jun 1; 130(1-3):94-100. PMID: 23149112.
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    74. Haile CN, De La Garza R, Mahoney JJ, Nielsen DA, Kosten TR, Newton TF. The impact of disulfiram treatment on the reinforcing effects of cocaine: a randomized clinical trial. PLoS One. 2012; 7(11):e47702. PMID: 23144826; PMCID: PMC3493584.
    75. Cui Y, Versace F, Engelmann JM, Minnix JA, Robinson JD, Lam CY, Karam-Hage M, Brown VL, Wetter DW, Dani JA, Kosten TR, Cinciripini PM. Alpha oscillations in response to affective and cigarette-related stimuli in smokers. Nicotine Tob Res. 2013 May; 15(5):917-24. PMID: 23060019; PMCID: PMC3621581.
    76. Shen XY, Kosten TA, Lopez AY, Kinsey BM, Kosten TR, Orson FM. A vaccine against methamphetamine attenuates its behavioral effects in mice. Drug Alcohol Depend. 2013 Apr 1; 129(1-2):41-8. PMID: 23022610; PMCID: PMC3563850.
    77. Zhang XY, Liu L, Liu S, Hong X, Chen da C, Xiu MH, Yang FD, Zhang Z, Zhang X, Kosten TA, Kosten TR. Short-term tropisetron treatment and cognitive and P50 auditory gating deficits in schizophrenia. Am J Psychiatry. 2012 Sep; 169(9):974-81. PMID: 22952075.
      View in: PubMed
    78. Brimijoin S, Orson F, Kosten TR, Kinsey B, Shen XY, White SJ, Gao Y. Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice. Chem Biol Interact. 2013 Mar 25; 203(1):212-6. PMID: 22960160; PMCID: PMC3572300.
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    84. Zhang X, Guan SL, Wang ZQ, You Y, Sun SL, Hui L, Miao LN, Yu Y, Kosten TR, Zhang XY. No association between the type 2 diabetes mellitus susceptibility gene, SLC30A8 and schizophrenia in a Chinese population. Hum Psychopharmacol. 2012 Jul; 27(4):392-6. PMID: 22778022.
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    95. Zhang XY, Chen da C, Xiu MH, Haile CN, Luo X, Xu K, Zhang HP, Zuo L, Zhang Z, Zhang X, Kosten TA, Kosten TR. Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls. Hum Genet. 2012 Jul; 131(7):1187-95. PMID: 22362486; PMCID: PMC3671849.
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    97. Cui Y, Robinson JD, Versace F, Lam CY, Minnix JA, Karam-Hage M, Dani JA, Kosten TR, Wetter DW, Brown VL, Cinciripini PM. Differential cigarette-related startle cue reactivity among light, moderate, and heavy smokers. Addict Behav. 2012 Aug; 37(8):885-9. PMID: 22571920; PMCID: PMC3358408.
    98. Zhang XY, Liang J, Chen da C, Xiu MH, He J, Cheng W, Wu Z, Yang FD, Haile CN, Sun H, Lu L, Kosten TA, Kosten TR. Cigarette smoking in male patients with chronic schizophrenia in a Chinese population: prevalence and relationship to clinical phenotypes. PLoS One. 2012; 7(2):e30937. PMID: 22347412; PMCID: PMC3274516.
    99. Newton TF, De La Garza R, Brown G, Kosten TR, Mahoney JJ, Haile CN. Noradrenergic ?? receptor antagonist treatment attenuates positive subjective effects of cocaine in humans: a randomized trial. PLoS One. 2012; 7(2):e30854. PMID: 22319592; PMCID: PMC3272014.
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    102. Wang F, Fan H, Sun H, Yang F, Luo Y, Liu H, Kosten TR, Lu L, Zhang XY. Association between TNF-? promoter -308A/G polymorphism and tardive dyskinesian Chinese Han patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2012 Apr 27; 37(1):106-10. PMID: 22227290.
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    103. Shorter D, Kosten TR. Vaccines in the Treatment of Substance Abuse. Focus (Am Psychiatr Publ). 2011 Dec 01; 2011(9):25-30. PMID: 23472050.
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    106. Shorter D, Kosten TR. Novel pharmacotherapeutic treatments for cocaine addiction. BMC Med. 2011; 9:119. PMID: 22047090; PMCID: PMC3216852.
    107. Oliveto A, Poling J, Mancino MJ, Williams DK, Thostenson J, Pruzinsky R, Gonsai K, Sofuoglu M, Gonzalez G, Tripathi S, Kosten TR. Sertraline delays relapse in recently abstinent cocaine-dependent patients with depressive symptoms. Addiction. 2012 Jan; 107(1):131-41. PMID: 21707811; PMCID: PMC3237722.
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    109. Anton RF, Litten RZ, Falk DE, Palumbo JM, Bartus RT, Robinson RL, Kranzler HR, Kosten TR, Meyer RE, O'Brien CP, Mann K, Meulien D. The Alcohol Clinical Trials Initiative (ACTIVE): purpose and goals for assessing important and salient issues for medications development in alcohol use disorders. Neuropsychopharmacology. 2012 Jan; 37(2):402-11. PMID: 21900883; PMCID: PMC3242301.
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    111. Yang YQ, Sun S, Yu YQ, Li WJ, Zhang X, Xiu MH, Chen DC, De Yang F, Liu H, Li C, Kosten TR, Zhang XY. Decreased serum brain-derived neurotrophic factor levels in schizophrenic patients with tardive dyskinesia. Neurosci Lett. 2011 Sep 8; 502(1):37-40. PMID: 21798311.
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    117. McIntosh BJ, Zhang XY, Kosten T, Tan SP, Xiu MH, Rakofsky J, Harvey PD. Performance-based assessment of functional skills in severe mental illness: results of a large-scale study in China. J Psychiatr Res. 2011 Aug; 45(8):1089-94. PMID: 21300378; PMCID: PMC3112265.
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    119. Cao JX, Hu J, Ye XM, Xia Y, Haile CA, Kosten TR, Zhang XY. Association between the 5-HTR1B gene polymorphisms and alcohol dependence in a Han Chinese population. Brain Res. 2011 Feb 28; 1376:1-9. PMID: 21172311.
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    120. Kinsey BM, Kosten TR, Orson FM. Anti-cocaine vaccine development. Expert Rev Vaccines. 2010 Sep; 9(9):1109-14. PMID: 20822352; PMCID: PMC2936703.
    121. Li SX, Liu LJ, Jiang WG, Sun LL, Zhou SJ, Le Foll B, Zhang XY, Kosten TR, Lu L. Circadian alteration in neurobiology during protracted opiate withdrawal in rats. J Neurochem. 2010 Oct; 115(2):353-62. PMID: 20738730.
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    122. Chen DC, Zhou MA, Zhou DH, Xiu MH, Wu GY, Kosten TR, Zhang XY. Gender differences in the prevalence of diabetes mellitus in chronic hospitalized patients with schizophrenia on long-term antipsychotics. Psychiatry Res. 2011 Apr 30; 186(2-3):451-3. PMID: 20797801.
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    123. Oliveto A, Gentry WB, Pruzinsky R, Gonsai K, Kosten TR, Martell B, Poling J. Behavioral effects of gamma-hydroxybutyrate in humans. Behav Pharmacol. 2010 Jul; 21(4):332-42. PMID: 20526195; PMCID: PMC2911496.
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    125. Najavits LM, Norman SB, Kivlahan D, Kosten TR. Improving PTSD/substance abuse treatment in the VA: a survey of providers. Am J Addict. 2010 May-Jun; 19(3):257-63. PMID: 20525033.
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    129. Kinsey BM, Kosten TR, Orson FM. Active immunotherapy for the Treatment of Cocaine Dependence. Drugs Future. 2010 Apr 1; 35(4):301-306. PMID: 21796226.
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    132. Haile CN, Kosten TR. The potential of pharmacogenomics to treat drug addiction. Pharmacogenomics. 2009 Dec; 10(12):1883-6. PMID: 19958085.
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    140. Chen JX, Su YA, Wang SL, Bian QT, Liu YH, Wang N, Yang FD, Haile C, Kosten TR, Zhang XY. Aripiprazole treatment of risperidone-induced hyperprolactinemia. J Clin Psychiatry. 2009 Jul; 70(7):1058-9. PMID: 19653986.
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    145. Shi J, Jun W, Zhao LY, Xue YX, Zhang XY, Kosten TR, Lu L. Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts. Eur J Pharmacol. 2009 Aug 1; 615(1-3):108-12. PMID: 19470385.
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    150. Sofuoglu M, Poling J, Hill K, Kosten T. Atomoxetine attenuates dextroamphetamine effects in humans. Am J Drug Alcohol Abuse. 2009; 35(6):412-6. PMID: 20014909; PMCID: PMC2796580.
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    152. Lu L, Wang X, Kosten TR. Stereotactic neurosurgical treatment of drug addiction. Am J Drug Alcohol Abuse. 2009; 35(6):391-3. PMID: 20014906.
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    153. Sun HQ, Guo S, Chen DF, Jiang ZN, Liu Y, Di XL, Yang FD, Zhang XY, Kosten TR, Lu L. Family support and employment as predictors of smoking cessation success: a randomized, double-blind, placebo-controlled trial of nicotine sublingual tablets in chinese smokers. Am J Drug Alcohol Abuse. 2009; 35(3):183-8. PMID: 19462302.
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    175. Poling J, Pruzinsky R, Kosten TR, Gonsai K, Sofuoglu M, Gonzalez G, Oliveto A. Clinical efficacy of citalopram alone or augmented with bupropion in methadone-stabilized patients. Am J Addict. 2007 May-Jun; 16(3):187-94. PMID: 17612822.
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    176. Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Haile CN, Kosten TA, Kosten TR. Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia. J Clin Psychiatry. 2007 May; 68(5):754-60. PMID: 17503985.
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    177. Kleber HD, Weiss RD, Anton RF, George TP, Greenfield SF, Kosten TR, O'Brien CP, Rounsaville BJ, Strain EC, Ziedonis DM, Hennessy G, Connery HS, McIntyre JS, Charles SC, Anzia DJ, Cook IA, Finnerty MT, Johnson BR, Nininger JE, Summergrad P, Woods SM, Yager J, Pyles R, Cross CD, Peele R, Shemo JP, Lurie L, Walker RD, Barnovitz MA, Gray SH, Saxena S, Tonnu T, Kunkle R, Albert AB, Fochtmann LJ, Hart C, Regier D. Treatment of patients with substance use disorders, second edition. American Psychiatric Association. Am J Psychiatry. 2007 Apr; 164(4 Suppl):5-123. PMID: 17569411.
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    178. Zhang XY, Tan YL, Zhou DF, Haile CN, Wu GY, Cao LY, Kosten TA, Kosten TR. Nicotine dependence, symptoms and oxidative stress in male patients with schizophrenia. Neuropsychopharmacology. 2007 Sep; 32(9):2020-4. PMID: 17228336.
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    179. Martell BA, O'Connor PG, Kerns RD, Becker WC, Morales KH, Kosten TR, Fiellin DA. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Ann Intern Med. 2007 Jan 16; 146(2):116-27. PMID: 17227935.
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    180. Guo S, Chen DF, Zhou DF, Sun HQ, Wu GY, Haile CN, Kosten TA, Kosten TR, Zhang XY. Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. Psychopharmacology (Berl). 2007 Mar; 190(4):449-56. PMID: 17206495.
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    181. Lane SD, Moeller FG, Steinberg JL, Buzby M, Kosten TR. Performance of cocaine dependent individuals and controls on a response inhibition task with varying levels of difficulty. Am J Drug Alcohol Abuse. 2007; 33(5):717-26. PMID: 17891664.
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    182. Kosten TR. Pharmacotherapy for addictions: partnering with contingency management. Am J Drug Alcohol Abuse. 2007; 33(3):341-2. PMID: 17613962.
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    183. Poling J, Kosten TR, Sofuoglu M. Treatment outcome predictors for cocaine dependence. Am J Drug Alcohol Abuse. 2007; 33(2):191-206. PMID: 17497542.
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    184. Gardner TJ, Kosten TR. Human laboratory and neuroimaging studies in substance use disorders: developing new treatment approaches. Am J Drug Alcohol Abuse. 2007; 33(6):765-7. PMID: 17994472.
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    185. Brown AE, Pavlik VN, Shegog R, Whitney SN, Friedman LC, Romero C, Davis GC, Cech I, Kosten TR, Volk RJ. Association of spirituality and sobriety during a behavioral spirituality intervention for Twelve Step (TS) recovery. Am J Drug Alcohol Abuse. 2007; 33(4):611-7. PMID: 17668347.
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    186. Gardner TJ, Kosten TR. Therapeutic options and challenges for substances of abuse. Dialogues Clin Neurosci. 2007; 9(4):431-45. PMID: 18286802; PMCID: PMC3202509.
    187. Gardner TJ, Kosten TR. Pharmacotherapeutic environments for substance use disorders. Am J Drug Alcohol Abuse. 2007; 33(5):627-9. PMID: 17891655.
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    188. Sinha R, Kimmerling A, Doebrick C, Kosten TR. Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. Psychopharmacology (Berl). 2007 Mar; 190(4):569-74. PMID: 17136399.
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    189. Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Xu Q, Shen Y, Haile CN, Kosten TA, Kosten TR. Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. J Psychiatr Res. 2007 Dec; 41(12):997-1004. PMID: 17095017.
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    190. Haile CN, Kosten TR, Kosten TA. Genetics of dopamine and its contribution to cocaine addiction. Behav Genet. 2007 Jan; 37(1):119-45. PMID: 17063402.
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    191. González G, Desai R, Sofuoglu M, Poling J, Oliveto A, Gonsai K, Kosten TR. Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. Drug Alcohol Depend. 2007 Feb 23; 87(1):1-9. PMID: 16930857.
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    192. Kosten TR, Scanley BE, Tucker KA, Oliveto A, Prince C, Sinha R, Potenza MN, Skudlarski P, Wexler BE. Cue-induced brain activity changes and relapse in cocaine-dependent patients. Neuropsychopharmacology. 2006 Mar; 31(3):644-50. PMID: 16123763.
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    193. Sofuoglu M, Kosten TR. Emerging pharmacological strategies in the fight against cocaine addiction. Expert Opin Emerg Drugs. 2006 Mar; 11(1):91-8. PMID: 16503828.
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    194. Li CS, Kosten TR, Sinha R. Antisocial personality and stress-induced brain activation in cocaine-dependent patients. Neuroreport. 2006 Feb 27; 17(3):243-7. PMID: 16462591.
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    195. Poling J, Oliveto A, Petry N, Sofuoglu M, Gonsai K, Gonzalez G, Martell B, Kosten TR. Six-month trial of bupropion with contingency management for cocaine dependence in a methadone-maintained population. Arch Gen Psychiatry. 2006 Feb; 63(2):219-28. PMID: 16461866.
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    196. Sofuoglu M, Poling J, Mouratidis M, Kosten T. Effects of topiramate in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2006 Mar; 184(3-4):645-51. PMID: 16432681.
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    197. Sofuoglu M, Poling J, Gonzalez G, Gonsai K, Kosten T. Cocaine withdrawal symptoms predict medication response in cocaine users. Am J Drug Alcohol Abuse. 2006; 32(4):617-27. PMID: 17127550.
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    198. Sofuoglu M, Poling J, Mitchell E, Kosten TR. Tiagabine affects the subjective responses to cocaine in humans. Pharmacol Biochem Behav. 2005 Nov; 82(3):569-73. PMID: 16332385.
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    199. Sinha R, Lacadie C, Skudlarski P, Fulbright RK, Rounsaville BJ, Kosten TR, Wexler BE. Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study. Psychopharmacology (Berl). 2005 Dec; 183(2):171-80. PMID: 16163517.
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    200. Sofuoglu M, Mouratidis M, Yoo S, Culligan K, Kosten T. Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2005 Sep; 181(3):504-10. PMID: 15983800.
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    201. Kosten T, Owens SM. Immunotherapy for the treatment of drug abuse. Pharmacol Ther. 2005 Oct; 108(1):76-85. PMID: 16023218.
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    202. Oliveto A, Poling J, Sevarino KA, Gonsai KR, McCance-Katz EF, Stine SM, Kosten TR. Efficacy of dose and contingency management procedures in LAAM-maintained cocaine-dependent patients. Drug Alcohol Depend. 2005 Aug 1; 79(2):157-65. PMID: 16002025.
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    203. Martell BA, Mitchell E, Poling J, Gonsai K, Kosten TR. Vaccine pharmacotherapy for the treatment of cocaine dependence. Biol Psychiatry. 2005 Jul 15; 58(2):158-64. PMID: 16038686.
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    204. Kosten TR. What are America's opportunities for harm reduction strategies in opiate dependence? Am J Addict. 2005 Jul-Sep; 14(4):307-10. PMID: 16188710.
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    205. Boutros NN, Lisanby SH, McClain-Furmanski D, Oliwa G, Gooding D, Kosten TR. Cortical excitability in cocaine-dependent patients: a replication and extension of TMS findings. J Psychiatr Res. 2005 May; 39(3):295-302. PMID: 15725428.
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    206. Abi-Saab D, Beauvais J, Mehm J, Brody M, Gottschalk C, Kosten TR. The effect of alcohol on the neuropsychological functioning of recently abstinent cocaine-dependent subjects. Am J Addict. 2005 Mar-Apr; 14(2):166-78. PMID: 16019965.
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    207. Li CS, Kosten TR, Sinha R. Sex differences in brain activation during stress imagery in abstinent cocaine users: a functional magnetic resonance imaging study. Biol Psychiatry. 2005 Mar 1; 57(5):487-94. PMID: 15737663.
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    208. Schottenfeld RS, Chawarski MC, Pakes JR, Pantalon MV, Carroll KM, Kosten TR. Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence. Am J Psychiatry. 2005 Feb; 162(2):340-9. PMID: 15677600.
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    209. Kosten TR. Future of anti-addiction vaccines. Stud Health Technol Inform. 2005; 118:177-85. PMID: 16301778.
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    210. Kosten T, Sofuoglu M, Poling J, Gonsai K, Oliveto A. Desipramine treatment for cocaine dependence in buprenorphine- or methadone-treated patients: baseline urine results as predictor of response. Am J Addict. 2005 Jan-Feb; 14(1):8-17. PMID: 15804873.
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    211. Sofuoglu M, Kosten TR. Novel approaches to the treatment of cocaine addiction. CNS Drugs. 2005; 19(1):13-25. PMID: 15651902.
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    212. Sofuoglu M, Kosten TR. Pharmacologic management of relapse prevention in addictive disorders. Psychiatr Clin North Am. 2004 Dec; 27(4):627-48. PMID: 15550284.
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    213. O'Brien CP, Charney DS, Lewis L, Cornish JW, Post RM, Woody GE, Zubieta JK, Anthony JC, Blaine JD, Bowden CL, Calabrese JR, Carroll K, Kosten T, Rounsaville B, Childress AR, Oslin DW, Pettinati HM, Davis MA, Demartino R, Drake RE, Fleming MF, Fricks L, Glassman AH, Levin FR, Nunes EV, Johnson RL, Jordan C, Kessler RC, Laden SK, Regier DA, Renner JA, Ries RK, Sklar-Blake T, Weisner C. Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action. Biol Psychiatry. 2004 Nov 15; 56(10):703-13. PMID: 15556110.
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    214. Kosten TR, Kosten TA. New medication strategies for comorbid substance use and bipolar affective disorders. Biol Psychiatry. 2004 Nov 15; 56(10):771-7. PMID: 15556122.
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    215. Fiellin DA, Kleber H, Trumble-Hejduk JG, McLellan AT, Kosten TR. Consensus statement on office-based treatment of opioid dependence using buprenorphine. J Subst Abuse Treat. 2004 Sep; 27(2):153-9. PMID: 15450648.
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    216. Carroll KM, Kosten TR, Rounsaville BJ. Choosing a behavioral therapy platform for pharmacotherapy of substance users. Drug Alcohol Depend. 2004 Aug 16; 75(2):123-34. PMID: 15276217; PMCID: PMC3668430.
    217. Sofuoglu M, Mitchell E, Kosten TR. Effects of progesterone treatment on cocaine responses in male and female cocaine users. Pharmacol Biochem Behav. 2004 Aug; 78(4):699-705. PMID: 15301924.
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    218. Oliveto A, Poling J, Kosten TR, Gonsai K. Isradipine and dextromethorphan in methadone-maintained humans under a naloxone discrimination procedure. Eur J Pharmacol. 2004 May 3; 491(2-3):157-68. PMID: 15140632.
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    219. Tucker KA, Browndyke JN, Gottschalk PC, Cofrancesco AT, Kosten TR. Gender-specific vulnerability for rCBF abnormalities among cocaine abusers. Neuroreport. 2004 Apr 9; 15(5):797-801. PMID: 15073517.
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    220. Gonzalez G, Oliveto A, Kosten TR. Combating opiate dependence: a comparison among the available pharmacological options. Expert Opin Pharmacother. 2004 Apr; 5(4):713-25. PMID: 15102558.
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    221. Haney M, Kosten TR. Therapeutic vaccines for substance dependence. Expert Rev Vaccines. 2004 Feb; 3(1):11-8. PMID: 14761239.
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    222. West JC, Kosten TR, Wilk J, Svikis D, Triffleman E, Rae DS, Narrow WE, Duffy FF, Regier DA. Challenges in increasing access to buprenorphine treatment for opiate addiction. Am J Addict. 2004; 13 Suppl 1:S8-16. PMID: 15204672.
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    223. Kosten TR, Tucker K, Gottschalk PC, Rinder CS, Rinder HM. Platelet abnormalities associated with cerebral perfusion defects in cocaine dependence. Biol Psychiatry. 2004 Jan 1; 55(1):91-7. PMID: 14706430.
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    224. Kosten TR, Fiellin DA. Buprenorphine for office-based practice: consensus conference overview. Am J Addict. 2004; 13 Suppl 1:S1-7. PMID: 15204671.
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    225. Haile CN, During MJ, Jatlow PI, Kosten TR, Kosten TA. Disulfiram facilitates the development and expression of locomotor sensitization to cocaine in rats. Biol Psychiatry. 2003 Nov 1; 54(9):915-21. PMID: 14573319.
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    226. Gonzalez G, Sevarino K, Sofuoglu M, Poling J, Oliveto A, Gonsai K, George TP, Kosten TR. Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. Addiction. 2003 Nov; 98(11):1625-32. PMID: 14616189.
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    227. Kosten TR, Gottschalk PC, Tucker K, Rinder CS, Dey HM, Rinder HM. Aspirin or amiloride for cerebral perfusion defects in cocaine dependence. Drug Alcohol Depend. 2003 Aug 20; 71(2):187-94. PMID: 12927657.
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    228. Gonzalez G, Feingold A, Oliveto A, Gonsai K, Kosten TR. Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management. Am J Drug Alcohol Abuse. 2003 Aug; 29(3):497-514. PMID: 14510037.
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    229. Oliveto A, Benios T, Gonsai K, Feingold A, Poling J, Kosten TR. D-cycloserine-Naloxone interactions in opioid-dependent humans under a novel-response naloxone discrimination procedure. Exp Clin Psychopharmacol. 2003 Aug; 11(3):237-46. PMID: 12940503.
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    230. Sofuoglu M, Singha A, Kosten TR, McCance-Katz FE, Petrakis I, Oliveto A. Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans. Pharmacol Biochem Behav. 2003 Jul; 75(4):801-8. PMID: 12957222.
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    231. Reid MC, Tinetti ME, O'Connor PG, Kosten TR, Concato J. Measuring alcohol consumption among older adults: a comparison of available methods. Am J Addict. 2003 May-Jun; 12(3):211-9. PMID: 12851017.
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    232. Kosten TR, O'Connor PG. Management of drug and alcohol withdrawal. N Engl J Med. 2003 May 1; 348(18):1786-95. PMID: 12724485.
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    233. George TP, Vessicchio JC, Termine A, Jatlow PI, Kosten TR, O'Malley SS. A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation. Biol Psychiatry. 2003 Jan 15; 53(2):136-43. PMID: 12547469.
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    234. Sofuoglu M, Gonzalez G, Poling J, Kosten TR. Prediction of treatment outcome by baseline urine cocaine results and self-reported cocaine use for cocaine and opioid dependence. Am J Drug Alcohol Abuse. 2003; 29(4):713-27. PMID: 14713135.
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    235. Kosten TR, Biegel D. Therapeutic vaccines for substance dependence. Expert Rev Vaccines. 2002 Oct; 1(3):363-71. PMID: 12901575.
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    236. Gottschalk PC, Kosten TR. Cerebral perfusion defects in combined cocaine and alcohol dependence. Drug Alcohol Depend. 2002 Sep 1; 68(1):95-104. PMID: 12167555.
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    237. George TP, Vessicchio JC, Termine A, Bregartner TA, Feingold A, Rounsaville BJ, Kosten TR. A placebo controlled trial of bupropion for smoking cessation in schizophrenia. Biol Psychiatry. 2002 Jul 1; 52(1):53-61. PMID: 12079730.
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    238. Kosten TR, George TP. The neurobiology of opioid dependence: implications for treatment. Sci Pract Perspect. 2002 Jul; 1(1):13-20. PMID: 18567959; PMCID: PMC2851054.
    239. Stine SM, Southwick SM, Petrakis IL, Kosten TR, Charney DS, Krystal JH. Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients. Biol Psychiatry. 2002 Apr 15; 51(8):642-51. PMID: 11955464.
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    240. Boutros NN, Gelernter J, Gooding DC, Cubells J, Young A, Krystal JH, Kosten T. Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data. Biol Psychiatry. 2002 Apr 15; 51(8):683-6. PMID: 11955469.
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    241. Kosten TR, Oliveto A, Sevarino KA, Gonsai K, Feingold A. Ketoconazole increases cocaine and opioid use in methadone maintained patients. Drug Alcohol Depend. 2002 Apr 1; 66(2):173-80. PMID: 11906804.
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    242. Kosten TR, George TP, Kosten TA. The potential of dopamine agonists in drug addiction. Expert Opin Investig Drugs. 2002 Apr; 11(4):491-9. PMID: 11922858.
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    243. Kosten TR, Rosen M, Bond J, Settles M, Roberts JS, Shields J, Jack L, Fox B. Human therapeutic cocaine vaccine: safety and immunogenicity. Vaccine. 2002 Jan 15; 20(7-8):1196-204. PMID: 11803082.
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    244. George TP, Vessicchio JC, Termine A, Sahady DM, Head CA, Pepper WT, Kosten TR, Wexler BE. Effects of smoking abstinence on visuospatial working memory function in schizophrenia. Neuropsychopharmacology. 2002 Jan; 26(1):75-85. PMID: 11751034.
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    245. Feingold A, Oliveto A, Schottenfeld R, Kosten TR. Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers. Am J Addict. 2002; 11(2):111-23. PMID: 12028741.
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    246. Gonzalez G, Oliveto A, Kosten TR. Treatment of heroin (diamorphine) addiction: current approaches and future prospects. Drugs. 2002; 62(9):1331-43. PMID: 12076182.
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    247. Kosten TR, Gorelick DA. The Lexington narcotic farm. Am J Psychiatry. 2002 Jan; 159(1):22. PMID: 11772684.
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    248. Gottschalk PC, Kosten TR. Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. Am J Addict. 2002; 11(3):200-8. PMID: 12202012.
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    249. Jacobsen LK, Southwick SM, Kosten TR. Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. Am J Psychiatry. 2001 Aug; 158(8):1184-90. PMID: 11481147.
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    250. Fiellin DA, Rosenheck RA, Kosten TR. Office-based treatment for opioid dependence: reaching new patient populations. Am J Psychiatry. 2001 Aug; 158(8):1200-4. PMID: 11481150.
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    251. Rosenheck R, Kosten T. Buprenorphine for opiate addiction: potential economic impact. Drug Alcohol Depend. 2001 Aug 1; 63(3):253-62. PMID: 11418229.
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    252. Oliveto A, McCance-Katz FE, Singha A, Petrakis I, Hameedi F, Kosten TR. Effects of cocaine prior to and during bupropion maintenance in cocaine-abusing volunteers. Drug Alcohol Depend. 2001 Jul 1; 63(2):155-67. PMID: 11376920.
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    253. McCance-Katz EF, Kosten TA, Kosten TR. Going from the bedside back to the bench with ecopipam: a new strategy for cocaine pharmacotherapy development. Psychopharmacology (Berl). 2001 Jun; 155(4):327-9. PMID: 11441421.
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    254. Petry NM, Petrakis I, Trevisan L, Wiredu G, Boutros NN, Martin B, Kosten TR. Contingency management interventions: from research to practice. Am J Psychiatry. 2001 May; 158(5):694-702. PMID: 11329388.
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    255. D'Souza DC, Kosten TR. Cannabinoid antagonists: a treatment in search of an illness. Arch Gen Psychiatry. 2001 Apr; 58(4):330-1. PMID: 11296092.
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    256. Stine SM, Grillon CG, Morgan CA, Kosten TR, Charney DS, Krystal JH. Methadone patients exhibit increased startle and cortisol response after intravenous yohimbine. Psychopharmacology (Berl). 2001 Mar; 154(3):274-81. PMID: 11351934.
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    257. Jacobsen LK, Giedd JN, Kreek MJ, Gottschalk C, Kosten TR. Quantitative medial temporal lobe brain morphology and hypothalamic-pituitary-adrenal axis function in cocaine dependence: a preliminary report. Drug Alcohol Depend. 2001 Mar 1; 62(1):49-56. PMID: 11173167.
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    258. Jacobsen LK, Giedd JN, Gottschalk C, Kosten TR, Krystal JH. Quantitative morphology of the caudate and putamen in patients with cocaine dependence. Am J Psychiatry. 2001 Mar; 158(3):486-9. PMID: 11229995.
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    259. Sernyak MJ, Kosten TR, Fontana A, Rosenheck R. Neuroleptic use in the treatment of Post-Traumatic Stress Disorder. Psychiatr Q. 2001; 72(3):197-213. PMID: 11467155.
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    260. McCance-Katz EF, Rainey PM, Friedland G, Kosten TR, Jatlow P. Effect of opioid dependence pharmacotherapies on zidovudine disposition. Am J Addict. 2001; 10(4):296-307. PMID: 11783744.
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    261. Singha AK, McCance-Katz EF, Petrakis I, Kosten TR, Oliveto A. Sex differences in self-reported and physiological response to oral cocaine and placebo in humans. Am J Drug Alcohol Abuse. 2000 Nov; 26(4):643-57. PMID: 11097197.
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    262. George TP, Ziedonis DM, Feingold A, Pepper WT, Satterburg CA, Winkel J, Rounsaville BJ, Kosten TR. Nicotine transdermal patch and atypical antipsychotic medications for smoking cessation in schizophrenia. Am J Psychiatry. 2000 Nov; 157(11):1835-42. PMID: 11058482.
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    263. Jacobsen LK, Staley JK, Zoghbi SS, Seibyl JP, Kosten TR, Innis RB, Gelernter J. Prediction of dopamine transporter binding availability by genotype: a preliminary report. Am J Psychiatry. 2000 Oct; 157(10):1700-3. PMID: 11007732.
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    264. Avants SK, Margolin A, Holford TR, Kosten TR. A randomized controlled trial of auricular acupuncture for cocaine dependence. Arch Intern Med. 2000 Aug 14-28; 160(15):2305-12. PMID: 10927727.
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    265. Kosten TR, Fontana A, Sernyak MJ, Rosenheck R. Benzodiazepine use in posttraumatic stress disorder among veterans with substance abuse. J Nerv Ment Dis. 2000 Jul; 188(7):454-9. PMID: 10919705.
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    266. Jacobsen LK, Staley JK, Malison RT, Zoghbi SS, Seibyl JP, Kosten TR, Innis RB. Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients. Am J Psychiatry. 2000 Jul; 157(7):1134-40. PMID: 10873923.
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    267. George TP, Chawarski MC, Pakes J, Carroll KM, Kosten TR, Schottenfeld RS. Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trial. Biol Psychiatry. 2000 Jun 15; 47(12):1080-6. PMID: 10862808.
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    268. Schottenfeld RS, Pakes J, O'Connor P, Chawarski M, Oliveto A, Kosten TR. Thrice-weekly versus daily buprenorphine maintenance. Biol Psychiatry. 2000 Jun 15; 47(12):1072-9. PMID: 10862807.
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    269. Farren CK, Hameedi FA, Rosen MA, Woods S, Jatlow P, Kosten TR. Significant interaction between clozapine and cocaine in cocaine addicts. Drug Alcohol Depend. 2000 May 1; 59(2):153-63. PMID: 10891628.
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    270. Sevarino KA, Oliveto A, Kosten TR. Neurobiological adaptations to psychostimulants and opiates as a basis of treatment development. Ann N Y Acad Sci. 2000; 909:51-87. PMID: 10911924.
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    271. Gottschalk PC, Jacobsen LK, Kosten TR. Current concepts in pharmacotherapy of substance abuse. Curr Psychiatry Rep. 1999 Dec; 1(2):172-8. PMID: 11122921.
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    272. Singha AK, McCance-Katz EF, Heck SA, Kosten TR, Oliveto A. Individual differences in humans responding under a cocaine discrimination procedure: discriminators versus nondiscriminators. Exp Clin Psychopharmacol. 1999 Nov; 7(4):391-8. PMID: 10609974.
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    273. Oliveto AH, Feingold A, Schottenfeld R, Jatlow P, Kosten TR. Desipramine in opioid-dependent cocaine abusers maintained on buprenorphine vs methadone. Arch Gen Psychiatry. 1999 Sep; 56(9):812-20. PMID: 12884887.
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    274. Rosen MI, Kosten TR, Kreek MJ. The effects of naltrexone maintenance on the response to yohimbine in healthy volunteers. Biol Psychiatry. 1999 Jun 15; 45(12):1636-45. PMID: 10376126.
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    275. Kosten TR, Woods SW, Rosen MI, Pearsall HR. Interactions of cocaine with nimodipine: a brief report. Am J Addict. 1999; 8(1):77-81. PMID: 10189518.
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    276. Kosten TR, Markou A, Koob GF. Depression and stimulant dependence: neurobiology and pharmacotherapy. J Nerv Ment Dis. 1998 Dec; 186(12):737-45. PMID: 9865811.
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    277. Kosten TR. Images in psychiatry. Marie Nyswander, 1919-1986. Am J Psychiatry. 1998 Dec; 155(12):1766. PMID: 9842790.
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    278. Avants SK, Margolin A, Kosten TR, Rounsaville BJ, Schottenfeld RS. When is less treatment better? The role of social anxiety in matching methadone patients to psychosocial treatments. J Consult Clin Psychol. 1998 Dec; 66(6):924-31. PMID: 9874905.
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    279. Rosen MI, Pearsall HR, Kosten TR. The effect of lamotrigine on naloxone-precipitated opiate withdrawal. Drug Alcohol Depend. 1998 Oct 1; 52(2):173-6. PMID: 9800147.
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    281. McCance-Katz EF, Kosten TR, Jatlow P. Concurrent use of cocaine and alcohol is more potent and potentially more toxic than use of either alone--a multiple-dose study. Biol Psychiatry. 1998 Aug 15; 44(4):250-9. PMID: 9715356.
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    282. O'Connor PG, Oliveto AH, Shi JM, Triffleman EG, Carroll KM, Kosten TR, Rounsaville BJ, Pakes JA, Schottenfeld RS. A randomized trial of buprenorphine maintenance for heroin dependence in a primary care clinic for substance users versus a methadone clinic. Am J Med. 1998 Aug; 105(2):100-5. PMID: 9727815.
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    283. Malison RT, McCance E, Carpenter LL, Baldwin RM, Seibyl JP, Price LH, Kosten TR, Innis RB. [123I]beta-CIT SPECT imaging of dopamine transporter availability after mazindol administration in human cocaine addicts. Psychopharmacology (Berl). 1998 Jun; 137(4):321-5. PMID: 9676890.
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    284. Malison RT, Best SE, van Dyck CH, McCance EF, Wallace EA, Laruelle M, Baldwin RM, Seibyl JP, Price LH, Kosten TR, Innis RB. Elevated striatal dopamine transporters during acute cocaine abstinence as measured by [123I] beta-CIT SPECT. Am J Psychiatry. 1998 Jun; 155(6):832-4. PMID: 9619159.
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    285. Kosten TR. Addiction as a brain disease. Am J Psychiatry. 1998 Jun; 155(6):711-3. PMID: 9619141.
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    286. Oliveto AH, Rosen MI, Kosten TA, Hameedi FA, Woods SW, Kosten TR. Hydromorphone-naloxone combinations in opioid-dependent humans under a naloxone novel-response discrimination procedure. Exp Clin Psychopharmacol. 1998 May; 6(2):169-78. PMID: 9608349.
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    287. Avants SK, Margolin A, DePhilippis D, Kosten TR. A comprehensive pharmacologic-psychosocial treatment program for HIV-seropositive cocaine- and opioid-dependent patients. Preliminary findings. J Subst Abuse Treat. 1998 May-Jun; 15(3):261-5. PMID: 9633038.
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    288. Oliveto AH, McCance-Katz E, Singha A, Hameedi F, Kosten TR. Effects of d-amphetamine and caffeine in humans under a cocaine discrimination procedure. Behav Pharmacol. 1998 May; 9(3):207-17. PMID: 9832935.
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    289. Kosten TR, Cheeves C, Palumbo J, Seibyl JP, Price LH, Woods SW. Regional cerebral blood flow during acute and chronic abstinence from combined cocaine-alcohol abuse. Drug Alcohol Depend. 1998 May 1; 50(3):187-95. PMID: 9649971.
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    290. McCance-Katz EF, Kosten TR, Jatlow P. Chronic disulfiram treatment effects on intranasal cocaine administration: initial results. Biol Psychiatry. 1998 Apr 1; 43(7):540-3. PMID: 9547934.
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    291. Markou A, Kosten TR, Koob GF. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology. 1998 Mar; 18(3):135-74. PMID: 9471114.
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    292. Bowers MB, Malison RT, Seibyl JP, Kosten TR. Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal. Biol Psychiatry. 1998 Feb 15; 43(4):278-81. PMID: 9513737.
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    293. Margolin A, Avants SK, DePhilippis D, Kosten TR. A preliminary investigation of lamotrigine for cocaine abuse in HIV-seropositive patients. Am J Drug Alcohol Abuse. 1998 Feb; 24(1):85-101. PMID: 9513631.
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    294. O'Connor PG, Kosten TR. Rapid and ultrarapid opioid detoxification techniques. JAMA. 1998 Jan 21; 279(3):229-34. PMID: 9438745.
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    295. Oliveto AH, Farren C, Kosten TR. Effect of LAAM dose on opiate use in opioid-dependent patients. A pilot study. Am J Addict. 1998; 7(4):272-82. PMID: 9809131.
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    296. Kosten TR. The pharmacotherapy of relapse prevention using anticonvulsants. Am J Addict. 1998; 7(3):205-9. PMID: 9702288.
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    297. Schottenfeld RS, Pakes JR, Kosten TR. Prognostic factors in Buprenorphine- versus methadone-maintained patients. J Nerv Ment Dis. 1998 Jan; 186(1):35-43. PMID: 9457145.
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    298. Kosten TR. Pharmacotherapy of cerebral ischemia in cocaine dependence. Drug Alcohol Depend. 1998 Jan 1; 49(2):133-44. PMID: 9543650.
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    299. Kosten TR, Rosen MI, McMahon TL, Bridge TP, O'Malley SS, Pearsall R, O'Connor PG. Treatment of early AIDS dementia in intravenous drug users: high versus low dose peptide T. Am J Drug Alcohol Abuse. 1997 Nov; 23(4):543-53. PMID: 9366972.
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    300. O'Connor PG, Carroll KM, Shi JM, Schottenfeld RS, Kosten TR, Rounsaville BJ. Three methods of opioid detoxification in a primary care setting. A randomized trial. Ann Intern Med. 1997 Oct 1; 127(7):526-30. PMID: 9313020.
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    301. Avants SK, Margolin A, McMahon TJ, Kosten TR. Association between self-report of cognitive impairment, HIV status, and cocaine use in a sample of cocaine-dependent methadone-maintained patients. Addict Behav. 1997 Sep-Oct; 22(5):599-611. PMID: 9347062.
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    302. Schottenfeld RS, Pakes JR, Oliveto A, Ziedonis D, Kosten TR. Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse. Arch Gen Psychiatry. 1997 Aug; 54(8):713-20. PMID: 9283506.
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    303. Stine SM, Krystal JH, Petrakis IL, Jatlow PI, Heninger GR, Kosten TR, Charney DS. Effect of alpha-methyl-para-tyrosine on response to cocaine challenge. Biol Psychiatry. 1997 Aug 1; 42(3):181-90. PMID: 9232210.
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    304. Warner EA, Kosten TR, O'Connor PG. Pharmacotherapy for opioid and cocaine abuse. Med Clin North Am. 1997 Jul; 81(4):909-25. PMID: 9222260.
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    305. Hameedi FA, Woods SW, Rosen MI, Pearsall HR, Kosten TR. Dose dependent effects of yohimbine on methadone maintained patients. Am J Drug Alcohol Abuse. 1997 May; 23(2):327-33. PMID: 9143642.
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    306. Margolin A, Avants SK, Rounsaville B, Kosten TR, Schottenfeld RS. Motivational factors in cocaine pharmacotherapy trials with methadone-maintained patients: problems and paradoxes. J Psychoactive Drugs. 1997 Apr-Jun; 29(2):205-12. PMID: 9250948.
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    307. Rosen MI, Pearsall HR, Woods SW, Kosten TR. Effects of gamma-hydroxybutyric acid (GHB) in opioid-dependent patients. J Subst Abuse Treat. 1997 Mar-Apr; 14(2):149-54. PMID: 9258859.
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    308. Manji H, Chen G, Potter W, Kosten TR. Guanine nucleotide binding proteins in opioid-dependent patients. Biol Psychiatry. 1997 Jan 15; 41(2):130-4. PMID: 9018382.
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    309. Kosten TR, Ziedonis DM. Substance abuse and schizophrenia: editors' introduction. Schizophr Bull. 1997; 23(2):181-6. PMID: 9165628.
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    310. Silverman DG, Kosten TR, Jatlow PI, Gutter V, Fleming J, O'Connor TZ, Byck R. Decreased digital flow persists after the abatement of cocaine-induced hemodynamic stimulation. Anesth Analg. 1997 Jan; 84(1):46-50. PMID: 8988997.
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    311. van Dyck CH, McMahon TJ, Rosen MI, O'Malley SS, O'Connor PG, Lin CH, Pearsall HR, Woods SW, Kosten TR. Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study. J Neuropsychiatry Clin Neurosci. 1997; 9(1):29-36. PMID: 9017526.
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    312. O'Connor PG, Oliveto AH, Shi JM, Triffleman E, Carroll KM, Kosten TR, Rounsaville BJ. A pilot study of primary-care-based buprenorphine maintenance for heroin dependence. Am J Drug Alcohol Abuse. 1996 Nov; 22(4):523-31. PMID: 8911590.
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    313. Wallace EA, Wisniewski G, Zubal G, vanDyck CH, Pfau SE, Smith EO, Rosen MI, Sullivan MC, Woods SW, Kosten TR. Acute cocaine effects on absolute cerebral blood flow. Psychopharmacology (Berl). 1996 Nov; 128(1):17-20. PMID: 8944401.
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    314. Margolin A, Avants SK, Kosten TR. Abstinence symptomatology associated with cessation of chronic cocaine abuse among methadone-maintained patients. Am J Drug Alcohol Abuse. 1996 Aug; 22(3):377-88. PMID: 8841686.
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    315. Rosen MI, McMahon TJ, Woods SW, Pearsall HR, Kosten TR. A pilot study of dextromethorphan in naloxone-precipitated opiate withdrawal. Eur J Pharmacol. 1996 Jul 4; 307(3):251-7. PMID: 8836612.
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    316. Margolin A, Avants SK, Kosten TR. Pemoline for the treatment of cocaine dependence in methadone-maintained patients. J Psychoactive Drugs. 1996 Jul-Sep; 28(3):301-4. PMID: 8895115.
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    317. Rosen MI, Pearsall HR, Woods SW, Kosten TR. The effect of gamma-hydroxybutyric acid on naloxone-precipitated opiate withdrawal. Neuropsychopharmacology. 1996 Mar; 14(3):187-93. PMID: 8866702.
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    318. Rosen MI, McMahon TJ, Hameedi FA, Pearsall HR, Woods SW, Kreek MJ, Kosten TR. Effect of clonidine pretreatment on naloxone-precipitated opiate withdrawal. J Pharmacol Exp Ther. 1996 Mar; 276(3):1128-35. PMID: 8786543.
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    320. Margolin A, Kosten TR, Avants SK, Wilkins J, Ling W, Beckson M, Arndt IO, Cornish J, Ascher JA, Li SH, et al. A multicenter trial of bupropion for cocaine dependence in methadone-maintained patients. Drug Alcohol Depend. 1995 Dec; 40(2):125-31. PMID: 8745134.
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    321. Oliveto A, Kosten TR, Schottenfeld R, Falcioni J, Ziedonis D. Desipramine, amantadine, or fluoxetine in buprenorphine-maintained cocaine users. J Subst Abuse Treat. 1995 Nov-Dec; 12(6):423-8. PMID: 8749726.
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    322. Rosen MI, McMahon TJ, Margolin A, Gill TS, Woods SW, Pearsall HR, Kreek MJ, Kosten TR. Reliability of sequential naloxone challenge tests. Am J Drug Alcohol Abuse. 1995 Nov; 21(4):453-67. PMID: 8561097.
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    323. Margolin A, Avants SK, Kosten TR. Mazindol for relapse prevention to cocaine abuse in methadone-maintained patients. Am J Drug Alcohol Abuse. 1995 Nov; 21(4):469-81. PMID: 8561098.
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    324. Stine SM, Krystal JH, Kosten TR, Charney DS. Mazindol treatment for cocaine dependence. Drug Alcohol Depend. 1995 Oct; 39(3):245-52. PMID: 8556974.
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    325. McCance EF, Price LH, Kosten TR, Jatlow PI. Cocaethylene: pharmacology, physiology and behavioral effects in humans. J Pharmacol Exp Ther. 1995 Jul; 274(1):215-23. PMID: 7616402.
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    326. Avants SK, Margolin A, Chang P, Kosten TR, Birch S. Acupuncture for the treatment of cocaine addiction. Investigation of a needle puncture control. J Subst Abuse Treat. 1995 May-Jun; 12(3):195-205. PMID: 7474027.
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    327. Satel SL, Krystal JH, Delgado PL, Kosten TR, Charney DS. Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry. 1995 May; 152(5):778-83. PMID: 7726319.
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    328. Aronson SC, Black JE, McDougle CJ, Scanley BE, Jatlow P, Kosten TR, Heninger GR, Price LH. Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology (Berl). 1995 May; 119(2):179-85. PMID: 7659765.
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    329. Hameedi FA, Rosen MI, McCance-Katz EF, McMahon TJ, Price LH, Jatlow PI, Woods SW, Kosten TR. Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans. Biol Psychiatry. 1995 Apr 15; 37(8):560-3. PMID: 7619981.
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    330. Kosten TR, Rayford BS. Effects of ethnicity on low-dose opiate stabilization. J Subst Abuse Treat. 1995 Mar-Apr; 12(2):111-6. PMID: 7623388.
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    332. Krystal JH, Woods SW, Kosten TR, Rosen MI, Seibyl JP, van Dyck CC, Price LH, Zubal IG, Hoffer PB, Charney DS. Opiate dependence and withdrawal: preliminary assessment using single photon emission computerized tomography (SPECT). Am J Drug Alcohol Abuse. 1995 Feb; 21(1):47-63. PMID: 7762544.
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    333. Margolin A, Avants SK, Chang P, Birch S, Kosten TR. A single-blind investigation of four auricular needle puncture configurations. Am J Chin Med. 1995; 23(2):105-14. PMID: 7572770.
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    334. Lago JA, Kosten TR. Stimulant withdrawal. Addiction. 1994 Nov; 89(11):1477-81. PMID: 7841859.
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    335. Margolin A, Avants SK, Kosten TR. Cue-elicited cocaine craving and autogenic relaxation. Association with treatment outcome. J Subst Abuse Treat. 1994 Nov-Dec; 11(6):549-52. PMID: 7884838.
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    336. Stine SM, Kosten TR. Reduction of opiate withdrawal-like symptoms by cocaine abuse during methadone and buprenorphine maintenance. Am J Drug Alcohol Abuse. 1994 Nov; 20(4):445-58. PMID: 7832179.
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    337. Meandzija B, O'Connor PG, Fitzgerald B, Rounsaville BJ, Kosten TR. HIV infection and cocaine use in methadone maintained and untreated intravenous drug users. Drug Alcohol Depend. 1994 Oct; 36(2):109-13. PMID: 7851277.
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    338. McDougle CJ, Black JE, Malison RT, Zimmermann RC, Kosten TR, Heninger GR, Price LH. Noradrenergic dysregulation during discontinuation of cocaine use in addicts. Arch Gen Psychiatry. 1994 Sep; 51(9):713-9. PMID: 8080348.
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    339. Rinder HM, Ault KA, Jatlow PI, Kosten TR, Smith BR. Platelet alpha-granule release in cocaine users. Circulation. 1994 Sep; 90(3):1162-7. PMID: 7522132.
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    340. Rosen MI, Wallace EA, McMahon TJ, Pearsall HR, Woods SW, Price LH, Kosten TR. Buprenorphine: duration of blockade of effects of intramuscular hydromorphone. Drug Alcohol Depend. 1994 Apr; 35(2):141-9. PMID: 7519977.
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    341. Avants SK, Margolin A, Kosten TR. Cocaine abuse in methadone maintenance programs: integrating pharmacotherapy with psychosocial interventions. J Psychoactive Drugs. 1994 Apr-Jun; 26(2):137-46. PMID: 7931858.
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    342. Ziedonis DM, Kosten TR, Glazer WM, Frances RJ. Nicotine dependence and schizophrenia. Hosp Community Psychiatry. 1994 Mar; 45(3):204-6. PMID: 7910577.
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    343. Avants SK, Margolin A, Kosten TR, Singer JL. Changes concurrent with initiation of abstinence from cocaine abuse. J Subst Abuse Treat. 1993 Nov-Dec; 10(6):577-83. PMID: 8308943.
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    344. Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE. Alprazolam and benzodiazepine dependence. J Clin Psychiatry. 1993 Oct; 54 Suppl:64-75; discussion 76-7. PMID: 8262891.
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    345. Schottenfeld RS, Pakes J, Ziedonis D, Kosten TR. Buprenorphine: dose-related effects on cocaine and opioid use in cocaine-abusing opioid-dependent humans. Biol Psychiatry. 1993 Jul 1-15; 34(1-2):66-74. PMID: 8373940.
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    347. Satel SL, Kosten TR, Schuckit MA, Fischman MW. Should protracted withdrawal from drugs be included in DSM-IV? Am J Psychiatry. 1993 May; 150(5):695-704. PMID: 8097618.
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    348. Kosten TR. Clinical and research perspectives on cocaine abuse: the pharmacotherapy of cocaine abuse. NIDA Res Monogr. 1993; 135:48-56. PMID: 8289903.
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    349. McCance-Katz EF, Price LH, McDougle CJ, Kosten TR, Black JE, Jatlow PI. Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology (Berl). 1993; 111(1):39-46. PMID: 7870932.
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    350. Margolin A, Chang P, Avants SK, Kosten TR. Effects of sham and real auricular needling: implications for trials of acupuncture for cocaine addiction. Am J Chin Med. 1993; 21(2):103-11. PMID: 8237887.
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    351. Kosten TA, Gawin FH, Kosten TR, Rounsaville BJ. Gender differences in cocaine use and treatment response. J Subst Abuse Treat. 1993 Jan-Feb; 10(1):63-6. PMID: 8450576.
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    354. McDougle CJ, Price LH, Palumbo JM, Kosten TR, Heninger GR, Kleber HD. Dopaminergic responsivity during cocaine abstinence: a pilot study. Psychiatry Res. 1992 Jul; 43(1):77-85. PMID: 1359594.
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    355. Stine SM, Kosten TR. Use of drug combinations in treatment of opioid withdrawal. J Clin Psychopharmacol. 1992 Jun; 12(3):203-9. PMID: 1629388.
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    356. Closser MH, Kosten TR. Alcohol and cocaine abuse. A comparison of epidemiology and clinical characteristics. Recent Dev Alcohol. 1992; 10:115-28. PMID: 1317046.
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    357. Kosten TR. Pharmacological approaches to cocaine dependence. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:70A-71A. PMID: 1498999.
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    358. Nigam R, Schottenfeld R, Kosten TR. Treatment of dual diagnosis patients: a relapse prevention group approach. J Subst Abuse Treat. 1992; 9(4):305-9. PMID: 1362227.
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    361. Chang G, Carroll KM, Behr HM, Kosten TR. Improving treatment outcome in pregnant opiate-dependent women. J Subst Abuse Treat. 1992; 9(4):327-30. PMID: 1479630; PMCID: PMC3677856.
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    363. Kosten TA, Bianchi MS, Kosten TR. The predictive validity of the dependence syndrome in opiate abusers. Am J Drug Alcohol Abuse. 1992; 18(2):145-56. PMID: 1562012.
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    365. Kosten TA, Kosten TR. Pharmacological blocking agents for treating substance abuse. J Nerv Ment Dis. 1991 Oct; 179(10):583-92. PMID: 1919542.
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    366. Ziedonis DM, Kosten TR. Pharmacotherapy improves treatment outcome in depressed cocaine addicts. J Psychoactive Drugs. 1991 Oct-Dec; 23(4):417-25. PMID: 1813613.
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    367. Kosten TR, Rounsaville BJ, Kosten TA, Merikangas K. Gender differences in the specificity of alcoholism transmission among the relatives of opioid addicts. J Nerv Ment Dis. 1991 Jul; 179(7):392-400. PMID: 1869867.
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    368. Kosten TR, Frank JB, Dan E, McDougle CJ, Giller EL. Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine. J Nerv Ment Dis. 1991 Jun; 179(6):366-70. PMID: 2051152.
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    369. Kosten TR, Morgan C, Kleber HD. Treatment of heroin addicts using buprenorphine. Am J Drug Alcohol Abuse. 1991 Jun; 17(2):119-28. PMID: 1862786.
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    370. Rosen MI, Kosten TR. Buprenorphine: beyond methadone? Hosp Community Psychiatry. 1991 Apr; 42(4):347-9. PMID: 2050347.
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    371. Kosten TR. Medications development and the war on drugs: victims of the Gulf war? Biol Psychiatry. 1991 Mar 15; 29(6):521-3. PMID: 2054428.
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    372. Mason JW, Kosten TR, Giller EL. Multidimensional hormonal discrimination of paranoid schizophrenic from bipolar manic patients. Biol Psychiatry. 1991 Mar 1; 29(5):457-66. PMID: 2018819.
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    374. Woods SW, O'Malley SS, Martini BL, McDougle CJ, Price LH, Krystal JH, Hoffer PB, Kosten TR. SPECT regional cerebral blood flow and neuropsychological testing in non-demented HIV-positive drug abusers: preliminary results. Prog Neuropsychopharmacol Biol Psychiatry. 1991; 15(5):649-62. PMID: 1956993.
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    375. Ziedonis DM, Kosten TR. Depression as a prognostic factor for pharmacological treatment of cocaine dependence. Psychopharmacol Bull. 1991; 27(3):337-43. PMID: 1775608.
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    376. Kosten TR. Client issues in drug abuse treatment: addressing multiple drug abuse. NIDA Res Monogr. 1991; 106:136-51. PMID: 1922284.
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    377. Kosten TR, Wahby V, Giller E, Mason J. The dexamethasone suppression test and thyrotropin-releasing hormone stimulation test in posttraumatic stress disorder. Biol Psychiatry. 1990 Oct 15; 28(8):657-64. PMID: 2122916.
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    379. Kosten TR. Neurobiology of abused drugs. Opioids and stimulants. J Nerv Ment Dis. 1990 Apr; 178(4):217-27. PMID: 2156952.
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    380. Frank JB, Kosten TR, Giller EL. Antidepressants in the treatment of PTSD. Am J Psychiatry. 1990 Feb; 147(2):260. PMID: 2301678.
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    381. Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Opioid antagonist challenges in buprenorphine maintained patients. Drug Alcohol Depend. 1990 Feb; 25(1):73-8. PMID: 2323312.
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    382. Kosten TA, Kosten TR, Rounsaville BJ. Cocaine symptoms are predicted by familial psychopathology. NIDA Res Monogr. 1990; 105:603-4. PMID: 1876139.
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    383. Kosten TA, Kosten TR. The dependence syndrome concept as applied to alcohol and other substances of abuse. Recent Dev Alcohol. 1990; 8:47-68. PMID: 2185524.
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    384. Diakogiannis IA, Steinberg M, Kosten TR. Mazindol treatment of cocaine abuse. A double-blind investigation. NIDA Res Monogr. 1990; 105:514. PMID: 1876105.
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    385. Kosten TR, Morgan C, Kosten TA. Depressive symptoms during buprenorphine treatment of opioid abusers. J Subst Abuse Treat. 1990; 7(1):51-4. PMID: 2313769.
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    386. Kosten TR, Bryant K, Rounsaville BJ. The SCID: a clinical instrument for assessing psychiatric disorders. NIDA Res Monogr. 1990; 105:213-9. PMID: 1876002.
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    387. Kosten TR, Gawin FH, Morgan C, Nelson JC, Jatlow P. Evidence for altered desipramine disposition in methadone-maintained patients treated for cocaine abuse. Am J Drug Alcohol Abuse. 1990; 16(3-4):329-36. PMID: 2288330.
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    389. Kosten TA, Kosten TR. Cocaine abuse and opioid withdrawal. Lancet. 1989 Jul 15; 2(8655):165-6. PMID: 2567937.
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    390. Kosten TR. Pharmacotherapeutic interventions for cocaine abuse. Matching patients to treatments. J Nerv Ment Dis. 1989 Jul; 177(7):379-89. PMID: 2664072.
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    391. Mason JW, Kennedy JL, Kosten TR, Giller EL. Serum thyroxine levels in schizophrenic and affective disorder diagnostic subgroups. J Nerv Ment Dis. 1989 Jun; 177(6):351-8. PMID: 2723624.
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    392. Gawin FH, Kleber HD, Byck R, Rounsaville BJ, Kosten TR, Jatlow PI, Morgan C. Desipramine facilitation of initial cocaine abstinence. Arch Gen Psychiatry. 1989 Feb; 46(2):117-21. PMID: 2492422.
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    393. Kosten TA, Kosten TR, Rounsaville BJ. Personality disorders in opiate addicts show prognostic specificity. J Subst Abuse Treat. 1989; 6(3):163-8. PMID: 2795705.
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    394. Southwick S, Mason JW, Giller EL, Kosten TR. Serum thyroxine change and clinical recovery in psychiatric inpatients. Biol Psychiatry. 1989 Jan; 25(1):67-74. PMID: 2912510.
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    395. Kosten TR, Morgan CJ, Kleber HD. Buprenorphine treatment of cocaine abuse. NIDA Res Monogr. 1989; 95:461. PMID: 2641031.
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    396. Gawin FH, Morgan C, Kosten TR, Kleber HD. Double-blind evaluation of the effect of acute amantadine on cocaine craving. Psychopharmacology (Berl). 1989; 97(3):402-3. PMID: 2497490.
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    397. Kosten TR, Rounsaville BJ, Foley SH. Inpatient vs. outpatient cocaine abuse treatments. NIDA Res Monogr. 1989; 95:312-3. PMID: 2640976.
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    398. Kosten TR, Kleber HD, Morgan C. Role of opioid antagonists in treating intravenous cocaine abuse. Life Sci. 1989; 44(13):887-92. PMID: 2927249.
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    399. Jacobsen LK, Kosten TR. Naloxone challenge as a biological predictor of treatment outcome in opiate addicts. Am J Drug Alcohol Abuse. 1989; 15(4):355-66. PMID: 2596440.
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    400. Kosten TA, Jacobsen LK, Kosten TR. Severity of precipitated opiate withdrawal predicts drug dependence by DSM-III-R criteria. Am J Drug Alcohol Abuse. 1989; 15(3):237-50. PMID: 2763981.
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    401. Frank JB, Kosten TR, Giller EL, Dan E. A randomized clinical trial of phenelzine and imipramine for posttraumatic stress disorder. Am J Psychiatry. 1988 Oct; 145(10):1289-91. PMID: 3048121.
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    402. Mason JW, Giller EL, Kosten TR, Harkness L. Elevation of urinary norepinephrine/cortisol ratio in posttraumatic stress disorder. J Nerv Ment Dis. 1988 Aug; 176(8):498-502. PMID: 3404142.
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    403. Vining E, Kosten TR, Kleber HD. Clinical utility of rapid clonidine-naltrexone detoxification for opioid abusers. Br J Addict. 1988 May; 83(5):567-75. PMID: 3382815.
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    404. Kosten TR, Rounsaville BJ, Kleber HD. Antecedents and consequences of cocaine abuse among opioid addicts. A 2.5-year follow-up. J Nerv Ment Dis. 1988 Mar; 176(3):176-81. PMID: 3343591.
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    405. Mason JW, Giller EL, Kosten TR. Serum testosterone differences between patients with schizophrenia and those with affective disorder. Biol Psychiatry. 1988 Feb 15; 23(4):357-66. PMID: 3342266.
      View in: PubMed
    406. Kosten TR, Rounsaville BJ. Suicidality among opioid addicts: 2.5 year follow-up. Am J Drug Alcohol Abuse. 1988; 14(3):357-69. PMID: 3189257.
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    407. Kosten TR, Kleber HD. Buprenorphine detoxification from opioid dependence: a pilot study. Life Sci. 1988; 42(6):635-41. PMID: 3276999.
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    408. Kosten TR, Kleber HD. Rapid death during cocaine abuse: a variant of the neuroleptic malignant syndrome? Am J Drug Alcohol Abuse. 1988; 14(3):335-46. PMID: 3055940.
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    409. Kosten TR, Kleber HD. Differential diagnosis of psychiatric comorbidity in substance abusers. J Subst Abuse Treat. 1988; 5(4):201-6. PMID: 3216436.
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    410. Kosten TR, Rounsaville BJ, Babor TF, Spitzer RL, Williams JB. Substance-use disorders in DSM-III-R. Evidence for the dependence syndrome across different psychoactive substances. Br J Psychiatry. 1987 Dec; 151:834-43. PMID: 2901887.
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    411. Kosten TR, Schumann B, Wright D, Carney MK, Gawin FH. A preliminary study of desipramine in the treatment of cocaine abuse in methadone maintenance patients. J Clin Psychiatry. 1987 Nov; 48(11):442-4. PMID: 3680185.
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    412. Kosten TR, Kreek MJ, Swift C, Carney MK, Ferdinands L. Beta endorphin levels in CSF during methadone maintenance. Life Sci. 1987 Aug 31; 41(9):1071-6. PMID: 2956475.
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    413. Rounsaville BJ, Kosten TR, Williams JB, Spitzer RL. A field trial of DSM-III-R psychoactive substance dependence disorders. Am J Psychiatry. 1987 Mar; 144(3):351-5. PMID: 3826436.
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    414. Kosten TR, Rounsaville BJ, Kleber HD. A 2.5-year follow-up of cocaine use among treated opioid addicts. Have our treatments helped? Arch Gen Psychiatry. 1987 Mar; 44(3):281-4. PMID: 3827521.
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    415. Jacobs SC, Mason J, Kosten TR, Kasl SV, Ostfeld AM, Wahby V. Urinary free cortisol and separation anxiety early in the course of bereavement and threatened loss. Biol Psychiatry. 1987 Feb; 22(2):148-52. PMID: 3814667.
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    416. Rounsaville BJ, Kosten TR, Kleber HD. The antecedents and benefits of achieving abstinence in opioid addicts: a 2.5-year follow-up study. Am J Drug Alcohol Abuse. 1987; 13(3):213-29. PMID: 3687888.
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    417. Kosten TR, Rounsaville BJ. Source of income as a predictor in opioid addicts: 2.5 year follow-up. NIDA Res Monogr. 1987; 76:196-9. PMID: 3125447.
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    418. Kosten TR, Jalali B, Steidl JH, Kleber HD. Relationship of marital structure and interactions to opiate abuse relapse. Am J Drug Alcohol Abuse. 1987; 13(4):387-99. PMID: 3687898.
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    419. Kosten TR, Rounsaville BJ, Babor TF, Spitzer RL, Williams JB. The dependence syndrome across different psychoactive substances: revised DSM-III. NIDA Res Monogr. 1987; 76:255-8. PMID: 3125454.
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    420. Kosten TR, Mason JW, Giller EL, Ostroff RB, Harkness L. Sustained urinary norepinephrine and epinephrine elevation in post-traumatic stress disorder. Psychoneuroendocrinology. 1987; 12(1):13-20. PMID: 3588809.
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    421. Kosten TR, Rounsaville BJ, Kleber HD. Multidimensionality and prediction of treatment outcome in opioid addicts: 2.5-year follow-up. Compr Psychiatry. 1987 Jan-Feb; 28(1):3-13. PMID: 3802797.
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    422. Kosten TR, Rounsaville BJ, Kleber HD. Predictors of 2.5-year outcome in opioid addicts: pretreatment source of income. Am J Drug Alcohol Abuse. 1987; 13(1-2):19-32. PMID: 3687883.
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    423. Kosten TR, Forrest JN. Treatment of severe lithium-induced polyuria with amiloride. Am J Psychiatry. 1986 Dec; 143(12):1563-8. PMID: 3538913.
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    424. Rounsaville BJ, Kosten TR, Kleber HD. Long-term changes in current psychiatric diagnoses of treated opiate addicts. Compr Psychiatry. 1986 Sep-Oct; 27(5):480-98. PMID: 3757496.
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    425. Kosten TR, Rounsaville BJ. Psychopathology in opioid addicts. Psychiatr Clin North Am. 1986 Sep; 9(3):515-32. PMID: 3774603.
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    426. Rounsaville BJ, Kosten TR, Weissman MM, Kleber HD. Prognostic significance of psychopathology in treated opiate addicts. A 2.5-year follow-up study. Arch Gen Psychiatry. 1986 Aug; 43(8):739-45. PMID: 3729668.
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    427. Kosten TR, Kreek MJ, Ragunath J, Kleber HD. A preliminary study of beta endorphin during chronic naltrexone maintenance treatment in ex-opiate addicts. Life Sci. 1986 Jul 7; 39(1):55-9. PMID: 2941636.
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    428. Rounsaville BJ, Kosten TR, Weissmann MM, Kleber HD. A 2.5-year follow-up of short-term interpersonal psychotherapy in methadone-maintained opiate addicts. Compr Psychiatry. 1986 May-Jun; 27(3):201-10. PMID: 3709134.
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    429. Mason JW, Giller EL, Kosten TR, Ostroff RB, Podd L. Urinary free-cortisol levels in posttraumatic stress disorder patients. J Nerv Ment Dis. 1986 Mar; 174(3):145-9. PMID: 3950596.
      View in: PubMed
    430. Kosten TR, Kreek MJ, Ragunath J, Kleber HD. Cortisol levels during chronic naltrexone maintenance treatment in ex-opiate addicts. Biol Psychiatry. 1986 Feb; 21(2):217-20. PMID: 3947698.
      View in: PubMed
    431. Jacobs SC, Mason JW, Kosten TR, Wahby V, Kasl SV, Ostfeld AM. Bereavement and catecholamines. J Psychosom Res. 1986; 30(4):489-96. PMID: 3761233.
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    432. Kosten TR, Rounsaville BJ, Kleber HD. A 2.5 year follow-up of treatment retention and reentry among opioid addicts. J Subst Abuse Treat. 1986; 3(3):181-9. PMID: 3806731.
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    433. Kosten TR. Diagnosing depression with the DST and TRH in cocaine and opioid abusers. J Subst Abuse Treat. 1986; 3(1):47-9. PMID: 3090273.
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    434. Kosten TR, Hogan I, Jalali B, Steidl J, Kleber HD. The effect of multiple family therapy on addict family functioning: a pilot study. Adv Alcohol Subst Abuse. 1986; 5(3):51-62. PMID: 3728193.
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    435. Kosten TR, Gawin FH, Rounsaville BJ, Kleber HD. Abuse of cocaine with opioids: psychological aspects of treatment. NIDA Res Monogr. 1986; 67:278-82. PMID: 3092078.
      View in: PubMed
    436. Kosten TR, Kreek MJ, Ragunath J, Kleber HD. Chronic naltrexone effect on cortisol. NIDA Res Monogr. 1986; 67:362-5. PMID: 3092091.
      View in: PubMed
    437. Kosten TR, Gawin FH, Rounsaville BJ, Kleber HD. Cocaine abuse among opioid addicts: demographic and diagnostic factors in treatment. Am J Drug Alcohol Abuse. 1986; 12(1-2):1-16. PMID: 3788892.
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    438. Kosten TR, Rounsaville BJ, Kleber HD. Parental alcoholism in opioid addicts. J Nerv Ment Dis. 1985 Aug; 173(8):461-9. PMID: 4020363.
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    439. Kosten TR, Rounsaville BJ, Kleber HD. Ethnic and gender differences among opiate addicts. Int J Addict. 1985 Aug; 20(8):1143-62. PMID: 4077316.
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    440. Kleber HD, Kosten TR, Gaspari J, Topazian M. Nontolerance to the opioid antagonism of naltrexone. Biol Psychiatry. 1985 Jan; 20(1):66-72. PMID: 2981129.
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    441. Kosten TR, Rounsaville BJ, Kleber HD. Comparison of clinician ratings to self reports of withdrawal during clonidine detoxification of opiate addicts. Am J Drug Alcohol Abuse. 1985; 11(1-2):1-10. PMID: 3904410.
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    442. Kosten TR, Rounsaville BJ, Kleber HD. Relationship of depression to clonidine detoxification of opiate addicts. Compr Psychiatry. 1984 Sep-Oct; 25(5):503-8. PMID: 6488761.
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    443. Kosten TR, Kleber HD. Strategies to improve compliance with narcotic antagonists. Am J Drug Alcohol Abuse. 1984; 10(2):249-66. PMID: 6475891.
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    444. Kosten TR, Novak P, Kleber HD. Perceived marital and family environment of opiate addicts. Am J Drug Alcohol Abuse. 1984; 10(4):491-501. PMID: 6534181.
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    445. Kosten TR, Rounsaville BJ, Merikangas KR, Prusoff BA, Kleber HD. The relationship of the Maudsley Personality Inventory to depression in addicts. Compr Psychiatry. 1983 Nov-Dec; 24(6):535-42. PMID: 6653096.
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    446. Kosten TR, Jalali B, Hogan I, Kleber HD. Family denial as a prognostic factor in opiate addict treatment outcome. J Nerv Ment Dis. 1983 Oct; 171(10):611-6. PMID: 6619824.
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    447. Kosten TR, Rounsaville BJ, Kleber HD. Concurrent validity of the addiction severity index. J Nerv Ment Dis. 1983 Oct; 171(10):606-10. PMID: 6619823.
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    448. Kosten TR, Rounsaville BJ, Kleber HD. Relationship of depression to psychosocial stressors in heroin addicts. J Nerv Ment Dis. 1983 Feb; 171(2):97-104. PMID: 6822825.
      View in: PubMed
    449. Kosten TR, Rounsaville BJ, Kleber HD. DSM-III personality disorders in opiate addicts. Compr Psychiatry. 1982 Nov-Dec; 23(6):572-81. PMID: 7160176.
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    450. Kosten TR, Jalali B, Kleber HD. Complementary marital roles of male heroin addicts: evolution and intervention tactics. Am J Drug Alcohol Abuse. 1982-1983; 9(2):155-69. PMID: 7171079.
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