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WEHRENS, XANDER
One or more keywords matched the following items that are connected to
WEHRENS, XANDER
Item Type
Name
Academic Article
Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.
Academic Article
Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2.
Academic Article
Molecular determinants of altered contractility in heart failure.
Academic Article
Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice.
Academic Article
Altered function and regulation of cardiac ryanodine receptors in cardiac disease.
Academic Article
Defective cardiac ryanodine receptor regulation during atrial fibrillation.
Academic Article
Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor.
Academic Article
CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban.
Academic Article
Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression.
Academic Article
Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy.
Academic Article
Phosphorylation of RyR2 and shortening of RyR2 cluster spacing in spontaneously hypertensive rat with heart failure.
Academic Article
Exercise training during diabetes attenuates cardiac ryanodine receptor dysregulation.
Academic Article
Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.
Academic Article
Stress synchronizes calcium release and promotes SR calcium leak.
Academic Article
Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.
Academic Article
Calmodulin kinase II, sarcoplasmic reticulum Ca2+ leak, and atrial fibrillation.
Academic Article
CaMKII regulation of the cardiac ryanodine receptor and sarcoplasmic reticulum calcium release.
Academic Article
Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice.
Academic Article
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.
Academic Article
Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance.
Academic Article
Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.
Academic Article
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Academic Article
Ryanodine receptor phosphorylation, calcium/calmodulin-dependent protein kinase II, and life-threatening ventricular arrhythmias.
Academic Article
FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death.
Academic Article
Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak.
Academic Article
Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias.
Academic Article
Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model.
Academic Article
Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias.
Concept
Phosphorylation
Academic Article
Ryanodine receptor phosphorylation by oxidized CaMKII contributes to the cardiotoxic effects of cardiac glycosides.
Academic Article
Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease.
Academic Article
Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation.
Academic Article
CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.
Academic Article
Long-term simulated microgravity causes cardiac RyR2 phosphorylation and arrhythmias in mice.
Academic Article
The mitochondrial uniporter controls fight or flight heart rate increases.
Academic Article
CaMKIId mediates ?-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic ?-adrenergic stimulation.
Academic Article
Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy.
Academic Article
Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
Academic Article
A Single Protein Kinase A or Calmodulin Kinase II Site Does Not Control the Cardiac Pacemaker Ca2+ Clock.
Academic Article
Reversible redox modifications of ryanodine receptor ameliorate ventricular arrhythmias in the ischemic-reperfused heart.
Academic Article
CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.
Academic Article
Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy.
Academic Article
Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
Academic Article
Protein Phosphatase 2A Regulates Cardiac Na+ Channels.
Grant
Ryanodine receptor regulation in post-operative atrial fibrillation
Grant
Regulation of Sarcoplasmic Reticulum Calcium Release in Heart Failure
Academic Article
Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation.
Academic Article
Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation.
Academic Article
Phosphorylation-Dependent Interactome of Ryanodine Receptor Type 2 in the Heart.
Academic Article
Prolonged ?-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes and has implications for heart failure.
Academic Article
PHOSPHORYLATION OF RyR2 SIMULTANEOUSLY EXPANDS THE DYAD AND REARRANGES THE TETRAMERS.
Academic Article
PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation.
Academic Article
Phosphorylation of RyR2 simultaneously expands the dyad and rearranges the tetramers.
Search Criteria
Phosphorylation