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LICHTARGE, OLIVIER

One or more keywords matched the following items that are connected to LICHTARGE, OLIVIER

Item Type	Name
Academic Article	Correlated evolutionary pressure at interacting transcription factors and DNA response elements can guide the rational engineering of DNA binding specificity.
Academic Article	Evolutionary and structural feedback on selection of sequences for comparative analysis of proteins.
Academic Article	Cavity-aware motifs reduce false positives in protein function prediction.
Academic Article	Evolutionary Trace Annotation Server: automated enzyme function prediction in protein structures using 3D templates.
Academic Article	Algorithms for structural comparison and statistical analysis of 3D protein motifs.
Academic Article	Character and evolution of protein-protein interfaces.
Academic Article	Recurrent use of evolutionary importance for functional annotation of proteins based on local structural similarity.
Academic Article	ETAscape: analyzing protein networks to predict enzymatic function and substrates in Cytoscape.
Academic Article	A large-scale evaluation of computational protein function prediction.
Academic Article	Evolutionary trace report_maker: a new type of service for comparative analysis of proteins.
Academic Article	Rank information: a structure-independent measure of evolutionary trace quality that improves identification of protein functional sites.
Academic Article	Evolution: a guide to perturb protein function and networks.
Academic Article	Sequence and structure continuity of evolutionary importance improves protein functional site discovery and annotation.
Academic Article	The use of evolutionary patterns in protein annotation.
Academic Article	Function prediction from networks of local evolutionary similarity in protein structure.
Academic Article	An accurate, sensitive, and scalable method to identify functional sites in protein structures.
Academic Article	Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2.
Academic Article	ET viewer: an application for predicting and visualizing functional sites in protein structures.
Academic Article	Rapid detection of similarity in protein structure and function through contact metric distances.
Academic Article	The MASH pipeline for protein function prediction and an algorithm for the geometric refinement of 3D motifs.
Concept	Molecular Biology
Concept	Computational Biology
Academic Article	Prediction and experimental validation of enzyme substrate specificity in protein structures.
Academic Article	Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors.
Academic Article	Prediction and redesign of protein-protein interactions.
Academic Article	COMPUTING THERAPY FOR PRECISION MEDICINE: COLLABORATIVE FILTERING INTEGRATES AND PREDICTS MULTI-ENTITY INTERACTIONS.
Academic Article	REPURPOSING GERMLINE EXOMES OF THE CANCER GENOME ATLAS DEMANDS A CAUTIOUS APPROACH AND SAMPLE-SPECIFIC VARIANT FILTERING.
Academic Article	DISCOVERY OF FUNCTIONAL AND DISEASE PATHWAYS BY COMMUNITY DETECTION IN PROTEIN-PROTEIN INTERACTION NETWORKS.
Academic Article	HUMAN KINASES DISPLAY MUTATIONAL HOTSPOTS AT COGNATE POSITIONS WITHIN CANCER.
Academic Article	Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling.
Academic Article	Benchmarking predictions of allostery in liver pyruvate kinase in CAGI4.
Academic Article	Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI.
Academic Article	Objective assessment of the evolutionary action equation for the fitness effect of missense mutations across CAGI-blinded contests.
Academic Article	Multimodal network diffusion predicts future disease-gene-chemical associations.
Academic Article	Predicting venous thromboembolism risk from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.
Academic Article	Assessment of patient clinical descriptions and pathogenic variants from gene panel sequences in the CAGI-5 intellectual disability challenge.
Academic Article	Assessment of methods for predicting the effects of PTEN and TPMT protein variants.
Academic Article	Assessing the performance of in silico methods for predicting the pathogenicity of variants in the gene CHEK2, among Hispanic females with breast cancer.
Academic Article	Performance of computational methods for the evaluation of pericentriolar material 1 missense variants in CAGI-5.
Academic Article	Assessing predictions on fitness effects of missense variants in calmodulin.
Academic Article	Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants.
Academic Article	Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants.
Academic Article	CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation.
Academic Article	CAGI SickKids challenges: Assessment of phenotype and variant predictions derived from clinical and genomic data of children with undiagnosed diseases.
Academic Article	Assessment of predicted enzymatic activity of a-N-acetylglucosaminidase variants of unknown significance for CAGI 2016.
Academic Article	Graph-based information diffusion method for prioritizing functionally related genes in protein-protein interaction networks.
Academic Article	An Evolutionary Trace method defines functionally important bases and sites common to RNA families.
Academic Article	Genome interpretation using in silico predictors of variant impact.

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Biology